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Gene: PLD1 (phospholipase D1) Homo sapiens
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Symbol: PLD1
Name: phospholipase D1
Description: Predicted to have N-acylphosphatidylethanolamine-specific phospholipase D activity; phosphatidylinositol binding activity; and phospholipase D activity. Involved in regulation of microvillus assembly and regulation of synaptic vesicle cycle. Localizes to several cellular components, including the apical plasma membrane; cholinergic synapse; and cytoplasmic vesicle. Biomarker of pancreatic ductal adenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: choline phosphatase 1; CVDD; hPLD1; phosphatidylcholine-hydrolyzing phospholipase D1; phospholipase D1, phosphatidylcholine-specific; PLD 1
Orthologs:
Mus musculus (house mouse) : Pld1 (phospholipase D1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pld1 (phospholipase D1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pld1 (phospholipase D1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLD1 (phospholipase D1)
Canis lupus familiaris (dog) : PLD1 (phospholipase D1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pld1 (phospholipase D1)
Sus scrofa (pig) : PLD1 (phospholipase D1)
Chlorocebus sabaeus (African green monkey) : PLD1 (phospholipase D1)
Heterocephalus glaber (naked mole-rat) : Pld1 (phospholipase D1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl3171,600,404 - 171,810,950 (-)Ensembl
GRCh383171,600,404 - 171,810,483 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373171,318,195 - 171,528,284 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363172,801,339 - 172,938,566 (-)NCBINCBI36hg18NCBI36
Build 343172,801,346 - 172,938,574NCBI
Celera3169,718,435 - 169,928,143 (-)NCBI
Cytogenetic Map3q26.31NCBI
HuRef3168,688,221 - 168,898,341 (-)NCBIHuRef
CHM1_13171,281,084 - 171,491,135 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PLD1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70829
Created: 2002-06-25
Species: Homo sapiens
Last Modified: 2020-01-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.