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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pioglitazone
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Accession:CHEBI:8228 term browser browse the term
Definition:A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Synonyms:exact_synonym: 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
 related_synonym: (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione;   Formula=C19H20N2O3S;   InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);   InChIKey=HYAFETHFCAUJAY-UHFFFAOYSA-N;   SMILES=CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1;   pioglitazona;   pioglitazonum
 xref: Beilstein:3595485;   CAS:111025-46-8;   Chemspider:4663;   DrugBank:DB01132;   Drug_Central:2179;   HMDB:HMDB0015264;   KEGG:C07675;   KEGG:D08378;   LINCS:LSM-1592
 xref_mesh: MESH:C060836
 xref: PMID:12879407;   PMID:14522601;   PMID:17628757;   PMID:18215232;   PMID:20797618;   PMID:27842070;   PMID:33798599;   PMID:33864097;   PMID:33983968;   PMID:33995271;   PMID:34006325;   PMID:34009030;   Patent:EP193256;   Patent:US4687777;   Reaxys:3595485;   Wikipedia:Pioglitazone


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pioglitazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABAT mRNA CTD PMID:27935865 NCBI chr16:8,674,617...8,784,570
Ensembl chr16:8,674,596...8,784,575 		JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 affects expression
increases expression		 EXP
ISO		 pioglitazone affects the expression of ABCA1 protein
pioglitazone results in increased expression of ABCA1 mRNA; pioglitazone results in increased expression of ABCA1 protein		 CTD PMID:15381068 PMID:17961437 PMID:19201410 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCA4 ATP binding cassette subfamily A member 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCA4 mRNA CTD PMID:27935865 NCBI chr 1:93,992,834...94,121,148
Ensembl chr 1:93,992,834...94,121,148 		JBrowse link
G ABCA6 ATP binding cassette subfamily A member 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCA6 mRNA CTD PMID:27935865 NCBI chr17:69,078,702...69,141,895
Ensembl chr17:69,078,702...69,141,895 		JBrowse link
G ABCA8 ATP binding cassette subfamily A member 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCA8B mRNA CTD PMID:27935865 NCBI chr17:68,867,289...68,955,392
Ensembl chr17:68,867,289...68,955,392 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 increases expression EXP Pioglitazone results in increased expression of ABCB1 mRNA CTD PMID:31233785 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 decreases activity EXP pioglitazone results in decreased activity of ABCB11 protein CTD PMID:20829430 PMID:22646477 PMID:23956101 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCC9 mRNA CTD PMID:27935865 NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543 		JBrowse link
G ABI3BP ABI family member 3 binding protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABI3BP mRNA CTD PMID:27935865 NCBI chr 3:100,749,156...100,993,421
Ensembl chr 3:100,749,156...100,993,515 		JBrowse link
G ABLIM2 actin binding LIM protein family member 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABLIM2 mRNA CTD PMID:27935865 NCBI chr 4:7,965,327...8,158,813
Ensembl chr 4:7,965,310...8,158,832 		JBrowse link
G ABRA actin binding Rho activating protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABRA mRNA CTD PMID:27935865 NCBI chr 8:106,759,483...106,770,244
Ensembl chr 8:106,759,483...106,770,244 		JBrowse link
G ACAT1 acetyl-CoA acetyltransferase 1 decreases expression EXP pioglitazone results in decreased expression of ACAT1 mRNA CTD PMID:15381068 NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,147,603 		JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 decreases expression EXP Pioglitazone results in decreased expression of ACAT2 mRNA CTD PMID:30031879 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112 		JBrowse link
G ACE angiotensin I converting enzyme multiple interactions ISO pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE protein] CTD PMID:16979161 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACE2 angiotensin converting enzyme 2 increases expression
increases secretion		 ISO Pioglitazone results in increased expression of ACE2 protein
Pioglitazone results in increased secretion of ACE2 protein		 CTD PMID:24114819 PMID:24558317 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ACOD1 aconitate decarboxylase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of ACOD1 mRNA CTD PMID:27935865 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G ACTA1 actin alpha 1, skeletal muscle multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTA1 mRNA CTD PMID:27935865 NCBI chr 1:229,431,245...229,434,094
Ensembl chr 1:229,430,365...229,434,104 		JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO
EXP		 pioglitazone inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of ACTA2 mRNA]; pioglitazone inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
Pioglitazone inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]
pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]		 CTD PMID:15052691 PMID:16484506 PMID:18513333 PMID:32613381 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339 		JBrowse link
G ACTC1 actin alpha cardiac muscle 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTC1 mRNA CTD PMID:27935865 NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,107...34,795,589 		JBrowse link
G ACTG2 actin gamma 2, smooth muscle multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTG2 mRNA CTD PMID:27935865 NCBI chr 2:73,893,008...73,919,865
Ensembl chr 2:73,892,314...73,919,865 		JBrowse link
G ACTN2 actinin alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTN2 mRNA CTD PMID:27935865 NCBI chr 1:236,686,499...236,764,631
Ensembl chr 1:236,664,141...236,764,631 		JBrowse link
G ADAM23 ADAM metallopeptidase domain 23 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADAM23 mRNA CTD PMID:27935865 NCBI chr 2:206,443,532...206,621,127
Ensembl chr 2:206,443,532...206,621,127 		JBrowse link
G ADAM5 ADAM metallopeptidase domain 5 (pseudogene) multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADAM5 mRNA CTD PMID:27935865 NCBI chr 8:39,314,632...39,417,378
Ensembl chr 8:39,314,591...39,417,378 		JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 multiple interactions EXP pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ADAM9 mRNA] CTD PMID:20847119 NCBI chr 8:38,996,973...39,105,261
Ensembl chr 8:38,996,754...39,105,445 		JBrowse link
G ADCY5 adenylate cyclase 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADCY5 mRNA CTD PMID:27935865 NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090 		JBrowse link
G ADCYAP1R1 ADCYAP receptor type I multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADCYAP1R1 mRNA CTD PMID:27935865 NCBI chr 7:31,052,308...31,111,474
Ensembl chr 7:31,052,308...31,111,474 		JBrowse link
G ADHFE1 alcohol dehydrogenase iron containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADHFE1 mRNA CTD PMID:27935865 NCBI chr 8:66,432,504...66,468,907
Ensembl chr 8:66,432,492...66,468,907 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions
decreases expression
increases expression		 ISO
EXP		 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone results in increased expression of ADIPOQ mRNA]; [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of ADIPOQ mRNA; [Sodium Glutamate co-treated with Pioglitazone] results in increased expression of ADIPOQ protein; Pioglitazone promotes the reaction [Palmitates results in increased secretion of ADIPOQ protein]; PPARG protein affects the reaction [Pioglitazone results in increased expression of ADIPOQ mRNA]
Pioglitazone results in decreased expression of ADIPOQ protein
2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; octocrylene inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; Pioglitazone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; T 0070907 inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]
Pioglitazone inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ protein]; Pioglitazone inhibits the reaction [Fructose results in decreased secretion of ADIPOQ protein]
pioglitazone results in increased expression of ADIPOQ mRNA; pioglitazone results in increased expression of ADIPOQ protein		 CTD PMID:12927809 PMID:18303122 PMID:18513333 PMID:18815186 PMID:19048458 More... NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G ADM adrenomedullin multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ADM mRNA CTD PMID:20847119 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G ADORA1 adenosine A1 receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADORA1 mRNA CTD PMID:27935865 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405 		JBrowse link
G AGBL1 AGBL carboxypeptidase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGBL1 mRNA CTD PMID:27935865 NCBI chr15:86,079,620...87,031,476
Ensembl chr15:86,079,871...87,049,169 		JBrowse link
G AGER advanced glycosylation end-product specific receptor multiple interactions ISO Pioglitazone inhibits the reaction [Fructose results in increased expression of AGER protein] CTD PMID:25679220 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AGT angiotensinogen multiple interactions ISO pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 mRNA]; pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 protein] CTD PMID:25874449 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGTR1A mRNA CTD PMID:27935865 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AGTR2 angiotensin II receptor type 2 multiple interactions ISO [ANGPT2 protein binds to and results in increased activity of AGTR2 protein] promotes the reaction [pioglitazone binds to and results in increased activity of PPARG protein]; [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGTR2 mRNA CTD PMID:15992368 PMID:27935865 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G AIFM3 apoptosis inducing factor mitochondria associated 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AIFM3 mRNA CTD PMID:27935865 NCBI chr22:20,965,172...20,981,358
Ensembl chr22:20,965,108...20,981,360 		JBrowse link
G AJUBA ajuba LIM protein multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of AJUBA mRNA CTD PMID:20847119 NCBI chr14:22,971,177...22,982,551
Ensembl chr14:22,971,177...22,982,551 		JBrowse link
G ALPK3 alpha kinase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ALPK3 mRNA CTD PMID:27935865 NCBI chr15:84,817,356...84,873,479
Ensembl chr15:84,817,356...84,873,479 		JBrowse link
G AMIGO2 adhesion molecule with Ig like domain 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AMIGO2 mRNA CTD PMID:27935865 NCBI chr12:47,075,707...47,079,959
Ensembl chr12:47,075,707...47,079,959 		JBrowse link
G AMOTL2 angiomotin like 2 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of AMOTL2 mRNA CTD PMID:20847119 NCBI chr 3:134,355,345...134,375,417
Ensembl chr 3:134,355,347...134,375,479 		JBrowse link
G AMPD1 adenosine monophosphate deaminase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AMPD1 mRNA CTD PMID:27935865 NCBI chr 1:114,673,098...114,695,546
Ensembl chr 1:114,673,090...114,695,618 		JBrowse link
G ANGPT2 angiopoietin 2 multiple interactions ISO [ANGPT2 protein binds to and results in increased activity of AGTR2 protein] promotes the reaction [pioglitazone binds to and results in increased activity of PPARG protein] CTD PMID:15992368 NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409 		JBrowse link
G ANGPTL2 angiopoietin like 2 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ANGPTL2 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ANGPTL2 mRNA] CTD PMID:20847119 NCBI chr 9:127,087,348...127,122,635
Ensembl chr 9:127,087,348...127,122,635 		JBrowse link
G ANGPTL4 angiopoietin like 4 increases expression EXP Pioglitazone results in increased expression of ANGPTL4 mRNA CTD PMID:30031879 NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370 		JBrowse link
G ANK1 ankyrin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ANK1 mRNA CTD PMID:27935865 NCBI chr 8:41,653,225...41,896,741
Ensembl chr 8:41,653,220...41,896,741 		JBrowse link
G ANKRD37 ankyrin repeat domain 37 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ANKRD37 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ANKRD37 mRNA] CTD PMID:20847119 NCBI chr 4:185,396,841...185,400,723
Ensembl chr 4:185,396,021...185,400,628 		JBrowse link
G ANKRD63 ankyrin repeat domain 63 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ANKRD63 mRNA CTD PMID:27935865 NCBI chr15:40,278,372...40,283,064
Ensembl chr15:40,278,372...40,283,064 		JBrowse link
G ANO5 anoctamin 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ANO5 mRNA CTD PMID:27935865 NCBI chr11:22,192,473...22,283,357
Ensembl chr11:21,782,659...22,283,567 		JBrowse link
G ANOS1 anosmin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of WFDC17 mRNA CTD PMID:27935865 NCBI chr  X:8,528,874...8,732,137
Ensembl chr  X:8,528,874...8,732,137 		JBrowse link
G AOC3 amine oxidase copper containing 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AOC3 mRNA CTD PMID:27935865 NCBI chr17:42,851,199...42,858,124
Ensembl chr17:42,851,184...42,858,130 		JBrowse link
G AP1S2 adaptor related protein complex 1 subunit sigma 2 decreases expression EXP Pioglitazone results in decreased expression of AP1S2 mRNA CTD PMID:30031879 NCBI chr  X:15,825,806...15,854,813
Ensembl chr  X:15,825,806...15,854,931 		JBrowse link
G APC2 APC regulator of WNT signaling pathway 2 increases expression ISO pioglitazone results in increased expression of APC2 mRNA CTD PMID:21347706 NCBI chr19:1,446,230...1,473,244
Ensembl chr19:1,446,302...1,473,244 		JBrowse link
G APOB apolipoprotein B decreases expression EXP pioglitazone results in decreased expression of APOB protein CTD PMID:16324916 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOC1 apolipoprotein C1 multiple interactions EXP [Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in increased expression of APOC1 protein CTD PMID:16324916 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349 		JBrowse link
G APOC2 apolipoprotein C2 multiple interactions EXP
ISO		 [Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in decreased expression of APOC2 protein
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of APOC2 mRNA		 CTD PMID:16324916 PMID:27935865 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565 		JBrowse link
G APOC3 apolipoprotein C3 multiple interactions EXP [Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in decreased expression of APOC3 protein CTD PMID:16324916 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072 		JBrowse link
G APOL6 apolipoprotein L6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of APOL6 mRNA CTD PMID:27935865 NCBI chr22:35,648,446...35,668,404
Ensembl chr22:35,648,446...35,668,404 		JBrowse link
G APP amyloid beta precursor protein decreases expression
multiple interactions		 EXP
ISO		 pioglitazone results in decreased expression of APP protein mutant form
pioglitazone inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]; pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]		 CTD PMID:14586007 PMID:15817521 PMID:16407166 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G AQP7 aquaporin 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AQP7 mRNA CTD PMID:27935865 NCBI chr 9:33,383,191...33,402,568
Ensembl chr 9:33,383,179...33,402,682 		JBrowse link
G AR androgen receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AR mRNA CTD PMID:27935865 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G AREG amphiregulin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of AREG mRNA CTD PMID:27935865 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005 		JBrowse link
G ARMCX2 armadillo repeat containing X-linked 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ARMCX2 mRNA CTD PMID:27935865 NCBI chr  X:101,655,281...101,659,850
Ensembl chr  X:101,655,281...101,659,850 		JBrowse link
G ART1 ADP-ribosyltransferase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ART1 mRNA CTD PMID:27935865 NCBI chr11:3,645,128...3,664,416
Ensembl chr11:3,645,128...3,664,416 		JBrowse link
G ART2P ADP-ribosyltransferase 2, pseudogene multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of ART2A mRNA CTD PMID:27935865 NCBI chr11:72,520,951...72,521,640
Ensembl chr11:72,519,986...72,521,733 		JBrowse link
G ASB10 ankyrin repeat and SOCS box containing 10 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ASB10 mRNA CTD PMID:27935865 NCBI chr 7:151,175,698...151,187,792
Ensembl chr 7:151,175,698...151,187,832 		JBrowse link
G ASB14 ankyrin repeat and SOCS box containing 14 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ASB14 mRNA CTD PMID:27935865 NCBI chr 3:57,268,342...57,292,685
Ensembl chr 3:57,268,342...57,292,685 		JBrowse link
G ASB5 ankyrin repeat and SOCS box containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ASB5 mRNA CTD PMID:27935865 NCBI chr 4:176,213,673...176,277,524
Ensembl chr 4:176,213,673...176,277,571 		JBrowse link
G ATF3 activating transcription factor 3 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ATF3 mRNA CTD PMID:20847119 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ATP1A2 mRNA CTD PMID:27935865 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591 		JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ATP2A1 mRNA CTD PMID:27935865 NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466 		JBrowse link
G ATP5F1B ATP synthase F1 subunit beta decreases expression EXP pioglitazone results in decreased expression of ATP5F1B mRNA CTD PMID:20860658 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984 		JBrowse link
G AVPR1A arginine vasopressin receptor 1A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AVPR1A mRNA CTD PMID:27935865 NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201 		JBrowse link
G B4GALNT2 beta-1,4-N-acetyl-galactosaminyltransferase 2 (SID blood group) multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of B4GALNT2 mRNA CTD PMID:27935865 NCBI chr17:49,120,344...49,176,840
Ensembl chr17:49,132,460...49,176,840 		JBrowse link
G B4GALNT3 beta-1,4-N-acetyl-galactosaminyltransferase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of B4GALNT3 mRNA CTD PMID:27935865 NCBI chr12:459,939...563,509
Ensembl chr12:459,939...563,509 		JBrowse link
G BACE1 beta-secretase 1 multiple interactions
decreases expression
decreases activity		 EXP
ISO		 pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of and results in increased activity of BACE1 protein]
pioglitazone results in decreased expression of BACE1 mRNA
pioglitazone results in decreased activity of BACE1 protein
pioglitazone results in decreased expression of BACE1 mRNA; pioglitazone results in decreased expression of BACE1 protein		 CTD PMID:14586007 PMID:15817521 PMID:16407166 NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of BAX mRNA]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of BAX mRNA] CTD PMID:30130594 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCHE butyrylcholinesterase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BCHE mRNA CTD PMID:27935865 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462 		JBrowse link
G BCL11A BCL11 transcription factor A decreases expression EXP Pioglitazone results in decreased expression of BCL11A mRNA CTD PMID:30031879 NCBI chr 2:60,450,520...60,553,924
Ensembl chr 2:60,450,520...60,554,467 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in decreased expression of BCL2 mRNA]; Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased expression of BCL2 mRNA] CTD PMID:30130594 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions ISO Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BDNF protein] CTD PMID:32735850 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BEND5 BEN domain containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BEND5 mRNA CTD PMID:27935865 NCBI chr 1:48,727,519...48,776,891
Ensembl chr 1:48,727,519...48,776,969 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein multiple interactions ISO Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:32473317 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BHLHA15 basic helix-loop-helix family member a15 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BHLHA15 mRNA CTD PMID:27935865 NCBI chr 7:98,211,439...98,215,457
Ensembl chr 7:98,211,439...98,215,457 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 decreases expression EXP Pioglitazone results in decreased expression of BIRC3 mRNA CTD PMID:30031879 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BMP6 bone morphogenetic protein 6 increases expression EXP Pioglitazone results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G BPIFA4P BPI fold containing family A member 4, pseudogene multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of BPIFA5 mRNA CTD PMID:27935865 NCBI chr20:33,193,605...33,210,462
Ensembl chr20:33,193,585...33,210,462
Ensembl chr20:33,193,585...33,210,462 		JBrowse link
G BPIFB1 BPI fold containing family B member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BPIFB1 mRNA CTD PMID:27935865 NCBI chr20:33,283,214...33,309,871
Ensembl chr20:33,273,480...33,309,871 		JBrowse link
G BSG basigin (Ok blood group) multiple interactions
decreases expression		 EXP 2-chloro-5-nitrobenzanilide inhibits the reaction [pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]
pioglitazone results in decreased expression of BSG protein		 CTD PMID:16860414 PMID:17007354 PMID:17055343 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,494 		JBrowse link
G BTN2A2 butyrophilin subfamily 2 member A2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BTN2A2 mRNA CTD PMID:27935865 NCBI chr 6:26,383,108...26,394,874
Ensembl chr 6:26,383,096...26,394,874 		JBrowse link
G BZW1 basic leucine zipper and W2 domains 1 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of BZW1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BZW1 mRNA] CTD PMID:20847119 NCBI chr 2:200,811,589...200,827,338
Ensembl chr 2:200,810,594...200,827,338 		JBrowse link
G C1orf54 chromosome 1 open reading frame 54 decreases expression EXP Pioglitazone results in decreased expression of C1ORF54 mRNA CTD PMID:30031879 NCBI chr 1:150,268,731...150,280,924
Ensembl chr 1:150,268,200...150,280,916 		JBrowse link
G C1QTNF7 C1q and TNF related 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of C1QTNF7 mRNA CTD PMID:27935865 NCBI chr 4:15,339,786...15,446,167
Ensembl chr 4:15,339,818...15,446,167 		JBrowse link
G C4A complement C4A (Chido/Rodgers blood group) multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of C4A mRNA CTD PMID:27935865 NCBI chr 6:31,982,057...32,002,681
Ensembl chr 6:31,982,057...32,002,681 		JBrowse link
G C5AR1 complement C5a receptor 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of C5AR1 mRNA CTD PMID:27935865 NCBI chr19:47,307,477...47,322,066
Ensembl chr19:47,290,023...47,322,066 		JBrowse link
G CA3 carbonic anhydrase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CAR3 mRNA CTD PMID:27935865 NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040 		JBrowse link
G CABCOCO1 ciliary associated calcium binding coiled-coil 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CABCOCO1 mRNA CTD PMID:27935865 NCBI chr10:61,662,929...61,766,766
Ensembl chr10:61,662,929...61,766,766 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CACNA1C mRNA CTD PMID:27935865 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950 		JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CACNA1S mRNA CTD PMID:27935865 NCBI chr 1:201,039,512...201,112,426
Ensembl chr 1:201,039,512...201,112,451 		JBrowse link
G CACNA2D3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CACNA2D3 mRNA CTD PMID:27935865 NCBI chr 3:54,122,552...55,074,557
Ensembl chr 3:54,122,552...55,074,557 		JBrowse link
G CADM2 cell adhesion molecule 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CADM2 mRNA CTD PMID:27935865 NCBI chr 3:84,958,989...86,074,429
Ensembl chr 3:84,958,989...86,074,429 		JBrowse link
G CALHM5 calcium homeostasis modulator family member 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CALHM5 mRNA CTD PMID:27935865 NCBI chr 6:116,511,639...116,524,788
Ensembl chr 6:116,511,639...116,524,788 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO pioglitazone inhibits the reaction [Galactose results in increased activity of CASP3 protein]
[Fenofibrate co-treated with Pioglitazone] inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of CASP3 mRNA]; Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of CASP3 mRNA]		 CTD PMID:23795773 PMID:30130594 PMID:36988379 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASQ1 calsequestrin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CASQ1 mRNA CTD PMID:27935865 NCBI chr 1:160,190,575...160,201,886
Ensembl chr 1:160,190,575...160,201,886 		JBrowse link
G CAT catalase multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased activity of CAT protein]]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of CAT protein]		 CTD PMID:20450929 PMID:27350165 PMID:29233026 PMID:29247773 PMID:32735850 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CAV1 caveolin 1 affects expression EXP pioglitazone affects the expression of CAV1 protein CTD PMID:17961437 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CAV3 caveolin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CAV3 mRNA CTD PMID:27935865 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808 		JBrowse link
G CCDC159 coiled-coil domain containing 159 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCDC159 mRNA CTD PMID:27935865 NCBI chr19:11,346,519...11,354,944
Ensembl chr19:11,344,684...11,354,944 		JBrowse link
G CCDC85A coiled-coil domain containing 85A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCDC85A mRNA CTD PMID:27935865 NCBI chr 2:56,183,852...56,386,174
Ensembl chr 2:56,183,990...56,386,172 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 multiple interactions ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL11 protein] CTD PMID:17015710 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions EXP
ISO		 [Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCL2 mRNA; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL2 mRNA		 CTD PMID:20847119 PMID:27935865 PMID:32613381 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions
decreases expression		 ISO
EXP		 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL3 mRNA
Pioglitazone results in decreased expression of CCL3 mRNA		 CTD PMID:27935865 PMID:30031879 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL3L1 C-C motif chemokine ligand 3 like 1 decreases expression EXP Pioglitazone results in decreased expression of CCL3L1 mRNA CTD PMID:30031879 Ensembl chr17:36,194,869...36,196,758 JBrowse link
G CCL3L3 C-C motif chemokine ligand 3 like 3 decreases expression EXP Pioglitazone results in decreased expression of CCL3L3 mRNA CTD PMID:30031879 NCBI chr17:36,194,869...36,196,758
Ensembl chr17:36,194,869...36,196,758 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions
decreases response to substance		 ISO
EXP		 pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]
pioglitazone results in decreased susceptibility to CCL5 protein		 CTD PMID:17015710 PMID:18158351 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL7 mRNA CTD PMID:27935865 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CCN2 cellular communication network factor 2 multiple interactions EXP
ISO		 [Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCN2 mRNA; Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of CCN2 mRNA]
Pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA]		 CTD PMID:16484506 PMID:20847119 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCNA1 cyclin A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCNA1 mRNA CTD PMID:27935865 NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870 		JBrowse link
G CCNA2 cyclin A2 decreases expression EXP pioglitazone results in decreased expression of CCNA2 protein CTD PMID:15729575 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCNB1 cyclin B1 decreases expression EXP pioglitazone results in decreased expression of CCNB1 protein CTD PMID:15729575 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CCND1 cyclin D1 decreases expression
multiple interactions		 ISO
EXP		 pioglitazone results in decreased expression of CCND1 mRNA; pioglitazone results in decreased expression of CCND1 protein
pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CCND1 protein]
Pioglitazone results in decreased expression of CCND1 mRNA		 CTD PMID:17077279 PMID:26643070 PMID:30031879 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCND3 cyclin D3 decreases expression EXP pioglitazone results in decreased expression of CCND3 protein CTD PMID:15729575 NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357 		JBrowse link
G CCNE1 cyclin E1 decreases expression EXP pioglitazone results in decreased expression of CCNE1 protein CTD PMID:15729575 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312 		JBrowse link
G CCNO cyclin O multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCNO mRNA CTD PMID:27935865 NCBI chr 5:55,231,152...55,233,608
Ensembl chr 5:55,231,152...55,233,608 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) increases expression
multiple interactions		 EXP
ISO		 Pioglitazone results in increased expression of CD36 mRNA; Pioglitazone results in increased expression of CD36 protein
Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; PPARG protein affects the reaction [Pioglitazone results in increased expression of CD36 protein]
[pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of CD36 mRNA
pioglitazone results in increased expression of CD36 mRNA		 CTD PMID:15381068 PMID:16484506 PMID:17143554 PMID:19048458 PMID:20723549 More... NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CD84 CD84 molecule decreases expression EXP Pioglitazone results in decreased expression of CD84 mRNA CTD PMID:30031879 NCBI chr 1:160,541,098...160,579,496
Ensembl chr 1:160,541,095...160,579,516 		JBrowse link
G CDC20B cell division cycle 20B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CDC20B mRNA CTD PMID:27935865 NCBI chr 5:55,112,971...55,173,177
Ensembl chr 5:55,112,971...55,173,177 		JBrowse link
G CDC42 cell division cycle 42 decreases expression EXP Pioglitazone results in decreased expression of CDC42 mRNA CTD PMID:32589349 NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,052,627...22,101,360 		JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression EXP pioglitazone results in decreased expression of CDK2 protein CTD PMID:15729575 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDKL1 cyclin dependent kinase like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CDKL1 mRNA CTD PMID:27935865 NCBI chr14:50,326,265...50,397,298
Ensembl chr14:50,326,265...50,416,461 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions
decreases expression		 ISO
EXP		 pioglitazone inhibits the reaction [2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]]; pioglitazone promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]
Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]]; Pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CDKN1A protein]; Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]; Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in increased expression of CDKN1A protein]]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]
pioglitazone results in decreased expression of CDKN1A protein		 CTD PMID:15729575 PMID:17582756 PMID:26643070 PMID:29734669 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B multiple interactions
increases expression		 ISO
EXP		 pioglitazone inhibits the reaction [2-Acetylaminofluorene promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]]; pioglitazone promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]
pioglitazone results in increased expression of CDKN1B protein
pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased degradation of CDKN1B protein]; PRKAA1 protein affects the reaction [pioglitazone results in increased expression of CDKN1B protein]		 CTD PMID:17582756 PMID:26643070 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1C mRNA CTD PMID:20847119 NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha increases expression ISO pioglitazone results in increased expression of CEBPA mRNA CTD PMID:28242381 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G CEMIP cell migration inducing hyaluronidase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CEMIP mRNA CTD PMID:27935865 NCBI chr15:80,779,370...80,951,771
Ensembl chr15:80,779,343...80,951,776 		JBrowse link
G CES1 carboxylesterase 1 increases expression EXP pioglitazone results in increased expression of CES1 mRNA CTD PMID:15381068 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G CFD complement factor D multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CFD mRNA CTD PMID:27935865 NCBI chr19:859,664...863,641
Ensembl chr19:859,453...867,884 		JBrowse link
G CGB1 chorionic gonadotropin subunit beta 1 increases expression EXP Pioglitazone results in increased expression of CGB1 mRNA CTD PMID:30031879 NCBI chr19:49,035,569...49,036,895
Ensembl chr19:49,035,569...49,036,895 		JBrowse link
G CGB5 chorionic gonadotropin subunit beta 5 increases expression EXP Pioglitazone results in increased expression of CGB5 mRNA CTD PMID:30031879 NCBI chr19:49,043,848...49,045,311
Ensembl chr19:49,043,848...49,045,311 		JBrowse link
G CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 decreases expression EXP Pioglitazone results in decreased expression of CHCHD6 mRNA CTD PMID:30031879 NCBI chr 3:126,704,240...126,960,420
Ensembl chr 3:126,704,240...126,960,420 		JBrowse link
G CHI3L1 chitinase 3 like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of CHI3L1 mRNA CTD PMID:27935865 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CHIT1 chitinase 1 decreases expression EXP Pioglitazone results in decreased expression of CHIT1 mRNA CTD PMID:30031879 NCBI chr 1:203,216,079...203,230,099
Ensembl chr 1:203,212,827...203,273,641 		JBrowse link
G CHP2 calcineurin like EF-hand protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHP2 mRNA CTD PMID:27935865 NCBI chr16:23,755,026...23,758,935
Ensembl chr16:23,755,026...23,758,935 		JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRM1 mRNA CTD PMID:27935865 NCBI chr11:62,908,679...62,921,878
Ensembl chr11:62,908,679...62,921,807 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRM2 mRNA CTD PMID:27935865 NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,652...137,020,255 		JBrowse link
G CHRNA1 cholinergic receptor nicotinic alpha 1 subunit multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRNA1 mRNA CTD PMID:27935865 NCBI chr 2:174,747,592...174,764,472
Ensembl chr 2:174,747,592...174,787,935 		JBrowse link
G CHRNE cholinergic receptor nicotinic epsilon subunit multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRNE mRNA CTD PMID:27935865 NCBI chr17:4,897,771...4,908,677
Ensembl chr17:4,897,771...4,934,438 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex multiple interactions EXP [Metformin co-treated with Pioglitazone] results in decreased expression of CHUK mRNA CTD PMID:32589349 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CIDEC cell death inducing DFFA like effector c multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CIDEC mRNA CTD PMID:27935865 NCBI chr 3:9,866,710...9,880,253
Ensembl chr 3:9,866,711...9,880,255 		JBrowse link
G CKM creatine kinase, M-type multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CKM mRNA CTD PMID:27935865 NCBI chr19:45,306,413...45,322,875
Ensembl chr19:45,306,413...45,322,875 		JBrowse link
G CKMT2 creatine kinase, mitochondrial 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CKMT2 mRNA CTD PMID:27935865 NCBI chr 5:81,233,322...81,266,398
Ensembl chr 5:81,233,320...81,266,398 		JBrowse link
G CLEC14A C-type lectin domain containing 14A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CLEC14A mRNA CTD PMID:27935865 NCBI chr14:38,254,000...38,256,093
Ensembl chr14:38,254,000...38,256,093 		JBrowse link
G CLEC1A C-type lectin domain family 1 member A increases expression EXP Pioglitazone results in increased expression of CLEC1A mRNA CTD PMID:30031879 NCBI chr12:10,069,554...10,098,985
Ensembl chr12:10,069,554...10,111,627 		JBrowse link
G CLEC4A C-type lectin domain family 4 member A decreases expression EXP Pioglitazone results in decreased expression of CLEC4A mRNA CTD PMID:30031879 NCBI chr12:8,102,907...8,138,607
Ensembl chr12:8,123,617...8,138,607 		JBrowse link
G CLEC4D C-type lectin domain family 4 member D multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CLEC4D mRNA CTD PMID:27935865 NCBI chr12:8,513,503...8,531,696
Ensembl chr12:8,509,475...8,522,366 		JBrowse link
G CLEC4E C-type lectin domain family 4 member E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CLEC4E mRNA CTD PMID:27935865 NCBI chr12:8,533,275...8,540,905
Ensembl chr12:8,533,305...8,540,905 		JBrowse link
G CLSTN3 calsyntenin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CLSTN3 mRNA CTD PMID:27935865 NCBI chr12:7,129,093...7,158,945
Ensembl chr12:7,129,698...7,158,945 		JBrowse link
G CMYA5 cardiomyopathy associated 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CMYA5 mRNA CTD PMID:27935865 NCBI chr 5:79,689,836...79,800,222
Ensembl chr 5:79,689,836...79,800,240 		JBrowse link
G CNGA3 cyclic nucleotide gated channel subunit alpha 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CNGA3 mRNA CTD PMID:27935865 NCBI chr 2:98,346,456...98,398,601
Ensembl chr 2:98,346,188...98,398,601 		JBrowse link
G CNN1 calponin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CNN1 mRNA CTD PMID:27935865 NCBI chr19:11,538,851...11,550,323
Ensembl chr19:11,538,767...11,550,323 		JBrowse link
G CNRIP1 cannabinoid receptor interacting protein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CNRIP1 mRNA CTD PMID:27935865 NCBI chr 2:68,284,171...68,319,949
Ensembl chr 2:68,284,171...68,320,051 		JBrowse link
G CNTD1 cyclin N-terminal domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CNTD1 mRNA CTD PMID:27935865 NCBI chr17:42,798,785...42,811,587
Ensembl chr17:42,798,800...42,811,587 		JBrowse link
G COG8 component of oligomeric golgi complex 8 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of COG8 mRNA CTD PMID:20847119 NCBI chr16:69,326,428...69,339,564
Ensembl chr16:69,320,140...69,339,583 		JBrowse link
G COL6A5 collagen type VI alpha 5 chain multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of COL6A5 mRNA CTD PMID:27935865 NCBI chr 3:130,345,672...130,484,846
Ensembl chr 3:130,345,516...130,484,846 		JBrowse link
G CORO6 coronin 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CORO6 mRNA CTD PMID:27935865 NCBI chr17:29,614,762...29,622,912
Ensembl chr17:29,614,756...29,622,912 		JBrowse link
G COX6A2 cytochrome c oxidase subunit 6A2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of COX6A2 mRNA CTD PMID:27935865 NCBI chr16:31,427,731...31,428,360
Ensembl chr16:31,427,731...31,428,360 		JBrowse link
G COX8BP cytochrome c oxidase subunit 8B, pseudogene multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of COX8B mRNA CTD PMID:27935865 NCBI chr11:253,417...256,972
Ensembl chr11:253,446...253,558 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A multiple interactions EXP Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA] CTD PMID:32613381 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G CPT1B carnitine palmitoyltransferase 1B increases expression ISO pioglitazone results in increased expression of CPT1B mRNA CTD PMID:20723549 NCBI chr22:50,568,861...50,578,612
Ensembl chr22:50,568,861...50,578,465 		JBrowse link
G CPXM1 carboxypeptidase X, M14 family member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CPXM1 mRNA CTD PMID:27935865 NCBI chr20:2,794,074...2,800,627
Ensembl chr20:2,794,074...2,800,627 		JBrowse link
G CPZ carboxypeptidase Z multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CPZ mRNA CTD PMID:27935865 NCBI chr 4:8,592,765...8,619,752
Ensembl chr 4:8,592,660...8,619,759 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CREB1 protein] CTD PMID:32735850 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CRH corticotropin releasing hormone increases expression EXP Pioglitazone results in increased expression of CRH mRNA CTD PMID:30031879 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CRHR2 mRNA CTD PMID:27935865 NCBI chr 7:30,651,942...30,700,103
Ensembl chr 7:30,651,942...30,700,129 		JBrowse link
G CRISPLD1 cysteine rich secretory protein LCCL domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CRISPLD1 mRNA CTD PMID:27935865 NCBI chr 8:74,984,505...75,034,558
Ensembl chr 8:74,984,505...75,034,558 		JBrowse link
G CRP C-reactive protein affects expression
decreases expression		 ISO
EXP		 pioglitazone affects the expression of CRP protein
Pioglitazone results in decreased expression of CRP protein		 CTD PMID:28705172 PMID:28744220 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CRYAB crystallin alpha B multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CRYAB mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of CRYAB mRNA] CTD PMID:20847119 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722 		JBrowse link
G CRYM crystallin mu multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CRYM mRNA CTD PMID:27935865 NCBI chr16:21,258,521...21,303,062
Ensembl chr16:21,238,874...21,303,083 		JBrowse link
G CSHL1 chorionic somatomammotropin hormone like 1 increases expression EXP Pioglitazone results in increased expression of CSHL1 mRNA CTD PMID:30031879 NCBI chr17:63,909,608...63,911,258
Ensembl chr17:63,909,597...63,911,341 		JBrowse link
G CSN1S1 casein alpha s1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CSN1S1 mRNA CTD PMID:27935865 NCBI chr 4:69,931,068...69,946,574
Ensembl chr 4:69,931,068...69,946,574 		JBrowse link
G CSRP3 cysteine and glycine rich protein 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CSRP3 mRNA CTD PMID:27935865 NCBI chr11:19,182,030...19,201,983
Ensembl chr11:19,182,030...19,210,571 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CTLA4 mRNA CTD PMID:27935865 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G CTNNB1 catenin beta 1 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CTNNB1 mRNA CTD PMID:20847119 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CXCL3 mRNA CTD PMID:27935865 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 decreases response to substance
multiple interactions		 EXP
ISO		 pioglitazone results in decreased susceptibility to CXCL12 protein
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CXCL12 mRNA
pioglitazone inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein]		 CTD PMID:18158351 PMID:27935865 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CXCL2 mRNA; [pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of CXCL2 mRNA CTD PMID:27935865 PMID:28263783 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 multiple interactions EXP Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein] CTD PMID:32613381 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of CXCL5 mRNA CTD PMID:27935865 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
increases expression
decreases expression		 ISO
EXP		 [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of CXCL15 mRNA
Pioglitazone results in increased expression of CXCL8 mRNA
Pioglitazone results in decreased expression of CXCL8 mRNA		 CTD PMID:27935865 PMID:30031879 PMID:32816093 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CXCR3 mRNA CTD PMID:27935865 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CXCR4 mRNA CTD PMID:20847119 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G CYBA cytochrome b-245 alpha chain decreases expression
affects activity		 EXP
ISO		 pioglitazone results in decreased expression of CYBA mRNA
pioglitazone affects the activity of CYBA protein		 CTD PMID:11172467 PMID:21962020 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 multiple interactions
decreases expression
decreases activity		 EXP pioglitazone inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased activity of CYP17A1 protein]; pioglitazone inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased expression of CYP17A1 mRNA]
pioglitazone results in decreased expression of CYP17A1 mRNA
pioglitazone results in decreased activity of CYP17A1 protein		 CTD PMID:15072549 PMID:17138841 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 increases expression EXP
ISO		 pioglitazone results in increased expression of CYP2B6 protein
Pioglitazone results in increased expression of CYP2B10 mRNA		 CTD PMID:12642470 PMID:28541575 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 multiple interactions
increases expression
affects metabolic processing
decreases activity		 EXP Gemfibrozil inhibits the reaction [CYP2C8 protein affects the metabolism of pioglitazone]
Pioglitazone results in increased expression of CYP2C8 mRNA
pioglitazone results in decreased activity of CYP2C8 protein		 CTD PMID:12642470 PMID:15900286 PMID:31233785 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CYP2E1 mRNA CTD PMID:27935865 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYP2G1P cytochrome P450 family 2 subfamily G member 1, pseudogene multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CYP2G1 mRNA CTD PMID:27935865 NCBI chr19:40,890,826...40,900,508
Ensembl chr19:40,891,219...40,900,155
Ensembl chr19:40,891,219...40,900,155 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 affects metabolic processing
multiple interactions
decreases activity
increases expression		 EXP
ISO		 CYP3A4 protein affects the metabolism of pioglitazone
Pioglitazone inhibits the reaction [Endotoxins results in decreased expression of CYP3A2 protein]
pioglitazone results in decreased activity of CYP3A4 protein
Pioglitazone results in increased expression of CYP3A4 mRNA; Pioglitazone results in increased expression of CYP3A4 protein
[pioglitazone results in increased expression of CYP3A4 protein] which results in decreased abundance of Ethinyl Estradiol; [pioglitazone results in increased expression of CYP3A4 protein] which results in decreased abundance of Midazolam; pioglitazone results in increased expression of and results in increased activity of CYP3A4 protein		 CTD PMID:12642470 PMID:15364003 PMID:15860655 PMID:15900286 PMID:16837568 More... NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
increases expression		 ISO pioglitazone promotes the reaction [U 0126 results in increased expression of CYP7A1 mRNA]; U 0126 promotes the reaction [pioglitazone results in increased expression of CYP7A1 mRNA] CTD PMID:22593575 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G DCAF12L1 DDB1 and CUL4 associated factor 12 like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DCAF12L1 mRNA CTD PMID:27935865 NCBI chr  X:126,549,383...126,552,814
Ensembl chr  X:126,549,383...126,552,814 		JBrowse link
G DCX doublecortin multiple interactions ISO Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DCX protein] CTD PMID:32735850 NCBI chr  X:111,293,779...111,412,192
Ensembl chr  X:111,293,779...111,412,429 		JBrowse link
G DDAH1 dimethylarginine dimethylaminohydrolase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DDAH1 mRNA CTD PMID:27935865 NCBI chr 1:85,318,485...85,578,200
Ensembl chr 1:85,318,481...85,578,363 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 multiple interactions
increases expression		 EXP [Metformin co-treated with Pioglitazone] results in increased expression of DDIT4 mRNA
Pioglitazone results in increased expression of DDIT4 mRNA		 CTD PMID:32589349 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G DDIT4L DNA damage inducible transcript 4 like increases expression
multiple interactions		 EXP Pioglitazone results in increased expression of DDIT4L mRNA
[Metformin co-treated with Pioglitazone] results in increased expression of DDIT4L mRNA		 CTD PMID:32589349 NCBI chr 4:100,185,870...100,190,468
Ensembl chr 4:100,185,870...100,190,782 		JBrowse link
G DEPP1 DEPP autophagy regulator 1 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of DEPP1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of DEPP1 mRNA] CTD PMID:20847119 NCBI chr10:44,976,128...44,978,809
Ensembl chr10:44,970,981...44,978,809 		JBrowse link
G DEPTOR DEP domain containing MTOR interacting protein multiple interactions EXP [Metformin co-treated with Pioglitazone] results in decreased expression of DEPTOR mRNA CTD PMID:32589349 NCBI chr 8:119,873,722...120,050,918
Ensembl chr 8:119,873,717...120,050,918 		JBrowse link
G DERL3 derlin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DERL3 mRNA CTD PMID:27935865 NCBI chr22:23,834,503...23,839,006
Ensembl chr22:23,834,503...23,839,128 		JBrowse link
G DES desmin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DES mRNA CTD PMID:27935865 NCBI chr 2:219,418,377...219,426,734
Ensembl chr 2:219,418,377...219,426,735 		JBrowse link
G DEUP1 deuterosome assembly protein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DEUP1 mRNA CTD PMID:27935865 NCBI chr11:93,329,998...93,438,470
Ensembl chr11:93,329,971...93,438,487 		JBrowse link
G DGAT1 diacylglycerol O-acyltransferase 1 increases expression ISO pioglitazone results in increased expression of DGAT1 mRNA CTD PMID:20723549 NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 increases expression ISO pioglitazone results in increased expression of DGAT2 mRNA CTD PMID:20723549 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535 		JBrowse link
G DHRS7C dehydrogenase/reductase 7C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DHRS7C mRNA CTD PMID:27935865 NCBI chr17:9,771,438...9,791,592
Ensembl chr17:9,771,434...9,791,592 		JBrowse link
G DIO2 iodothyronine deiodinase 2 increases activity
increases expression
multiple interactions		 EXP
ISO		 pioglitazone results in increased activity of DIO2 protein
pioglitazone results in increased expression of DIO2 mRNA
PPARG protein promotes the reaction [pioglitazone results in increased activity of DIO2 protein]		 CTD PMID:19036883 NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757 		JBrowse link
G DIO3 iodothyronine deiodinase 3 decreases activity ISO pioglitazone results in decreased activity of DIO3 protein CTD PMID:19036883 NCBI chr14:101,561,495...101,563,452
Ensembl chr14:101,560,139...101,563,452 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 multiple interactions EXP pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of DLG1 mRNA] CTD PMID:20847119 NCBI chr 3:197,042,560...197,299,321
Ensembl chr 3:197,042,560...197,299,330 		JBrowse link
G DMBT1 deleted in malignant brain tumors 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DMBT1 mRNA CTD PMID:27935865 NCBI chr10:122,560,754...122,643,736
Ensembl chr10:122,560,665...122,643,736 		JBrowse link
G DNAAF2 dynein axonemal assembly factor 2 multiple interactions EXP [Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of DNAAF2 mRNA; Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of DNAAF2 mRNA] CTD PMID:20847119 NCBI chr14:49,625,174...49,635,244
Ensembl chr14:49,625,174...49,635,244 		JBrowse link
G DNAH8 dynein axonemal heavy chain 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DNAH8 mRNA CTD PMID:27935865 NCBI chr 6:38,715,311...39,030,792
Ensembl chr 6:38,715,311...39,030,792 		JBrowse link
G DNER delta/notch like EGF repeat containing multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DNER mRNA CTD PMID:27935865 NCBI chr 2:229,357,629...229,714,555
Ensembl chr 2:229,357,629...229,714,555 		JBrowse link
G DPT dermatopontin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DPT mRNA CTD PMID:27935865 NCBI chr 1:168,695,468...168,729,206
Ensembl chr 1:168,695,468...168,729,206 		JBrowse link
G DPY19L2 dpy-19 like 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DPY19L2 mRNA CTD PMID:27935865 NCBI chr12:63,558,913...63,668,805
Ensembl chr12:63,558,913...63,668,939 		JBrowse link
G DRD1 dopamine receptor D1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DRD1 mRNA CTD PMID:27935865 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182 		JBrowse link
G DUSP10 dual specificity phosphatase 10 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of DUSP10 mRNA CTD PMID:20847119 NCBI chr 1:221,701,424...221,742,089
Ensembl chr 1:221,701,424...221,742,089 		JBrowse link
G DUSP26 dual specificity phosphatase 26 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DUSP26 mRNA CTD PMID:27935865 NCBI chr 8:33,591,330...33,600,023
Ensembl chr 8:33,591,330...33,600,023 		JBrowse link
G EDDM3B epididymal protein 3B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EDDM3B mRNA CTD PMID:27935865 NCBI chr14:20,768,404...20,770,948
Ensembl chr14:20,768,404...20,770,948 		JBrowse link
G EEF1A2 eukaryotic translation elongation factor 1 alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EEF1A2 mRNA CTD PMID:27935865 NCBI chr20:63,488,014...63,499,083
Ensembl chr20:63,488,013...63,499,239 		JBrowse link
G EGF epidermal growth factor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EGF mRNA CTD PMID:27935865 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFLAM EGF like, fibronectin type III and laminin G domains multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EGFLAM mRNA CTD PMID:27935865 NCBI chr 5:38,258,559...38,465,480
Ensembl chr 5:38,258,409...38,465,480 		JBrowse link
G EIF4E eukaryotic translation initiation factor 4E multiple interactions EXP [Metformin co-treated with Pioglitazone] results in decreased expression of EIF4E mRNA CTD PMID:32589349 NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
increases expression
decreases phosphorylation		 EXP pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of EIF4EBP1 protein]
Pioglitazone results in increased expression of EIF4EBP1 mRNA
pioglitazone results in decreased phosphorylation of EIF4EBP1 protein		 CTD PMID:26643070 PMID:32589349 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365 		JBrowse link
G EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 increases expression EXP Pioglitazone results in increased expression of EIF4EBP2 mRNA CTD PMID:32589349 NCBI chr10:70,404,145...70,428,618
Ensembl chr10:70,404,145...70,428,618 		JBrowse link
G EIF5A eukaryotic translation initiation factor 5A increases expression ISO pioglitazone results in increased expression of EIF5A mRNA CTD PMID:21347706 NCBI chr17:7,306,999...7,312,463
Ensembl chr17:7,306,999...7,312,463 		JBrowse link
G ELOVL4 ELOVL fatty acid elongase 4 increases expression EXP Pioglitazone results in increased expression of ELOVL4 mRNA CTD PMID:30031879 NCBI chr 6:79,914,814...79,947,553
Ensembl chr 6:79,914,814...79,947,553 		JBrowse link
G ENO3 enolase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ENO3 mRNA CTD PMID:27935865 NCBI chr17:4,948,710...4,957,129
Ensembl chr17:4,948,092...4,957,131 		JBrowse link
G EPGN epithelial mitogen multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of EPGN mRNA CTD PMID:27935865 NCBI chr 4:74,308,470...74,316,789
Ensembl chr 4:74,308,470...74,316,789 		JBrowse link
G EPHA3 EPH receptor A3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPHA3 mRNA CTD PMID:27935865 NCBI chr 3:89,107,621...89,482,134
Ensembl chr 3:89,107,621...89,482,134 		JBrowse link
G EPHA5 EPH receptor A5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPHA5 mRNA CTD PMID:27935865 NCBI chr 4:65,319,567...65,670,489
Ensembl chr 4:65,319,563...65,670,495 		JBrowse link
G EPYC epiphycan multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPYC mRNA CTD PMID:27935865 NCBI chr12:90,963,682...91,004,972
Ensembl chr12:90,963,682...91,005,026 		JBrowse link
G ERBIN erbb2 interacting protein multiple interactions EXP pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ERBIN mRNA] CTD PMID:20847119 NCBI chr 5:65,926,575...66,082,546
Ensembl chr 5:65,883,128...66,082,546 		JBrowse link
G EREG epiregulin increases expression EXP Pioglitazone results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749 		JBrowse link
G ERVMER34-1 endogenous retrovirus group MER34 member 1, envelope increases expression EXP Pioglitazone results in increased expression of ERVMER34-1 mRNA CTD PMID:30031879 NCBI chr 4:52,742,553...52,751,425
Ensembl chr 4:52,722,618...52,751,586 		JBrowse link
G F10 coagulation factor X multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of F10 mRNA CTD PMID:27935865 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529 		JBrowse link
G FABP3 fatty acid binding protein 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FABP3 mRNA CTD PMID:27935865 NCBI chr 1:31,359,588...31,373,076
Ensembl chr 1:31,365,253...31,376,850 		JBrowse link
G FABP4 fatty acid binding protein 4 multiple interactions
increases expression		 EXP
ISO		 [pioglitazone co-treated with Tretinoin] results in increased expression of FABP4 mRNA
Pioglitazone results in increased expression of FABP4 mRNA
pioglitazone results in increased expression of FABP4 mRNA
Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]		 CTD PMID:9543393 PMID:12927809 PMID:15273253 PMID:16573735 PMID:17290005 More... NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236 		JBrowse link
G FAM13A family with sequence similarity 13 member A increases expression EXP Pioglitazone results in increased expression of FAM13A mRNA CTD PMID:30031879 NCBI chr 4:88,725,960...89,057,185
Ensembl chr 4:88,725,955...89,111,398 		JBrowse link
G FAM171B family with sequence similarity 171 member B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM171B mRNA CTD PMID:27935865 NCBI chr 2:186,694,060...186,765,959
Ensembl chr 2:186,694,060...186,765,959 		JBrowse link
G FAM184B family with sequence similarity 184 member B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM184B mRNA CTD PMID:27935865 NCBI chr 4:17,629,306...17,781,621
Ensembl chr 4:17,629,306...17,781,621 		JBrowse link
G FAM210A family with sequence similarity 210 member A multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of FAM210A mRNA CTD PMID:20847119 NCBI chr18:13,663,347...13,726,558
Ensembl chr18:13,663,347...13,726,663 		JBrowse link
G FAM240B family with sequence similarity 240 member B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM240B mRNA CTD PMID:27935865 NCBI chr 9:38,694,266...38,720,133
Ensembl chr 9:38,694,266...38,720,133 		JBrowse link
G FAM47E family with sequence similarity 47 member E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM47E mRNA CTD PMID:27935865 NCBI chr 4:76,214,040...76,283,783
Ensembl chr 4:76,214,040...76,283,783 		JBrowse link
G FAT4 FAT atypical cadherin 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAT4 mRNA CTD PMID:27935865 NCBI chr 4:125,314,955...125,492,932
Ensembl chr 4:125,314,918...125,492,932 		JBrowse link
G FBLN1 fibulin 1 increases expression EXP Pioglitazone results in increased expression of FBLN1 mRNA CTD PMID:30031879 NCBI chr22:45,502,883...45,601,135
Ensembl chr22:45,502,238...45,601,135 		JBrowse link
G FBLN7 fibulin 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBLN7 mRNA CTD PMID:27935865 NCBI chr 2:112,138,385...112,244,708
Ensembl chr 2:112,138,385...112,188,218 		JBrowse link
G FBXL16 F-box and leucine rich repeat protein 16 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBXL16 mRNA CTD PMID:27935865 NCBI chr16:692,500...705,801
Ensembl chr16:692,498...705,801 		JBrowse link
G FBXO40 F-box protein 40 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBXO40 mRNA CTD PMID:27935865 NCBI chr 3:121,593,379...121,630,295
Ensembl chr 3:121,593,379...121,630,295 		JBrowse link
G FBXO43 F-box protein 43 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBXO43 mRNA CTD PMID:27935865 NCBI chr 8:100,133,351...100,150,569
Ensembl chr 8:100,133,351...100,145,817 		JBrowse link
G FCMR Fc mu receptor increases expression EXP Pioglitazone results in increased expression of FCMR mRNA CTD PMID:30031879 NCBI chr 1:206,903,317...206,923,196
Ensembl chr 1:206,903,317...206,923,247 		JBrowse link
G FGF21 fibroblast growth factor 21 increases expression EXP
ISO		 pioglitazone results in increased expression of FGF21 mRNA CTD PMID:21720023 NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333 		JBrowse link
G FGF7 fibroblast growth factor 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FGF7 mRNA CTD PMID:27935865 NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775 		JBrowse link
G FGL1 fibrinogen like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FGL1 mRNA CTD PMID:27935865 NCBI chr 8:17,864,389...17,895,538
Ensembl chr 8:17,864,380...17,910,365 		JBrowse link
G FHL1 four and a half LIM domains 1 increases expression EXP Pioglitazone results in increased expression of FHL1 mRNA CTD PMID:30031879 NCBI chr  X:136,146,702...136,211,359
Ensembl chr  X:136,146,702...136,211,359 		JBrowse link
G FILIP1 filamin A interacting protein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FILIP1 mRNA CTD PMID:27935865 NCBI chr 6:75,291,859...75,493,800
Ensembl chr 6:75,291,859...75,493,800 		JBrowse link
G FJX1 four-jointed box kinase 1 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of FJX1 mRNA CTD PMID:20847119 NCBI chr11:35,618,460...35,620,865
Ensembl chr11:35,618,460...35,620,865 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A increases expression EXP Pioglitazone results in increased expression of FKBP1A mRNA CTD PMID:32589349 NCBI chr20:1,368,978...1,393,054
Ensembl chr20:1,368,977...1,393,164 		JBrowse link
G FKBP8 FKBP prolyl isomerase 8 increases expression EXP Pioglitazone results in increased expression of FKBP8 mRNA CTD PMID:32589349 NCBI chr19:18,531,763...18,543,573
Ensembl chr19:18,531,751...18,544,077 		JBrowse link
G FLNC filamin C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FLNC mRNA CTD PMID:27935865 NCBI chr 7:128,830,406...128,859,272
Ensembl chr 7:128,830,406...128,859,274 		JBrowse link
G FNDC5 fibronectin type III domain containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FNDC5 mRNA CTD PMID:27935865 NCBI chr 1:32,862,268...32,872,484
Ensembl chr 1:32,862,268...32,872,482 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO pioglitazone results in increased expression of FOS mRNA CTD PMID:11687581 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of FOSB mRNA CTD PMID:27935865 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of FOSL1 mRNA CTD PMID:27935865 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573 		JBrowse link
G FOXN4 forkhead box N4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FOXN4 mRNA CTD PMID:27935865 NCBI chr12:109,277,978...109,309,284
Ensembl chr12:109,277,978...109,309,284 		JBrowse link
G FPR1 formyl peptide receptor 1 decreases expression EXP Pioglitazone results in decreased expression of FPR1 mRNA CTD PMID:30031879 NCBI chr19:51,745,172...51,751,878
Ensembl chr19:51,745,172...51,804,115 		JBrowse link
G FRZB frizzled related protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FRZB mRNA CTD PMID:27935865 NCBI chr 2:182,833,275...182,866,637
Ensembl chr 2:182,833,275...182,866,637 		JBrowse link
G FSCN1 fascin actin-bundling protein 1 decreases expression EXP Pioglitazone results in decreased expression of FSCN1 mRNA CTD PMID:30031879 NCBI chr 7:5,592,816...5,606,655
Ensembl chr 7:5,592,816...5,606,655 		JBrowse link
G FSD2 fibronectin type III and SPRY domain containing 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FSD2 mRNA CTD PMID:27935865 NCBI chr15:82,755,362...82,806,069
Ensembl chr15:82,755,362...82,806,070 		JBrowse link
G FXYD1 FXYD domain containing ion transport regulator 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FXYD1 mRNA CTD PMID:27935865 NCBI chr19:35,137,188...35,143,109
Ensembl chr19:35,138,824...35,143,109 		JBrowse link
G GABRA3 gamma-aminobutyric acid type A receptor subunit alpha3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GABRA3 mRNA CTD PMID:27935865 NCBI chr  X:152,166,234...152,451,315
Ensembl chr  X:152,166,234...152,451,315 		JBrowse link
G GABRA4 gamma-aminobutyric acid type A receptor subunit alpha4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GABRA4 mRNA CTD PMID:27935865 NCBI chr 4:46,918,900...46,993,581
Ensembl chr 4:46,918,900...46,993,581 		JBrowse link
G GALNT16 polypeptide N-acetylgalactosaminyltransferase 16 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GALNT16 mRNA CTD PMID:27935865 NCBI chr14:69,259,631...69,386,337
Ensembl chr14:69,259,277...69,357,033 		JBrowse link
G GALNT17 polypeptide N-acetylgalactosaminyltransferase 17 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of GALNT17 mRNA CTD PMID:27935865 NCBI chr 7:71,132,144...71,713,599
Ensembl chr 7:71,132,144...71,713,600 		JBrowse link
G GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GALNT9 mRNA CTD PMID:27935865 NCBI chr12:132,196,372...132,329,589
Ensembl chr12:132,196,372...132,329,589 		JBrowse link
G GDF15 growth differentiation factor 15 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GDF15 mRNA CTD PMID:27935865 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176 		JBrowse link
G GEM GTP binding protein overexpressed in skeletal muscle multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of GEM mRNA CTD PMID:20847119 NCBI chr 8:94,249,253...94,262,319
Ensembl chr 8:94,249,253...94,262,350 		JBrowse link
G GEMIN4 gem nuclear organelle associated protein 4 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of GEMIN4 mRNA CTD PMID:20847119 NCBI chr17:744,421...754,410
Ensembl chr17:744,421...753,999 		JBrowse link
G GFRA1 GDNF family receptor alpha 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GFRA1 mRNA CTD PMID:27935865 NCBI chr10:116,056,925...116,274,705
Ensembl chr10:116,056,925...116,276,803 		JBrowse link
G GH1 growth hormone 1 increases expression EXP Pioglitazone results in increased expression of GH1 mRNA CTD PMID:30031879 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839 		JBrowse link
G GIMAP4 GTPase, IMAP family member 4 decreases expression EXP Pioglitazone results in decreased expression of GIMAP4 mRNA CTD PMID:30031879 NCBI chr 7:150,567,390...150,573,953
Ensembl chr 7:150,567,369...150,573,953 		JBrowse link
G GLDN gliomedin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GLDN mRNA CTD PMID:27935865 NCBI chr15:51,341,655...51,413,365
Ensembl chr15:51,341,655...51,408,005 		JBrowse link
G GLYCAM1 glycosylation dependent cell adhesion molecule 1 (pseudogene) multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GLYCAM1 mRNA CTD PMID:27935865 NCBI chr12:54,608,187...54,610,462
Ensembl chr12:54,608,187...54,610,462
Ensembl chr12:54,608,187...54,610,462 		JBrowse link
G GMNC geminin coiled-coil domain containing multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GMNC mRNA CTD PMID:27935865 NCBI chr 3:190,843,271...190,862,694
Ensembl chr 3:190,852,737...190,892,429 		JBrowse link
G GNAT3 G protein subunit alpha transducin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GNAT3 mRNA CTD PMID:27935865 NCBI chr 7:80,458,635...80,512,064
Ensembl chr 7:80,458,635...80,512,064 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of GOT1 protein] CTD PMID:15318101 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624 		JBrowse link
G GOT1L1 glutamic-oxaloacetic transaminase 1 like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GOT1L1 mRNA CTD PMID:27935865 NCBI chr 8:37,934,281...37,940,124
Ensembl chr 8:37,934,281...37,940,124 		JBrowse link
G GP2 glycoprotein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GP2 mRNA CTD PMID:27935865 NCBI chr16:20,309,574...20,327,513
Ensembl chr16:20,309,574...20,327,808 		JBrowse link
G GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GPIHBP1 mRNA CTD PMID:27935865 NCBI chr 8:143,213,218...143,217,170
Ensembl chr 8:143,213,218...143,217,170 		JBrowse link
G GPM6A glycoprotein M6A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GPM6A mRNA CTD PMID:27935865 NCBI chr 4:175,632,937...176,002,691
Ensembl chr 4:175,632,934...176,002,664 		JBrowse link
G GPR183 G protein-coupled receptor 183 decreases expression EXP Pioglitazone results in decreased expression of GPR183 mRNA CTD PMID:30031879 NCBI chr13:99,294,539...99,307,399
Ensembl chr13:99,294,539...99,307,399 		JBrowse link
G GPR84 G protein-coupled receptor 84 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GPR84 mRNA CTD PMID:27935865 NCBI chr12:54,350,698...54,364,486
Ensembl chr12:54,362,445...54,364,487 		JBrowse link
G GPRASP2 G protein-coupled receptor associated sorting protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GPRASP2 mRNA CTD PMID:27935865 NCBI chr  X:102,712,448...102,717,733
Ensembl chr  X:102,712,445...102,717,733 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of GPT protein]; pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein] CTD PMID:15318101 PMID:27350165 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GPX3 glutathione peroxidase 3 increases expression EXP Pioglitazone results in increased expression of GPX3 mRNA CTD PMID:30031879 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GRM4 glutamate metabotropic receptor 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GRM4 mRNA CTD PMID:27935865 NCBI chr 6:34,018,643...34,155,622
Ensembl chr 6:34,018,643...34,155,622 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta increases expression EXP Pioglitazone results in increased expression of GSK3B mRNA CTD PMID:32589349 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSTA2 glutathione S-transferase alpha 2 multiple interactions ISO [pioglitazone co-treated with alitretinoin] results in increased expression of GSTA2 protein CTD PMID:15150131 NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 multiple interactions ISO pioglitazone inhibits the reaction [Diethylnitrosamine results in increased expression of GSTP1 protein] CTD PMID:15526359 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GSTT1 mRNA CTD PMID:27935865
G GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GUCY1A1 mRNA CTD PMID:27935865 NCBI chr 4:155,666,848...155,737,059
Ensembl chr 4:155,666,726...155,737,059 		JBrowse link
G HBB hemoglobin subunit beta multiple interactions ISO Pioglitazone inhibits the reaction [Fructose promotes the reaction [Glucose binds to HBB protein]] CTD PMID:25679220 NCBI chr11:5,225,464...5,227,071
Ensembl chr11:5,225,464...5,229,395 		JBrowse link
G HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HECW1 mRNA CTD PMID:27935865 NCBI chr 7:43,112,647...43,566,001
Ensembl chr 7:43,112,629...43,566,001 		JBrowse link
G HHATL hedgehog acyltransferase like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HHATL mRNA CTD PMID:27935865 NCBI chr 3:42,692,663...42,702,798
Ensembl chr 3:42,692,663...42,702,824 		JBrowse link
G HHIP hedgehog interacting protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HHIP mRNA CTD PMID:27935865 NCBI chr 4:144,646,156...144,745,271
Ensembl chr 4:144,646,156...144,745,271 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha decreases expression
multiple interactions		 EXP Pioglitazone results in decreased expression of HIF1A mRNA
[Metformin co-treated with Pioglitazone] results in decreased expression of HIF1A mRNA		 CTD PMID:32589349 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HIF3A hypoxia inducible factor 3 subunit alpha decreases expression ISO pioglitazone results in decreased expression of HIF3A mRNA CTD PMID:22456468 NCBI chr19:46,297,042...46,343,433
Ensembl chr19:46,297,042...46,343,433 		JBrowse link
G HILPDA hypoxia inducible lipid droplet associated multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of HILPDA mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of HILPDA mRNA] CTD PMID:20847119 NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418 		JBrowse link
G HJV hemojuvelin BMP co-receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of HJV mRNA CTD PMID:27935865 NCBI chr 1:146,017,470...146,021,735
Ensembl chr 1:146,017,468...146,036,746 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase increases expression
decreases expression		 EXP
ISO		 pioglitazone results in increased expression of HMGCR mRNA
pioglitazone results in decreased expression of HMGCR mRNA		 CTD PMID:12044893 PMID:20503262 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP pioglitazone results in increased expression of HMGCS1 mRNA CTD PMID:12044893 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression
multiple interactions		 ISO
EXP		 pioglitazone results in increased expression of HMOX1 mRNA
Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of HMOX1 mRNA]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA]
[pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA		 CTD PMID:16597547 PMID:28263783 PMID:30965670 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNRNPDL heterogeneous nuclear ribonucleoprotein D like multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of HNRNPDL mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of HNRNPDL mRNA] CTD PMID:20847119 NCBI chr 4:82,422,564...82,430,462
Ensembl chr 4:82,422,565...82,430,462 		JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase multiple interactions EXP [pioglitazone co-treated with NAD] binds to HPGD protein CTD PMID:25526675 NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154 		JBrowse link
G HPSE2 heparanase 2 (inactive) multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HPSE2 mRNA CTD PMID:27935865 NCBI chr10:98,457,077...99,315,951
Ensembl chr10:98,457,077...99,235,862 		JBrowse link
G HRC histidine rich calcium binding protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HRC mRNA CTD PMID:27935865 NCBI chr19:49,151,198...49,155,396
Ensembl chr19:49,151,198...49,155,396 		JBrowse link
G HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 decreases expression
decreases activity		 EXP pioglitazone results in decreased expression of HSD3B2 mRNA
pioglitazone results in decreased activity of HSD3B2 protein		 CTD PMID:15072549 PMID:17138841 NCBI chr 1:119,414,931...119,423,034
Ensembl chr 1:119,414,931...119,423,035 		JBrowse link
G HSPA12B heat shock protein family A (Hsp70) member 12B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HSPA12B mRNA CTD PMID:27935865 NCBI chr20:3,732,685...3,753,111
Ensembl chr20:3,732,685...3,753,111 		JBrowse link
G HSPA1L heat shock protein family A (Hsp70) member 1 like multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of HSPA1L mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of HSPA1L mRNA] CTD PMID:20847119 NCBI chr 6:31,809,619...31,815,283
Ensembl chr 6:31,809,619...31,815,283 		JBrowse link
G HSPB7 heat shock protein family B (small) member 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HSPB7 mRNA CTD PMID:27935865 NCBI chr 1:16,014,029...16,019,594
Ensembl chr 1:16,014,028...16,019,594 		JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of HTR2B mRNA CTD PMID:27935865 NCBI chr 2:231,108,230...231,125,042
Ensembl chr 2:231,108,230...231,125,042 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of ICAM1 protein] CTD PMID:17015710 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ICAM3 intercellular adhesion molecule 3 multiple interactions EXP pioglitazone inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein] CTD PMID:18158351 NCBI chr19:10,333,776...10,339,624
Ensembl chr19:10,333,776...10,339,661 		JBrowse link
G ID2 inhibitor of DNA binding 2 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ID2 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ID2 mRNA] CTD PMID:20847119 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461 		JBrowse link
G IFNG interferon gamma multiple interactions EXP pioglitazone inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]; pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of and results in increased activity of BACE1 protein]; pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased metabolism of and results in increased secretion of APP protein alternative form] CTD PMID:14586007 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions
decreases expression		 EXP [Metformin co-treated with Pioglitazone] results in decreased expression of IGF1 mRNA
Pioglitazone results in decreased expression of IGF1 mRNA		 CTD PMID:32589349 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGSF10 immunoglobulin superfamily member 10 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of IGSF10 mRNA CTD PMID:27935865 NCBI chr 3:151,432,432...151,619,925
Ensembl chr 3:151,425,384...151,461,061 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta decreases expression EXP Pioglitazone results in decreased expression of IKBKB mRNA CTD PMID:32589349 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL10 interleukin 10 multiple interactions
increases expression		 ISO Pioglitazone inhibits the reaction [propionic acid results in decreased expression of IL10 protein]
Pioglitazone results in increased expression of IL10 protein		 CTD PMID:27918843 PMID:31348919 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13 interleukin 13 multiple interactions ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL13 protein] CTD PMID:17015710 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL18 interleukin 18 multiple interactions ISO pioglitazone inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha increases expression EXP Pioglitazone results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases expression
affects expression		 EXP
ISO		 Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]
[naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of IL1B mRNA]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]]; Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; Pioglitazone inhibits the reaction [Fructose results in increased secretion of IL1B protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of IL1B mRNA]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]]
Pioglitazone results in increased expression of IL1B mRNA
[pioglitazone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA
pioglitazone affects the expression of IL1B mRNA		 CTD PMID:14586007 PMID:25679220 PMID:28138970 PMID:30031879 PMID:30130594 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL23A interleukin 23 subunit alpha multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of IL23A mRNA CTD PMID:27935865 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IL24 interleukin 24 multiple interactions
increases expression		 ISO
EXP		 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of IL24 mRNA
Pioglitazone results in increased expression of IL24 mRNA		 CTD PMID:27935865 PMID:32816093 NCBI chr 1:206,897,443...206,904,139
Ensembl chr 1:206,897,443...206,904,139 		JBrowse link
G IL4 interleukin 4 multiple interactions ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL4 protein] CTD PMID:17015710 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL5 interleukin 5 multiple interactions ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein] CTD PMID:17015710 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases expression
affects expression		 ISO [Pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of IL6 mRNA; [Sodium Glutamate co-treated with Pioglitazone] results in decreased expression of IL6 protein; Pioglitazone inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of IL6 mRNA]; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased expression of IL6 mRNA]; Pioglitazone promotes the reaction [Plant Extracts results in increased expression of IL6 protein]
Pioglitazone results in increased expression of IL6 protein
[naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of IL6 mRNA]; Pioglitazone inhibits the reaction [propionic acid results in increased expression of IL6 protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of IL6 mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of IL6 protein]
pioglitazone affects the expression of IL6 protein		 CTD PMID:18513333 PMID:27918843 PMID:28263783 PMID:28744220 PMID:29233026 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ILK integrin linked kinase decreases expression EXP Pioglitazone results in decreased expression of ILK mRNA CTD PMID:32589349 NCBI chr11:6,603,774...6,610,870
Ensembl chr11:6,603,708...6,610,874 		JBrowse link
G INMT indolethylamine N-methyltransferase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of INMT mRNA CTD PMID:27935865 NCBI chr 7:30,752,135...30,757,602
Ensembl chr 7:30,697,985...30,757,602 		JBrowse link
G INS insulin multiple interactions EXP
ISO		 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; [Dexamethasone co-treated with INS protein co-treated with Pioglitazone] results in increased expression of PPARG protein; octocrylene inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; T 0070907 inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]
[Dexamethasone co-treated with INS protein co-treated with Pioglitazone] results in increased expression of PPARG protein; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]		 CTD PMID:15273253 PMID:17290005 PMID:31016361 PMID:32473317 PMID:32613381 More... NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions
decreases secretion
affects expression		 EXP
ISO		 Pioglitazone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]
Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of INS1 protein]
Pioglitazone promotes the reaction [INS1 protein results in increased uptake of Glucose]
Pioglitazone results in decreased secretion of INS1 protein
Pioglitazone affects the expression of INS1 protein		 CTD PMID:14532171 PMID:19208898 PMID:27350165 PMID:28242381 PMID:29233026 More... NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G INSYN2B inhibitory synaptic factor family member 2B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of INSYN2B mRNA CTD PMID:27935865 NCBI chr 5:169,861,303...169,980,495
Ensembl chr 5:169,861,303...169,980,495 		JBrowse link
G IQCH IQ motif containing H multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of IQCH mRNA CTD PMID:27935865 NCBI chr15:67,254,786...67,501,804
Ensembl chr15:67,254,786...67,502,260 		JBrowse link
G IRAG1 inositol 1,4,5-triphosphate receptor associated 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of IRAG1 mRNA CTD PMID:27935865 NCBI chr11:10,573,095...10,693,755
Ensembl chr11:10,573,091...10,693,988 		JBrowse link
G ISL1 ISL LIM homeobox 1 increases expression EXP Pioglitazone results in increased expression of ISL1 mRNA CTD PMID:30031879 NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730 		JBrowse link
G ISM2 isthmin 2 increases expression EXP Pioglitazone results in increased expression of ISM2 mRNA CTD PMID:30031879 NCBI chr14:77,474,394...77,498,816
Ensembl chr14:77,474,394...77,498,816 		JBrowse link
G ITGA8 integrin subunit alpha 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ITGA8 mRNA CTD PMID:27935865 NCBI chr10:15,513,954...15,719,922
Ensembl chr10:15,513,954...15,719,922 		JBrowse link
G ITGAV integrin subunit alpha V multiple interactions EXP pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ITGAV mRNA] CTD PMID:20847119 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,010...186,680,901 		JBrowse link
G ITGB1BP2 integrin subunit beta 1 binding protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ITGB1BP2 mRNA CTD PMID:27935865 NCBI chr  X:71,301,750...71,305,371
Ensembl chr  X:71,301,750...71,305,371 		JBrowse link
G ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ITIH2 mRNA CTD PMID:27935865 NCBI chr10:7,703,316...7,749,520
Ensembl chr10:7,703,316...7,749,520 		JBrowse link
G ITLN1 intelectin 1 increases expression EXP pioglitazone results in increased expression of ITLN1 protein CTD PMID:23555749 NCBI chr 1:160,876,540...160,885,180
Ensembl chr 1:160,876,540...160,885,180 		JBrowse link
G JCHAIN joining chain of multimeric IgA and IgM multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of JCHAIN mRNA CTD PMID:27935865 NCBI chr 4:70,655,541...70,666,508
Ensembl chr 4:70,655,541...70,681,817 		JBrowse link
G JPH2 junctophilin 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of JPH2 mRNA CTD PMID:27935865 NCBI chr20:44,106,590...44,187,188
Ensembl chr20:44,106,590...44,187,188 		JBrowse link
G KANK4 KN motif and ankyrin repeat domains 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KANK4 mRNA CTD PMID:27935865 NCBI chr 1:62,236,165...62,319,434
Ensembl chr 1:62,236,165...62,319,434 		JBrowse link
G KCNB1 potassium voltage-gated channel subfamily B member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCNB1 mRNA CTD PMID:27935865 NCBI chr20:49,363,877...49,483,362
Ensembl chr20:49,293,394...49,484,297 		JBrowse link
G KCNC4 potassium voltage-gated channel subfamily C member 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCNC4 mRNA CTD PMID:27935865 NCBI chr 1:110,210,314...110,284,080
Ensembl chr 1:110,210,314...110,283,100 		JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCND3 mRNA CTD PMID:27935865 NCBI chr 1:111,770,662...111,989,668
Ensembl chr 1:111,770,662...111,989,668 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCNJ11 mRNA CTD PMID:27935865 NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331 		JBrowse link
G KCNJ13 potassium inwardly rectifying channel subfamily J member 13 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCNJ13 mRNA CTD PMID:27935865 NCBI chr 2:232,765,802...232,776,565
Ensembl chr 2:232,765,802...232,776,565 		JBrowse link
G KLF2 KLF transcription factor 2 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of KLF2 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of KLF2 mRNA] CTD PMID:20847119 NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685 		JBrowse link
G KLF5 KLF transcription factor 5 multiple interactions ISO pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 mRNA]; pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 protein] CTD PMID:25874449 NCBI chr13:73,054,976...73,077,538
Ensembl chr13:73,054,976...73,077,541 		JBrowse link
G KLHL13 kelch like family member 13 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KLHL13 mRNA CTD PMID:27935865 NCBI chr  X:117,897,813...118,117,340
Ensembl chr  X:117,897,813...118,117,340 		JBrowse link
G KLHL31 kelch like family member 31 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KLHL31 mRNA CTD PMID:27935865 NCBI chr 6:53,647,916...53,665,756
Ensembl chr 6:53,647,916...53,665,756 		JBrowse link
G KLHL40 kelch like family member 40 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KLHL40 mRNA CTD PMID:27935865 NCBI chr 3:42,685,537...42,692,544
Ensembl chr 3:42,685,537...42,692,544 		JBrowse link
G KLHL41 kelch like family member 41 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KLHL41 mRNA CTD PMID:27935865 NCBI chr 2:169,509,702...169,526,258
Ensembl chr 2:169,509,702...169,526,258 		JBrowse link
G KLK6 kallikrein related peptidase 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KLK6 mRNA CTD PMID:27935865 NCBI chr19:50,958,631...50,969,591
Ensembl chr19:50,958,631...50,969,673 		JBrowse link
G KRT16 keratin 16 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KRT16 mRNA CTD PMID:27935865 NCBI chr17:41,609,778...41,612,767
Ensembl chr17:41,609,778...41,615,899 		JBrowse link
G KRT20 keratin 20 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KRT20 mRNA CTD PMID:27935865 NCBI chr17:40,875,889...40,885,242
Ensembl chr17:40,875,889...40,885,242 		JBrowse link
G KRT6A keratin 6A decreases expression EXP Pioglitazone results in decreased expression of KRT6A mRNA CTD PMID:30031879 NCBI chr12:52,487,176...52,493,257
Ensembl chr12:52,487,176...52,493,257 		JBrowse link
G KRT6B keratin 6B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of KRT6B mRNA CTD PMID:27935865 NCBI chr12:52,446,651...52,452,146
Ensembl chr12:52,446,651...52,452,146 		JBrowse link
G KRT84 keratin 84 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KRT84 mRNA CTD PMID:27935865 NCBI chr12:52,377,812...52,386,977
Ensembl chr12:52,377,812...52,385,652 		JBrowse link
G KRT90P keratin 90, pseudogene multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KRT90 mRNA CTD PMID:27935865 NCBI chr12:52,413,861...52,419,240
Ensembl chr12:52,411,742...52,421,867 		JBrowse link
G KY kyphoscoliosis peptidase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KY mRNA CTD PMID:27935865 NCBI chr 3:134,599,923...134,651,022
Ensembl chr 3:134,599,923...134,651,636 		JBrowse link
G LAMA2 laminin subunit alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LAMA2 mRNA CTD PMID:27935865 NCBI chr 6:128,883,138...129,516,566
Ensembl chr 6:128,883,138...129,516,566 		JBrowse link
G LARP6 La ribonucleoprotein 6, translational regulator multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LARP6 mRNA CTD PMID:27935865 NCBI chr15:70,829,130...70,854,157
Ensembl chr15:70,829,130...70,854,157 		JBrowse link
G LCE1F late cornified envelope 1F multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of LCE1F mRNA CTD PMID:27935865 NCBI chr 1:152,775,140...152,777,024
Ensembl chr 1:152,775,140...152,777,024 		JBrowse link
G LDLR low density lipoprotein receptor increases expression
multiple interactions		 ISO pioglitazone results in increased expression of LDLR protein
[pioglitazone co-treated with U 0126] affects the localization of LDLR protein		 CTD PMID:22593575 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G LEP leptin increases expression ISO pioglitazone results in increased expression of LEP protein CTD PMID:15655531 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LEPR leptin receptor increases response to substance
multiple interactions		 ISO LEPR gene mutant form results in increased susceptibility to Pioglitazone
Pioglitazone inhibits the reaction [LEPR protein affects the expression of OGG1 protein]; Pioglitazone inhibits the reaction [LEPR protein affects the expression of XRCC1 protein]		 CTD PMID:29743445 PMID:35472412 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G LGI1 leucine rich glioma inactivated 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LGI1 mRNA CTD PMID:27935865 NCBI chr10:93,757,936...93,798,159
Ensembl chr10:93,757,840...93,806,272 		JBrowse link
G LHFPL4 LHFPL tetraspan subfamily member 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LHFPL4 mRNA CTD PMID:27935865 NCBI chr 3:9,498,361...9,553,822
Ensembl chr 3:9,498,361...9,553,822 		JBrowse link
G LILRA2 leukocyte immunoglobulin like receptor A2 decreases expression EXP Pioglitazone results in decreased expression of LILRA2 mRNA CTD PMID:30031879 NCBI chr19:54,572,988...54,590,287
Ensembl chr19:54,572,920...54,590,287 		JBrowse link
G LIPC lipase C, hepatic type increases expression ISO pioglitazone results in increased expression of LIPC mRNA CTD PMID:20503262 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G LIPF lipase F, gastric type multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LIPF mRNA CTD PMID:27935865 NCBI chr10:88,664,442...88,678,814
Ensembl chr10:88,664,441...88,678,814 		JBrowse link
G LIPN lipase family member N multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of LIPN mRNA CTD PMID:27935865 NCBI chr10:88,757,226...88,779,626
Ensembl chr10:88,759,982...88,779,626 		JBrowse link
G LITAF lipopolysaccharide induced TNF factor multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of LITAF mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of LITAF mRNA] CTD PMID:20847119 NCBI chr16:11,547,722...11,640,317
Ensembl chr16:11,547,722...11,636,381 		JBrowse link
G LMAN1L lectin, mannose binding 1 like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LMAN1L mRNA CTD PMID:27935865 NCBI chr15:74,812,835...74,825,754
Ensembl chr15:74,812,716...74,825,757 		JBrowse link
G LMOD3 leiomodin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LMOD3 mRNA CTD PMID:27935865 NCBI chr 3:69,106,065...69,122,595
Ensembl chr 3:69,106,065...69,123,032 		JBrowse link
G LRRC39 leucine rich repeat containing 39 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LRRC39 mRNA CTD PMID:27935865 NCBI chr 1:100,148,448...100,179,667
Ensembl chr 1:100,148,448...100,178,267 		JBrowse link
G LRRC3B leucine rich repeat containing 3B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LRRC3B mRNA CTD PMID:27935865 NCBI chr 3:26,622,772...26,710,776
Ensembl chr 3:26,622,772...26,717,537 		JBrowse link
G LRRN1 leucine rich repeat neuronal 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LRRN1 mRNA CTD PMID:27935865 NCBI chr 3:3,799,431...3,849,834
Ensembl chr 3:3,799,431...3,849,834 		JBrowse link
G LRRN3 leucine rich repeat neuronal 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LRRN3 mRNA CTD PMID:27935865 NCBI chr 7:111,091,127...111,125,454
Ensembl chr 7:111,091,006...111,125,454 		JBrowse link
G MAGIX MAGI family member, X-linked multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MAGIX mRNA CTD PMID:27935865 NCBI chr  X:49,162,665...49,168,774
Ensembl chr  X:49,162,564...49,168,774 		JBrowse link
G MAOB monoamine oxidase B multiple interactions EXP pioglitazone binds to and results in decreased activity of MAOB protein CTD PMID:22282722 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation		 ISO
EXP		 pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 protein]; pioglitazone results in increased phosphorylation of and results in increased activity of MAPK1 protein
pioglitazone results in decreased phosphorylation of MAPK1 protein
[PDGFB protein binds to PDGFB protein] inhibits the reaction [pioglitazone results in decreased phosphorylation of MAPK1 protein]		 CTD PMID:11687581 PMID:17063547 PMID:26643070 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation		 ISO
EXP		 pioglitazone results in increased phosphorylation of and results in increased activity of MAPK3 protein
[PDGFB protein binds to PDGFB protein] inhibits the reaction [pioglitazone results in decreased phosphorylation of MAPK3 protein]		 CTD PMID:11687581 PMID:26643070 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MB myoglobin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MB mRNA CTD PMID:27935865 NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951 		JBrowse link
G MB21D2 Mab-21 domain containing 2 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of MB21D2 mRNA CTD PMID:20847119 NCBI chr 3:192,796,815...192,917,856
Ensembl chr 3:192,796,815...192,917,856 		JBrowse link
G MCEMP1 mast cell expressed membrane protein 1 increases expression EXP Pioglitazone results in increased expression of MCEMP1 mRNA CTD PMID:30031879 NCBI chr19:7,677,090...7,679,829
Ensembl chr19:7,677,088...7,679,829 		JBrowse link
G MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MCIDAS mRNA CTD PMID:27935865 NCBI chr 5:55,219,564...55,227,315
Ensembl chr 5:55,219,564...55,227,315 		JBrowse link
G MEF2C myocyte enhancer factor 2C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MEF2C mRNA CTD PMID:27935865 NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase increases expression EXP Pioglitazone results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G METTL21EP methyltransferase like 21E, pseudogene multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of METTL21E mRNA CTD PMID:27935865 NCBI chr13:102,880,099...102,896,033
Ensembl chr13:102,880,040...102,896,033 		JBrowse link
G MFAP4 microfibril associated protein 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MFAP4 mRNA CTD PMID:27935865 NCBI chr17:19,383,445...19,387,190
Ensembl chr17:19,383,442...19,387,190 		JBrowse link
G MGAM maltase-glucoamylase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MGAM mRNA CTD PMID:27935865 NCBI chr 7:141,986,518...142,106,747
Ensembl chr 7:141,907,813...142,106,747 		JBrowse link
G MIR133B microRNA 133b multiple interactions ISO [Pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of MIR133B mRNA CTD PMID:28263783 NCBI chr 6:52,148,923...52,149,041
Ensembl chr 6:52,148,923...52,149,041 		JBrowse link
G MIR206 microRNA 206 multiple interactions ISO [Pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of MIR206 mRNA CTD PMID:28263783 NCBI chr 6:52,144,349...52,144,434
Ensembl chr 6:52,144,349...52,144,434 		JBrowse link
G MLIP muscular LMNA interacting protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MLIP mRNA CTD PMID:27935865 NCBI chr 6:54,018,970...54,266,280
Ensembl chr 6:53,929,982...54,266,280 		JBrowse link
G MME membrane metalloendopeptidase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MME mRNA CTD PMID:27935865 NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704 		JBrowse link
G MMP12 matrix metallopeptidase 12 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MMP12 mRNA CTD PMID:27935865 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G MMP13 matrix metallopeptidase 13 multiple interactions ISO pioglitazone affects the reaction [Carbon Tetrachloride results in increased cleavage of MMP13 protein] CTD PMID:16484506 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
G MMP7 matrix metallopeptidase 7 multiple interactions
decreases expression		 ISO
EXP		 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MMP7 mRNA
Pioglitazone results in decreased expression of MMP7 mRNA		 CTD PMID:27935865 PMID:30031879 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750 		JBrowse link
G MMP8 matrix metallopeptidase 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MMP8 mRNA CTD PMID:27935865 NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions
decreases expression
decreases secretion		 EXP 2-chloro-5-nitrobenzanilide inhibits the reaction [pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]
Pioglitazone results in decreased expression of MMP9 mRNA
pioglitazone results in decreased secretion of MMP9 protein		 CTD PMID:16860414 PMID:17055343 PMID:30031879 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MS4A7 membrane spanning 4-domains A7 increases expression EXP Pioglitazone results in increased expression of MS4A7 mRNA CTD PMID:30031879 NCBI chr11:60,378,532...60,395,948
Ensembl chr11:60,378,485...60,395,951 		JBrowse link
G MSTN myostatin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MSTN mRNA CTD PMID:27935865 NCBI chr 2:190,055,700...190,062,729
Ensembl chr 2:190,055,700...190,062,729 		JBrowse link
G MTARC1 mitochondrial amidoxime reducing component 1 increases expression EXP Pioglitazone results in increased expression of MTARC1 mRNA CTD PMID:30031879 NCBI chr 1:220,786,913...220,819,659
Ensembl chr 1:220,786,352...220,819,659 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions EXP [Metformin co-treated with Pioglitazone] results in decreased expression of MTOR mRNA CTD PMID:32589349 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MUC1 mucin 1, cell surface associated decreases expression EXP Pioglitazone results in decreased expression of MUC1 mRNA CTD PMID:30031879 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G MUC5B mucin 5B, oligomeric mucus/gel-forming multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MUC5B mRNA CTD PMID:27935865 NCBI chr11:1,223,066...1,262,172
Ensembl chr11:1,223,066...1,262,172 		JBrowse link
G MUCL3 mucin like 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MUCL3 mRNA CTD PMID:27935865 NCBI chr 6:30,940,973...30,954,221
Ensembl chr 6:30,934,523...30,954,221 		JBrowse link
G MXD1 MAX dimerization protein 1 multiple interactions EXP [Pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of MXD1 mRNA; Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of MXD1 mRNA] CTD PMID:20847119 NCBI chr 2:69,915,109...69,942,945
Ensembl chr 2:69,897,688...69,942,945 		JBrowse link
G MYBPC1 myosin binding protein C1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYBPC1 mRNA CTD PMID:27935865 NCBI chr12:101,594,971...101,695,841
Ensembl chr12:101,568,353...101,686,028 		JBrowse link
G MYF6 myogenic factor 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYF6 mRNA CTD PMID:27935865 NCBI chr12:80,707,634...80,709,474
Ensembl chr12:80,707,634...80,709,474 		JBrowse link
G MYH1 myosin heavy chain 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH1 mRNA CTD PMID:27935865 NCBI chr17:10,492,307...10,518,542
Ensembl chr17:10,492,307...10,518,542 		JBrowse link
G MYH11 myosin heavy chain 11 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH11 mRNA CTD PMID:27935865 NCBI chr16:15,703,135...15,857,028
Ensembl chr16:15,703,135...15,857,028 		JBrowse link
G MYH13 myosin heavy chain 13 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH13 mRNA CTD PMID:27935865 NCBI chr17:10,300,865...10,373,006
Ensembl chr17:10,300,865...10,373,130 		JBrowse link
G MYH2 myosin heavy chain 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH2 mRNA CTD PMID:27935865 NCBI chr17:10,521,148...10,549,658
Ensembl chr17:10,521,148...10,549,700 		JBrowse link
G MYH4 myosin heavy chain 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH4 mRNA CTD PMID:27935865 NCBI chr17:10,443,263...10,469,559
Ensembl chr17:10,443,290...10,469,559 		JBrowse link
G MYL1 myosin light chain 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYL1 mRNA CTD PMID:27935865 NCBI chr 2:210,290,150...210,315,174
Ensembl chr 2:210,290,150...210,315,174 		JBrowse link
G MYL11 myosin light chain 11 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of MYLPF mRNA CTD PMID:27935865 NCBI chr16:30,370,934...30,377,991
Ensembl chr16:30,370,934...30,377,991 		JBrowse link
G MYL9 myosin light chain 9 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYL9 mRNA CTD PMID:27935865 NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447 		JBrowse link
G MYLK myosin light chain kinase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYLK mRNA CTD PMID:27935865 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332 		JBrowse link
G MYO18B myosin XVIIIB multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYO18B mRNA CTD PMID:27935865 NCBI chr22:25,742,188...26,063,847
Ensembl chr22:25,742,144...26,031,045 		JBrowse link
G MYO1C myosin IC increases expression EXP Pioglitazone results in increased expression of MYO1C mRNA CTD PMID:32589349 NCBI chr17:1,464,186...1,492,686
Ensembl chr17:1,464,186...1,492,686 		JBrowse link
G MYOM1 myomesin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOM1 mRNA CTD PMID:27935865 NCBI chr18:3,066,807...3,247,376
Ensembl chr18:3,066,807...3,219,968 		JBrowse link
G MYOM2 myomesin 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOM2 mRNA CTD PMID:27935865 NCBI chr 8:2,045,046...2,145,456
Ensembl chr 8:2,045,046...2,165,552 		JBrowse link
G MYOM3 myomesin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOM3 mRNA CTD PMID:27935865 NCBI chr 1:24,056,041...24,112,135
Ensembl chr 1:24,056,035...24,112,135 		JBrowse link
G MYOT myotilin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOT mRNA CTD PMID:27935865 NCBI chr 5:137,867,860...137,887,851
Ensembl chr 5:137,867,858...137,887,851 		JBrowse link
G MYOZ1 myozenin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOZ1 mRNA CTD PMID:27935865 NCBI chr10:73,631,612...73,641,474
Ensembl chr10:73,631,612...73,641,474 		JBrowse link
G MYOZ3 myozenin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOZ3 mRNA CTD PMID:27935865 NCBI chr 5:150,660,869...150,679,368
Ensembl chr 5:150,660,882...150,679,368 		JBrowse link
G MYPN myopalladin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYPN mRNA CTD PMID:27935865 NCBI chr10:68,087,897...68,212,017
Ensembl chr10:68,087,897...68,212,017 		JBrowse link
G MZB1 marginal zone B and B1 cell specific protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MZB1 mRNA CTD PMID:27935865 NCBI chr 5:139,387,467...139,389,913
Ensembl chr 5:139,387,467...139,390,081 		JBrowse link
G NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NAALAD2 mRNA CTD PMID:27935865 NCBI chr11:90,131,699...90,192,894
Ensembl chr11:90,131,515...90,192,894 		JBrowse link
G NDRG1 N-myc downstream regulated 1 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of NDRG1 mRNA CTD PMID:20847119 NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022 		JBrowse link
G NEB nebulin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NEB mRNA CTD PMID:27935865 NCBI chr 2:151,485,339...151,734,476
Ensembl chr 2:151,485,336...151,734,487 		JBrowse link
G NEGR1 neuronal growth regulator 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NEGR1 mRNA CTD PMID:27935865 NCBI chr 1:71,395,943...72,282,539
Ensembl chr 1:71,395,943...72,282,539 		JBrowse link
G NEXN nexilin F-actin binding protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NEXN mRNA CTD PMID:27935865 NCBI chr 1:77,888,624...77,943,895
Ensembl chr 1:77,888,513...77,943,895 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP NFE2L2 protein promotes the reaction [Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 mRNA]]; NFE2L2 protein promotes the reaction [Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 protein]]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 mRNA]; Pioglitazone promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 mRNA] CTD PMID:30965670 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKBIB NFKB inhibitor beta multiple interactions EXP pioglitazone inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIB protein] CTD PMID:17055343 NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893 		JBrowse link
G NKAIN3 sodium/potassium transporting ATPase interacting 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NKAIN3 mRNA CTD PMID:27935865 NCBI chr 8:62,248,854...62,999,652
Ensembl chr 8:62,248,591...63,014,000 		JBrowse link
G NKX3-1 NK3 homeobox 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NKX3-1 mRNA CTD PMID:27935865 NCBI chr 8:23,678,693...23,682,938
Ensembl chr 8:23,678,697...23,682,938 		JBrowse link
G NMRK2 nicotinamide riboside kinase 2 decreases expression EXP Pioglitazone results in decreased expression of NMRK2 mRNA CTD PMID:30031879 NCBI chr19:3,933,069...3,942,416
Ensembl chr19:3,933,069...3,942,416 		JBrowse link
G NOS2 nitric oxide synthase 2 decreases expression
affects expression
multiple interactions		 ISO
EXP		 pioglitazone results in decreased expression of NOS2 mRNA
pioglitazone affects the expression of NOS2
Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NOS2 protein]; Pioglitazone inhibits the reaction [Endotoxins results in increased expression of NOS2 protein]
pioglitazone inhibits the reaction [Homocysteine results in increased methylation of NOS2 promoter]		 CTD PMID:15364003 PMID:15817521 PMID:17492134 PMID:21962020 PMID:30343038 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions ISO Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of NOS3 protein] CTD PMID:30343038 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NOX1 NADPH oxidase 1 affects activity ISO pioglitazone affects the activity of NOX1 protein CTD PMID:21962020 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359 		JBrowse link
G NOX4 NADPH oxidase 4 multiple interactions ISO pioglitazone inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA] CTD PMID:16979161 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G NPHS1 NPHS1 adhesion molecule, nephrin increases expression
multiple interactions		 EXP Pioglitazone results in increased expression of NPHS1 mRNA
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Pioglitazone results in increased expression of NPHS1 mRNA]; Pioglitazone promotes the reaction [PPARG protein binds to NPHS1 promoter]		 CTD PMID:16687628 NCBI chr19:35,825,372...35,852,504
Ensembl chr19:35,825,372...35,869,287 		JBrowse link
G NPPB natriuretic peptide B decreases expression EXP Pioglitazone results in decreased expression of NPPB mRNA CTD PMID:30031879 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945 		JBrowse link
G NPY neuropeptide Y multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of NPY mRNA CTD PMID:27935865 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NPY1R mRNA CTD PMID:27935865 NCBI chr 4:163,323,962...163,344,689
Ensembl chr 4:163,323,962...163,344,832 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP NFE2L2 protein promotes the reaction [Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 mRNA]]; NFE2L2 protein promotes the reaction [Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 protein]]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 mRNA]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 protein]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NQO1 mRNA] CTD PMID:30965670 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 increases expression EXP pioglitazone results in increased expression of NR1H2 mRNA CTD PMID:19201410 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions
increases expression
affects response to substance		 EXP
ISO		 22-hydroxycholesterol promotes the reaction [pioglitazone results in increased expression of NR1H3 mRNA]; NR1H3 protein affects the reaction [pioglitazone results in increased expression of PPARA mRNA]
NR1H3 protein affects the susceptibility to pioglitazone		 CTD PMID:15381068 PMID:19201410 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 affects localization EXP Pioglitazone affects the localization of NR1I2 protein CTD PMID:31233785 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 increases expression ISO pioglitazone results in increased expression of NR4A1 mRNA CTD PMID:17785466 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 increases expression ISO pioglitazone results in increased expression of NR4A3 mRNA CTD PMID:17785466 NCBI chr 9:99,821,885...99,866,891
Ensembl chr 9:99,821,855...99,866,891 		JBrowse link
G NRAP nebulin related anchoring protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NRAP mRNA CTD PMID:27935865 NCBI chr10:113,588,714...113,664,041
Ensembl chr10:113,588,714...113,664,070 		JBrowse link
G NSG2 neuronal vesicle trafficking associated 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NSG2 mRNA CTD PMID:27935865 NCBI chr 5:174,045,706...174,109,179
Ensembl chr 5:174,045,706...174,243,501 		JBrowse link
G NUCB2 nucleobindin 2 increases stability EXP pioglitazone results in increased stability of NUCB2 mRNA CTD PMID:20427483 NCBI chr11:17,276,739...17,349,980
Ensembl chr11:17,208,153...17,349,980 		JBrowse link
G OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OBSCN mRNA CTD PMID:27935865 NCBI chr 1:228,208,044...228,378,876
Ensembl chr 1:228,208,044...228,378,876 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase multiple interactions ISO Pioglitazone inhibits the reaction [LEPR protein affects the expression of OGG1 protein] CTD PMID:35472412 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G OLFML1 olfactomedin like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OLFML1 mRNA CTD PMID:27935865 NCBI chr11:7,485,506...7,511,377
Ensembl chr11:7,485,388...7,511,377 		JBrowse link
G OPCML opioid binding protein/cell adhesion molecule like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OPCML mRNA CTD PMID:27935865 NCBI chr11:132,414,981...133,532,501
Ensembl chr11:132,414,977...133,532,501 		JBrowse link
G OPTC opticin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OPTC mRNA CTD PMID:27935865 NCBI chr 1:203,494,153...203,508,949
Ensembl chr 1:203,494,153...203,508,949 		JBrowse link
G PAX1 paired box 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PAX1 mRNA CTD PMID:27935865 NCBI chr20:21,705,664...21,718,481
Ensembl chr20:21,705,659...21,718,481 		JBrowse link
G PCDH18 protocadherin 18 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PCDH18 mRNA CTD PMID:27935865 NCBI chr 4:137,518,918...137,532,494
Ensembl chr 4:137,518,918...137,532,494 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PCK1 mRNA CTD PMID:27935865 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PCLO piccolo presynaptic cytomatrix protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PCLO mRNA CTD PMID:27935865 NCBI chr 7:82,754,012...83,162,884
Ensembl chr 7:82,754,012...83,162,930 		JBrowse link
G PCOLCE2 procollagen C-endopeptidase enhancer 2 increases expression EXP Pioglitazone results in increased expression of PCOLCE2 mRNA CTD PMID:30031879 NCBI chr 3:142,817,874...142,889,083
Ensembl chr 3:142,815,922...142,889,206 		JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 multiple interactions
increases expression		 EXP
ISO		 pioglitazone promotes the reaction [PPARG protein results in increased expression of PCSK9 mRNA]
pioglitazone results in increased expression of PCSK9 protein
[pioglitazone co-treated with U 0126] results in increased secretion of PCSK9 protein
pioglitazone results in increased expression of PCSK9 mRNA; pioglitazone results in increased expression of PCSK9 protein		 CTD PMID:22593575 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,447...55,064,852 		JBrowse link
G PDE6C phosphodiesterase 6C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PDE6C mRNA CTD PMID:27935865 NCBI chr10:93,612,537...93,666,010
Ensembl chr10:93,612,537...93,666,010 		JBrowse link
G PDGFB platelet derived growth factor subunit B multiple interactions EXP [PDGFB protein binds to PDGFB protein] inhibits the reaction [pioglitazone results in decreased phosphorylation of MAPK1 protein]; [PDGFB protein binds to PDGFB protein] inhibits the reaction [pioglitazone results in decreased phosphorylation of MAPK3 protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased degradation of CDKN1B protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CCND1 protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CDKN1A protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of EIF4EBP1 protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6KB1 protein]; PRKAA1 protein affects the reaction [pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]] CTD PMID:26643070 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PDGFRA mRNA CTD PMID:27935865 NCBI chr 4:54,229,293...54,298,245
Ensembl chr 4:54,229,280...54,298,245 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 increases expression EXP Pioglitazone results in increased expression of PDK4 mRNA CTD PMID:30031879 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516 		JBrowse link
G PEG10 paternally expressed 10 increases expression EXP Pioglitazone results in increased expression of PEG10 mRNA CTD PMID:30031879 NCBI chr 7:94,656,325...94,669,695
Ensembl chr 7:94,656,325...94,669,695 		JBrowse link
G PERM1 PPARGC1 and ESRR induced regulator, muscle 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PERM1 mRNA CTD PMID:27935865 NCBI chr 1:975,198...982,093
Ensembl chr 1:975,198...982,117 		JBrowse link
G PGAM2 phosphoglycerate mutase 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PGAM2 mRNA CTD PMID:27935865 NCBI chr 7:44,062,727...44,065,567
Ensembl chr 7:44,062,727...44,065,567 		JBrowse link
G PGM5 phosphoglucomutase 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PGM5 mRNA CTD PMID:27935865 NCBI chr 9:68,356,611...68,531,061
Ensembl chr 9:68,328,308...68,531,061 		JBrowse link
G PHACTR1 phosphatase and actin regulator 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PHACTR1 mRNA CTD PMID:27935865 NCBI chr 6:12,716,767...13,287,837
Ensembl chr 6:12,716,312...13,290,446 		JBrowse link
G PHETA2 PH domain containing endocytic trafficking adaptor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PHETA2 mRNA CTD PMID:27935865 NCBI chr22:42,074,248...42,079,438
Ensembl chr22:42,074,248...42,079,438 		JBrowse link
G PHEX phosphate regulating endopeptidase X-linked multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PHEX mRNA CTD PMID:27935865 NCBI chr  X:22,032,325...22,251,310
Ensembl chr  X:22,032,325...22,494,713 		JBrowse link
G PHGR1 proline, histidine and glycine rich 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of PHGR1 mRNA CTD PMID:27935865 NCBI chr15:40,351,033...40,356,434
Ensembl chr15:40,351,033...40,356,434 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 increases expression EXP Pioglitazone results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 2:229,023,973...229,271,287
Ensembl chr 2:228,850,526...229,271,287 		JBrowse link
G PIEZO2 piezo type mechanosensitive ion channel component 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PIEZO2 mRNA CTD PMID:27935865 NCBI chr18:10,670,247...11,149,569
Ensembl chr18:10,666,483...11,149,569 		JBrowse link
G PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 multiple interactions EXP [Metformin co-treated with Pioglitazone] results in decreased expression of PIK3C3 mRNA CTD PMID:32589349 NCBI chr18:41,955,234...42,087,830
Ensembl chr18:41,955,234...42,087,830 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha multiple interactions
decreases expression		 EXP [Metformin co-treated with Pioglitazone] results in decreased expression of PIK3CA mRNA
Pioglitazone results in decreased expression of PIK3CA mRNA		 CTD PMID:32589349 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta multiple interactions EXP [Metformin co-treated with Pioglitazone] results in decreased expression of PIK3CB mRNA CTD PMID:32589349 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma multiple interactions EXP [Metformin co-treated with Pioglitazone] results in decreased expression of PIK3CG mRNA CTD PMID:32589349 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G PKNOX2 PBX/knotted 1 homeobox 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PKNOX2 mRNA CTD PMID:27935865 NCBI chr11:125,164,751...125,433,389
Ensembl chr11:125,164,687...125,433,389 		JBrowse link
G PLAAT1 phospholipase A and acyltransferase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of PLAAT1 mRNA CTD PMID:27935865 NCBI chr 3:193,240,606...193,281,426
Ensembl chr 3:193,241,128...193,277,738 		JBrowse link
G PLD1 phospholipase D1 multiple interactions
decreases expression		 EXP [Metformin co-treated with Pioglitazone] results in decreased expression of PLD1 mRNA
Pioglitazone results in decreased expression of PLD1 mRNA		 CTD PMID:32589349 NCBI chr 3:171,600,404...171,810,483
Ensembl chr 3:171,600,404...171,810,950 		JBrowse link
G PLEK pleckstrin decreases expression EXP Pioglitazone results in decreased expression of PLEK mRNA CTD PMID:30031879 NCBI chr 2:68,365,282...68,397,453
Ensembl chr 2:68,365,282...68,397,453 		JBrowse link
G PLIN1 perilipin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of PLIN1 mRNA; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA] CTD PMID:27935865 PMID:32473317 NCBI chr15:89,664,367...89,679,367
Ensembl chr15:89,664,367...89,679,427 		JBrowse link
G PLIN2 perilipin 2 increases expression EXP Pioglitazone results in increased expression of PLIN2 mRNA CTD PMID:15381068 PMID:30031879 NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290 		JBrowse link
G PLIN4 perilipin 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PLIN4 mRNA CTD PMID:27935865 NCBI chr19:4,502,192...4,518,486
Ensembl chr19:4,502,192...4,518,486 		JBrowse link
G PLN phospholamban multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PLN mRNA CTD PMID:27935865 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716 		JBrowse link
G PNMA8B PNMA family member 8B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of PNMA8B mRNA CTD PMID:27935865 NCBI chr19:46,491,191...46,495,867
Ensembl chr19:46,486,906...46,495,879 		JBrowse link
G POR cytochrome p450 oxidoreductase increases expression ISO pioglitazone results in increased expression of POR mRNA CTD PMID:16597547 NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions
increases activity
affects binding
increases expression
affects response to substance		 ISO
EXP		 pioglitazone binds to and results in increased activity of PPARA protein
pioglitazone results in increased activity of PPARA protein
pioglitazone binds to PPARA protein
pioglitazone results in increased expression of PPARA mRNA
PPARA protein affects the susceptibility to pioglitazone
pioglitazone results in increased expression of PPARA mRNA; pioglitazone results in increased expression of PPARA protein
NR1H3 protein affects the reaction [pioglitazone results in increased expression of PPARA mRNA]; pioglitazone results in increased activity of [PPARA protein binds to RXRA protein]		 CTD PMID:11172467 PMID:11779144 PMID:15273253 PMID:16751799 PMID:19201410 More... NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta affects binding
increases expression
increases activity
multiple interactions		 EXP
ISO		 pioglitazone binds to PPARB protein; pioglitazone binds to PPARD protein
pioglitazone results in increased expression of PPARD mRNA
pioglitazone results in increased activity of PPARD protein
pioglitazone results in increased activity of [PPARD protein binds to RXRA protein]		 CTD PMID:11779144 PMID:19201410 PMID:23150725 PMID:23843199 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions
affects expression
increases activity
affects binding
increases expression
affects response to substance		 EXP
ISO		 [Dexamethasone co-treated with INS protein co-treated with Pioglitazone] results in increased expression of PPARG protein; Ethanol inhibits the reaction [Pioglitazone results in increased activity of PPARG protein]; GW 1929 inhibits the reaction [Pioglitazone results in increased expression of PPARG protein]; luzindole inhibits the reaction [Pioglitazone results in increased expression of PPARG protein]; Melatonin promotes the reaction [Pioglitazone results in increased expression of PPARG protein]; Pioglitazone binds to and results in increased activity of PPARG protein; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of PPARG protein]; Pioglitazone inhibits the reaction [GW 1929 binds to PPARG protein]; Pioglitazone promotes the reaction [Melatonin results in increased expression of PPARG protein]; Pioglitazone promotes the reaction [PPARG protein binds to NPHS1 promoter]; Pioglitazone promotes the reaction [PPARG protein results in increased expression of PCSK9 mRNA]; Pioglitazone results in increased activity of [PPARG protein alternative form binds to RXRA protein]; PPARG protein affects the reaction [Pioglitazone results in increased expression of CD36 protein]; PPARG protein promotes the reaction [Pioglitazone results in increased activity of DIO2 protein]; Ro 41-5253 inhibits the reaction [Pioglitazone results in increased activity of PPARG protein]
pioglitazone affects the expression of PPARG mRNA; pioglitazone affects the expression of PPARG protein
Pioglitazone binds to PPARG protein
pioglitazone results in increased expression of PPARG mRNA
Pioglitazone results in increased expression of PPARG mRNA; Pioglitazone results in increased expression of PPARG mRNA alternative form; Pioglitazone results in increased expression of PPARG protein
pioglitazone results in increased activity of PPARG protein
PPARG protein affects the susceptibility to pioglitazone
2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone affects the expression of PPARG mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone affects the expression of PPARG protein]; [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in decreased expression of PPARG mRNA]; [Pioglitazone binds to and results in increased activity of PPARG protein] promotes the reaction [Dietary Fats results in increased abundance of Diglycerides]; [Pioglitazone binds to and results in increased activity of PPARG protein] promotes the reaction [Dietary Fats results in increased abundance of Phospholipids]; [Pioglitazone binds to and results in increased activity of PPARG protein] promotes the reaction [Dietary Fats results in increased abundance of Triglycerides]; [Pioglitazone results in increased activity of PPARG protein] which results in decreased abundance of Triglycerides; [Pioglitazone results in increased activity of PPARG protein] which results in increased abundance of Diglycerides; Pioglitazone affects the reaction [Puromycin Aminonucleoside results in increased expression of PPARG protein]; Pioglitazone binds to and results in increased activity of PPARG protein; Pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Cisplatin results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Fructose results in decreased activity of PPARG protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; T 0070907 inhibits the reaction [Pioglitazone affects the expression of PPARG mRNA]; T 0070907 inhibits the reaction [Pioglitazone affects the expression of PPARG protein]
pioglitazone affects the expression of PPARG; pioglitazone affects the expression of PPARG mRNA
[ANGPT2 protein binds to and results in increased activity of AGTR2 protein] promotes the reaction [pioglitazone binds to and results in increased activity of PPARG protein]; [Dexamethasone co-treated with INS protein co-treated with pioglitazone] results in increased expression of PPARG protein; [pioglitazone binds to and results in increased activity of PPARG protein] which results in increased expression of RETSAT mRNA; [pioglitazone co-treated with alitretinoin] inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; pioglitazone binds to and results in increased activity of PPARG protein; pioglitazone inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; pioglitazone promotes the reaction [PPARG protein binds to SCNN1G intron]; pioglitazone promotes the reaction [Toluene 2,4-Diisocyanate results in increased localization of PPARG protein]; pioglitazone results in increased activity of and results in decreased expression of PPARG protein; PPARG protein affects the reaction [pioglitazone results in increased expression of ADIPOQ mRNA]		 CTD PMID:9836514 PMID:11172467 PMID:11779144 PMID:11991651 PMID:12055599 More... NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha decreases expression
multiple interactions		 ISO
EXP		 pioglitazone results in decreased expression of PPARGC1A mRNA
Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of PPARGC1A protein]		 CTD PMID:22456468 PMID:27366949 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PPBP pro-platelet basic protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of PPBP mRNA CTD PMID:27935865 NCBI chr 4:73,986,439...73,988,190
Ensembl chr 4:73,986,439...73,988,190 		JBrowse link
G PPP1R3A protein phosphatase 1 regulatory subunit 3A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PPP1R3A mRNA CTD PMID:27935865 NCBI chr 7:113,876,777...113,919,009
Ensembl chr 7:113,876,777...114,075,920 		JBrowse link
G PPP1R3C protein phosphatase 1 regulatory subunit 3C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PPP1R3C mRNA CTD PMID:27935865 NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha increases expression EXP Pioglitazone results in increased expression of PPP2CA mRNA CTD PMID:32589349 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073 		JBrowse link
G PPP2R2B protein phosphatase 2 regulatory subunit Bbeta increases expression EXP Pioglitazone results in increased expression of PPP2R2B mRNA CTD PMID:32589349 NCBI chr 5:146,580,742...147,081,520
Ensembl chr 5:146,580,742...147,084,784 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions EXP PRKAA1 protein affects the reaction [pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]]; PRKAA1 protein affects the reaction [pioglitazone results in increased expression of CDKN1B protein]; PRKAA1 protein affects the reaction [pioglitazone results in increased phosphorylation of RPTOR protein] CTD PMID:26643070 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKCA protein kinase C alpha decreases expression
multiple interactions		 EXP Pioglitazone results in decreased expression of PRKCA mRNA
[Metformin co-treated with Pioglitazone] results in decreased expression of PRKCA mRNA		 CTD PMID:32589349 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743 		JBrowse link
G PRKCG protein kinase C gamma increases expression EXP Pioglitazone results in increased expression of PRKCG mRNA CTD PMID:32589349 NCBI chr19:53,881,094...53,907,652
Ensembl chr19:53,879,190...53,907,652 		JBrowse link
G PRKCQ protein kinase C theta multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PRKCQ mRNA CTD PMID:27935865 NCBI chr10:6,394,097...6,580,646
Ensembl chr10:6,427,143...6,580,301 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PRKG1 mRNA CTD PMID:27935865 NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423 		JBrowse link
G PRNP prion protein (Kanno blood group) multiple interactions
increases expression		 EXP GW 1929 inhibits the reaction [Pioglitazone results in increased expression of PRNP protein]; luzindole inhibits the reaction [Pioglitazone results in increased expression of PRNP protein]; Melatonin promotes the reaction [Pioglitazone results in increased expression of PRNP protein]; Pioglitazone promotes the reaction [Melatonin results in increased expression of PRNP protein]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]]]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in decreased expression of RGN protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in increased expression of CDKN1A protein]]] CTD PMID:29734669 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590 		JBrowse link
G PROK2 prokineticin 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of PROK2 mRNA CTD PMID:27935865 NCBI chr 3:71,771,655...71,785,148
Ensembl chr 3:71,771,655...71,785,206 		JBrowse link
G PRR32 proline rich 32 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PRR32 mRNA CTD PMID:27935865 NCBI chr  X:126,819,729...126,821,786
Ensembl chr  X:126,819,729...126,821,786 		JBrowse link
G PRR33 proline rich 33 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PRR33 mRNA CTD PMID:27935865 NCBI chr11:1,887,987...1,917,708
Ensembl chr11:1,888,078...1,891,895 		JBrowse link
G PRSS2 serine protease 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of PRSS2 mRNA CTD PMID:27935865 NCBI chr 7:142,770,970...142,774,560
Ensembl chr 7:142,760,398...142,774,564 		JBrowse link
G PRXL2B peroxiredoxin like 2B decreases expression EXP Pioglitazone results in decreased expression of PRXL2B mRNA CTD PMID:30031879 NCBI chr 1:2,586,523...2,591,468
Ensembl chr 1:2,586,491...2,591,469 		JBrowse link
G PSORS1C2 psoriasis susceptibility 1 candidate 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of PSORS1C2 mRNA CTD PMID:27935865 NCBI chr 6:31,137,534...31,139,066
Ensembl chr 6:31,137,534...31,139,066 		JBrowse link
G PTEN phosphatase and tensin homolog increases expression EXP Pioglitazone results in increased expression of PTEN mRNA CTD PMID:32589349 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGFR prostaglandin F receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PTGFR mRNA CTD PMID:27935865 NCBI chr 1:78,490,974...78,540,701
Ensembl chr 1:78,303,884...78,540,701 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
decreases expression		 ISO
EXP		 [Atorvastatin co-treated with Pioglitazone] results in increased expression of PTGS2 protein
Pioglitazone results in increased expression of PTGS2 mRNA
pioglitazone results in decreased expression of PTGS2 protein
pioglitazone results in decreased expression of PTGS2 mRNA		 CTD PMID:15817521 PMID:16386242 PMID:16908763 PMID:32816093 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PVALB parvalbumin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PVALB mRNA CTD PMID:27935865 NCBI chr22:36,800,703...36,819,499
Ensembl chr22:36,800,684...36,819,479 		JBrowse link
G PXMP2 peroxisomal membrane protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PXMP2 mRNA CTD PMID:27935865 NCBI chr12:132,687,587...132,704,985
Ensembl chr12:132,687,587...132,704,985 		JBrowse link
G PYGM glycogen phosphorylase, muscle associated multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PYGM mRNA CTD PMID:27935865 NCBI chr11:64,746,389...64,760,715
Ensembl chr11:64,746,389...64,759,974 		JBrowse link
G RALYL RALY RNA binding protein like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RALYL mRNA CTD PMID:27935865 NCBI chr 8:84,182,787...84,921,844
Ensembl chr 8:84,182,787...84,921,844 		JBrowse link
G RANBP2 RAN binding protein 2 multiple interactions EXP pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of RANBP2 mRNA] CTD PMID:20847119 NCBI chr 2:108,719,482...109,842,301
Ensembl chr 2:108,719,482...108,785,810 		JBrowse link
G RASD2 RASD family member 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RASD2 mRNA CTD PMID:27935865 NCBI chr22:35,532,806...35,553,999
Ensembl chr22:35,540,831...35,553,999 		JBrowse link
G RASL12 RAS like family 12 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RASL12 mRNA CTD PMID:27935865 NCBI chr15:65,045,580...65,076,667
Ensembl chr15:65,053,337...65,076,690 		JBrowse link
G RB1 RB transcriptional corepressor 1 multiple interactions EXP pioglitazone results in decreased phosphorylation of and results in decreased expression of RB1 protein CTD PMID:15729575 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G RCAN2 regulator of calcineurin 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RCAN2 mRNA CTD PMID:27935865 NCBI chr 6:46,220,736...46,491,970
Ensembl chr 6:46,220,736...46,491,972 		JBrowse link
G RDH10 retinol dehydrogenase 10 increases expression EXP Pioglitazone results in increased expression of RDH10 mRNA CTD PMID:30031879 NCBI chr 8:73,294,602...73,325,281
Ensembl chr 8:73,294,602...73,325,281 		JBrowse link
G REEP3 receptor accessory protein 3 multiple interactions EXP pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of REEP3 mRNA] CTD PMID:20847119 NCBI chr10:63,521,401...63,625,128
Ensembl chr10:63,521,401...63,625,128 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
affects expression		 ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased localization of RELA protein]
pioglitazone affects the expression of RELA mRNA; pioglitazone affects the expression of RELA protein
2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone affects the expression of RELA mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone affects the expression of RELA protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]; Pioglitazone inhibits the reaction [Aldosterone results in increased activity of RELA protein]; Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of RELA protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]; T 0070907 inhibits the reaction [Pioglitazone affects the expression of RELA mRNA]; T 0070907 inhibits the reaction [Pioglitazone affects the expression of RELA protein]		 CTD PMID:17015710 PMID:18660453 PMID:28744220 PMID:36988379 PMID:37044004 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RETN resistin multiple interactions
increases secretion
increases expression		 ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of RETN mRNA; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased expression of RETN mRNA]; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased secretion of RETN protein]
Pioglitazone results in increased secretion of RETN protein
Pioglitazone results in increased expression of RETN mRNA		 CTD PMID:27918843 PMID:27935865 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455 		JBrowse link
G RETSAT retinol saturase multiple interactions
increases expression		 ISO [pioglitazone binds to and results in increased activity of PPARG protein] which results in increased expression of RETSAT mRNA
pioglitazone results in increased expression of RETSAT mRNA; pioglitazone results in increased expression of RETSAT protein		 CTD PMID:19139408 NCBI chr 2:85,341,955...85,354,528
Ensembl chr 2:85,341,955...85,354,531 		JBrowse link
G RGCC regulator of cell cycle decreases expression EXP Pioglitazone results in decreased expression of RGCC mRNA CTD PMID:30031879 NCBI chr13:41,457,550...41,470,871
Ensembl chr13:41,457,550...41,470,871 		JBrowse link
G RGN regucalcin multiple interactions EXP Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]]; Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]; Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in decreased expression of RGN protein]]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in decreased expression of RGN protein]]] CTD PMID:29734669 NCBI chr  X:47,078,443...47,093,313
Ensembl chr  X:47,078,355...47,093,314 		JBrowse link
G RGS1 regulator of G protein signaling 1 decreases expression EXP Pioglitazone results in decreased expression of RGS1 mRNA CTD PMID:30031879 NCBI chr 1:192,575,773...192,580,024
Ensembl chr 1:192,575,763...192,580,024 		JBrowse link
G RGS13 regulator of G protein signaling 13 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RGS13 mRNA CTD PMID:27935865 NCBI chr 1:192,636,147...192,660,311
Ensembl chr 1:192,636,138...192,660,311 		JBrowse link
G RGS5 regulator of G protein signaling 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RGS5 mRNA CTD PMID:27935865 NCBI chr 1:163,142,299...163,321,735
Ensembl chr 1:163,111,121...163,321,791 		JBrowse link
G RGS7BP regulator of G protein signaling 7 binding protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RGS7BP mRNA CTD PMID:27935865 NCBI chr 5:64,506,015...64,612,319
Ensembl chr 5:64,506,015...64,612,319 		JBrowse link
G RHEB Ras homolog, mTORC1 binding increases expression EXP Pioglitazone results in increased expression of RHEB mRNA CTD PMID:32589349 NCBI chr 7:151,466,012...151,519,895
Ensembl chr 7:151,466,012...151,520,120 		JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 multiple interactions EXP [Metformin co-treated with Pioglitazone] results in decreased expression of RICTOR mRNA; Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of RICTOR mRNA] CTD PMID:20847119 PMID:32589349 NCBI chr 5:38,937,920...39,074,399
Ensembl chr 5:38,937,920...39,074,402 		JBrowse link
G RIOX1 ribosomal oxygenase 1 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of RIOX1 mRNA CTD PMID:20847119 NCBI chr14:73,490,933...73,493,394
Ensembl chr14:73,490,933...73,493,394 		JBrowse link
G RNASE6 ribonuclease A family member k6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RNASE6 mRNA CTD PMID:27935865 NCBI chr14:20,781,070...20,782,467
Ensembl chr14:20,781,268...20,782,467 		JBrowse link
G RNU1-3 RNA, U1 small nuclear 3 decreases expression EXP Pioglitazone results in decreased expression of RNU1-3 mRNA CTD PMID:30031879 NCBI chr 1:16,666,785...16,666,948
Ensembl chr 1:16,666,785...16,666,948 		JBrowse link
G RNVU1-18 RNA, variant U1 small nuclear 18 decreases expression EXP Pioglitazone results in decreased expression of RNVU1-18 mRNA CTD PMID:30031879 NCBI chr 1:143,729,407...143,729,570
Ensembl chr 1:143,729,407...143,729,570 		JBrowse link
G RNVU1-7 RNA, variant U1 small nuclear 7 decreases expression EXP Pioglitazone results in decreased expression of RNVU1-7 mRNA CTD PMID:30031879 NCBI chr 1:148,038,753...148,038,916
Ensembl chr 1:148,038,753...148,038,916 		JBrowse link
G ROBO3 roundabout guidance receptor 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of ROBO3 mRNA CTD PMID:27935865 NCBI chr11:124,865,432...124,881,471
Ensembl chr11:124,865,432...124,881,471 		JBrowse link
G RORC RAR related orphan receptor C increases expression ISO pioglitazone results in increased expression of RORC mRNA CTD PMID:9543393 NCBI chr 1:151,806,071...151,831,802
Ensembl chr 1:151,806,071...151,831,845 		JBrowse link
G RPL3L ribosomal protein L3 like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RPL3L mRNA CTD PMID:27935865 NCBI chr16:1,943,974...1,954,689
Ensembl chr16:1,943,974...1,957,606 		JBrowse link
G RPS6 ribosomal protein S6 decreases phosphorylation
decreases expression
multiple interactions		 EXP pioglitazone results in decreased phosphorylation of RPS6 protein
Pioglitazone results in decreased expression of RPS6 mRNA
pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]; PRKAA1 protein affects the reaction [pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]]		 CTD PMID:26643070 PMID:32589349 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236 		JBrowse link
G RPS6KA1 ribosomal protein S6 kinase A1 increases expression EXP Pioglitazone results in increased expression of RPS6KA1 mRNA CTD PMID:32589349 NCBI chr 1:26,529,761...26,575,025
Ensembl chr 1:26,529,761...26,575,030 		JBrowse link
G RPS6KA2 ribosomal protein S6 kinase A2 multiple interactions
increases expression		 EXP [Metformin co-treated with Pioglitazone] results in increased expression of RPS6KA2 mRNA
Pioglitazone results in increased expression of RPS6KA2 mRNA		 CTD PMID:32589349 NCBI chr 6:166,409,364...166,862,773
Ensembl chr 6:166,409,364...166,906,451 		JBrowse link
G RPS6KA5 ribosomal protein S6 kinase A5 multiple interactions EXP [Metformin co-treated with Pioglitazone] results in decreased expression of RPS6KA5 mRNA CTD PMID:32589349 NCBI chr14:90,847,861...91,060,641
Ensembl chr14:90,847,861...91,060,641 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 multiple interactions
decreases phosphorylation		 EXP pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6KB1 protein]
pioglitazone results in decreased phosphorylation of RPS6KB1 protein		 CTD PMID:26643070 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G RPTOR regulatory associated protein of MTOR complex 1 increases phosphorylation
multiple interactions		 EXP pioglitazone results in increased phosphorylation of RPTOR protein
PRKAA1 protein affects the reaction [pioglitazone results in increased phosphorylation of RPTOR protein]		 CTD PMID:26643070 NCBI chr17:80,544,838...80,966,368
Ensembl chr17:80,544,819...80,966,371 		JBrowse link
G RPUSD2 RNA pseudouridine synthase domain containing 2 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of RPUSD2 mRNA CTD PMID:20847119 NCBI chr15:40,569,299...40,574,949
Ensembl chr15:40,569,299...40,574,949 		JBrowse link
G RSPO1 R-spondin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RSPO1 mRNA CTD PMID:27935865 NCBI chr 1:37,611,350...37,634,892
Ensembl chr 1:37,611,350...37,634,892 		JBrowse link
G RTL3 retrotransposon Gag like 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RTL3 mRNA CTD PMID:27935865 NCBI chr  X:78,656,068...78,659,328
Ensembl chr  X:78,656,068...78,659,328 		JBrowse link
G RTN2 reticulon 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RTN2 mRNA CTD PMID:27935865 NCBI chr19:45,485,294...45,497,047
Ensembl chr19:45,485,294...45,497,055 		JBrowse link
G RUNX1T1 RUNX1 partner transcriptional co-repressor 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RUNX1T1 mRNA CTD PMID:27935865 NCBI chr 8:91,954,967...92,103,385
Ensembl chr 8:91,954,972...92,103,385 		JBrowse link
G RXRA retinoid X receptor alpha multiple interactions EXP pioglitazone results in increased activity of [PPARA protein binds to RXRA protein]; pioglitazone results in increased activity of [PPARD protein binds to RXRA protein]; pioglitazone results in increased activity of [PPARG protein alternative form binds to RXRA protein] CTD PMID:11779144 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585 		JBrowse link
G RYR1 ryanodine receptor 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RYR1 mRNA CTD PMID:27935865 NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273 		JBrowse link
G S100A8 S100 calcium binding protein A8 multiple interactions
decreases expression
increases expression		 ISO
EXP		 [pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of S100A8 mRNA
Pioglitazone results in decreased expression of S100A8 mRNA
pioglitazone results in increased expression of S100A8 mRNA		 CTD PMID:28138970 PMID:28263783 PMID:30031879 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073 		JBrowse link
G S100A9 S100 calcium binding protein A9 multiple interactions
increases expression		 ISO
EXP		 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of S100A9 mRNA; [pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of S100A9 mRNA
pioglitazone results in increased expression of S100A9 mRNA		 CTD PMID:27935865 PMID:28138970 PMID:28263783 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023 		JBrowse link
G SAA3P serum amyloid A3, pseudogene multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SAA3 mRNA CTD PMID:27935865 NCBI chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132 		JBrowse link
G SBK2 SH3 domain binding kinase family member 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SBK2 mRNA CTD PMID:27935865 NCBI chr19:55,528,611...55,537,133
Ensembl chr19:55,528,611...55,537,133 		JBrowse link
G SBK3 SH3 domain binding kinase family member 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SBK3 mRNA CTD PMID:27935865 NCBI chr19:55,540,656...55,545,543
Ensembl chr19:55,540,656...55,545,543 		JBrowse link
G SBSPON somatomedin B and thrombospondin type 1 domain containing multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SBSPON mRNA CTD PMID:27935865 NCBI chr 8:73,064,543...73,093,172
Ensembl chr 8:73,064,543...73,124,088 		JBrowse link
G SCARB1 scavenger receptor class B member 1 decreases expression ISO pioglitazone results in decreased expression of SCARB1 mRNA CTD PMID:20503262 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668 		JBrowse link
G SCD stearoyl-CoA desaturase multiple interactions EXP Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA] CTD PMID:32613381 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826 		JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCGB3A2 mRNA CTD PMID:27935865 NCBI chr 5:147,878,711...147,882,191
Ensembl chr 5:147,870,682...147,882,191 		JBrowse link
G SCN2A sodium voltage-gated channel alpha subunit 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN2A mRNA CTD PMID:27935865 NCBI chr 2:165,239,414...165,392,304
Ensembl chr 2:165,194,993...165,392,310 		JBrowse link
G SCN4A sodium voltage-gated channel alpha subunit 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN4A mRNA CTD PMID:27935865 NCBI chr17:63,938,554...63,972,918
Ensembl chr17:63,938,554...63,972,918 		JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN4B mRNA CTD PMID:27935865 NCBI chr11:118,133,377...118,152,823
Ensembl chr11:118,133,377...118,152,888 		JBrowse link
G SCN7A sodium voltage-gated channel alpha subunit 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN7A mRNA CTD PMID:27935865 NCBI chr 2:166,403,573...166,494,249
Ensembl chr 2:166,403,573...166,611,482 		JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma multiple interactions
increases expression		 ISO pioglitazone promotes the reaction [PPARG protein binds to SCNN1G intron]
pioglitazone results in increased expression of SCNN1G mRNA		 CTD PMID:16007095 NCBI chr16:23,182,745...23,216,883
Ensembl chr16:23,182,745...23,216,883 		JBrowse link
G SCUBE1 signal peptide, CUB domain and EGF like domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCUBE1 mRNA CTD PMID:27935865 NCBI chr22:43,197,280...43,343,372
Ensembl chr22:43,197,280...43,343,372 		JBrowse link
G SEC31B SEC31 homolog B, COPII coat complex component multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SEC31B mRNA CTD PMID:27935865 NCBI chr10:100,486,647...100,519,861
Ensembl chr10:100,486,646...100,519,864 		JBrowse link
G SELE selectin E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SELE mRNA CTD PMID:27935865 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G SELP selectin P multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SELP mRNA CTD PMID:27935865 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193 		JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions
increases expression		 ISO
EXP		 pioglitazone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SERPINE1 mRNA]
pioglitazone results in increased expression of SERPINE1 mRNA		 CTD PMID:16598202 PMID:21757225 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SFRP2 secreted frizzled related protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SFRP2 mRNA CTD PMID:27935865 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083 		JBrowse link
G SFRP4 secreted frizzled related protein 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SFRP4 mRNA CTD PMID:27935865 NCBI chr 7:37,905,932...37,916,817
Ensembl chr 7:37,905,932...38,025,695 		JBrowse link
G SFTPA1 surfactant protein A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SFTPA1 mRNA CTD PMID:27935865 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455 		JBrowse link
G SGCA sarcoglycan alpha multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SGCA mRNA CTD PMID:27935865 NCBI chr17:50,166,005...50,175,928
Ensembl chr17:50,164,214...50,175,928 		JBrowse link
G SGCE sarcoglycan epsilon multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SGCE mRNA CTD PMID:27935865 NCBI chr 7:94,584,980...94,656,133
Ensembl chr 7:94,524,204...94,656,572 		JBrowse link
G SGCG sarcoglycan gamma multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SGCG mRNA CTD PMID:27935865 NCBI chr13:23,160,508...23,325,162
Ensembl chr13:23,180,979...23,325,162 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 decreases expression EXP Pioglitazone results in decreased expression of SGK1 mRNA CTD PMID:32589349 NCBI chr 6:134,169,256...134,318,112
Ensembl chr 6:134,169,248...134,318,112 		JBrowse link
G SH2D5 SH2 domain containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SH2D5 mRNA CTD PMID:27935865 NCBI chr 1:20,719,731...20,732,703
Ensembl chr 1:20,719,731...20,732,837 		JBrowse link
G SH2D7 SH2 domain containing 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SH2D7 mRNA CTD PMID:27935865 NCBI chr15:78,090,122...78,104,362
Ensembl chr15:78,077,808...78,104,370 		JBrowse link
G SHE Src homology 2 domain containing E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SHE mRNA CTD PMID:27935865 NCBI chr 1:154,469,637...154,502,412
Ensembl chr 1:154,469,772...154,502,412 		JBrowse link
G SLC17A8 solute carrier family 17 member 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC17A8 mRNA CTD PMID:27935865 NCBI chr12:100,357,074...100,422,055
Ensembl chr12:100,357,074...100,422,055 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP pioglitazone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638 		JBrowse link
G SLC25A24 solute carrier family 25 member 24 decreases expression EXP Pioglitazone results in decreased expression of SLC25A24 mRNA CTD PMID:30031879 NCBI chr 1:108,134,043...108,200,343
Ensembl chr 1:108,134,043...108,200,849 		JBrowse link
G SLC25A34 solute carrier family 25 member 34 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC25A34 mRNA CTD PMID:27935865 NCBI chr 1:15,736,258...15,741,392
Ensembl chr 1:15,736,258...15,741,392 		JBrowse link
G SLC25A53 solute carrier family 25 member 53 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC25A53 mRNA CTD PMID:27935865 NCBI chr  X:104,099,214...104,157,009
Ensembl chr  X:104,099,214...104,157,009 		JBrowse link
G SLC26A7 solute carrier family 26 member 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC26A7 mRNA CTD PMID:27935865 NCBI chr 8:91,209,496...91,398,155
Ensembl chr 8:91,209,494...91,398,155 		JBrowse link
G SLC27A1 solute carrier family 27 member 1 increases expression ISO pioglitazone results in increased expression of SLC27A1 mRNA CTD PMID:20723549 NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168 		JBrowse link
G SLC2A14 solute carrier family 2 member 14 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of SLC2A14 mRNA CTD PMID:20847119 NCBI chr12:7,812,514...7,891,196
Ensembl chr12:7,812,512...7,891,148 		JBrowse link
G SLC2A3 solute carrier family 2 member 3 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of SLC2A3 mRNA CTD PMID:20847119 NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...8,019,007 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 multiple interactions ISO pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA] CTD PMID:27350165 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G SLC2A5 solute carrier family 2 member 5 multiple interactions
decreases expression		 ISO
EXP		 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC2A5 mRNA
Pioglitazone results in decreased expression of SLC2A5 mRNA		 CTD PMID:27935865 PMID:30031879 NCBI chr 1:9,035,106...9,094,195
Ensembl chr 1:9,035,106...9,088,478 		JBrowse link
G SLC2A6 solute carrier family 2 member 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SLC2A6 mRNA CTD PMID:27935865 NCBI chr 9:133,471,094...133,479,099
Ensembl chr 9:133,471,094...133,479,127 		JBrowse link
G SLC38A5 solute carrier family 38 member 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC38A5 mRNA CTD PMID:27935865 NCBI chr  X:48,458,544...48,470,260
Ensembl chr  X:48,458,537...48,470,260 		JBrowse link
G SLC4A5 solute carrier family 4 member 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC4A5 mRNA CTD PMID:27935865 NCBI chr 2:74,216,242...74,343,416
Ensembl chr 2:74,216,242...74,343,416 		JBrowse link
G SLC5A7 solute carrier family 5 member 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC5A7 mRNA CTD PMID:27935865 NCBI chr 2:107,986,524...108,013,994
Ensembl chr 2:107,986,523...108,013,994 		JBrowse link
G SLC6A12 solute carrier family 6 member 12 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SLC6A12 mRNA CTD PMID:27935865 NCBI chr12:183,848...214,157
Ensembl chr12:190,077...214,570 		JBrowse link
G SLC6A15 solute carrier family 6 member 15 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC6A15 mRNA CTD PMID:27935865 NCBI chr12:84,859,491...84,912,799
Ensembl chr12:84,859,491...84,913,629 		JBrowse link
G SLC6A17 solute carrier family 6 member 17 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC6A17 mRNA CTD PMID:27935865 NCBI chr 1:110,150,494...110,202,202
Ensembl chr 1:110,150,494...110,202,202 		JBrowse link
G SLC7A11 solute carrier family 7 member 11 increases expression EXP Pioglitazone results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349 		JBrowse link
G SLCO1B1 solute carrier organic anion transporter family member 1B1 multiple interactions EXP Pioglitazone inhibits the reaction [SLCO1B1 protein results in increased uptake of Atorvastatin] CTD PMID:23121773 NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 multiple interactions EXP pioglitazone affects the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein] CTD PMID:23121773 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SLCO2B1 solute carrier organic anion transporter family member 2B1 multiple interactions EXP pioglitazone affects the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein] CTD PMID:23121773 NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549 		JBrowse link
G SLCO4C1 solute carrier organic anion transporter family member 4C1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLCO4C1 mRNA CTD PMID:27935865 NCBI chr 5:102,233,986...102,296,284
Ensembl chr 5:102,233,986...102,296,284 		JBrowse link
G SLCO5A1 solute carrier organic anion transporter family member 5A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLCO5A1 mRNA CTD PMID:27935865 NCBI chr 8:69,667,046...69,834,978
Ensembl chr 8:69,667,046...69,834,978 		JBrowse link
G SLIT1 slit guidance ligand 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SLIT1 mRNA CTD PMID:27935865 NCBI chr10:96,998,038...97,185,959
Ensembl chr10:96,998,038...97,185,959 		JBrowse link
G SLN sarcolipin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLN mRNA CTD PMID:27935865 NCBI chr11:107,707,378...107,712,056
Ensembl chr11:107,707,378...107,719,693 		JBrowse link
G SLTM SAFB like transcription modulator multiple interactions EXP pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of SLTM mRNA] CTD PMID:20847119 NCBI chr15:58,879,050...58,933,679
Ensembl chr15:58,879,050...58,933,679 		JBrowse link
G SMAD9 SMAD family member 9 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SMAD9 mRNA CTD PMID:27935865 NCBI chr13:36,844,831...36,920,854
Ensembl chr13:36,844,831...36,920,887 		JBrowse link
G SMIM10L2A small integral membrane protein 10 like 2A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of SMIM10L2A mRNA CTD PMID:27935865 NCBI chr  X:135,421,944...135,428,075
Ensembl chr  X:135,421,944...135,428,075 		JBrowse link
G SMOC1 SPARC related modular calcium binding 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SMOC1 mRNA CTD PMID:27935865 NCBI chr14:69,879,416...70,032,366
Ensembl chr14:69,854,131...70,032,366 		JBrowse link
G SMPX small muscle protein X-linked multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SMPX mRNA CTD PMID:27935865 NCBI chr  X:21,705,978...21,758,116
Ensembl chr  X:21,705,978...21,758,116 		JBrowse link
G SMTNL1 smoothelin like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SMTNL1 mRNA CTD PMID:27935865 NCBI chr11:57,537,595...57,550,272
Ensembl chr11:57,537,595...57,550,272 		JBrowse link
G SNCAIP synuclein alpha interacting protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SNCAIP mRNA CTD PMID:27935865 NCBI chr 5:122,311,353...122,464,219
Ensembl chr 5:122,311,354...122,464,219 		JBrowse link
G SOD1 superoxide dismutase 1 increases expression
multiple interactions		 EXP
ISO		 pioglitazone results in increased expression of SOD1 mRNA; pioglitazone results in increased expression of SOD1 protein
pioglitazone inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in decreased expression of SOD1 mRNA]		 CTD PMID:11172467 PMID:18513333 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 affects activity ISO pioglitazone affects the activity of SOD2 protein CTD PMID:21962020 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SORCS1 sortilin related VPS10 domain containing receptor 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SORCS1 mRNA CTD PMID:27935865 NCBI chr10:106,573,663...107,181,138
Ensembl chr10:106,573,663...107,164,706 		JBrowse link
G SOWAHC sosondowah ankyrin repeat domain family member C increases expression EXP Pioglitazone results in increased expression of SOWAHC mRNA CTD PMID:30031879 NCBI chr 2:109,614,364...109,618,990
Ensembl chr 2:109,614,364...109,618,990 		JBrowse link
G SOX10 SRY-box transcription factor 10 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SOX10 mRNA CTD PMID:27935865 NCBI chr22:37,972,312...37,984,555
Ensembl chr22:37,970,686...37,987,422 		JBrowse link
G SOX8 SRY-box transcription factor 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SOX8 mRNA CTD PMID:27935865 NCBI chr16:981,770...986,979
Ensembl chr16:981,444...986,979 		JBrowse link
G SP7 Sp7 transcription factor multiple interactions ISO Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] CTD PMID:32473317 NCBI chr12:53,326,575...53,344,793
Ensembl chr12:53,326,575...53,345,315 		JBrowse link
G SPARCL1 SPARC like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SPARCL1 mRNA CTD PMID:27935865 NCBI chr 4:87,473,335...87,529,376
Ensembl chr 4:87,473,335...87,531,061 		JBrowse link
G SPEG striated muscle enriched protein kinase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SPEG mRNA CTD PMID:27935865 NCBI chr 2:219,434,843...219,493,629
Ensembl chr 2:219,434,843...219,493,629 		JBrowse link
G SPINK9 serine peptidase inhibitor Kazal type 9 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPINK12 mRNA CTD PMID:27935865 NCBI chr 5:148,321,305...148,339,852
Ensembl chr 5:148,321,203...148,339,852 		JBrowse link
G SPMIP11 sperm microtubule inner protein 11 increases expression ISO Pioglitazone results in increased expression of NPHS1 mRNA; Pioglitazone results in increased expression of NPHS1 protein CTD PMID:16687628 NCBI chr12:48,727,435...48,771,459
Ensembl chr12:48,727,435...48,765,790 		JBrowse link
G SPOCD1 SPOC domain containing 1 increases expression EXP Pioglitazone results in increased expression of SPOCD1 mRNA CTD PMID:30031879 NCBI chr 1:31,790,422...31,816,022
Ensembl chr 1:31,790,422...31,816,022 		JBrowse link
G SPON1 spondin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SPON1 mRNA CTD PMID:27935865 NCBI chr11:13,962,723...14,268,133
Ensembl chr11:13,962,723...14,268,133 		JBrowse link
G SPP1 secreted phosphoprotein 1 multiple interactions ISO pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 protein] CTD PMID:16979161 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SPRR1B small proline rich protein 1B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPRR1B mRNA CTD PMID:27935865 NCBI chr 1:153,031,203...153,032,900
Ensembl chr 1:153,031,203...153,032,900 		JBrowse link
G SPRR2A small proline rich protein 2A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of SPRR2H mRNA CTD PMID:27935865 NCBI chr 1:153,056,120...153,057,512
Ensembl chr 1:153,056,120...153,057,512 		JBrowse link
G SPRR2B small proline rich protein 2B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPRR2B mRNA CTD PMID:27935865 NCBI chr 1:153,070,226...153,087,799
Ensembl chr 1:153,070,226...153,071,611 		JBrowse link
G SPRR2D small proline rich protein 2D multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPRR2D mRNA CTD PMID:27935865 NCBI chr 1:153,039,732...153,041,120
Ensembl chr 1:153,039,732...153,041,931 		JBrowse link
G SPRR2E small proline rich protein 2E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPRR2E mRNA CTD PMID:27935865 NCBI chr 1:153,093,135...153,094,526
Ensembl chr 1:153,093,135...153,106,184 		JBrowse link
G SPRR2F small proline rich protein 2F multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPRR2F mRNA CTD PMID:27935865 NCBI chr 1:153,112,121...153,119,468
Ensembl chr 1:153,112,121...153,113,516 		JBrowse link
G SPRR2G small proline rich protein 2G multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of SPRR2G mRNA CTD PMID:27935865 NCBI chr 1:153,149,582...153,203,278
Ensembl chr 1:153,149,582...153,150,890 		JBrowse link
G SRL sarcalumenin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SRL mRNA CTD PMID:27935865 NCBI chr16:4,189,374...4,242,080
Ensembl chr16:4,189,374...4,242,080 		JBrowse link
G SRPX sushi repeat containing protein X-linked multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SRPX mRNA CTD PMID:27935865 NCBI chr  X:38,149,339...38,220,871
Ensembl chr  X:38,149,336...38,220,924 		JBrowse link
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ST3GAL1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ST3GAL1 mRNA] CTD PMID:20847119 NCBI chr 8:133,454,848...133,571,887
Ensembl chr 8:133,454,848...133,571,926 		JBrowse link
G STAC3 SH3 and cysteine rich domain 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of STAC3 mRNA CTD PMID:27935865 NCBI chr12:57,243,458...57,251,187
Ensembl chr12:57,243,453...57,251,188 		JBrowse link
G STK11 serine/threonine kinase 11 increases expression EXP Pioglitazone results in increased expression of STK11 mRNA CTD PMID:32589349 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G STX1B syntaxin 1B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of STX1B mRNA CTD PMID:27935865 NCBI chr16:30,989,256...31,010,638
Ensembl chr16:30,989,256...31,010,638 		JBrowse link
G STYXL2 serine/threonine/tyrosine interacting like 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of STYXL2 mRNA CTD PMID:27935865 NCBI chr 1:167,094,075...167,129,165
Ensembl chr 1:167,094,075...167,129,165 		JBrowse link
G SULT1C2 sulfotransferase family 1C member 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SULT1C2 mRNA CTD PMID:27935865 NCBI chr 2:108,288,895...108,309,915
Ensembl chr 2:108,288,639...108,309,915 		JBrowse link
G SULT1C3 sulfotransferase family 1C member 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SULT1C1 mRNA CTD PMID:27935865 NCBI chr 2:108,239,968...108,265,351
Ensembl chr 2:108,239,968...108,265,351 		JBrowse link
G SUSD5 sushi domain containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SUSD5 mRNA CTD PMID:27935865 NCBI chr 3:33,150,043...33,218,810
Ensembl chr 3:33,150,043...33,218,810 		JBrowse link
G SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SVEP1 mRNA CTD PMID:27935865 NCBI chr 9:110,365,248...110,579,741
Ensembl chr 9:110,365,248...110,579,880 		JBrowse link
G SVOPL SVOP like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SVOPL mRNA CTD PMID:27935865 NCBI chr 7:138,594,285...138,701,362
Ensembl chr 7:138,594,285...138,701,362 		JBrowse link
G SYN1 synapsin I multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SYN1 mRNA CTD PMID:27935865 NCBI chr  X:47,571,901...47,619,857
Ensembl chr  X:47,571,901...47,619,857 		JBrowse link
G SYN2 synapsin II multiple interactions ISO Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SYN2 protein] CTD PMID:32735850 NCBI chr 3:12,004,388...12,192,032
Ensembl chr 3:12,004,388...12,192,032 		JBrowse link
G SYNPO2 synaptopodin 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SYNPO2 mRNA CTD PMID:27935865 NCBI chr 4:118,850,681...119,061,247
Ensembl chr 4:118,850,688...119,061,247 		JBrowse link
G SYPL2 synaptophysin like 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SYPL2 mRNA CTD PMID:27935865 NCBI chr 1:109,466,546...109,482,134
Ensembl chr 1:109,466,546...109,482,134 		JBrowse link
G TAGLN transgelin multiple interactions
decreases expression		 ISO
EXP		 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TAGLN mRNA
Pioglitazone results in decreased expression of TAGLN mRNA		 CTD PMID:27935865 PMID:30031879 NCBI chr11:117,199,294...117,207,465
Ensembl chr11:117,199,370...117,207,464 		JBrowse link
G TARM1 T cell-interacting, activating receptor on myeloid cells 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TARM1 mRNA CTD PMID:27935865 NCBI chr19:54,069,895...54,081,365
Ensembl chr19:54,069,895...54,081,365 		JBrowse link
G TAS2R4 taste 2 receptor member 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TAS2R108 mRNA CTD PMID:27935865 NCBI chr 7:141,776,674...141,781,691
Ensembl chr 7:141,776,674...141,781,691 		JBrowse link
G TBX15 T-box transcription factor 15 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TBX15 mRNA CTD PMID:27935865 NCBI chr 1:118,883,047...118,989,510
Ensembl chr 1:118,883,046...118,989,556 		JBrowse link
G TBX4 T-box transcription factor 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TBX4 mRNA CTD PMID:27935865 NCBI chr17:61,452,422...61,485,110
Ensembl chr17:61,452,404...61,485,110 		JBrowse link
G TCAP titin-cap multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TCAP mRNA CTD PMID:27935865 NCBI chr17:39,665,349...39,666,554
Ensembl chr17:39,665,349...39,666,554 		JBrowse link
G TCEAL7 transcription elongation factor A like 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TCEAL7 mRNA CTD PMID:27935865 NCBI chr  X:103,330,239...103,332,326
Ensembl chr  X:103,330,229...103,332,326 		JBrowse link
G TDH L-threonine dehydrogenase (pseudogene) multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TDH mRNA CTD PMID:27935865 NCBI chr 8:11,339,637...11,368,452
Ensembl chr 8:11,339,637...11,368,452
Ensembl chr 8:11,339,637...11,368,452 		JBrowse link
G TDO2 tryptophan 2,3-dioxygenase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TDO2 mRNA CTD PMID:27935865 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406 		JBrowse link
G TELO2 telomere maintenance 2 increases expression
multiple interactions		 EXP Pioglitazone results in increased expression of TELO2 mRNA
[Metformin co-treated with Pioglitazone] results in increased expression of TELO2 mRNA		 CTD PMID:32589349 NCBI chr16:1,493,360...1,510,454
Ensembl chr16:1,493,344...1,510,457 		JBrowse link
G TET1 tet methylcytosine dioxygenase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TET1 mRNA CTD PMID:27935865 NCBI chr10:68,560,337...68,694,487
Ensembl chr10:68,560,337...68,694,487 		JBrowse link
G TFAM transcription factor A, mitochondrial decreases expression EXP pioglitazone results in decreased expression of TFAM mRNA CTD PMID:20860658 NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220 		JBrowse link
G TFF2 trefoil factor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TFF2 mRNA CTD PMID:27935865 NCBI chr21:42,346,357...42,350,994
Ensembl chr21:42,346,357...42,350,997 		JBrowse link
G TG thyroglobulin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TG mRNA CTD PMID:27935865 NCBI chr 8:132,866,958...133,134,899
Ensembl chr 8:132,866,958...133,134,903 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions
decreases expression		 ISO
EXP		 pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of TGFB1 protein]
Pioglitazone inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]
pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; pioglitazone inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; pioglitazone inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA]
pioglitazone results in decreased expression of TGFB1 mRNA		 CTD PMID:12055599 PMID:16484506 PMID:16611854 PMID:17015710 PMID:32613381 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGM7 transglutaminase 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TGM7 mRNA CTD PMID:27935865 NCBI chr15:43,276,271...43,302,255
Ensembl chr15:43,276,271...43,302,255 		JBrowse link
G THBS1 thrombospondin 1 multiple interactions ISO pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 protein] CTD PMID:17063547 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466 		JBrowse link
G THRSP thyroid hormone responsive multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of THRSP mRNA CTD PMID:27935865 NCBI chr11:78,063,861...78,068,351
Ensembl chr11:78,063,861...78,068,351 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:16484506 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TLE6 TLE family member 6, subcortical maternal complex member increases expression EXP Pioglitazone results in increased expression of TLE6 mRNA CTD PMID:30031879 NCBI chr19:2,977,401...2,995,179
Ensembl chr19:2,977,538...2,995,179 		JBrowse link
G TM4SF19 transmembrane 4 L six family member 19 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TM4SF19 mRNA CTD PMID:27935865 NCBI chr 3:196,323,547...196,338,388
Ensembl chr 3:196,319,342...196,338,503 		JBrowse link
G TMEM132C transmembrane protein 132C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TMEM132C mRNA CTD PMID:27935865 NCBI chr12:128,267,170...128,707,911
Ensembl chr12:128,267,170...128,707,911 		JBrowse link
G TMEM177 transmembrane protein 177 multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of TMEM177 mRNA CTD PMID:20847119 NCBI chr 2:119,679,201...119,723,618
Ensembl chr 2:119,679,167...119,686,507 		JBrowse link
G TMEM182 transmembrane protein 182 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TMEM182 mRNA CTD PMID:27935865 NCBI chr 2:102,736,935...102,843,838
Ensembl chr 2:102,736,905...103,019,900 		JBrowse link
G TMEM200B transmembrane protein 200B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TMEM200B mRNA CTD PMID:27935865 NCBI chr 1:29,119,429...29,123,903
Ensembl chr 1:29,119,429...29,123,903 		JBrowse link
G TMEM213 transmembrane protein 213 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TMEM213 mRNA CTD PMID:27935865 NCBI chr 7:138,797,994...138,806,759
Ensembl chr 7:138,797,952...138,838,101 		JBrowse link
G TMEM252 transmembrane protein 252 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TMEM252 mRNA CTD PMID:27935865 NCBI chr 9:68,536,580...68,540,883
Ensembl chr 9:68,536,580...68,540,883 		JBrowse link
G TMEM91 transmembrane protein 91 increases expression EXP Pioglitazone results in increased expression of TMEM91 mRNA CTD PMID:30031879 NCBI chr19:41,363,947...41,384,083
Ensembl chr19:41,350,911...41,384,083 		JBrowse link
G TMOD1 tropomodulin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TMOD1 mRNA CTD PMID:27935865 NCBI chr 9:97,501,180...97,601,743
Ensembl chr 9:97,501,180...97,601,743 		JBrowse link
G TMOD4 tropomodulin 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TMOD4 mRNA CTD PMID:27935865 NCBI chr 1:151,169,987...151,175,981
Ensembl chr 1:151,169,986...151,176,284 		JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases expression
affects expression		 EXP
ISO		 Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of and results in increased activity of BACE1 protein]; Pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Pioglitazone inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIB protein]
Pioglitazone results in decreased expression of TNF mRNA
pioglitazone affects the expression of TNF protein
[Pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of TNF mRNA; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased expression of TNF mRNA]
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of TNF protein]]; [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of TNF mRNA]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of TNF protein]]; Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; Pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Cisplatin results in increased expression of TNF mRNA]; Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Fructose results in increased secretion of TNF protein]; Pioglitazone inhibits the reaction [propionic acid results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of TNF mRNA]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]]		 CTD PMID:14586007 PMID:15318101 PMID:17055343 PMID:20450929 PMID:22989705 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP6 TNF alpha induced protein 6 increases expression EXP Pioglitazone results in increased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b multiple interactions EXP Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein] CTD PMID:31016361 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B increases secretion ISO Pioglitazone results in increased secretion of TNFRSF1B protein CTD PMID:27918843 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TNNC2 troponin C2, fast skeletal type multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TNNC2 mRNA CTD PMID:27935865 NCBI chr20:45,823,214...45,833,306
Ensembl chr20:45,823,214...45,833,745 		JBrowse link
G TNNI2 troponin I2, fast skeletal type multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TNNI2 mRNA CTD PMID:27935865 NCBI chr11:1,838,981...1,841,678
Ensembl chr11:1,838,981...1,841,680 		JBrowse link
G TNNT1 troponin T1, slow skeletal type multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TNNT1 mRNA CTD PMID:27935865 NCBI chr19:55,132,698...55,149,206
Ensembl chr19:55,132,698...55,149,206 		JBrowse link
G TNNT3 troponin T3, fast skeletal type multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TNNT3 mRNA CTD PMID:27935865 NCBI chr11:1,919,552...1,938,702
Ensembl chr11:1,919,703...1,938,706 		JBrowse link
G TPI1 triosephosphate isomerase 1 decreases expression ISO pioglitazone results in decreased expression of TPI1 mRNA CTD PMID:20723549 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948 		JBrowse link
G TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of TRARG1 mRNA CTD PMID:27935865 NCBI chr17:1,279,662...1,300,978
Ensembl chr17:1,279,662...1,300,978 		JBrowse link
G TRDN triadin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TRDN mRNA CTD PMID:27935865 NCBI chr 6:123,216,339...123,636,950
Ensembl chr 6:123,216,339...123,637,189 		JBrowse link
G TREML1 triggering receptor expressed on myeloid cells like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TREML1 mRNA CTD PMID:27935865 NCBI chr 6:41,149,260...41,155,403
Ensembl chr 6:41,149,337...41,154,347 		JBrowse link
G TRIB3 tribbles pseudokinase 3 decreases expression
multiple interactions		 EXP Pioglitazone results in decreased expression of TRIB3 mRNA
Pioglitazone inhibits the reaction [Arsenic Trioxide results in increased expression of TRIB3 mRNA]		 CTD PMID:32929351 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559 		JBrowse link
G TRIL TLR4 interactor with leucine rich repeats multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TRIL mRNA CTD PMID:27935865 NCBI chr 7:28,953,358...28,958,330
Ensembl chr 7:28,953,358...28,958,330 		JBrowse link
G TRIM54 tripartite motif containing 54 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TRIM54 mRNA CTD PMID:27935865 NCBI chr 2:27,282,429...27,307,435
Ensembl chr 2:27,282,429...27,307,439 		JBrowse link
G TRPC3 transient receptor potential cation channel subfamily C member 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TRPC3 mRNA CTD PMID:27935865 NCBI chr 4:121,874,481...121,952,060
Ensembl chr 4:121,874,481...121,952,060 		JBrowse link
G TTC41P tetratricopeptide repeat domain 41, pseudogene multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TTC41 mRNA CTD PMID:27935865 NCBI chr12:103,843,749...103,930,211
Ensembl chr12:103,843,756...103,915,867 		JBrowse link
G TTN titin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TTN mRNA CTD PMID:27935865 NCBI chr 2:178,525,989...178,807,423
Ensembl chr 2:178,525,989...178,830,802 		JBrowse link
G TUBB3 tubulin beta 3 class III multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TUBB3 mRNA CTD PMID:27935865 NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761 		JBrowse link
G TXLNB taxilin beta multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TXLNB mRNA CTD PMID:27935865 NCBI chr 6:139,159,162...139,323,950
Ensembl chr 6:139,240,061...139,291,998 		JBrowse link
G UBE2U ubiquitin conjugating enzyme E2 U multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of UBE2U mRNA CTD PMID:27935865 NCBI chr 1:64,203,623...64,267,368
Ensembl chr 1:64,203,623...64,267,368 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP Pioglitazone results in increased expression of UGT1A1 mRNA CTD PMID:31233785 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 multiple interactions
increases expression		 EXP [Metformin co-treated with Pioglitazone] results in increased expression of ULK1 mRNA
Pioglitazone results in increased expression of ULK1 mRNA		 CTD PMID:32589349 NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150 		JBrowse link
G ULK2 unc-51 like autophagy activating kinase 2 increases expression EXP Pioglitazone results in increased expression of ULK2 mRNA CTD PMID:32589349 NCBI chr17:19,770,830...19,867,936
Ensembl chr17:19,770,829...19,867,936 		JBrowse link
G UMPS uridine monophosphate synthetase multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of UMPS mRNA CTD PMID:20847119 NCBI chr 3:124,730,452...124,749,273
Ensembl chr 3:124,730,433...124,749,273 		JBrowse link
G UNC45B unc-45 myosin chaperone B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of UNC45B mRNA CTD PMID:27935865 NCBI chr17:35,147,817...35,189,345
Ensembl chr17:35,147,817...35,189,345 		JBrowse link
G USP13 ubiquitin specific peptidase 13 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of USP13 mRNA CTD PMID:27935865 NCBI chr 3:179,653,040...179,789,401
Ensembl chr 3:179,653,032...179,804,366 		JBrowse link
G VASN vasorin multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of VASN mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of VASN mRNA] CTD PMID:20847119 NCBI chr16:4,371,848...4,383,538
Ensembl chr16:4,371,848...4,383,538 		JBrowse link
G VAT1L vesicle amine transport 1 like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of VAT1L mRNA CTD PMID:27935865 NCBI chr16:77,788,564...77,980,107
Ensembl chr16:77,788,564...77,980,107 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions ISO pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of VCAM1 protein]
Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of VCAM1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]		 CTD PMID:16979161 PMID:17015710 PMID:30343038 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions
increases expression
decreases expression		 EXP
ISO		 [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of VEGFA mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of VEGFA mRNA]
Pioglitazone results in increased expression of VEGFA mRNA
pioglitazone inhibits the reaction [Dietary Fats results in increased expression of VEGFA mRNA]
pioglitazone results in decreased expression of VEGFA protein		 CTD PMID:20847119 PMID:22456468 PMID:26281317 PMID:32589349 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VEGFB vascular endothelial growth factor B increases expression EXP Pioglitazone results in increased expression of VEGFB mRNA CTD PMID:32589349 NCBI chr11:64,234,584...64,239,264
Ensembl chr11:64,234,584...64,239,264 		JBrowse link
G VLDLR very low density lipoprotein receptor increases expression ISO
EXP		 pioglitazone results in increased expression of VLDLR mRNA
Pioglitazone results in increased expression of VLDLR mRNA		 CTD PMID:19706614 PMID:30031879 NCBI chr 9:2,621,787...2,660,056
Ensembl chr 9:2,621,182...2,660,056 		JBrowse link
G VTN vitronectin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of VTN mRNA CTD PMID:27935865 NCBI chr17:28,367,284...28,370,307
Ensembl chr17:28,367,284...28,373,091 		JBrowse link
G VWA2 von Willebrand factor A domain containing 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of VWA2 mRNA CTD PMID:27935865 NCBI chr10:114,239,254...114,294,500
Ensembl chr10:114,239,254...114,294,489 		JBrowse link
G WFDC13 WAP four-disulfide core domain 13 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of WFDC13 mRNA CTD PMID:27935865 NCBI chr20:45,702,038...45,708,817
Ensembl chr20:45,702,038...45,708,817 		JBrowse link
G WNT2B Wnt family member 2B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of WNT2B mRNA CTD PMID:27935865 NCBI chr 1:112,466,541...112,530,165
Ensembl chr 1:112,466,541...112,530,165 		JBrowse link
G WSCD2 WSC domain containing 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of WSCD2 mRNA CTD PMID:27935865 NCBI chr12:108,129,288...108,250,537
Ensembl chr12:108,129,288...108,250,537 		JBrowse link
G XCR1 X-C motif chemokine receptor 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of XCR1 mRNA CTD PMID:27935865 NCBI chr 3:46,017,007...46,085,844
Ensembl chr 3:46,016,990...46,085,825 		JBrowse link
G XIRP1 xin actin binding repeat containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of XIRP1 mRNA CTD PMID:27935865 NCBI chr 3:39,183,215...39,192,595
Ensembl chr 3:39,183,210...39,192,596 		JBrowse link
G XIRP2 xin actin binding repeat containing 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of XIRP2 mRNA CTD PMID:27935865 NCBI chr 2:166,888,480...167,259,753
Ensembl chr 2:166,888,480...167,259,753 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 multiple interactions ISO Pioglitazone inhibits the reaction [LEPR protein affects the expression of XRCC1 protein] CTD PMID:35472412 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
G YIPF7 Yip1 domain family member 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of YIPF7 mRNA CTD PMID:27935865 NCBI chr 4:44,622,088...44,662,199
Ensembl chr 4:44,622,088...44,678,556 		JBrowse link
G ZC3H11A zinc finger CCCH-type containing 11A multiple interactions EXP pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ZC3H11A mRNA] CTD PMID:20847119 NCBI chr 1:203,795,623...203,854,124
Ensembl chr 1:203,795,623...203,854,999 		JBrowse link
G ZCCHC18 zinc finger CCHC-type containing 18 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZCCHC18 mRNA CTD PMID:27935865 NCBI chr  X:104,112,523...104,115,842
Ensembl chr  X:104,112,131...104,115,842 		JBrowse link
G ZCWPW1 zinc finger CW-type and PWWP domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZCWPW1 mRNA CTD PMID:27935865 NCBI chr 7:100,400,872...100,428,703
Ensembl chr 7:100,400,826...100,428,992 		JBrowse link
G ZDBF2 zinc finger DBF-type containing 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZDBF2 mRNA CTD PMID:27935865 NCBI chr 2:206,274,663...206,314,427
Ensembl chr 2:206,274,663...206,314,427 		JBrowse link
G ZFP36 ZFP36 ring finger protein multiple interactions EXP [pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ZFP36 mRNA CTD PMID:20847119 NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,412 		JBrowse link
G ZKSCAN4 zinc finger with KRAB and SCAN domains 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZKSCAN4 mRNA CTD PMID:27935865 NCBI chr 6:28,241,697...28,259,211
Ensembl chr 6:28,241,697...28,252,269 		JBrowse link
G ZNF117 zinc finger protein 117 multiple interactions EXP Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ZNF117 mRNA] CTD PMID:20847119 NCBI chr 7:64,971,772...64,991,036
Ensembl chr 7:64,971,772...65,006,684 		JBrowse link
G ZNF354C zinc finger protein 354C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZFP354C mRNA CTD PMID:27935865 NCBI chr 5:179,060,373...179,083,977
Ensembl chr 5:179,060,373...179,083,977 		JBrowse link
G ZNF385C zinc finger protein 385C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZFP385C mRNA CTD PMID:27935865 NCBI chr17:42,025,576...42,098,473
Ensembl chr17:42,025,576...42,098,479 		JBrowse link
G ZNF454 zinc finger protein 454 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZFP454 mRNA CTD PMID:27935865 NCBI chr 5:178,941,198...178,990,028
Ensembl chr 5:178,941,191...178,966,433 		JBrowse link
G ZNF521 zinc finger protein 521 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZFP521 mRNA CTD PMID:27935865 NCBI chr18:25,061,924...25,352,166
Ensembl chr18:25,061,924...25,352,190 		JBrowse link
G ZNF641 zinc finger protein 641 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZFP641 mRNA CTD PMID:27935865 NCBI chr12:48,334,587...48,351,246
Ensembl chr12:48,337,180...48,351,414 		JBrowse link
G ZNF681 zinc finger protein 681 multiple interactions EXP pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ZNF681 mRNA] CTD PMID:20847119 NCBI chr19:23,739,195...23,758,891
Ensembl chr19:23,739,195...23,758,891 		JBrowse link
G ZPBP zona pellucida binding protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZPBP mRNA CTD PMID:27935865 NCBI chr 7:49,840,654...50,093,246
Ensembl chr 7:49,850,421...50,121,329 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26041
    role 25957
      biological role 25936
        xenobiotic 20368
          pioglitazone 768
            hydroxypioglitazone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26041
    subatomic particle 26016
      composite particle 26016
        hadron 26016
          baryon 26016
            nucleon 26016
              atomic nucleus 26016
                atom 26016
                  main group element atom 25841
                    p-block element atom 25841
                      carbon group element atom 25441
                        carbon atom 25399
                          organic molecular entity 25399
                            organic molecule 25228
                              organic cyclic compound 24281
                                organic heterocyclic compound 22324
                                  organic heteromonocyclic compound 19228
                                    thiazolidines 8659
                                      thiazolidinediones 780
                                        pioglitazone 768
                                          hydroxypioglitazone 0
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