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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551337
Species: Mus musculus
RGD Object: Gene
Symbol: Spink1
Name: serine peptidase inhibitor, Kazal type 1
Acc ID: CHEBI:50859
Term: bexarotene
Definition: A retinoid that has formula C24H28O2.
Chemical ID: MESH:C095105
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Spink1increases expressionISOSpink1 (Rattus norvegicus)6480464CTDbexarotene results in increased expression of SPINK1 mRNAPMID:16648578
Spink1multiple interactionsISOSpink1 (Rattus norvegicus)6480464CTD[bexarotene co-treated with Tamoxifen] results in increased expression of SPINK1 mRNAPMID:17630414
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