(R)-adrenaline multiple interactions ISO RGD:620505 6480464 corticotropin releasing hormone (9-41) inhibits the reaction [CRH protein affects the abundance of Epinephrine] CTD PMID:1320258 (R)-adrenaline increases abundance ISO RGD:620505 6480464 CRH results in increased abundance of Epinephrine CTD PMID:1320258 (R)-noradrenaline multiple interactions ISO RGD:620505 6480464 corticotropin releasing hormone (9-41) inhibits the reaction [CRH protein affects the abundance of Norepinephrine] more ... CTD PMID:1320258 , PMID:3497798 (R)-noradrenaline increases abundance ISO RGD:620505 6480464 CRH results in increased abundance of Norepinephrine CTD PMID:1320258 (S)-colchicine decreases expression ISO RGD:620505 6480464 Colchicine results in decreased expression of CRH protein CTD PMID:2453250 (S)-colchicine increases expression ISO RGD:620505 6480464 Colchicine results in increased expression of CRH mRNA CTD PMID:1850078 (S)-nicotine decreases expression ISO RGD:620505 6480464 Nicotine results in decreased expression of CRH mRNA, Nicotine results in decreased expression of CRH protein CTD PMID:22265867 , PMID:28555334 (S)-nicotine increases expression ISO RGD:620505 6480464 Nicotine results in increased expression of CRH protein CTD PMID:23623838 (S)-nicotine decreases expression ISO RGD:730947 6480464 Nicotine results in decreased expression of CRH mRNA CTD PMID:21955143 17beta-estradiol multiple interactions ISO RGD:620505 6480464 Estradiol inhibits the reaction [Ethanol results in increased expression of CRH mRNA] CTD PMID:22384198 17beta-estradiol 3-benzoate increases expression ISO RGD:620505 6480464 estradiol 3-benzoate results in increased expression of CRH mRNA CTD PMID:32741896 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2 more ... CTD PMID:28189027 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:28189027 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:620505 6480464 Tetrachlorodibenzodioxin results in increased expression of CRH mRNA CTD PMID:18824019 2,4,6-trinitrobenzenesulfonic acid decreases expression ISO RGD:620505 6480464 Trinitrobenzenesulfonic Acid results in decreased expression of CRH mRNA CTD PMID:11959675 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:620505 6480464 Trinitrobenzenesulfonic Acid results in increased expression of CRH mRNA CTD PMID:11668029 2-arachidonoylglycerol increases abundance ISO RGD:730947 6480464 CRH protein results in increased abundance of glyceryl 2-arachidonate CTD PMID:26821211 3',5'-cyclic AMP multiple interactions EXP 6480464 [CRHR1 protein binds to and results in increased activity of CRH protein] which results in increased abundance of Cyclic AMP, Progesterone promotes the reaction [[CRHR1 protein binds to and results in increased activity of CRH protein] which results in increased abundance of Cyclic AMP] CTD PMID:20702571 3',5'-cyclic AMP multiple interactions ISO RGD:620505 6480464 CRH protein inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP] more ... CTD PMID:2153673 3,5,6-trichloro-2-pyridinol multiple interactions ISO RGD:730947 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 3,5,6-trichloropyridine-2-one multiple interactions ISO RGD:730947 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide decreases expression EXP 6480464 Raclopride results in decreased expression of CRH mRNA CTD PMID:16205782 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions EXP 6480464 bisindolylmaleimide I inhibits the reaction [Aflatoxin B1 results in increased expression of CRH mRNA] CTD PMID:26026912 3-phenoxybenzoic acid multiple interactions ISO RGD:730947 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 3alpha-hydroxy-5beta-pregnan-20-one affects expression ISO RGD:620505 6480464 Pregnanolone affects the expression of CRH mRNA CTD PMID:7816204 3alpha-hydroxy-5beta-pregnan-20-one multiple interactions ISO RGD:620505 6480464 Pregnanolone inhibits the reaction [Methoxamine results in increased secretion of CRH protein] CTD PMID:7816204 4,4'-diaminodiphenylmethane increases expression ISO RGD:620505 6480464 4, 4'-diaminodiphenylmethane results in increased expression of CRH mRNA CTD PMID:30723492 8-Br-cAMP multiple interactions ISO RGD:620505 6480464 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone]] CTD PMID:2153673 8-OH-DPAT multiple interactions ISO RGD:620505 6480464 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [CRH protein results in increased secretion of Serotonin] CTD PMID:14575894 acephate increases expression ISO RGD:620505 6480464 acephate results in increased expression of CRH mRNA CTD PMID:12039681 acephate increases secretion ISO RGD:620505 6480464 acephate results in increased secretion of CRH protein CTD PMID:12039681 acephate multiple interactions ISO RGD:620505 6480464 acephate promotes the reaction [FOS protein binds to CRH promoter] more ... CTD PMID:12039681 acetylcholine increases expression ISO RGD:620505 6480464 Acetylcholine results in increased expression of CRH mRNA CTD PMID:7588217 adinazolam multiple interactions ISO RGD:620505 6480464 adinazolam inhibits the reaction [CRF protein results in increased secretion of beta-Endorphin] CTD PMID:1480515 aflatoxin B1 increases expression ISO RGD:730947 6480464 Aflatoxin B1 results in increased expression of CRH mRNA, Aflatoxin B1 results in increased expression of CRH protein CTD PMID:26968497 aflatoxin B1 decreases methylation EXP 6480464 Aflatoxin B1 results in decreased methylation of CRH gene CTD PMID:27153756 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of CRH mRNA, Aflatoxin B1 results in increased expression of CRH protein CTD PMID:26026912 aflatoxin B1 multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Aflatoxin B1 results in increased expression of CRH mRNA], bisindolylmaleimide I inhibits the reaction [Aflatoxin B1 results in increased expression of CRH mRNA] CTD PMID:26026912 alpha-Zearalanol multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Zeranol results in increased expression of CRH mRNA] CTD PMID:23538034 alpha-Zearalanol increases expression EXP 6480464 Zeranol results in increased expression of CRH mRNA, Zeranol results in increased expression of CRH protein CTD PMID:23538034 AM-251 multiple interactions ISO RGD:620505 6480464 [AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CRH mRNA CTD PMID:26468265 AM-251 increases expression ISO RGD:620505 6480464 AM 251 results in increased expression of CRH mRNA CTD PMID:26468265 ammonium chloride affects expression ISO RGD:620505 6480464 Ammonium Chloride affects the expression of CRH mRNA CTD PMID:16483693 amphetamine affects expression ISO RGD:620505 6480464 Amphetamine affects the expression of CRH protein CTD PMID:15238432 anandamide decreases abundance ISO RGD:730947 6480464 CRH protein results in decreased abundance of anandamide CTD PMID:26821211 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [2 more ... CTD PMID:28189027 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of CRH mRNA CTD PMID:15761015 astemizole multiple interactions ISO RGD:620505 6480464 Astemizole inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]] CTD PMID:18835572 astressin multiple interactions ISO RGD:620505 6480464 [IL1RN protein co-treated with astressin] promotes the reaction [AGT protein results in increased expression of CRH protein], astressin promotes the reaction [AGT protein results in increased expression of CRH protein] CTD PMID:33872574 atropine multiple interactions EXP 6480464 [Atropine co-treated with SR 140333 co-treated with SR 48968] results in decreased activity of CRH protein CTD PMID:12906840 atropine multiple interactions ISO RGD:620505 6480464 Atropine inhibits the reaction [acephate results in increased expression of CRH mRNA] more ... CTD PMID:12039681 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of CRH mRNA CTD PMID:22316170 benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of CRH promoter CTD PMID:27901495 beta-endorphin increases secretion ISO RGD:620505 6480464 CRF protein results in increased secretion of beta-Endorphin CTD PMID:1480515 beta-endorphin decreases secretion ISO RGD:620505 6480464 beta-Endorphin results in decreased secretion of CRH protein CTD PMID:3031743 beta-endorphin multiple interactions ISO RGD:620505 6480464 adinazolam inhibits the reaction [CRF protein results in increased secretion of beta-Endorphin] more ... CTD PMID:1480515 , PMID:3031743 beta-naphthoflavone decreases expression EXP 6480464 beta-Naphthoflavone results in decreased expression of CRH mRNA CTD PMID:32858204 betaxolol multiple interactions ISO RGD:620505 6480464 Betaxolol affects the reaction [Cocaine affects the expression of CRH mRNA] CTD PMID:18596687 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of CRH mRNA CTD PMID:31163220 bisphenol A increases expression ISO RGD:730947 6480464 bisphenol A results in increased expression of CRH mRNA, bisphenol A results in increased expression of CRH protein CTD PMID:23545179 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of CRH gene CTD PMID:31601247 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of CRH gene CTD PMID:31601247 bisphenol A multiple interactions ISO RGD:730947 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 bisphenol A decreases expression ISO RGD:620505 6480464 bisphenol A results in decreased expression of CRH mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:620505 6480464 bisphenol A results in increased expression of CRH mRNA CTD PMID:24857958 , PMID:26060449 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CRH mRNA CTD PMID:22564983 , PMID:25784278 Butylbenzyl phthalate multiple interactions ISO RGD:730947 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 Butylparaben multiple interactions ISO RGD:620505 6480464 [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of CRH mRNA CTD PMID:34383603 cannabidiol multiple interactions ISO RGD:730947 6480464 [Cannabidiol co-treated with Sertraline] results in decreased expression of CRH mRNA CTD PMID:34262461 carbon dioxide increases response to substance EXP 6480464 CRH protein results in increased susceptibility to Carbon Dioxide CTD PMID:8957205 chlorpromazine decreases expression EXP 6480464 Chlorpromazine results in decreased expression of CRH mRNA CTD PMID:16205782 chlorpyrifos increases expression ISO RGD:620505 6480464 Chlorpyrifos results in increased expression of CRH mRNA CTD PMID:20682304 cis-caffeic acid multiple interactions ISO RGD:620505 6480464 caffeic acid inhibits the reaction [Malathion results in decreased expression of CRH mRNA] CTD PMID:25404496 clozapine decreases expression EXP 6480464 Clozapine results in decreased expression of CRH mRNA CTD PMID:16205782 cobalt dichloride increases secretion EXP 6480464 cobaltous chloride results in increased secretion of CRH protein CTD PMID:11232018 cocaine multiple interactions ISO RGD:620505 6480464 Betaxolol affects the reaction [Cocaine affects the expression of CRH mRNA] more ... CTD PMID:11597771 more ... cocaine affects expression ISO RGD:620505 6480464 Cocaine affects the expression of CRH mRNA, Cocaine affects the expression of CRH protein CTD PMID:11597771 more ... colforsin daropate hydrochloride multiple interactions ISO RGD:620505 6480464 CRH protein inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP] more ... CTD PMID:2153673 colforsin daropate hydrochloride increases secretion EXP 6480464 Colforsin results in increased secretion of CRH protein CTD PMID:33144174 colforsin daropate hydrochloride multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Colforsin] results in increased expression of CRH mRNA CTD PMID:33144174 copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of CRH mRNA CTD PMID:19549813 corticosterone multiple interactions ISO RGD:620505 6480464 Astemizole inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]] more ... CTD PMID:18835572 more ... corticosterone decreases expression ISO RGD:620505 6480464 Corticosterone results in decreased expression of CRH mRNA CTD PMID:32437893 corticosterone multiple interactions ISO RGD:730947 6480464 CRH protein affects the reaction [[DUSP8 protein affects the susceptibility to Dietary Fats] which affects the abundance of Corticosterone] CTD PMID:32780722 corticosterone increases expression ISO RGD:620505 6480464 Corticosterone results in increased expression of CRH mRNA, Corticosterone results in increased expression of CRH protein CTD PMID:26821211 , PMID:32733244 corticosterone affects expression ISO RGD:620505 6480464 Corticosterone affects the expression of CRH mRNA CTD PMID:7816204 corticosterone increases abundance ISO RGD:730947 6480464 CRH protein results in increased abundance of Corticosterone CTD PMID:21359208 corticotropin multiple interactions ISO RGD:620505 6480464 Astemizole inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]] more ... CTD PMID:18835572 corticotropin increases secretion ISO RGD:620505 6480464 CRH protein results in increased secretion of Adrenocorticotropic Hormone CTD PMID:18835572 cortisol increases abundance EXP 6480464 CRH protein results in increased abundance of Hydrocortisone CTD PMID:20570051 , PMID:8888355 Cuprizon decreases expression ISO RGD:620505 6480464 Cuprizone results in decreased expression of CRH mRNA CTD PMID:26577399 , PMID:27523638 cyanamide multiple interactions ISO RGD:620505 6480464 [Cyanamide co-treated with Ethanol] results in increased expression of CRH mRNA, [Ethanol co-treated with Cyanamide] results in increased expression of CRH mRNA CTD PMID:11139417 , PMID:16375214 cyanamide increases expression ISO RGD:620505 6480464 Cyanamide results in increased expression of CRH mRNA CTD PMID:10718921 more ... cyclophosphamide increases expression ISO RGD:620505 6480464 Cyclophosphamide results in increased expression of CRH mRNA, Cyclophosphamide results in increased expression of CRH protein CTD PMID:15276878 , PMID:16614059 cyclophosphamide increases expression ISO RGD:730947 6480464 Cyclophosphamide results in increased expression of CRH mRNA CTD PMID:17335920 DDE multiple interactions ISO RGD:730947 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 DDE multiple interactions ISO RGD:620505 6480464 [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of CRH mRNA CTD PMID:34383603 dexamethasone increases expression ISO RGD:620505 6480464 Dexamethasone results in increased expression of CRH mRNA CTD PMID:18819432 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of CRH mRNA CTD PMID:15761015 diazinon increases expression ISO RGD:620505 6480464 Diazinon results in increased expression of CRH mRNA CTD PMID:20682304 dibutyl phthalate multiple interactions ISO RGD:730947 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 dieldrin increases expression ISO RGD:620505 6480464 Dieldrin results in increased expression of CRH mRNA CTD PMID:20682304 diethyl phthalate multiple interactions ISO RGD:730947 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 Diisodecyl phthalate multiple interactions ISO RGD:730947 6480464 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3 more ... CTD PMID:32518293 diprotium oxide multiple interactions ISO RGD:620505 6480464 [AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CRH mRNA CTD PMID:26468265 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRH mRNA CTD PMID:27188386 doxapram increases expression ISO RGD:620505 6480464 Doxapram results in increased expression of CRH mRNA, Doxapram results in increased expression of CRH protein CTD PMID:16269353 dynorphin A decreases secretion ISO RGD:620505 6480464 Dynorphins results in decreased secretion of CRH protein CTD PMID:3031743 dynorphin A multiple interactions ISO RGD:620505 6480464 Dynorphins inhibits the reaction [Nitroprusside results in increased secretion of CRH protein], Naltrexone affects the reaction [Dynorphins results in decreased secretion of CRH protein] CTD PMID:3031743 E-4031 multiple interactions ISO RGD:620505 6480464 E 4031 inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]] CTD PMID:18835572 enzacamene multiple interactions ISO RGD:620505 6480464 [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of CRH mRNA CTD PMID:34383603 ethanol affects expression ISO RGD:620505 6480464 Ethanol affects the expression of CRH mRNA CTD PMID:18819432 ethanol decreases expression ISO RGD:620505 6480464 Ethanol results in decreased expression of CRH mRNA CTD PMID:22039522 ethanol increases expression ISO RGD:620505 6480464 Ethanol results in increased expression of CRH mRNA CTD PMID:16925589 more ... ethanol increases expression ISO RGD:730947 6480464 Ethanol results in increased expression of CRH mRNA CTD PMID:21955143 ethanol multiple interactions ISO RGD:620505 6480464 [Cholesterol more ... CTD PMID:11139417 more ... fentanyl affects expression ISO RGD:620505 6480464 Fentanyl affects the expression of CRH mRNA CTD PMID:18819432 finasteride multiple interactions EXP 6480464 [Finasteride results in increased susceptibility to IL1B protein] which results in increased expression of CRH mRNA CTD PMID:19458216 flavonoids decreases expression ISO RGD:620505 6480464 Flavonoids results in decreased expression of CRH mRNA CTD PMID:18035473 fluoxetine decreases expression ISO RGD:730947 6480464 Fluoxetine results in decreased expression of CRH mRNA CTD PMID:20374287 fluoxetine increases expression ISO RGD:620505 6480464 Fluoxetine results in increased expression of CRH mRNA CTD PMID:9740405 fluoxetine decreases expression ISO RGD:620505 6480464 Fluoxetine results in decreased expression of CRH mRNA CTD PMID:1351783 formaldehyde increases expression ISO RGD:730947 6480464 Formaldehyde results in increased expression of CRH protein CTD PMID:15196973 , PMID:15805735 fulvestrant multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of CRH gene CTD PMID:31601247 gamma-aminobutyric acid multiple interactions ISO RGD:620505 6480464 gamma-Aminobutyric Acid inhibits the reaction [acephate results in increased expression of CRH mRNA] more ... CTD PMID:12039681 genistein multiple interactions ISO RGD:730947 6480464 [lipopolysaccharide more ... CTD PMID:21816468 glycidol decreases expression ISO RGD:620505 6480464 glycidol results in decreased expression of CRH mRNA CTD PMID:24915197 Goe 6976 multiple interactions EXP 6480464 CRH protein inhibits the reaction [Go 6976 results in increased abundance of Progesterone] more ... CTD PMID:17170093 GTP decreases activity ISO RGD:620505 6480464 Guanosine Triphosphate results in decreased activity of CRH protein CTD PMID:2153673 guanosine 5'-[beta,gamma-imido]triphosphate multiple interactions ISO RGD:620505 6480464 CRH protein inhibits the reaction [[LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP] CTD PMID:2153673 guanosine 5'-[beta,gamma-imido]triphosphate decreases activity ISO RGD:620505 6480464 Guanylyl Imidodiphosphate results in decreased activity of CRH protein CTD PMID:2153673 haloperidol decreases expression EXP 6480464 Haloperidol results in decreased expression of CRH mRNA CTD PMID:16205782 hemin increases secretion EXP 6480464 Hemin results in increased secretion of CRH protein CTD PMID:11232018 hemin multiple interactions EXP 6480464 mesoporphyrin IX analog inhibits the reaction [Hemin results in increased secretion of CRH protein] CTD PMID:11232018 hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of CRH mRNA CTD PMID:26339600 idazoxan decreases expression ISO RGD:620505 6480464 Idazoxan results in decreased expression of CRH mRNA CTD PMID:1351783 imipramine affects activity ISO RGD:620505 6480464 Imipramine affects the activity of CRH protein CTD PMID:2553044 indometacin multiple interactions ISO RGD:620505 6480464 Indomethacin inhibits the reaction [IL1B protein results in increased secretion of CRH protein] more ... CTD PMID:11852909 ketamine decreases expression ISO RGD:620505 6480464 Ketamine results in decreased expression of CRH mRNA CTD PMID:20080153 lidocaine increases expression ISO RGD:620505 6480464 Lidocaine results in increased expression of CRH mRNA CTD PMID:35283115 linsidomine increases expression ISO RGD:620505 6480464 linsidomine results in increased expression of CRH mRNA CTD PMID:10460269 linsidomine multiple interactions ISO RGD:620505 6480464 CRH protein affects the reaction [linsidomine results in increased secretion of POMC protein alternative form] CTD PMID:10460269 linuron multiple interactions ISO RGD:620505 6480464 [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of CRH mRNA CTD PMID:34383603 lipopolysaccharide multiple interactions ISO RGD:620505 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased expression of CRH mRNA] more ... CTD PMID:11852909 , PMID:21959975 lipopolysaccharide increases secretion ISO RGD:620505 6480464 Lipopolysaccharides results in increased secretion of CRH protein CTD PMID:11852909 lipopolysaccharide increases expression ISO RGD:620505 6480464 Lipopolysaccharides results in increased expression of CRH mRNA, Lipopolysaccharides results in increased expression of CRH protein CTD PMID:21959975 lipopolysaccharide affects expression ISO RGD:730947 6480464 Lipopolysaccharides affects the expression of CRH mRNA CTD PMID:15667454 malathion multiple interactions ISO RGD:620505 6480464 caffeic acid inhibits the reaction [Malathion results in decreased expression of CRH mRNA] CTD PMID:25404496 malathion decreases expression ISO RGD:620505 6480464 Malathion results in decreased expression of CRH mRNA CTD PMID:20233601 , PMID:25404496 manganese atom multiple interactions ISO RGD:620505 6480464 CRH protein inhibits the reaction [Manganese results in increased chemical synthesis of Cyclic AMP] CTD PMID:2153673 manganese(0) multiple interactions ISO RGD:620505 6480464 CRH protein inhibits the reaction [Manganese results in increased chemical synthesis of Cyclic AMP] CTD PMID:2153673 mesoporphyrin IX multiple interactions EXP 6480464 mesoporphyrin IX analog inhibits the reaction [Hemin results in increased secretion of CRH protein] CTD PMID:11232018 metamizole sodium multiple interactions ISO RGD:620505 6480464 Dipyrone inhibits the reaction [IL1B protein results in increased secretion of CRH protein] more ... CTD PMID:11852909 methamidophos multiple interactions ISO RGD:620505 6480464 Atropine inhibits the reaction [methamidophos results in increased expression of CRH mRNA] more ... CTD PMID:12039681 methamidophos increases secretion ISO RGD:620505 6480464 methamidophos results in increased secretion of CRH protein CTD PMID:12039681 methamidophos increases expression ISO RGD:620505 6480464 methamidophos results in increased expression of CRH mRNA CTD PMID:12039681 methamphetamine multiple interactions ISO RGD:620505 6480464 [Methamphetamine co-treated with SCH 23390] results in increased expression of CRH mRNA CTD PMID:19564919 methamphetamine increases expression ISO RGD:620505 6480464 Methamphetamine results in increased expression of CRH mRNA CTD PMID:19564919 methoxamine multiple interactions ISO RGD:620505 6480464 Pregnanolone inhibits the reaction [Methoxamine results in increased secretion of CRH protein] CTD PMID:7816204 methoxamine increases secretion ISO RGD:620505 6480464 Methoxamine results in increased secretion of CRH protein CTD PMID:7816204 methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of CRH mRNA CTD PMID:34089799 mifepristone multiple interactions ISO RGD:620505 6480464 Mifepristone inhibits the reaction [Ethanol results in increased expression of CRH mRNA] CTD PMID:22039522 monosodium L-glutamate decreases expression ISO RGD:620505 6480464 Sodium Glutamate results in decreased expression of CRH mRNA CTD PMID:8071649 morphine increases expression ISO RGD:730947 6480464 Morphine deficiency results in increased expression of CRH mRNA, Morphine results in increased expression of CRH mRNA CTD PMID:21955143 , PMID:27126842 naloxone decreases expression ISO RGD:620505 6480464 Naloxone results in decreased expression of CRH mRNA CTD PMID:12431775 naloxone multiple interactions ISO RGD:620505 6480464 Naloxone promotes the reaction [AGT protein results in increased expression of CRH protein] CTD PMID:33872574 naltrexone multiple interactions ISO RGD:620505 6480464 Naltrexone affects the reaction [Dynorphins results in decreased secretion of CRH protein], Naltrexone inhibits the reaction [beta-Endorphin results in decreased secretion of CRH protein] CTD PMID:3031743 naltrexone increases secretion ISO RGD:620505 6480464 Naltrexone results in increased secretion of CRH protein CTD PMID:3031743 nickel atom decreases expression ISO RGD:620505 6480464 Nickel results in decreased expression of CRH mRNA CTD PMID:20682304 nicotine decreases expression ISO RGD:620505 6480464 Nicotine results in decreased expression of CRH mRNA, Nicotine results in decreased expression of CRH protein CTD PMID:22265867 , PMID:28555334 nicotine increases expression ISO RGD:620505 6480464 Nicotine results in increased expression of CRH protein CTD PMID:23623838 nicotine decreases expression ISO RGD:730947 6480464 Nicotine results in decreased expression of CRH mRNA CTD PMID:21955143 nitric oxide multiple interactions ISO RGD:620505 6480464 CRH protein affects the reaction [Nitric Oxide results in increased secretion of POMC protein alternative form] CTD PMID:10460269 nitric oxide increases expression ISO RGD:620505 6480464 Nitric Oxide results in increased expression of CRH mRNA CTD PMID:10460269 nitroprusside multiple interactions ISO RGD:620505 6480464 beta-Endorphin inhibits the reaction [Nitroprusside results in increased secretion of CRH protein] more ... CTD PMID:3015567 more ... nitroprusside increases secretion ISO RGD:620505 6480464 Nitroprusside results in increased secretion of CRH protein CTD PMID:3015567 , PMID:3031743 paracetamol multiple interactions ISO RGD:620505 6480464 [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of CRH mRNA CTD PMID:34383603 paraquat increases expression ISO RGD:730947 6480464 Paraquat results in increased expression of CRH mRNA, Paraquat results in increased expression of CRH protein CTD PMID:30744883 pentobarbital affects expression ISO RGD:620505 6480464 Pentobarbital affects the expression of CRH mRNA CTD PMID:18819432 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:620505 6480464 perfluorooctane sulfonic acid results in decreased expression of CRH mRNA CTD PMID:24440345 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Colforsin] results in increased expression of CRH mRNA CTD PMID:33144174 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:620505 6480464 perfluorooctane sulfonic acid results in decreased expression of and results in decreased secretion of CRH protein CTD PMID:24440345 permethrin increases expression ISO RGD:620505 6480464 Permethrin results in increased expression of CRH mRNA CTD PMID:19017407 Phenelzine decreases expression ISO RGD:620505 6480464 Phenelzine results in decreased expression of CRH mRNA CTD PMID:1351783 phenytoin affects expression ISO RGD:620505 6480464 Phenytoin affects the expression of CRH mRNA CTD PMID:20345932 pioglitazone increases expression EXP 6480464 Pioglitazone results in increased expression of CRH mRNA CTD PMID:30031879 prednisolone decreases expression ISO RGD:620505 6480464 Prednisolone results in decreased expression of CRH protein CTD PMID:9625448 prednisolone multiple interactions ISO RGD:620505 6480464 sairei-to inhibits the reaction [Prednisolone results in decreased expression of CRH protein] CTD PMID:9625448 progesterone multiple interactions EXP 6480464 CRH protein inhibits the reaction [Go 6976 results in increased abundance of Progesterone] more ... CTD PMID:17170093 , PMID:20702571 progesterone increases secretion ISO RGD:620505 6480464 CRH protein results in increased secretion of Progesterone CTD PMID:23133512 progesterone decreases abundance EXP 6480464 CRH protein results in decreased abundance of Progesterone CTD PMID:17170093 promazine decreases expression EXP 6480464 Promazine results in decreased expression of CRH mRNA CTD PMID:16205782 propranolol multiple interactions ISO RGD:620505 6480464 Propranolol affects the reaction [Norepinephrine affects the expression of and affects the secretion of CRH protein] more ... CTD PMID:12039681 , PMID:3497798 quercetin affects expression ISO RGD:620505 6480464 Quercetin affects the expression of CRH mRNA CTD PMID:19423323 reserpine increases expression ISO RGD:620505 6480464 Reserpine results in increased expression of CRH mRNA, Reserpine results in increased expression of CRH protein CTD PMID:1850078 rimonabant decreases expression ISO RGD:620505 6480464 Rimonabant results in decreased expression of CRH mRNA CTD PMID:15099659 rimonabant multiple interactions ISO RGD:620505 6480464 Dronabinol affects the reaction [Rimonabant results in decreased expression of CRH mRNA], Rimonabant inhibits the reaction [HU 211 results in decreased expression of CRH mRNA] CTD PMID:12968131 , PMID:15099659 risperidone decreases expression EXP 6480464 Risperidone results in decreased expression of CRH mRNA CTD PMID:16205782 SB 203580 multiple interactions ISO RGD:620505 6480464 SB 203580 inhibits the reaction [Lipopolysaccharides results in increased expression of CRH mRNA] CTD PMID:21959975 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [2 more ... CTD PMID:28189027 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRH mRNA CTD PMID:27188386 SCH 23390 multiple interactions ISO RGD:620505 6480464 [Methamphetamine co-treated with SCH 23390] results in increased expression of CRH mRNA, SCH 23390 affects the reaction [Cocaine affects the expression of CRH mRNA] CTD PMID:11597771 , PMID:19564919 SCH 23390 increases expression ISO RGD:620505 6480464 SCH 23390 results in increased expression of CRH mRNA CTD PMID:19564919 serotonin multiple interactions ISO RGD:620505 6480464 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [CRH protein results in increased secretion of Serotonin], corticotropin releasing hormone (9-41) inhibits the reaction [CRH protein results in increased secretion of Serotonin] CTD PMID:14575894 serotonin increases secretion ISO RGD:620505 6480464 CRH protein results in increased secretion of Serotonin CTD PMID:14575894 sertraline multiple interactions ISO RGD:730947 6480464 [Cannabidiol co-treated with Sertraline] results in decreased expression of CRH mRNA CTD PMID:34262461 silicon dioxide increases expression EXP 6480464 Silicon Dioxide analog results in increased expression of CRH mRNA CTD PMID:25895662 sodium arsenate increases expression ISO RGD:730947 6480464 sodium arsenate results in increased expression of CRH protein CTD PMID:22960421 Soman increases expression ISO RGD:620505 6480464 Soman results in increased expression of CRH mRNA CTD PMID:19281266 sphingosine multiple interactions ISO RGD:620505 6480464 Sphingosine inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]] CTD PMID:2153673 staurosporine multiple interactions ISO RGD:620505 6480464 Staurosporine inhibits the reaction [CRH protein inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]] CTD PMID:2153673 Sulpyrine multiple interactions ISO RGD:620505 6480464 Dipyrone inhibits the reaction [IL1B protein results in increased secretion of CRH protein] more ... CTD PMID:11852909 telmisartan multiple interactions ISO RGD:620505 6480464 Telmisartan inhibits the reaction [AGT protein results in increased expression of CRH protein] CTD PMID:33872574 terbutaline decreases expression EXP 6480464 Terbutaline results in decreased expression of CRH mRNA CTD PMID:17127497 testosterone multiple interactions ISO RGD:620505 6480464 2-methyl-4-(N-propyl-N-cycloproanemethylamino)-5-chloro-6-(2 more ... CTD PMID:18719027 more ... testosterone increases secretion ISO RGD:620505 6480464 CRH protein results in increased secretion of Testosterone CTD PMID:23133512 tetraethylammonium multiple interactions ISO RGD:620505 6480464 Tetraethylammonium promotes the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone] CTD PMID:18835572 tetrodotoxin decreases activity EXP 6480464 Tetrodotoxin results in decreased activity of CRH protein CTD PMID:12906840 thioridazine decreases expression EXP 6480464 Thioridazine results in decreased expression of CRH mRNA CTD PMID:16205782 toluene increases expression ISO RGD:620505 6480464 Toluene results in increased expression of CRH protein CTD PMID:15707876 trans-caffeic acid multiple interactions ISO RGD:620505 6480464 caffeic acid inhibits the reaction [Malathion results in decreased expression of CRH mRNA] CTD PMID:25404496 trichloroethene decreases expression ISO RGD:620505 6480464 Trichloroethylene results in decreased expression of CRH mRNA CTD PMID:33387578 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions EXP 6480464 [Atropine co-treated with SR 140333 co-treated with SR 48968] results in decreased activity of CRH protein CTD PMID:12906840 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions ISO RGD:620505 6480464 Atropine inhibits the reaction [acephate results in increased expression of CRH mRNA] more ... CTD PMID:12039681 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of CRH mRNA CTD PMID:24383497 valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRH mRNA CTD PMID:27188386 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of CRH mRNA CTD PMID:25979313 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of CRH mRNA CTD PMID:23179753 vanadyl sulfate decreases expression EXP 6480464 vanadyl sulfate results in decreased expression of CRH mRNA CTD PMID:16330358 water multiple interactions ISO RGD:620505 6480464 [AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CRH mRNA CTD PMID:26468265 yohimbine multiple interactions ISO RGD:620505 6480464 Yohimbine affects the reaction [Norepinephrine affects the expression of and affects the secretion of CRH protein], Yohimbine inhibits the reaction [Nitroprusside results in increased expression of and results in increased secretion of CRH protein] CTD PMID:3497798
