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Gene: CDC42 (cell division cycle 42) Homo sapiens
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Symbol: CDC42
Name: cell division cycle 42
Description: Exhibits several functions, including GBD domain binding activity; GTP binding activity; and enzyme binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of cellular component organization; and regulation of cell cycle process. Localizes to several cellular components, including the Golgi transport complex; midbody; and spindle. Colocalizes with the centrosome. Implicated in fibrosarcoma. Biomarker of Alzheimer's disease; bipolar disorder; pancreatic cancer; and rhinitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDC42Hs; cell division control protein 42 homolog; cell division cycle 42 (GTP binding protein, 25kDa); dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); G25K; G25K GTP-binding protein; growth-regulating protein; GTP binding protein, 25kDa; GTP-binding protein, 25kD; small GTP binding protein CDC42; TKS
Orthologs:
Mus musculus (house mouse) : Cdc42 (cell division cycle 42)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdc42 (cell division cycle 42)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc42 (cell division cycle 42)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC42 (cell division cycle 42)
Canis lupus familiaris (dog) : CDC42 (cell division cycle 42)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc42 (cell division cycle 42)
Sus scrofa (pig) : CDC42 (cell division cycle 42)
Chlorocebus sabaeus (African green monkey) : CDC42 (cell division cycle 42)
Heterocephalus glaber (naked mole-rat) : Cdc42 (cell division cycle 42)
more info ...
Related Pseudogenes: CDC42P1   CDC42P2   CDC42P3   CDC42P4   CDC42P5   CDC42P6  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl122,025,511 - 22,101,360 (+)EnsemblGRCh38hg38GRCh38
GRCh38122,052,709 - 22,101,360 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37122,379,120 - 22,419,439 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,251,707 - 22,292,023 (+)NCBINCBI36hg18NCBI36
Build 34122,124,487 - 22,164,741NCBI
Celera120,702,109 - 20,742,389 (+)NCBI
Cytogenetic Map1p36.12NCBI
HuRef120,622,960 - 20,663,212 (+)NCBIHuRef
CHM1_1122,491,651 - 22,531,931 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on CDC42
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730976
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.