CDC42 (cell division cycle 42) - Rat Genome Database

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Gene: CDC42 (cell division cycle 42) Pan paniscus
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Symbol: CDC42
Name: cell division cycle 42
RGD ID: 11761240
Description: ENCODES a protein that exhibits apolipoprotein A-I receptor binding (ortholog); GBD domain binding (ortholog); GTP binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament branching (ortholog); actin filament organization (ortholog); PARTICIPATES IN adenosine signaling pathway; c-Jun N-terminal kinases MAPK signaling pathway; E-cadherin signaling pathway; ASSOCIATED WITH Adrenal Gland Neoplasms (ortholog); Alzheimer's disease (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN apical part of cell (ortholog); cell leading edge (ortholog); cell periphery (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: cell division control protein 42 homolog; cell division cycle 42 (GTP binding protein, 25kDa)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1122,188,722 - 22,228,351 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0121,245,970 - 21,286,210 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (ISO)
actin filament branching  (ISO)
actin filament organization  (ISO)
adherens junction organization  (ISO)
cardiac conduction system development  (ISO)
cardiac neural crest cell migration involved in outflow tract morphogenesis  (ISO)
Cdc42 protein signal transduction  (ISO)
cell junction assembly  (ISO)
cellular protein localization  (ISO)
cellular response to interferon-gamma  (ISO)
dendritic cell migration  (ISO)
dendritic spine morphogenesis  (ISO)
embryonic heart tube development  (ISO)
endocytosis  (ISO)
endothelin receptor signaling pathway involved in heart process  (ISO)
establishment of epithelial cell apical/basal polarity  (ISO)
establishment of Golgi localization  (ISO)
establishment or maintenance of apical/basal cell polarity  (ISO)
filopodium assembly  (ISO)
Golgi organization  (ISO)
heart contraction  (ISO)
integrin-mediated signaling pathway  (ISO)
modification of synaptic structure  (ISO)
negative regulation of protein-containing complex assembly  (ISO)
neuron fate determination  (ISO)
neuropilin signaling pathway  (ISO)
nuclear migration  (ISO)
nucleus localization  (ISO)
organelle transport along microtubule  (ISO)
phagocytosis, engulfment  (ISO)
positive regulation of actin cytoskeleton reorganization  (ISO)
positive regulation of catalytic activity  (ISO)
positive regulation of cell growth  (ISO)
positive regulation of cytokinesis  (ISO)
positive regulation of DNA replication  (ISO)
positive regulation of epithelial cell proliferation involved in lung morphogenesis  (ISO)
positive regulation of filopodium assembly  (ISO)
positive regulation of intracellular protein transport  (ISO)
positive regulation of JNK cascade  (ISO)
positive regulation of lamellipodium assembly  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of phosphatidylinositol 3-kinase activity  (ISO)
positive regulation of pinocytosis  (ISO)
positive regulation of pseudopodium assembly  (ISO)
positive regulation of stress fiber assembly  (ISO)
positive regulation of substrate adhesion-dependent cell spreading  (ISO)
positive regulation of synapse structural plasticity  (ISO)
protein phosphorylation  (ISO)
regulation of attachment of spindle microtubules to kinetochore  (ISO)
regulation of filopodium assembly  (ISO)
regulation of lamellipodium assembly  (ISO)
regulation of mitotic nuclear division  (ISO)
regulation of modification of postsynaptic structure  (ISO)
regulation of protein binding  (ISO)
regulation of stress fiber assembly  (ISO)
sprouting angiogenesis  (ISO)
submandibular salivary gland formation  (ISO)
substantia nigra development  (ISO)
viral RNA genome replication  (ISO)

References

Genomics

Comparative Map Data
CDC42
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1122,188,722 - 22,228,351 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0121,245,970 - 21,286,210 (+)NCBIMhudiblu_PPA_v0panPan3
CDC42
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl122,025,511 - 22,101,360 (+)EnsemblGRCh38hg38GRCh38
GRCh38122,052,709 - 22,101,360 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37122,379,202 - 22,427,853 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,251,707 - 22,292,023 (+)NCBINCBI36hg18NCBI36
Build 34122,124,487 - 22,164,741NCBI
Celera120,702,109 - 20,742,389 (+)NCBI
Cytogenetic Map1p36.12NCBI
HuRef120,622,960 - 20,663,212 (+)NCBIHuRef
CHM1_1122,491,651 - 22,531,931 (+)NCBICHM1_1
Cdc42
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394137,047,007 - 137,085,070 (-)NCBIGRCm39mm39
GRCm39 Ensembl4137,047,007 - 137,085,031 (-)Ensembl
GRCm384137,319,696 - 137,357,759 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4137,319,696 - 137,357,720 (-)EnsemblGRCm38mm10GRCm38
MGSCv374136,875,611 - 136,913,652 (-)NCBIGRCm37mm9NCBIm37
MGSCv364136,591,779 - 136,608,205 (-)NCBImm8
Celera4135,540,002 - 135,577,854 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map469.83NCBI
Cdc42
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25149,555,069 - 149,593,239 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl5149,553,724 - 149,593,111 (-)Ensembl
Rnor_6.05155,690,267 - 155,728,385 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5155,691,390 - 155,728,300 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05159,446,154 - 159,485,163 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45156,106,123 - 156,143,040 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15156,116,164 - 156,153,079 (-)NCBI
Celera5147,953,334 - 147,989,998 (-)NCBICelera
Cytogenetic Map5q36NCBI
Cdc42
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554522,255,117 - 2,299,042 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554522,255,940 - 2,299,042 (+)NCBIChiLan1.0ChiLan1.0
LOC403934
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1277,153,276 - 77,169,947 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl277,153,095 - 77,199,211 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.044,445,564 - 4,446,293 (+)NCBI
UMICH_Zoey_3.144,457,005 - 4,457,734 (+)NCBI
UNSW_CanFamBas_1.044,574,515 - 4,575,244 (+)NCBI
UU_Cfam_GSD_1.044,796,130 - 4,796,859 (+)NCBI
Cdc42
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505841,731,950 - 41,773,901 (+)NCBI
SpeTri2.0NW_0049364747,556,765 - 7,598,687 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC42
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl680,035,122 - 80,089,233 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1680,035,034 - 80,089,243 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2674,057,184 - 74,116,824 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDC42
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120110,568,004 - 110,608,318 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl20110,569,352 - 110,582,562 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660335,689,907 - 5,730,175 (+)NCBIVero_WHO_p1.0
Cdc42
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247646,874,453 - 6,891,952 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_003813957   ⟹   XP_003814005
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1122,188,722 - 22,228,351 (+)NCBI
Mhudiblu_PPA_v0121,245,970 - 21,286,210 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003813960   ⟹   XP_003814008
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1122,188,722 - 22,226,231 (+)NCBI
Mhudiblu_PPA_v0121,245,970 - 21,284,085 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034957768   ⟹   XP_034813659
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0121,267,375 - 21,286,210 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003814005 (Get FASTA)   NCBI Sequence Viewer  
  XP_003814008 (Get FASTA)   NCBI Sequence Viewer  
  XP_034813659 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003814005   ⟸   XM_003813957
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003814008   ⟸   XM_003813960
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_034813659   ⟸   XM_034957768
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031108 ENTREZGENE
Ensembl Protein ENSPPAP00000015981 ENTREZGENE
  ENSPPAP00000015993 ENTREZGENE
NCBI Gene CDC42 ENTREZGENE