Gene: LOC403934 (cell division cycle 42) Canis lupus familiaris

Analyze

Symbol:

LOC403934 (Ensembl: CDC42)

Name:

cell division cycle 42

RGD ID:

12349424

Description:

ENCODES a protein that exhibits apolipoprotein A-I receptor binding (ortholog); GBD domain binding (ortholog); GTP binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament branching (ortholog); actin filament organization (ortholog); PARTICIPATES IN adenosine signaling pathway; c-Jun N-terminal kinases MAPK signaling pathway; E-cadherin signaling pathway; ASSOCIATED WITH Adrenal Gland Neoplasms (ortholog); Alzheimer's disease (ortholog); anemia (ortholog); FOUND IN apical part of cell (ortholog); cell leading edge (ortholog); cell-cell junction (ortholog)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CDC42; CDC42 GTP-binding protein; cell division control protein 42 homolog; cell division cycle 42 (GTP binding protein, 25kDa); G25K GTP-binding protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CDC42 (cell division cycle 42)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Cdc42 (cell division cycle 42)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Cdc42 (cell division cycle 42)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cdc42 (cell division cycle 42)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CDC42 (cell division cycle 42)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cdc42 (cell division cycle 42)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CDC42 (cell division cycle 42)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CDC42 (cell division cycle 42)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cdc42 (cell division cycle 42)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cdc42 (cell division cycle 42)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	77,153,276 - 77,169,947 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	77,153,095 - 77,199,211 (-)	Ensembl		CanFam3.1 Ensembl	canFam3	CanFam3.1
ROS_Cfam_1.0	4	4,445,564 - 4,446,293 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	4	4,457,005 - 4,457,734 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	4,574,515 - 4,575,244 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	4,796,130 - 4,796,859 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Adrenal Gland Neoplasms (ISO)

Alzheimer's disease (ISO)

anemia (ISO)

Animal Mammary Neoplasms (ISO)

bipolar disorder (ISO)

carcinoma (ISO)

cholangiocarcinoma (ISO)

cleft palate (ISO)

clubfoot (ISO)

congenital heart disease (ISO)

epilepsy (ISO)

Epistaxis (ISO)

exanthem (ISO)

Experimental Arthritis (ISO)

Experimental Mammary Neoplasms (ISO)

Failure to Thrive (ISO)

Familial Hemophagocytic Lymphohistiocytoses (ISO)

Fever (ISO)

fibrosarcoma (ISO)

genetic disease (ISO)

head and neck squamous cell carcinoma (ISO)

hepatocellular carcinoma (ISO)

human immunodeficiency virus infectious disease (ISO)

hydronephrosis (ISO)

intellectual disability (ISO)

Intracranial Hemorrhages (ISO)

Lethargy (ISO)

lung cancer (ISO)

microvillus inclusion disease (ISO)

Necrosis (ISO)

Neurodevelopmental Disorders (ISO)

nonpapillary renal cell carcinoma (ISO)

Nuchal Bleb, Familial (ISO)

ovarian serous cystadenocarcinoma (ISO)

pancreatic cancer (ISO)

pathologic nystagmus (ISO)

Pyelectasis (ISO)

Reperfusion Injury (ISO)

rhinitis (ISO)

sarcoma (ISO)

Single Umbilical Artery (ISO)

Spinal Cord Injuries (ISO)

Splenomegaly (ISO)

stomach cancer (ISO)

Takenouchi-Kosaki Syndrome (ISO)

temporal lobe epilepsy (ISO)

thrombocytopenia (ISO)

thymoma (ISO)

uterine corpus endometrial carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (ISO)

actin filament branching (ISO)

actin filament organization (IBA,ISO,ISS)

adherens junction organization (ISO)

anatomical structure morphogenesis (IEA)

cardiac conduction system development (ISO)

cardiac neural crest cell migration involved in outflow tract morphogenesis (ISO)

cell junction assembly (ISS)

cellular response to type II interferon (ISO)

dendritic cell migration (ISO)

dendritic spine morphogenesis (ISS)

embryonic heart tube development (ISO)

endocytosis (IBA,ISO)

endothelin receptor signaling pathway (ISO)

establishment of cell polarity (IBA)

establishment of epithelial cell apical/basal polarity (ISS)

establishment of Golgi localization (ISO)

establishment or maintenance of apical/basal cell polarity (ISO)

filopodium assembly (ISO)

Golgi organization (ISO)

heart contraction (ISO)

heart process (ISO)

integrin-mediated signaling pathway (ISO)

intracellular protein localization (ISO)

negative regulation of protein-containing complex assembly (ISO)

neuron fate determination (ISO)

neuropilin signaling pathway (ISO)

nuclear migration (ISO)

nucleus localization (ISO)

organelle transport along microtubule (ISO)

phagocytosis, engulfment (ISS)

positive regulation of catalytic activity (ISO)

positive regulation of cell growth (ISO)

positive regulation of cell migration (ISO)

positive regulation of cellular component organization (IEA)

positive regulation of cytokinesis (ISS)

positive regulation of DNA replication (ISO)

positive regulation of epithelial cell proliferation involved in lung morphogenesis (ISO)

positive regulation of filopodium assembly (ISS)

positive regulation of intracellular protein transport (ISO)

positive regulation of JNK cascade (ISO)

positive regulation of lamellipodium assembly (ISO)

positive regulation of MAPK cascade (ISO)

positive regulation of neuron apoptotic process (ISO)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

positive regulation of pinocytosis (ISS)

positive regulation of pseudopodium assembly (ISO)

positive regulation of stress fiber assembly (ISO)

positive regulation of substrate adhesion-dependent cell spreading (ISS)

positive regulation of synapse structural plasticity (ISO)

protein phosphorylation (ISO)

regulation of actin cytoskeleton organization (ISO)

regulation of attachment of spindle microtubules to kinetochore (ISS)

regulation of filopodium assembly (IBA,ISS)

regulation of lamellipodium assembly (ISO)

regulation of mitotic nuclear division (ISO)

regulation of modification of postsynaptic structure (ISO)

regulation of postsynapse organization (ISO)

regulation of stress fiber assembly (ISO)

signal transduction (IBA)

sprouting angiogenesis (ISO)

submandibular salivary gland formation (ISO)

substantia nigra development (ISO)

Cellular Component

acrosomal vesicle (IEA)

apical part of cell (ISO)

cell leading edge (ISO)

cell periphery (IEA)

cell-cell junction (ISO)

centrosome (IEA)

COG complex (ISO)

cytoplasm (IEA,ISS)

cytoplasmic ribonucleoprotein granule (ISO)

cytosol (ISO)

dendrite (IEA)

filopodium (ISO)

glutamatergic synapse (ISO)

Golgi membrane (ISO)

lamellipodium membrane (IEA)

leading edge membrane (ISO)

membrane (ISS)

microtubule cytoskeleton (ISO)

midbody (IEA,ISS)

mitotic spindle (ISS)

neuron projection (ISO)

neuronal cell body (ISO)

phagocytic vesicle (ISO)

plasma membrane (IBA,IEA,ISS)

postsynapse (ISO)

protein-containing complex (ISO)

Schaffer collateral - CA1 synapse (ISO)

secretory granule (ISO)

spindle (IEA)

spindle midzone (ISS)

storage vacuole (ISO)

Molecular Function

apolipoprotein A-I receptor binding (ISO)

G protein activity (IEA)

GBD domain binding (ISO)

GTP binding (IBA,IEA,ISO)

GTP-dependent protein binding (ISO)

GTPase activity (IBA,IEA,ISS)

identical protein binding (ISO)

mitogen-activated protein kinase kinase kinase binding (ISO)

protein binding (ISO)

protein kinase binding (IBA,IEA)

thioesterase binding (ISO)

ubiquitin protein ligase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

adenosine signaling pathway (ISO)

c-Jun N-terminal kinases MAPK signaling pathway (ISO)

E-cadherin signaling pathway (ISO)

endothelin signaling pathway (ISO)

ephrin - ephrin receptor bidirectional signaling axis (ISO)

insulin secretion pathway (ISO)

N-cadherin signaling pathway (ISO)

p38 MAPK signaling pathway (ISO)

Rho/Rac/Cdc42 mediated signaling pathway (ISO)

sphingosine 1-phosphate signaling pathway (ISO)

vascular endothelial growth factor signaling pathway (ISO)

Wnt signaling, non-canonical pathway (ISO)

References

Additional References at PubMed

PMID:15093747	PMID:15456777	PMID:15834156	PMID:17098962	PMID:22301074	PMID:27901125	PMID:28554775	PMID:30032202

Genomics

Comparative Map Data

LOC403934
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	77,153,276 - 77,169,947 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	77,153,095 - 77,199,211 (-)	Ensembl		CanFam3.1 Ensembl	canFam3	CanFam3.1
ROS_Cfam_1.0	4	4,445,564 - 4,446,293 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	4	4,457,005 - 4,457,734 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	4,574,515 - 4,575,244 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	4,796,130 - 4,796,859 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

CDC42
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	22,052,709 - 22,101,360 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	22,052,627 - 22,101,360 (+)	Ensembl		GRCh38.p14 Ensembl	hg38	GRCh38
GRCh37	1	22,379,202 - 22,427,853 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	22,251,707 - 22,292,023 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	22,124,487 - 22,164,741	NCBI
Celera	1	20,702,109 - 20,742,389 (+)	NCBI		Celera
Cytogenetic Map	1	p36.12	NCBI
HuRef	1	20,622,960 - 20,663,212 (+)	NCBI		HuRef
CHM1_1	1	22,491,651 - 22,531,931 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	21,876,517 - 21,925,101 (+)	NCBI		T2T-CHM13v2.0

Cdc42
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	137,047,011 - 137,085,007 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	137,047,002 - 137,101,278 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	137,319,696 - 137,357,759 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	137,319,696 - 137,357,720 (-)	Ensembl		GRCm38.p6 Ensembl	mm10	GRCm38
MGSCv37	4	136,875,611 - 136,913,652 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	136,591,779 - 136,608,205 (-)	NCBI		MGSCv36	mm8
Celera	4	135,540,002 - 135,577,854 (-)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	69.83	NCBI

Cdc42
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	154,838,478 - 154,876,629 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	154,839,631 - 154,876,627 (-)	Ensembl				GRCr8
mRatBN7.2	5	149,555,069 - 149,593,239 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	149,553,724 - 149,593,111 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	152,253,400 - 152,289,928 (-)	NCBI	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	154,027,699 - 154,064,227 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	154,009,694 - 154,046,226 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	5	154,458,897 - 154,495,386 (-)	NCBI
Lyon_Normotensive	5	156,447,664 - 156,484,153 (-)	NCBI
Lyon_Hypertensive	5	155,624,644 - 155,661,134 (-)	NCBI
F344_StmMcwi	5	149,194,943 - 149,231,435 (-)	NCBI
Rnor_6.0	5	155,690,267 - 155,728,385 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	155,691,390 - 155,728,300 (-)	Ensembl		Rnor_6.0 Ensembl	rn6	Rnor6.0
Rnor_5.0	5	159,446,154 - 159,485,163 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	156,106,123 - 156,143,040 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	147,953,334 - 147,989,998 (-)	NCBI		Celera
RGSC_v3.1	5	156,116,164 - 156,153,079 (-)	NCBI
Cytogenetic Map	5	q36	NCBI

Cdc42
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	2,255,117 - 2,299,042 (+)	Ensembl		ChiLan1.0 Ensembl
ChiLan1.0	NW_004955452	2,255,940 - 2,299,042 (+)	NCBI	ChiLan1.0	ChiLan1.0

CDC42
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	204,846,790 - 204,887,042 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	203,958,664 - 203,998,887 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	21,245,970 - 21,286,210 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	22,188,722 - 22,228,351 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

Cdc42
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mIctTri1.hap1	11	14,504,478 - 14,546,614 (+)	NCBI		mIctTri1.hap1
HiC_Itri_2	NW_024405058	41,731,950 - 41,773,901 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	7,556,728 - 7,598,761 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	7,556,765 - 7,598,687 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDC42
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	80,035,123 - 80,089,233 (+)	Ensembl		Sscrofa11.1 Ensembl	susScr11	Sscrofa11.1
Sscrofa11.1	6	80,035,034 - 80,089,243 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	74,057,184 - 74,116,824 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDC42
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mChlSab1.0.hap1	20	114,977,887 - 115,017,703 (-)	NCBI		mChlSab1.0.hap1
Vero_WHO_p1.0	NW_023666033	5,689,907 - 5,730,175 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0
ChlSab1.1	20	110,568,004 - 110,608,318 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	110,569,352 - 110,582,562 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

Cdc42
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624764	6,874,453 - 6,891,952 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2
Naked mole-rat maternal Ensembl	7	27,376,888 - 27,428,533 (-)	Ensembl

Cdc42
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	20,859,956 - 20,878,384 (+)	NCBI	Rrattus_CSIRO_v1	Rrattus_CSIRO_v1

Variants

Variants in LOC403934
126 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001003254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001389221	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	DN353664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DN371418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000023350 ⟹ ENSCAFP00000021683

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	77,153,095 - 77,199,195 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000023351 ⟹ ENSCAFP00000021684

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	77,154,524 - 77,199,211 (-)	Ensembl

RefSeq Acc Id:

NM_001389221 ⟹ NP_001376150

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	4	4,445,564 - 4,446,293 (+)	NCBI
UMICH_Zoey_3.1	4	4,457,005 - 4,457,734 (+)	NCBI
UNSW_CanFamBas_1.0	4	4,574,515 - 4,575,244 (+)	NCBI
UU_Cfam_GSD_1.0	4	4,796,130 - 4,796,859 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001376150	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00845004474
	ENSCAFP00845004474.1
	ENSCAFP00845025242.1

Ensembl Acc Id:

ENSCAFP00000021684 ⟸ ENSCAFT00000023351

Ensembl Acc Id:

ENSCAFP00000021683 ⟸ ENSCAFT00000023350

RefSeq Acc Id:	NP_001376150 ⟸ NM_001389221
- UniProtKB:	P60952 (UniProtKB/Swiss-Prot), A0A8I3P5T9 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000014707	Ensembl
	ENSCAFG00845003209	ENTREZGENE, UniProtKB/TrEMBL
	ENSCAFG00845018261	UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00845005638	ENTREZGENE
	ENSCAFT00845005638.1	UniProtKB/TrEMBL
	ENSCAFT00845032290.1	UniProtKB/TrEMBL
Gene3D-CATH	P-loop containing nucleotide triphosphate hydrolases	UniProtKB/TrEMBL
InterPro	Cdc42	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Small_GTP-bd	UniProtKB/TrEMBL
	Small_GTPase	UniProtKB/TrEMBL
	Small_GTPase_Rho	UniProtKB/TrEMBL
NCBI Gene	CDC42	ENTREZGENE
PANTHER	RHO FAMILY GTPASE	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
SMART	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	P-loop containing nucleoside triphosphate hydrolases	UniProtKB/TrEMBL
UniProt	A0A8I3MRX7_CANLF	UniProtKB/TrEMBL
	A0A8I3P5T9	ENTREZGENE, UniProtKB/TrEMBL
	P60952	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-01-12	LOC403934	cell division cycle 42	CDC42	cell division cycle 42	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)