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Gene: Gc (vitamin D binding protein) Mus musculus
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Symbol: Gc
Name: vitamin D binding protein
Description: Predicted to have actin binding activity and calcidiol binding activity. Involved in vitamin D metabolic process. Predicted to localize to several cellular components, including axon; extracellular space; and perinuclear region of cytoplasm. Is expressed in embryo; liver; and pancreas epithelium. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hypersensitivity disease (multiple); hepatocellular carcinoma; human immunodeficiency virus infectious disease; inflammatory bowel disease (multiple); and rheumatic fever. Orthologous to human GC (GC vitamin D binding protein); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; arsenite(3-).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DBP; gc-globulin; group specific component; group-specific component; VDB; vitamin D-binding protein
Orthologs:
Homo sapiens (human) : GC (GC vitamin D binding protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gc (GC, vitamin D binding protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gc (GC vitamin D binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : GC (GC vitamin D binding protein)
Canis lupus familiaris (dog) : GC (GC vitamin D binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gc (GC vitamin D binding protein)
Sus scrofa (pig) : GC (GC vitamin D binding protein)
Chlorocebus sabaeus (African green monkey) : GC (GC vitamin D binding protein)
Heterocephalus glaber (naked mole-rat) : Gc (GC vitamin D binding protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl589,417,522 - 89,457,898 (-)EnsemblGRCm38mm10GRCm38
GRCm38589,417,511 - 89,457,898 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37589,846,547 - 89,886,790 (-)NCBIGRCm37mm9NCBIm37
MGSCv36590,492,721 - 90,532,964 (-)NCBImm8
Celera587,554,559 - 87,593,435 (-)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Gc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10624
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.