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Gene: APOC2 (apolipoprotein C2) Homo sapiens
Symbol: APOC2
Name: apolipoprotein C2
Description: Exhibits several functions, including enzyme regulator activity; phospholipase binding activity; and protein homodimerization activity. Involved in several processes, including lipid transport; positive regulation of lipase activity; and regulation of lipid metabolic process. Localizes to several cellular components, including the low-density lipoprotein particle; spherical high-density lipoprotein particle; and triglyceride-rich plasma lipoprotein particle. Implicated in familial hyperlipidemia; familial lipoprotein lipase deficiency; and multiple sclerosis. Biomarker of diabetes mellitus (multiple); end stage renal failure; hypobetalipoproteinemia; nephrotic syndrome; and obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APO-CII; APOC-II; apolipoprotein C-II; MGC75082
Mus musculus (house mouse) : Apoc2 (apolipoprotein C-II)  MGI  Alliance
Rattus norvegicus (Norway rat) : Apoc2 (apolipoprotein C2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apoc2 (apolipoprotein C2)
Pan paniscus (bonobo/pygmy chimpanzee) : APOC2 (apolipoprotein C2)
Canis lupus familiaris (dog) : APOC2 (apolipoprotein C2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apoc2 (apolipoprotein C2)
Sus scrofa (pig) : APOC2 (apolipoprotein C2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381944,946,051 - 44,949,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371945,449,239 - 45,452,822 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,141,083 - 50,144,658 (+)NCBINCBI36hg18NCBI36
Build 341950,141,082 - 50,144,657NCBI
Celera1942,253,565 - 42,257,132 (+)NCBI
Cytogenetic Map19q13.32NCBI
HuRef1941,879,798 - 41,883,381 (+)NCBIHuRef
CHM1_11945,452,071 - 45,455,660 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on APOC2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1352001
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.