GWAS1146176_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1146176_H (uterine fibroid QTL GWAS1146176 (human)) Homo sapiens

Symbol: GWAS1146176_H
Name: uterine fibroid QTL GWAS1146176 (human)
RGD ID: 597050102
Trait: uterine fibroid
LOD Score: Not Available
P Value: 3.0E-7
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38122,096,228 - 22,096,229RGD_MAPPER_PIPELINEGRCh38
GRCh37122,422,721 - 22,422,722RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1146176_HHumanuterine fibroid  IAGPrs10917151405850206 GWAS_CATALOGPMID:31488892

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1146176_HHumanUterine leiomyoma  IAGPrs10917151405850206 GWAS_CATALOGPMID:31488892
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1146176_HHumanuterine fibroid  IAGPrs10917151405850206 GWAS_CATALOGPMID:31488892

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
730976CDC42cell division cycle 4212205270922101360Human


Peak: (rs10917151)
Human AssemblyChrPosition (strand)Source
GRCh38122,096,228 - 22,096,229RGD_MAPPER_PIPELINE


1 to 10 of 12 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
597050102GWAS1146176_Huterine fibroid QTL GWAS1146176 (human)0.0000003uterine fibroid12209622822096229Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597096436GWAS1192510_Huterine fibroid QTL GWAS1192510 (human)5e-14uterine fibroid12209622822096229Human
597212381GWAS1308455_Huterine fibroid QTL GWAS1308455 (human)2e-24uterine fibroid12209622822096229Human
597050304GWAS1146378_Huterine fibroid QTL GWAS1146378 (human)5e-12uterine fibroid12209622822096229Human
597149087GWAS1245161_Hfemale infertility, endometriosis QTL GWAS1245161 (human)0.0000002female infertility, endometriosis12209622822096229Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
597149563GWAS1245637_Hendometriosis QTL GWAS1245637 (human)5e-44endometriosis12209622822096229Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human

1 to 10 of 12 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1146176_H GCST009833 Uterine fibroids (MTAG) 5,236 Japanese ancestry cases, 39,556 Japanese ancestry controls ? NR 3E-7 6.523 rs10917151 1.03 uterine fibroid (EFO:0000731)
 PMID:31488892
GWAS1146378_H GCST009834 Uterine fibroids 5,236 Japanese ancestry cases, 39,556 Japanese ancestry controls ? NR 5E-12 11.302 rs10917151 1.14 uterine fibroid (EFO:0000731)
 PMID:31488892
GWAS1192510_H GCST006462 Uterine fibroids 16,595 European ancestry cases, 523,330 European ancestry controls A 0.20124 5E-14 13.302 rs10917151 1.12 uterine fibroid (EFO:0000731)
 PMID:30194396
GWAS1245154_H GCST90258639 Endometriosis (stage 3 or 4) 4,045 European ancestry cases, 379,890 European ancestry controls A 0.17 5E-11 10.302 rs10917151 1.23 endometriosis (EFO:0001065)
 PMID:36914876
GWAS1245161_H GCST90258641 Endometriosis-associated infertility 3,060 European ancestry cases, 242,555 European ancestry controls A 0.17 2E-7 6.699 rs10917151 1.21 female infertility (EFO:0008560)
endometriosis (EFO:0001065)
 PMID:36914876
GWAS1245637_H GCST90258638 Endometriosis 58,961 European ancestry cases, 700,345 European ancestry controls, 1,713 Japanese ancestry cases, 1,581 Japanese ancestry controls A NR 5E-44 43.302 rs10917151 1.14 endometriosis (EFO:0001065)
 PMID:36914876
GWAS1308455_H GCST008423 Uterine fibroids 8,168 European ancestry cases, 65,134 European ancestry controls, 1,278 African ancestry cases, 1,914 African ancestry controls A 0.16 2E-24 23.699 rs10917151 1.16 uterine fibroid (EFO:0000731)
 PMID:31249589
Database
Acc Id
Source(s)
GWAS Catalog GCST009833 GWAS Catalog

Note Type Note Reference