EPHA5 (EPH receptor A5) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: EPHA5 (EPH receptor A5) Homo sapiens
Analyze
Symbol: EPHA5
Name: EPH receptor A5
RGD ID: 1605127
HGNC Page HGNC:3389
Description: Predicted to enable GPI-linked ephrin receptor activity; growth factor binding activity; and transmembrane-ephrin receptor activity. Involved in neuron development. Located in several cellular components, including external side of plasma membrane; neuronal cell body; and rough endoplasmic reticulum.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: brain-specific kinase; CEK7; EHK-1; EHK1; EK7; EPH homology kinase 1; Eph homology kinase-1; EPH-like kinase 7; ephrin type-A receptor 5; HEK7; receptor protein-tyrosine kinase HEK7; TYRO4; tyrosine-protein kinase receptor EHK-1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38465,319,567 - 65,670,489 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl465,319,563 - 65,670,495 (-)EnsemblGRCh38hg38GRCh38
GRCh37466,185,285 - 66,536,207 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36465,872,241 - 66,218,104 (-)NCBINCBI36Build 36hg18NCBI36
Celera463,644,911 - 63,993,769 (-)NCBICelera
Cytogenetic Map4q13.1-q13.2NCBI
HuRef462,095,699 - 62,445,869 (-)NCBIHuRef
CHM1_1466,222,199 - 66,573,162 (-)NCBICHM1_1
T2T-CHM13v2.0468,756,500 - 69,108,844 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7528718   PMID:7898931   PMID:7973638   PMID:8755474   PMID:8889548   PMID:9191074   PMID:9267020   PMID:9321686   PMID:9321687   PMID:9530499   PMID:9576626   PMID:10064801  
PMID:10207129   PMID:10375373   PMID:10516308   PMID:10531456   PMID:10730216   PMID:11076863   PMID:11128993   PMID:11230166   PMID:11256076   PMID:12477932   PMID:15485908   PMID:15489336  
PMID:16381901   PMID:16737551   PMID:19036963   PMID:19733895   PMID:19949912   PMID:19953087   PMID:20379614   PMID:21873635   PMID:22079638   PMID:22174851   PMID:23824631   PMID:24029132  
PMID:24086308   PMID:25609195   PMID:25623065   PMID:26186194   PMID:27582484   PMID:27651378   PMID:27887627   PMID:27988259   PMID:28065597   PMID:28421649   PMID:28514442   PMID:30561431  
PMID:30898150   PMID:31586073   PMID:31823378   PMID:31871319   PMID:32234341   PMID:32707033   PMID:33288738   PMID:33961781   PMID:34109382   PMID:35332588   PMID:35384245   PMID:36164608  
PMID:36345952  


Genomics

Comparative Map Data
EPHA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38465,319,567 - 65,670,489 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl465,319,563 - 65,670,495 (-)EnsemblGRCh38hg38GRCh38
GRCh37466,185,285 - 66,536,207 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36465,872,241 - 66,218,104 (-)NCBINCBI36Build 36hg18NCBI36
Celera463,644,911 - 63,993,769 (-)NCBICelera
Cytogenetic Map4q13.1-q13.2NCBI
HuRef462,095,699 - 62,445,869 (-)NCBIHuRef
CHM1_1466,222,199 - 66,573,162 (-)NCBICHM1_1
T2T-CHM13v2.0468,756,500 - 69,108,844 (-)NCBIT2T-CHM13v2.0
Epha5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39584,199,024 - 84,565,677 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl584,202,620 - 84,565,241 (-)EnsemblGRCm39 Ensembl
GRCm38584,054,761 - 84,417,818 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl584,054,761 - 84,417,382 (-)EnsemblGRCm38mm10GRCm38
MGSCv37584,483,786 - 84,846,407 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36585,132,352 - 85,491,482 (-)NCBIMGSCv36mm8
Celera581,291,528 - 81,651,176 (-)NCBICelera
Cytogenetic Map5E1NCBI
cM Map543.0NCBI
Epha5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81424,007,400 - 24,374,854 (+)NCBIGRCr8
mRatBN7.21423,653,393 - 24,020,129 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1423,653,393 - 24,017,317 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1423,956,543 - 24,317,814 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01425,268,992 - 25,630,263 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01423,801,211 - 24,162,478 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01425,589,312 - 25,958,258 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1425,589,762 - 25,958,227 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01425,417,590 - 25,788,026 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41425,524,170 - 25,896,798 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11425,256,413 - 25,884,513 (+)NCBI
Celera1423,059,394 - 23,424,647 (+)NCBICelera
Cytogenetic Map14p21NCBI
Epha5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554477,066,111 - 7,382,046 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554477,066,111 - 7,382,046 (+)NCBIChiLan1.0ChiLan1.0
EPHA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2364,222,358 - 64,574,467 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1464,447,417 - 64,799,360 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0458,392,771 - 58,743,604 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1464,767,083 - 65,113,510 (+)NCBIpanpan1.1PanPan1.1panPan2
EPHA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11356,054,247 - 56,402,583 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1356,058,800 - 56,383,301 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1355,969,239 - 56,314,376 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01356,669,158 - 57,015,552 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1356,671,834 - 57,016,808 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11356,388,025 - 56,733,358 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01355,892,815 - 56,238,437 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01356,885,964 - 57,231,303 (-)NCBIUU_Cfam_GSD_1.0
Epha5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528519,941,499 - 20,271,236 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365822,505,145 - 2,830,014 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365822,503,546 - 2,832,950 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPHA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl863,287,711 - 63,604,734 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1863,285,006 - 63,604,734 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2867,246,392 - 67,540,677 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPHA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.173,219,396 - 3,564,416 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl73,219,449 - 3,559,854 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660663,415,672 - 3,777,756 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Epha5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247613,693,540 - 4,048,953 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247613,693,462 - 4,050,426 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EPHA5
47 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 4q12-13.2(chr4:51831622-66991489)x3 copy number gain See cases [RCV000051771] Chr4:51831622..66991489 [GRCh38]
Chr4:52697788..67857207 [GRCh37]
Chr4:52392545..67539802 [NCBI36]
Chr4:4q12-13.2		 pathogenic
GRCh38/hg38 4q12-22.3(chr4:51831622-97505618)x3 copy number gain See cases [RCV000051772] Chr4:51831622..97505618 [GRCh38]
Chr4:52697788..98426769 [GRCh37]
Chr4:52392545..98645792 [NCBI36]
Chr4:4q12-22.3		 pathogenic
GRCh38/hg38 4q13.1-13.3(chr4:65454562-72313693)x1 copy number loss See cases [RCV000053293] Chr4:65454562..72313693 [GRCh38]
Chr4:66320280..73179410 [GRCh37]
Chr4:66002875..73398274 [NCBI36]
Chr4:4q13.1-13.3		 pathogenic
NM_004439.6(EPHA5):c.236C>T (p.Pro79Leu) single nucleotide variant Malignant melanoma [RCV000066475] Chr4:65643373 [GRCh38]
Chr4:66509091 [GRCh37]
Chr4:66191686 [NCBI36]
Chr4:4q13.2		 not provided
NM_001281765.1(EPHA5):c.911-43568C>A single nucleotide variant Lung cancer [RCV000094986] Chr4:65539111 [GRCh38]
Chr4:66404829 [GRCh37]
Chr4:4q13.2		 uncertain significance
NM_001281765.1(EPHA5):c.246+10937C>T single nucleotide variant Lung cancer [RCV000094987] Chr4:65632426 [GRCh38]
Chr4:66498144 [GRCh37]
Chr4:4q13.2		 uncertain significance
GRCh38/hg38 4q13.1-13.2(chr4:63868950-65648341)x1 copy number loss See cases [RCV000141369] Chr4:63868950..65648341 [GRCh38]
Chr4:64734668..66514059 [GRCh37]
Chr4:64417263..66196654 [NCBI36]
Chr4:4q13.1-13.2		 uncertain significance
NM_001281766.3(EPHA5):c.1043A>G (p.Asp348Gly) single nucleotide variant Astrocytoma [RCV000599116] Chr4:65495411 [GRCh38]
Chr4:66361129 [GRCh37]
Chr4:4q13.1		 uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q13.1-13.2(chr4:65649502-67200024)x1 copy number loss See cases [RCV000447609] Chr4:65649502..67200024 [GRCh37]
Chr4:4q13.1-13.2		 uncertain significance
NM_001281766.3(EPHA5):c.1748G>A (p.Gly583Glu) single nucleotide variant Lung adenocarcinoma [RCV000432246] Chr4:65404419 [GRCh38]
Chr4:66270137 [GRCh37]
Chr4:4q13.1		 likely pathogenic
GRCh37/hg19 4q13.1-21.1(chr4:66017575-76772947)x1 copy number loss See cases [RCV000510445] Chr4:66017575..76772947 [GRCh37]
Chr4:4q13.1-21.1		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q13.1-13.2(chr4:65999842-67635149)x1 copy number loss See cases [RCV000511506] Chr4:65999842..67635149 [GRCh37]
Chr4:4q13.1-13.2		 uncertain significance
GRCh37/hg19 4q13.1(chr4:64717781-66524890)x1 copy number loss See cases [RCV000511204] Chr4:64717781..66524890 [GRCh37]
Chr4:4q13.1		 likely benign
GRCh37/hg19 4p16.3-q13.1(chr4:68345-66440622)x3 copy number gain See cases [RCV000511193] Chr4:68345..66440622 [GRCh37]
Chr4:4p16.3-q13.1		 pathogenic
GRCh37/hg19 4q13.1(chr4:65991029-66411150) copy number loss Global developmental delay [RCV000626535] Chr4:65991029..66411150 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.3037A>T (p.Met1013Leu) single nucleotide variant Inborn genetic diseases [RCV003311018] Chr4:65324128 [GRCh38]
Chr4:66189846 [GRCh37]
Chr4:4q13.1		 uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q13.1-13.3(chr4:64705501-73469716)x3 copy number gain not provided [RCV000682409] Chr4:64705501..73469716 [GRCh37]
Chr4:4q13.1-13.3		 pathogenic
GRCh37/hg19 4q13.1-13.2(chr4:65395609-69170853)x1 copy number loss not provided [RCV000682411] Chr4:65395609..69170853 [GRCh37]
Chr4:4q13.1-13.2		 uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q12-13.3(chr4:58332294-71587615)x1 copy number loss not provided [RCV000743602] Chr4:58332294..71587615 [GRCh37]
Chr4:4q12-13.3		 pathogenic
GRCh37/hg19 4q13.1-13.2(chr4:66509085-66628728)x3 copy number gain not provided [RCV000743642] Chr4:66509085..66628728 [GRCh37]
Chr4:4q13.1-13.2		 benign
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
NM_001281766.3(EPHA5):c.2235+4G>A single nucleotide variant not provided [RCV000970110] Chr4:65353038 [GRCh38]
Chr4:66218756 [GRCh37]
Chr4:4q13.1		 benign
NM_001281766.3(EPHA5):c.16C>T (p.Pro6Ser) single nucleotide variant Inborn genetic diseases [RCV003269816] Chr4:65669727 [GRCh38]
Chr4:66535445 [GRCh37]
Chr4:4q13.2		 uncertain significance
NM_001281766.3(EPHA5):c.537C>T (p.Ala179=) single nucleotide variant not provided [RCV000969189] Chr4:65602014 [GRCh38]
Chr4:66467732 [GRCh37]
Chr4:4q13.2		 benign
Single allele deletion Neurodevelopmental disorder [RCV000787447] Chr4:61605456..68762943 [GRCh37]
Chr4:4q13.1-13.2		 likely pathogenic
NM_001281766.3(EPHA5):c.2461A>G (p.Ile821Val) single nucleotide variant Inborn genetic diseases [RCV003292257] Chr4:65348188 [GRCh38]
Chr4:66213906 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.1582G>C (p.Glu528Gln) single nucleotide variant not provided [RCV000961531] Chr4:65414389 [GRCh38]
Chr4:66280107 [GRCh37]
Chr4:4q13.1		 benign
NM_001281766.3(EPHA5):c.2173+8T>A single nucleotide variant not provided [RCV000891384] Chr4:65365009 [GRCh38]
Chr4:66230727 [GRCh37]
Chr4:4q13.1		 benign
NM_001281766.3(EPHA5):c.1938T>C (p.Ala646=) single nucleotide variant not provided [RCV000889521] Chr4:65365981 [GRCh38]
Chr4:66231699 [GRCh37]
Chr4:4q13.1		 benign
NM_001281766.3(EPHA5):c.1954T>A (p.Ser652Thr) single nucleotide variant not provided [RCV000913054] Chr4:65365965 [GRCh38]
Chr4:66231683 [GRCh37]
Chr4:4q13.1		 likely benign
GRCh37/hg19 4q13.1-13.2(chr4:66215872-68647080)x1 copy number loss not provided [RCV002473432] Chr4:66215872..68647080 [GRCh37]
Chr4:4q13.1-13.2		 uncertain significance
GRCh37/hg19 4q13.1-13.2(chr4:65650283-66813883)x1 copy number loss not provided [RCV001259266] Chr4:65650283..66813883 [GRCh37]
Chr4:4q13.1-13.2		 uncertain significance
GRCh38/hg38 4q12-21.1(chr4:51891814-76009719)x1 copy number loss Piebaldism [RCV001420508] Chr4:51891814..76009719 [GRCh38]
Chr4:4q12-21.1		 pathogenic
GRCh37/hg19 4q12-31.21(chr4:52866944-143582507)x3 copy number gain not provided [RCV001827738] Chr4:52866944..143582507 [GRCh37]
Chr4:4q12-31.21		 pathogenic
GRCh37/hg19 4q13.1(chr4:65824021-66365406)x3 copy number gain not provided [RCV001827790] Chr4:65824021..66365406 [GRCh37]
Chr4:4q13.1		 uncertain significance
GRCh37/hg19 4q13.1-13.3(chr4:61867555-74711517) copy number loss not specified [RCV002053422] Chr4:61867555..74711517 [GRCh37]
Chr4:4q13.1-13.3		 pathogenic
NM_001281766.3(EPHA5):c.2536G>A (p.Val846Ile) single nucleotide variant Inborn genetic diseases [RCV003295438] Chr4:65348113 [GRCh38]
Chr4:66213831 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.958G>A (p.Gly320Ser) single nucleotide variant Inborn genetic diseases [RCV002685201] Chr4:65495496 [GRCh38]
Chr4:66361214 [GRCh37]
Chr4:4q13.1		 likely benign
NM_001281766.3(EPHA5):c.2212G>T (p.Gly738Cys) single nucleotide variant Inborn genetic diseases [RCV002752529] Chr4:65353065 [GRCh38]
Chr4:66218783 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.1571C>T (p.Thr524Ile) single nucleotide variant Inborn genetic diseases [RCV002818361] Chr4:65414400 [GRCh38]
Chr4:66280118 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.1297G>T (p.Ala433Ser) single nucleotide variant Inborn genetic diseases [RCV002860205] Chr4:65490482 [GRCh38]
Chr4:66356200 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.2812C>G (p.His938Asp) single nucleotide variant Inborn genetic diseases [RCV002754548] Chr4:65332106 [GRCh38]
Chr4:66197824 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.1423G>A (p.Val475Met) single nucleotide variant Inborn genetic diseases [RCV002840142] Chr4:65420545 [GRCh38]
Chr4:66286263 [GRCh37]
Chr4:4q13.1		 uncertain significance
GRCh37/hg19 4q13.1(chr4:65952175-66507443)x3 copy number gain not provided [RCV002475672] Chr4:65952175..66507443 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.992A>G (p.Glu331Gly) single nucleotide variant Inborn genetic diseases [RCV002696380] Chr4:65495462 [GRCh38]
Chr4:66361180 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.3034G>A (p.Gly1012Arg) single nucleotide variant Inborn genetic diseases [RCV002926160] Chr4:65324131 [GRCh38]
Chr4:66189849 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.10T>C (p.Ser4Pro) single nucleotide variant Inborn genetic diseases [RCV002693971] Chr4:65669733 [GRCh38]
Chr4:66535451 [GRCh37]
Chr4:4q13.2		 uncertain significance
NM_001281766.3(EPHA5):c.100G>A (p.Ala34Thr) single nucleotide variant Inborn genetic diseases [RCV002662193] Chr4:65669643 [GRCh38]
Chr4:66535361 [GRCh37]
Chr4:4q13.2		 uncertain significance
NM_001281766.3(EPHA5):c.1963A>T (p.Thr655Ser) single nucleotide variant Inborn genetic diseases [RCV002784451] Chr4:65365956 [GRCh38]
Chr4:66231674 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.2014C>T (p.Arg672Cys) single nucleotide variant Inborn genetic diseases [RCV002698491] Chr4:65365176 [GRCh38]
Chr4:66230894 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.1283T>C (p.Met428Thr) single nucleotide variant Inborn genetic diseases [RCV002892352] Chr4:65490496 [GRCh38]
Chr4:66356214 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.1412C>T (p.Pro471Leu) single nucleotide variant Inborn genetic diseases [RCV002714366] Chr4:65420556 [GRCh38]
Chr4:66286274 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.41C>A (p.Pro14His) single nucleotide variant Inborn genetic diseases [RCV002813921] Chr4:65669702 [GRCh38]
Chr4:66535420 [GRCh37]
Chr4:4q13.2		 uncertain significance
NM_001281766.3(EPHA5):c.1052C>G (p.Thr351Arg) single nucleotide variant Inborn genetic diseases [RCV003201300] Chr4:65495402 [GRCh38]
Chr4:66361120 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.1851T>A (p.His617Gln) single nucleotide variant Inborn genetic diseases [RCV003201431] Chr4:65367367 [GRCh38]
Chr4:66233085 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.1794-9635T>G single nucleotide variant Inborn genetic diseases [RCV003211685] Chr4:65377059 [GRCh38]
Chr4:66242777 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.148C>T (p.Leu50Phe) single nucleotide variant Inborn genetic diseases [RCV003181273] Chr4:65669595 [GRCh38]
Chr4:66535313 [GRCh37]
Chr4:4q13.2		 uncertain significance
NM_001281766.3(EPHA5):c.2974G>A (p.Val992Ile) single nucleotide variant Inborn genetic diseases [RCV003218681] Chr4:65324191 [GRCh38]
Chr4:66189909 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.1107T>A (p.Asn369Lys) single nucleotide variant Inborn genetic diseases [RCV003200594] Chr4:65490672 [GRCh38]
Chr4:66356390 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.91T>G (p.Cys31Gly) single nucleotide variant Inborn genetic diseases [RCV003360406] Chr4:65669652 [GRCh38]
Chr4:66535370 [GRCh37]
Chr4:4q13.2		 uncertain significance
NM_001281766.3(EPHA5):c.974A>G (p.His325Arg) single nucleotide variant Inborn genetic diseases [RCV003385487] Chr4:65495480 [GRCh38]
Chr4:66361198 [GRCh37]
Chr4:4q13.1		 uncertain significance
NM_001281766.3(EPHA5):c.1944G>T (p.Glu648Asp) single nucleotide variant Inborn genetic diseases [RCV003383095] Chr4:65365975 [GRCh38]
Chr4:66231693 [GRCh37]
Chr4:4q13.1		 uncertain significance
GRCh37/hg19 4q12-13.3(chr4:57584845-72430996)x1 copy number loss not provided [RCV003485417] Chr4:57584845..72430996 [GRCh37]
Chr4:4q12-13.3		 pathogenic
GRCh37/hg19 4q13.1-13.3(chr4:63684557-71480358)x3 copy number gain not provided [RCV003484182] Chr4:63684557..71480358 [GRCh37]
Chr4:4q13.1-13.3		 pathogenic
GRCh37/hg19 4q13.1-13.2(chr4:65293814-67567104)x1 copy number loss not provided [RCV003485421] Chr4:65293814..67567104 [GRCh37]
Chr4:4q13.1-13.2		 uncertain significance
GRCh37/hg19 4q13.1(chr4:65890760-66503982)x3 copy number gain not provided [RCV003484183] Chr4:65890760..66503982 [GRCh37]
Chr4:4q13.1		 uncertain significance
GRCh37/hg19 4q13.1-13.2(chr4:65646937-68662306)x3 copy number gain not specified [RCV003986482] Chr4:65646937..68662306 [GRCh37]
Chr4:4q13.1-13.2		 uncertain significance
GRCh37/hg19 4p12-q35.2(chr4:45455621-191003541)x3 copy number gain not provided [RCV003885507] Chr4:45455621..191003541 [GRCh37]
Chr4:4p12-q35.2		 pathogenic
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR34Ahsa-miR-34a-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI22079638
MIR34Ahsa-miR-34a-3pMirecordsexternal_infoNANA22079638

Predicted Target Of
Summary Value
Count of predictions:3089
Count of miRNA genes:915
Interacting mature miRNAs:1073
Transcripts:ENST00000273854, ENST00000354839, ENST00000432638, ENST00000511294
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D4S1574  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,241,364 - 66,241,553UniSTSGRCh37
GRCh37466,241,277 - 66,241,461UniSTSGRCh37
Build 36465,923,959 - 65,924,148RGDNCBI36
Celera463,700,894 - 63,701,078UniSTS
Celera463,700,981 - 63,701,170RGD
Cytogenetic Map4q13.1UniSTS
HuRef462,151,677 - 62,151,861UniSTS
HuRef462,151,764 - 62,151,953UniSTS
Marshfield Genetic Map475.2RGD
Marshfield Genetic Map475.2UniSTS
Genethon Genetic Map474.1UniSTS
deCODE Assembly Map478.12UniSTS
Whitehead-YAC Contig Map4 UniSTS
D4S2683  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,455,775 - 66,455,899UniSTSGRCh37
Build 36466,138,370 - 66,138,494RGDNCBI36
Celera463,913,837 - 63,913,961RGD
Cytogenetic Map4q13.1UniSTS
HuRef462,366,022 - 62,366,146UniSTS
TNG Radiation Hybrid Map436328.0UniSTS
Whitehead-YAC Contig Map4 UniSTS
STS-N22219  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,537,267 - 66,537,434UniSTSGRCh37
Build 36466,219,862 - 66,220,029RGDNCBI36
Celera463,995,387 - 63,995,554RGD
Cytogenetic Map4q13.1UniSTS
HuRef462,447,487 - 62,447,654UniSTS
TNG Radiation Hybrid Map436400.0UniSTS
GeneMap99-GB4 RH Map4389.31UniSTS
STS-N25770  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,346,015 - 66,346,161UniSTSGRCh37
Build 36466,028,610 - 66,028,756RGDNCBI36
Celera463,805,036 - 63,805,182RGD
Cytogenetic Map4q13.1UniSTS
HuRef462,256,425 - 62,256,571UniSTS
TNG Radiation Hybrid Map436170.0UniSTS
GeneMap99-GB4 RH Map4389.41UniSTS
RH119182  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,280,711 - 66,281,041UniSTSGRCh37
Build 36465,963,306 - 65,963,636RGDNCBI36
Celera463,740,329 - 63,740,659RGD
Cytogenetic Map4q13.1UniSTS
HuRef462,191,149 - 62,191,479UniSTS
TNG Radiation Hybrid Map436159.0UniSTS
SHGC-13970  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,416,353 - 66,416,662UniSTSGRCh37
Build 36466,098,948 - 66,099,257RGDNCBI36
Celera463,875,537 - 63,875,846RGD
Cytogenetic Map4q13.1UniSTS
HuRef462,326,657 - 62,326,966UniSTS
TNG Radiation Hybrid Map436187.0UniSTS
SHGC-8247  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,432,620 - 66,432,785UniSTSGRCh37
Build 36466,115,215 - 66,115,380RGDNCBI36
Celera463,891,841 - 63,892,006RGD
Cytogenetic Map4q13.1UniSTS
HuRef462,342,900 - 62,343,065UniSTS
TNG Radiation Hybrid Map436205.0UniSTS
SHGC-50222  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,189,680 - 66,189,802UniSTSGRCh37
Build 36465,872,275 - 65,872,397RGDNCBI36
Celera463,649,310 - 63,649,432RGD
Cytogenetic Map4q13.1UniSTS
HuRef462,100,098 - 62,100,220UniSTS
TNG Radiation Hybrid Map436155.0UniSTS
D4S3280  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,189,685 - 66,189,802UniSTSGRCh37
Build 36465,872,280 - 65,872,397RGDNCBI36
Celera463,649,315 - 63,649,432RGD
Cytogenetic Map4q13.1UniSTS
HuRef462,100,103 - 62,100,220UniSTS
SHGC-67256  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,189,680 - 66,189,816UniSTSGRCh37
Build 36465,872,275 - 65,872,411RGDNCBI36
Celera463,649,310 - 63,649,446RGD
Cytogenetic Map4q13.1UniSTS
HuRef462,100,098 - 62,100,234UniSTS
GeneMap99-GB4 RH Map4384.47UniSTS
RH45566  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,421,658 - 66,421,857UniSTSGRCh37
Build 36466,104,253 - 66,104,452RGDNCBI36
Celera463,880,832 - 63,881,031RGD
Cytogenetic Map4q13.1UniSTS
HuRef462,331,945 - 62,332,144UniSTS
GeneMap99-GB4 RH Map4381.08UniSTS
SHGC4-1516  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,494,042 - 66,494,226UniSTSGRCh37
Build 36466,176,637 - 66,176,821RGDNCBI36
Celera463,952,172 - 63,952,356RGD
Cytogenetic Map4q13.1UniSTS
HuRef462,404,360 - 62,404,544UniSTS
TNG Radiation Hybrid Map436367.0UniSTS
EPHA5  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37466,467,864 - 66,468,021UniSTSGRCh37
Celera463,925,935 - 63,926,092UniSTS
HuRef462,378,120 - 62,378,277UniSTS
D4S1574  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4q13.1UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 2 5 3 3 3 4 13 108 3 8 26
Low 165 159 803 55 22 9 739 54 2723 34 761 622 49 1 43 646 1
Below cutoff 2065 2171 450 191 612 77 3030 1684 891 127 507 732 115 1083 1744 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001281765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001281766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001281767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001318761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_004439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_182472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005265653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011531735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017007878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017007879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017007880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017007881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB209375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC018683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC104137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC105923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC115223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK307826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC136257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC136258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM664168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX537946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ901043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  H11658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L36644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000273854   ⟹   ENSP00000273854
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl465,319,563 - 65,670,343 (-)Ensembl
RefSeq Acc Id: ENST00000354839   ⟹   ENSP00000346899
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl465,323,928 - 65,669,935 (-)Ensembl
RefSeq Acc Id: ENST00000432638   ⟹   ENSP00000389208
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl465,323,395 - 65,670,060 (-)Ensembl
RefSeq Acc Id: ENST00000511294   ⟹   ENSP00000427638
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl465,330,561 - 65,670,495 (-)Ensembl
RefSeq Acc Id: ENST00000613740   ⟹   ENSP00000478537
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl465,319,567 - 65,670,489 (-)Ensembl
RefSeq Acc Id: ENST00000622150   ⟹   ENSP00000480763
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl465,319,563 - 65,670,495 (-)Ensembl
RefSeq Acc Id: NM_001281765   ⟹   NP_001268694
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,319,567 - 65,670,489 (-)NCBI
HuRef462,095,699 - 62,446,429 (-)NCBI
CHM1_1466,222,199 - 66,573,722 (-)NCBI
T2T-CHM13v2.0468,756,500 - 69,108,844 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001281766   ⟹   NP_001268695
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,319,567 - 65,670,489 (-)NCBI
HuRef462,095,699 - 62,446,429 (-)NCBI
CHM1_1466,222,199 - 66,573,722 (-)NCBI
T2T-CHM13v2.0468,756,500 - 69,108,844 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001281767   ⟹   NP_001268696
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,330,558 - 65,670,489 (-)NCBI
HuRef462,095,699 - 62,446,429 (-)NCBI
CHM1_1466,233,197 - 66,573,722 (-)NCBI
T2T-CHM13v2.0468,767,490 - 69,108,844 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001318761   ⟹   NP_001305690
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,319,567 - 65,669,488 (-)NCBI
CHM1_1466,222,199 - 66,572,715 (-)NCBI
T2T-CHM13v2.0468,756,500 - 69,107,843 (-)NCBI
Sequence:
RefSeq Acc Id: NM_004439   ⟹   NP_004430
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,319,567 - 65,670,489 (-)NCBI
GRCh37466,185,281 - 66,536,529 (-)NCBI
Build 36465,872,241 - 66,218,104 (-)NCBI Archive
HuRef462,095,699 - 62,446,429 (-)NCBI
CHM1_1466,222,199 - 66,573,722 (-)NCBI
T2T-CHM13v2.0468,756,500 - 69,108,844 (-)NCBI
Sequence:
RefSeq Acc Id: NM_182472   ⟹   NP_872272
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,319,567 - 65,670,489 (-)NCBI
GRCh37466,185,281 - 66,536,529 (-)NCBI
Build 36465,872,241 - 66,218,104 (-)NCBI Archive
HuRef462,095,699 - 62,446,429 (-)NCBI
CHM1_1466,222,199 - 66,573,722 (-)NCBI
T2T-CHM13v2.0468,756,500 - 69,108,844 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005265653   ⟹   XP_005265710
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,319,567 - 65,670,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011531735   ⟹   XP_011530037
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,319,567 - 65,670,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017007878   ⟹   XP_016863367
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,319,567 - 65,670,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017007880   ⟹   XP_016863369
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,319,567 - 65,670,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017007881   ⟹   XP_016863370
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,330,558 - 65,670,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047449762   ⟹   XP_047305718
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,319,567 - 65,670,489 (-)NCBI
RefSeq Acc Id: XM_047449763   ⟹   XP_047305719
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,319,567 - 65,670,489 (-)NCBI
RefSeq Acc Id: XM_054349185   ⟹   XP_054205160
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0468,756,500 - 69,108,844 (-)NCBI
RefSeq Acc Id: XM_054349186   ⟹   XP_054205161
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0468,756,500 - 69,108,844 (-)NCBI
RefSeq Acc Id: XM_054349187   ⟹   XP_054205162
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0468,756,500 - 69,108,844 (-)NCBI
RefSeq Acc Id: XM_054349188   ⟹   XP_054205163
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0468,756,500 - 69,108,844 (-)NCBI
RefSeq Acc Id: XM_054349189   ⟹   XP_054205164
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0468,756,500 - 69,108,844 (-)NCBI
RefSeq Acc Id: XM_054349190   ⟹   XP_054205165
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0468,756,500 - 69,108,844 (-)NCBI
RefSeq Acc Id: XM_054349191   ⟹   XP_054205166
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0468,767,490 - 69,108,844 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001268694 (Get FASTA)   NCBI Sequence Viewer  
  NP_001268695 (Get FASTA)   NCBI Sequence Viewer  
  NP_001268696 (Get FASTA)   NCBI Sequence Viewer  
  NP_001305690 (Get FASTA)   NCBI Sequence Viewer  
  NP_004430 (Get FASTA)   NCBI Sequence Viewer  
  NP_872272 (Get FASTA)   NCBI Sequence Viewer  
  XP_005265710 (Get FASTA)   NCBI Sequence Viewer  
  XP_011530037 (Get FASTA)   NCBI Sequence Viewer  
  XP_016863367 (Get FASTA)   NCBI Sequence Viewer  
  XP_016863369 (Get FASTA)   NCBI Sequence Viewer  
  XP_016863370 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305718 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305719 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205160 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205161 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205162 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205163 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205164 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205165 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205166 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA74245 (Get FASTA)   NCBI Sequence Viewer  
  AAI36258 (Get FASTA)   NCBI Sequence Viewer  
  AAI36259 (Get FASTA)   NCBI Sequence Viewer  
  AAI43428 (Get FASTA)   NCBI Sequence Viewer  
  ADO22560 (Get FASTA)   NCBI Sequence Viewer  
  BAD92612 (Get FASTA)   NCBI Sequence Viewer  
  CAD97914 (Get FASTA)   NCBI Sequence Viewer  
  EAX05536 (Get FASTA)   NCBI Sequence Viewer  
  EAX05537 (Get FASTA)   NCBI Sequence Viewer  
  EAX05538 (Get FASTA)   NCBI Sequence Viewer  
  EAX05539 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000273854
  ENSP00000273854.3
  ENSP00000346899
  ENSP00000346899.4
  ENSP00000389208
  ENSP00000389208.2
  ENSP00000427638
  ENSP00000427638.1
  ENSP00000478537
  ENSP00000478537.1
  ENSP00000480763
  ENSP00000480763.1
GenBank Protein P54756 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_872272   ⟸   NM_182472
- Peptide Label: isoform b
- UniProtKB: Q59FT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_004430   ⟸   NM_004439
- Peptide Label: isoform a
- UniProtKB: Q7Z3F2 (UniProtKB/Swiss-Prot),   P54756 (UniProtKB/Swiss-Prot),   Q59FT4 (UniProtKB/TrEMBL),   A0A384MU00 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005265710   ⟸   XM_005265653
- Peptide Label: isoform X4
- UniProtKB: F8W9W0 (UniProtKB/TrEMBL),   Q59FT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001268695   ⟸   NM_001281766
- Peptide Label: isoform d
- UniProtKB: B7ZKW7 (UniProtKB/TrEMBL),   Q59FT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001268694   ⟸   NM_001281765
- Peptide Label: isoform c
- UniProtKB: B7ZKJ3 (UniProtKB/TrEMBL),   Q59FT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001268696   ⟸   NM_001281767
- Peptide Label: isoform e
- UniProtKB: F8VP57 (UniProtKB/TrEMBL),   Q59FT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011530037   ⟸   XM_011531735
- Peptide Label: isoform X1
- UniProtKB: Q59FT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001305690   ⟸   NM_001318761
- Peptide Label: isoform f
- UniProtKB: Q59FT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016863369   ⟸   XM_017007880
- Peptide Label: isoform X6
- UniProtKB: Q59FT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016863367   ⟸   XM_017007878
- Peptide Label: isoform X2
- UniProtKB: Q59FT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016863370   ⟸   XM_017007881
- Peptide Label: isoform X7
- UniProtKB: Q59FT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000480763   ⟸   ENST00000622150
RefSeq Acc Id: ENSP00000478537   ⟸   ENST00000613740
RefSeq Acc Id: ENSP00000273854   ⟸   ENST00000273854
RefSeq Acc Id: ENSP00000389208   ⟸   ENST00000432638
RefSeq Acc Id: ENSP00000427638   ⟸   ENST00000511294
RefSeq Acc Id: ENSP00000346899   ⟸   ENST00000354839
RefSeq Acc Id: XP_047305719   ⟸   XM_047449763
- Peptide Label: isoform X5
RefSeq Acc Id: XP_047305718   ⟸   XM_047449762
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054205164   ⟸   XM_054349189
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054205165   ⟸   XM_054349190
- Peptide Label: isoform X6
RefSeq Acc Id: XP_054205163   ⟸   XM_054349188
- Peptide Label: isoform X4
- UniProtKB: F8W9W0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054205162   ⟸   XM_054349187
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054205161   ⟸   XM_054349186
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054205160   ⟸   XM_054349185
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054205166   ⟸   XM_054349191
- Peptide Label: isoform X7
Protein Domains
Eph LBD   Fibronectin type-III   Protein kinase   SAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P54756-F1-model_v2 AlphaFold P54756 1-1037 view protein structure

Promoters
RGD ID:6867558
Promoter ID:EPDNEW_H6944
Type:initiation region
Name:EPHA5_1
Description:EPH receptor A5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38465,670,463 - 65,670,523EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:3389 AgrOrtholog
COSMIC EPHA5 COSMIC
Ensembl Genes ENSG00000145242 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000273854 ENTREZGENE
  ENST00000273854.7 UniProtKB/Swiss-Prot
  ENST00000354839 ENTREZGENE
  ENST00000354839.8 UniProtKB/Swiss-Prot
  ENST00000432638 ENTREZGENE
  ENST00000432638.6 UniProtKB/TrEMBL
  ENST00000511294 ENTREZGENE
  ENST00000511294.1 UniProtKB/TrEMBL
  ENST00000613740 ENTREZGENE
  ENST00000613740.5 UniProtKB/TrEMBL
  ENST00000622150 ENTREZGENE
  ENST00000622150.4 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ephrin a2 ectodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tumor Necrosis Factor Receptor, subunit A, domain 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000145242 GTEx
HGNC ID HGNC:3389 ENTREZGENE
Human Proteome Map EPHA5 Human Proteome Map
InterPro Eph_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EphA5_rcpt_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ephrin_rcpt_lig-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Growth_fac_rcpt_N_dom UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_ephrin_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_rcpt_V_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:2044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 2044 ENTREZGENE
OMIM 600004 OMIM
PANTHER EPH RECEPTOR A5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPHRIN TYPE-A RECEPTOR 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EphA2_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ephrin_lbd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  fn3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA27821 PharmGKB
PIRSF TyrPK_ephrin_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS FNTYPEIII UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYRKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EGF_2 UniProtKB/Swiss-Prot
  EPH_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RECEPTOR_TYR_KIN_V_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RECEPTOR_TYR_KIN_V_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EPH_lbd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ephrin_rec_like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A384MU00 ENTREZGENE, UniProtKB/TrEMBL
  B7ZKJ3 ENTREZGENE, UniProtKB/TrEMBL
  B7ZKW7 ENTREZGENE, UniProtKB/TrEMBL
  EPHA5_HUMAN UniProtKB/Swiss-Prot
  F8VP57 ENTREZGENE, UniProtKB/TrEMBL
  F8W9W0 ENTREZGENE, UniProtKB/TrEMBL
  P54756 ENTREZGENE
  Q59FT4 ENTREZGENE, UniProtKB/TrEMBL
  Q7Z3F2 ENTREZGENE
UniProt Secondary Q7Z3F2 UniProtKB/Swiss-Prot