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Gene: ATP2A1 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1) Homo sapiens
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Symbol: ATP2A1
Name: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
Description: Exhibits calcium ion binding activity; calcium transmembrane transporter activity, phosphorylative mechanism; and protein homodimerization activity. Involved in several processes, including cellular calcium ion homeostasis; maintenance of mitochondrion location; and regulation of striated muscle contraction. Localizes to the H zone; I band; and endoplasmic reticulum membrane. Implicated in Brody myopathy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP2A; ATPase, Ca++ transporting, cardiac muscle, fast twitch 1; calcium pump 1; calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform; endoplasmic reticulum class 1/2 Ca(2+) ATPase; sarcoplasmic/endoplasmic reticulum calcium ATPase 1; SERCA1; SR Ca(2+)-ATPase 1
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1628,878,405 - 28,904,509 (+)Ensembl
GRCh381628,878,488 - 28,904,511 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371628,889,192 - 28,915,830 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361628,797,310 - 28,823,331 (+)NCBINCBI36hg18NCBI36
Build 341628,797,309 - 28,823,331NCBI
Celera1627,844,578 - 27,896,644 (+)NCBI
Cytogenetic Map16p11.2NCBI
HuRef1626,757,144 - 26,783,172 (+)NCBIHuRef
CHM1_11629,901,645 - 29,927,644 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on ATP2A1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731640
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.