(+)-artemisinin multiple interactions EXP 6480464 artemisinin inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:27504015 (+)-pilocarpine multiple interactions EXP 6480464 Pilocarpine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 (-)-noscapine multiple interactions EXP 6480464 Noscapine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 (-)-selegiline multiple interactions EXP 6480464 Selegiline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 (E)-thiamethoxam decreases activity EXP 6480464 Thiamethoxam results in decreased activity of SLC22A2 protein CTD PMID:31364238 (S)-atropine multiple interactions EXP 6480464 Hyoscyamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 (S)-fenfluramine multiple interactions EXP 6480464 Dexfenfluramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 (S)-nicotine affects response to substance EXP 6480464 SLC22A2 gene SNP affects the susceptibility to Nicotine CTD PMID:25143296 (S)-nicotine multiple interactions EXP 6480464 Nicotine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 1,1'-diethyl-2,2'-cyanine multiple interactions EXP 6480464 pseudoisocyanine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:12110607 1,1-dichloroethene decreases expression ISO RGD:62229 6480464 vinylidene chloride results in decreased expression of SLC22A2 mRNA CTD PMID:26682919 1,3-diphenylguanidine multiple interactions EXP 6480464 diphenylguanidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane multiple interactions EXP 6480464 homochlorocyclizine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 1-\{2-[(4-chlorobenzyl)sulfanyl]-2-(2,4-dichlorophenyl)ethyl\}-1H-imidazole multiple interactions EXP 6480464 sulconazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases response to substance ISO RGD:62229 6480464 SLC22A2 protein results in increased susceptibility to 1-Methyl-4-phenyl-1 more ... CTD PMID:25248837 1-methylnicotinamide increases import EXP 6480464 SLC22A2 results in increased import of N(1)-methylnicotinamide CTD PMID:9260930 1-naphthyl isothiocyanate increases expression ISO RGD:62229 6480464 1-Naphthylisothiocyanate results in increased expression of SLC22A2 mRNA CTD PMID:15913567 1-naphthyl isothiocyanate multiple interactions ISO RGD:62229 6480464 O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1, 2-diolate inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SLC22A2 mRNA] CTD PMID:15913567 11-deoxycorticosterone multiple interactions ISO RGD:61936 6480464 Desoxycorticosterone inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:9830022 17alpha-ethynylestradiol decreases expression ISO RGD:61936 6480464 Ethinyl Estradiol results in decreased expression of SLC22A2 mRNA, Ethinyl Estradiol results in decreased expression of SLC22A2 protein CTD PMID:19002567 17alpha-hydroxyprogesterone multiple interactions EXP 6480464 17-alpha-Hydroxyprogesterone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 17beta-estradiol multiple interactions ISO RGD:61936 6480464 Estradiol affects the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:9830022 2-(1-naphthalenylmethyl)-4,5-dihydro-1H-imidazole multiple interactions EXP 6480464 Naphazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions EXP 6480464 Verapamil inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions ISO RGD:61936 6480464 Verapamil inhibits the reaction [SLC22A2 protein results in increased uptake of mepiquat] CTD PMID:33639197 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one multiple interactions EXP 6480464 Praziquantel inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 2-Amino-3-methyl-9H-pyrido[2,3-b]indole decreases activity EXP 6480464 2-amino-3-methyl-9H-pyrido(2, 3-b)indole results in decreased activity of SLC22A2 protein CTD PMID:30189235 2-Amino-3-methyl-9H-pyrido[2,3-b]indole multiple interactions EXP 6480464 2-amino-3-methyl-9H-pyrido(2, 3-b)indole inhibits the reaction [SLC22A2 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide] CTD PMID:30189235 2-Amino-9H-pyrido[2,3-b]indole multiple interactions EXP 6480464 2-amino-9H-pyrido(2, 3-b)indole inhibits the reaction [SLC22A2 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide] CTD PMID:30189235 2-Amino-9H-pyrido[2,3-b]indole decreases activity EXP 6480464 2-amino-9H-pyrido(2, 3-b)indole results in decreased activity of SLC22A2 protein CTD PMID:30189235 2-hydroxy-2,2-diphenylacetic acid (1,1-dimethyl-3-piperidin-1-iumyl) ester multiple interactions EXP 6480464 mepenzolic acid inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 2-hydroxy-2,2-diphenylacetic acid (1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) ester multiple interactions EXP 6480464 clidinium inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanone multiple interactions EXP 6480464 Tolperisone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine affects expression ISO RGD:61936 6480464 Puromycin Aminonucleoside affects the expression of SLC22A2 mRNA CTD PMID:22005293 3,3',4',5-tetrachlorosalicylanilide multiple interactions EXP 6480464 3 more ... CTD PMID:21599003 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP 6480464 tetrabromobisphenol A inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:27989701 3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine decreases activity EXP 6480464 3 more ... CTD PMID:30189235 3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine multiple interactions EXP 6480464 3 more ... CTD PMID:30189235 3,4-dimethoxybenzoic acid 4-[ethyl-[1-(4-methoxyphenyl)propan-2-yl]amino]butyl ester multiple interactions EXP 6480464 mebeverine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 3-[2-(ethylamino)-1-hydroxyethyl]phenol multiple interactions EXP 6480464 Etilefrine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 3-Amino-1-methyl-5H-pyrido[4,3-b]indole decreases activity EXP 6480464 3-amino-1-methyl-5H-pyrido(4, 3-b)indole results in decreased activity of SLC22A2 protein CTD PMID:30189235 3-Amino-1-methyl-5H-pyrido[4,3-b]indole multiple interactions EXP 6480464 3-amino-1-methyl-5H-pyrido(4 more ... CTD PMID:30189235 4,4'-diaminodiphenylmethane increases expression ISO RGD:62229 6480464 4, 4'-diaminodiphenylmethane results in increased expression of SLC22A2 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 bis(4-hydroxyphenyl)sulfone promotes the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:27989701 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone multiple interactions EXP 6480464 buflomedil inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 4-[1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl]phenol multiple interactions EXP 6480464 Nylidrin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 4-[6-(diaminomethylideneamino)-1-oxohexoxy]benzoic acid ethyl ester multiple interactions EXP 6480464 Gabexate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 4-amino-5-chloro-2-methoxy-N-[1-(phenylmethyl)-4-piperidinyl]benzamide multiple interactions EXP 6480464 clebopride inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 4-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide multiple interactions EXP 6480464 Cisapride inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 5-azaorotic acid decreases expression ISO RGD:61936 6480464 Oxonic Acid results in decreased expression of SLC22A2 protein CTD PMID:19605544 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions EXP 6480464 Omeprazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 6-propyl-2-thiouracil decreases expression ISO RGD:61936 6480464 Propylthiouracil results in decreased expression of SLC22A2 mRNA CTD PMID:24780913 9-aminoacridine multiple interactions EXP 6480464 Aminacrine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol multiple interactions EXP 6480464 Mefloquine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:27504015 acetamiprid decreases activity EXP 6480464 acetamiprid results in decreased activity of SLC22A2 protein CTD PMID:31364238 acetylsalicylic acid affects response to substance EXP 6480464 SLC22A2 polymorphism affects the susceptibility to Aspirin CTD PMID:21346370 aclacinomycin A multiple interactions EXP 6480464 Aclarubicin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 aconitine multiple interactions EXP 6480464 Aconitine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 adapalene multiple interactions EXP 6480464 Adapalene inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 adrenosterone multiple interactions EXP 6480464 adrenosterone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 aflatoxin B1 increases methylation EXP 6480464 Aflatoxin B1 results in increased methylation of SLC22A2 gene CTD PMID:27153756 all-trans-retinoic acid multiple interactions EXP 6480464 Tretinoin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 allopurinol multiple interactions ISO RGD:62229 6480464 Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 mRNA], Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 protein] CTD PMID:21909718 , PMID:22865646 allopurinol multiple interactions ISO RGD:61936 6480464 Allopurinol inhibits the reaction [Fructose results in decreased expression of SLC22A2 mRNA], Allopurinol inhibits the reaction [Fructose results in decreased expression of SLC22A2 protein] CTD PMID:19605544 alprazolam multiple interactions EXP 6480464 Alprazolam inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 alprenolol multiple interactions EXP 6480464 Alprenolol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 amiloride multiple interactions EXP 6480464 Amiloride inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 amitraz multiple interactions EXP 6480464 amitraz inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 amitriptyline multiple interactions EXP 6480464 Amitriptyline inhibits the reaction [SLC22A2 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide] more ... CTD PMID:21599003 more ... amitriptyline decreases activity EXP 6480464 Amitriptyline results in decreased activity of SLC22A2 protein CTD PMID:28629854 , PMID:31364238 ammonium chloride affects expression ISO RGD:61936 6480464 Ammonium Chloride affects the expression of SLC22A2 mRNA CTD PMID:16483693 anastrozole multiple interactions EXP 6480464 anastrozole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 androsterone multiple interactions EXP 6480464 Androsterone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 angelicin increases expression ISO RGD:62229 6480464 angelicin results in increased expression of SLC22A2 mRNA, angelicin results in increased expression of SLC22A2 protein CTD PMID:22173200 antazoline multiple interactions EXP 6480464 Antazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 apomorphine multiple interactions EXP 6480464 Apomorphine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 atrazine affects methylation ISO RGD:61936 6480464 Atrazine affects the methylation of SLC22A2 gene CTD PMID:28931070 atropine multiple interactions EXP 6480464 Atropine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium] more ... CTD PMID:16263091 more ... auranofin multiple interactions EXP 6480464 Auranofin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 azelastine multiple interactions EXP 6480464 azelastine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 azithromycin multiple interactions EXP 6480464 Azithromycin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 bazedoxifene multiple interactions EXP 6480464 bazedoxifene inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 beclomethasone multiple interactions EXP 6480464 Beclomethasone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 benzatropine multiple interactions EXP 6480464 Benztropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 benzethonium chloride multiple interactions EXP 6480464 Benzethonium inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 benzo[a]pyrene increases mutagenesis EXP 6480464 Benzo(a)pyrene results in increased mutagenesis of SLC22A2 gene CTD PMID:25435355 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of SLC22A2 mRNA CTD PMID:32234424 benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of SLC22A2 exon CTD PMID:27901495 benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of SLC22A2 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:62229 6480464 Benzo(a)pyrene results in increased expression of SLC22A2 mRNA CTD PMID:22228805 beta-carboline multiple interactions EXP 6480464 norharman inhibits the reaction [SLC22A2 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide] CTD PMID:30189235 beta-carboline decreases activity EXP 6480464 norharman results in decreased activity of SLC22A2 protein CTD PMID:30189235 bisoprolol multiple interactions EXP 6480464 Bisoprolol inhibits the reaction [SLC22A2 protein results in increased uptake of Metformin] CTD PMID:19740083 bisphenol A decreases expression ISO RGD:61936 6480464 bisphenol A results in decreased expression of SLC22A2 mRNA CTD PMID:25181051 more ... bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of SLC22A2 gene CTD PMID:31601247 bisphenol F multiple interactions EXP 6480464 bisphenol F promotes the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:27989701 bithionol multiple interactions EXP 6480464 Bithionol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 bopindolol multiple interactions EXP 6480464 bopindolol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 bretylium tosylate multiple interactions EXP 6480464 Bretylium Tosylate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 brilliant green multiple interactions EXP 6480464 brilliant green inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 brimonidine tartrate multiple interactions EXP 6480464 Brimonidine Tartrate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 bromhexine multiple interactions EXP 6480464 Bromhexine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 brompheniramine multiple interactions EXP 6480464 Brompheniramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 budesonide multiple interactions EXP 6480464 Budesonide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 bupropion multiple interactions EXP 6480464 Bupropion inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 buspirone multiple interactions EXP 6480464 Buspirone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 butenafine multiple interactions EXP 6480464 butenafine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Butylparaben multiple interactions EXP 6480464 butylparaben inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 butylscopolamine bromide multiple interactions EXP 6480464 Butylscopolammonium Bromide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 cadmium dichloride decreases expression ISO RGD:61936 6480464 Cadmium Chloride results in decreased expression of SLC22A2 mRNA, Cadmium Chloride results in decreased expression of SLC22A2 protein CTD PMID:25588984 capsaicin multiple interactions EXP 6480464 Capsaicin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 carbinoxamine multiple interactions EXP 6480464 carbinoxamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 carvedilol multiple interactions EXP 6480464 Carvedilol inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] more ... CTD PMID:19740083 , PMID:21599003 chlorhexidine multiple interactions EXP 6480464 Chlorhexidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Chlormadinone acetate multiple interactions EXP 6480464 Chlormadinone Acetate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 chlorogenic acid multiple interactions ISO RGD:62229 6480464 Chlorogenic Acid inhibits the reaction [Cisplatin results in decreased expression of SLC22A2 protein] CTD PMID:25043994 chloroquine multiple interactions EXP 6480464 Chloroquine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:27504015 chlorphenamine multiple interactions ISO RGD:61936 6480464 Chlorpheniramine affects the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:12440152 chlorphenamine multiple interactions EXP 6480464 Chlorpheniramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 chlorphenesin carbamate multiple interactions EXP 6480464 chlorphenesin carbamate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 chlorpromazine multiple interactions EXP 6480464 Chlorpromazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 chlorpyrifos multiple interactions EXP 6480464 Chlorpyrifos inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 ciguatoxin CTX1B affects expression ISO RGD:62229 6480464 Ciguatoxins affects the expression of SLC22A2 mRNA CTD PMID:18353800 cilostazol multiple interactions EXP 6480464 cilostazol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 cimetidine multiple interactions EXP 6480464 1-Methyl-4-phenylpyridinium inhibits the reaction [SLC22A2 protein results in increased uptake of Cimetidine] more ... CTD PMID:15496291 more ... cimetidine increases transport ISO RGD:61936 6480464 SLC22A2 protein results in increased transport of Cimetidine CTD PMID:18230276 cimetidine decreases response to substance EXP 6480464 SLC22A2 gene polymorphism results in decreased susceptibility to Cimetidine CTD PMID:22525860 cimetidine increases uptake EXP 6480464 SLC22A2 protein results in increased uptake of Cimetidine CTD PMID:15496291 , PMID:16006492 cimetidine increases uptake ISO RGD:61936 6480464 SLC22A2 protein results in increased uptake of Cimetidine CTD PMID:16006492 cisapride multiple interactions EXP 6480464 Cisapride inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 cisplatin multiple interactions ISO RGD:62229 6480464 [SLC22A2 protein affects the susceptibility to Cisplatin] which affects the expression of SPRR1A protein, Chlorogenic Acid inhibits the reaction [Cisplatin results in decreased expression of SLC22A2 protein] CTD PMID:25043994 , PMID:31493026 cisplatin affects response to substance ISO RGD:62229 6480464 SLC22A2 protein affects the susceptibility to Cisplatin CTD PMID:31493026 cisplatin increases response to substance ISO RGD:62229 6480464 SLC22A2 protein results in increased susceptibility to Cisplatin CTD PMID:21599003 cisplatin multiple interactions EXP 6480464 SLC22A2 gene polymorphism inhibits the reaction [Cisplatin results in increased expression of CST3] CTD PMID:22525860 cisplatin decreases response to substance EXP 6480464 SLC22A2 gene polymorphism results in decreased susceptibility to Cisplatin CTD PMID:22525860 cisplatin affects expression ISO RGD:61936 6480464 Cisplatin affects the expression of SLC22A2 mRNA CTD PMID:22005293 cisplatin decreases expression ISO RGD:62229 6480464 Cisplatin results in decreased expression of SLC22A2 mRNA, Cisplatin results in decreased expression of SLC22A2 protein CTD PMID:25043994 , PMID:31493026 clidinium multiple interactions EXP 6480464 clidinium inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 clomacran multiple interactions EXP 6480464 clomacran inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 clomipramine multiple interactions EXP 6480464 Clomipramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 clonidine multiple interactions EXP 6480464 Clonidine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium], Clonidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:16263091 , PMID:21599003 clonidine (amino form) multiple interactions EXP 6480464 Clonidine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium], Clonidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:16263091 , PMID:21599003 clonidine (imino form) multiple interactions EXP 6480464 Clonidine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium], Clonidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:16263091 , PMID:21599003 clorprenaline multiple interactions EXP 6480464 clorprenaline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 clothianidin decreases activity EXP 6480464 clothianidin results in decreased activity of SLC22A2 protein CTD PMID:31364238 clozapine multiple interactions EXP 6480464 Clozapine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 corticosterone multiple interactions ISO RGD:61936 6480464 Corticosterone inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:9830022 cortisol multiple interactions EXP 6480464 Hydrocortisone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 cortisone multiple interactions EXP 6480464 Cortisone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 crystal violet multiple interactions EXP 6480464 Gentian Violet inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 cyclobenzaprine multiple interactions EXP 6480464 cyclobenzaprine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 cyclosporin A decreases expression ISO RGD:61936 6480464 Cyclosporine results in decreased expression of SLC22A2 mRNA CTD PMID:21865292 cyclosporin A affects expression ISO RGD:61936 6480464 Cyclosporine affects the expression of SLC22A2 mRNA CTD PMID:22005293 cyproheptadine multiple interactions EXP 6480464 Cyproheptadine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 cyromazine multiple interactions EXP 6480464 cyromazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 decabromodiphenyl ether increases expression ISO RGD:61936 6480464 decabromobiphenyl ether results in increased expression of SLC22A2 mRNA CTD PMID:23914054 dequalinium multiple interactions EXP 6480464 Dequalinium inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 desipramine multiple interactions EXP 6480464 Desipramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 desloratadine multiple interactions EXP 6480464 desloratadine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 desoximetasone multiple interactions EXP 6480464 Desoximetasone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 dexbrompheniramine multiple interactions EXP 6480464 dexbrompheniramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 dexchlorpheniramine multiple interactions EXP 6480464 dexchlorpheniramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 dextromethorphan multiple interactions EXP 6480464 Dextromethorphan inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 dextropropoxyphene multiple interactions EXP 6480464 Dextropropoxyphene inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 diazepam multiple interactions EXP 6480464 Diazepam inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 dichlorine multiple interactions ISO RGD:61936 6480464 [Ozone co-treated with Chlorine] results in increased expression of SLC22A2 mRNA CTD PMID:18636392 dicyclomine multiple interactions EXP 6480464 Dicyclomine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 digitonin multiple interactions EXP 6480464 Digitonin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 dimenhydrinate multiple interactions EXP 6480464 Dimenhydrinate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 dimethyl-(phenylmethyl)-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]ammonium multiple interactions EXP 6480464 Benzethonium inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 dioxygen decreases expression ISO RGD:62229 6480464 Oxygen deficiency results in decreased expression of SLC22A2 mRNA CTD PMID:24205000 diphenhydramine multiple interactions EXP 6480464 Diphenhydramine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium], Diphenhydramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:16263091 , PMID:21599003 diphenidol multiple interactions EXP 6480464 diphenidol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 dipyridamole multiple interactions EXP 6480464 Dipyridamole inhibits the reaction [SLC22A2 protein polymorphism results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium], Dipyridamole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 disodium selenite decreases expression EXP 6480464 Sodium Selenite results in decreased expression of SLC22A2 mRNA CTD PMID:18175754 disopyramide multiple interactions ISO RGD:61936 6480464 Disopyramide affects the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:12440152 disopyramide multiple interactions EXP 6480464 Disopyramide inhibits the reaction [SLC22A2 protein polymorphism results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium], Disopyramide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 domperidone multiple interactions EXP 6480464 Domperidone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 donepezil hydrochloride multiple interactions EXP 6480464 Donepezil inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 dopamine multiple interactions ISO RGD:61936 6480464 Dopamine affects the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:12440152 doxazosin multiple interactions EXP 6480464 Doxazosin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 doxepin multiple interactions EXP 6480464 Doxepin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 doxepin multiple interactions ISO RGD:61936 6480464 Doxepin inhibits the reaction [SLC22A2 protein results in increased uptake of mepiquat] CTD PMID:33639197 droperidol multiple interactions EXP 6480464 Droperidol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 dyclonine multiple interactions EXP 6480464 dyclonine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 econazole multiple interactions EXP 6480464 Econazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 epalrestat multiple interactions EXP 6480464 epalrestat inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Eperisone hydrochloride multiple interactions EXP 6480464 eperisone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 epinastine multiple interactions EXP 6480464 epinastine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 estrone multiple interactions EXP 6480464 Estrone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 ethidium increases uptake EXP 6480464 SLC22A2 protein results in increased uptake of Ethidium CTD PMID:19357179 ethidium multiple interactions EXP 6480464 1-Methyl-4-phenylpyridinium inhibits the reaction [SLC22A2 protein results in increased uptake of Ethidium] more ... CTD PMID:19357179 ethidium affects uptake ISO RGD:62229 6480464 SLC22A2 protein affects the uptake of Ethidium CTD PMID:19357179 exemestane multiple interactions EXP 6480464 exemestane inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 famotidine increases uptake EXP 6480464 SLC22A2 protein results in increased uptake of Famotidine CTD PMID:16006492 famotidine increases uptake ISO RGD:61936 6480464 SLC22A2 protein results in increased uptake of Famotidine CTD PMID:16006492 famotidine multiple interactions EXP 6480464 Famotidine inhibits the reaction [SLC22A2 protein affects the transport of Tetraethylammonium] more ... CTD PMID:15496291 more ... fenitrothion multiple interactions EXP 6480464 Fenitrothion inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 finasteride multiple interactions EXP 6480464 Finasteride inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 flumazenil multiple interactions EXP 6480464 Flumazenil inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 fluorometholone multiple interactions EXP 6480464 Fluorometholone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 fluoxetine multiple interactions EXP 6480464 Fluoxetine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 fluphenazine multiple interactions EXP 6480464 Fluphenazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Flurandrenolide multiple interactions EXP 6480464 Flurandrenolone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 formononetin decreases expression ISO RGD:61936 6480464 formononetin results in decreased expression of SLC22A2 mRNA CTD PMID:28414026 fructose decreases expression ISO RGD:61936 6480464 Fructose results in decreased expression of SLC22A2 mRNA, Fructose results in decreased expression of SLC22A2 protein CTD PMID:19605544 fructose multiple interactions ISO RGD:61936 6480464 Allopurinol inhibits the reaction [Fructose results in decreased expression of SLC22A2 mRNA] more ... CTD PMID:19605544 fulvestrant multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of SLC22A2 gene CTD PMID:31601247 genistein increases expression ISO RGD:62229 6480464 Genistein results in increased expression of SLC22A2 mRNA CTD PMID:32186404 gentamycin increases transport EXP 6480464 SLC22A2 protein results in increased transport of Gentamicins CTD PMID:27401566 gentamycin affects expression ISO RGD:61936 6480464 Gentamicins affects the expression of SLC22A2 mRNA CTD PMID:22005293 gentamycin decreases expression ISO RGD:61936 6480464 Gentamicins results in decreased expression of SLC22A2 mRNA CTD PMID:22061828 Glu-P-1 multiple interactions EXP 6480464 2-amino-6-methyldipyrido(1 more ... CTD PMID:30189235 Glu-P-1 decreases activity EXP 6480464 2-amino-6-methyldipyrido(1 more ... CTD PMID:30189235 Glu-P-2 decreases activity EXP 6480464 Glu-P-2 results in decreased activity of SLC22A2 protein CTD PMID:30189235 Glu-P-2 multiple interactions EXP 6480464 Glu-P-2 inhibits the reaction [SLC22A2 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide] CTD PMID:30189235 glycyrrhizinic acid multiple interactions EXP 6480464 Glycyrrhizic Acid inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 granisetron multiple interactions EXP 6480464 Granisetron inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Guanabenz multiple interactions EXP 6480464 Guanabenz inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Guanfacine multiple interactions EXP 6480464 Guanfacine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Halcinonide multiple interactions EXP 6480464 Halcinonide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 haloperidol multiple interactions EXP 6480464 Haloperidol inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 harman multiple interactions EXP 6480464 harman inhibits the reaction [SLC22A2 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide] CTD PMID:30189235 harman decreases activity EXP 6480464 harman results in decreased activity of SLC22A2 protein CTD PMID:30189235 Homatropine multiple interactions EXP 6480464 homatropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 hydralazine multiple interactions EXP 6480464 Hydralazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 hydroxyzine multiple interactions EXP 6480464 Hydroxyzine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 idebenone multiple interactions EXP 6480464 idebenone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 imidacloprid decreases activity EXP 6480464 imidacloprid results in decreased activity of SLC22A2 protein CTD PMID:31364238 imipramine multiple interactions EXP 6480464 Imipramine inhibits the reaction [SLC22A2 protein polymorphism results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium], Imipramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 imperatorin increases expression ISO RGD:62229 6480464 imperatorin results in increased expression of SLC22A2 protein CTD PMID:22173200 imperatorin decreases expression ISO RGD:62229 6480464 imperatorin results in decreased expression of SLC22A2 mRNA CTD PMID:22173200 indapamide multiple interactions EXP 6480464 Indapamide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 indometacin decreases activity EXP 6480464 Indomethacin results in decreased activity of SLC22A2 protein CTD PMID:12388633 ipratropium multiple interactions EXP 6480464 Ipratropium inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 isoimperatorin increases expression ISO RGD:62229 6480464 isoimperatorin results in increased expression of SLC22A2 protein CTD PMID:22173200 isoimperatorin decreases expression ISO RGD:62229 6480464 isoimperatorin results in decreased expression of SLC22A2 mRNA CTD PMID:22173200 Isopropamide iodide multiple interactions EXP 6480464 isopropamide iodide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 kainic acid multiple interactions EXP 6480464 Kainic Acid inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 ketotifen multiple interactions EXP 6480464 Ketotifen inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Lafutidine multiple interactions EXP 6480464 lafutidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 lamivudine increases uptake EXP 6480464 SLC22A2 protein results in increased uptake of Lamivudine CTD PMID:19141712 lansoprazole multiple interactions EXP 6480464 Lansoprazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 letrozole multiple interactions EXP 6480464 letrozole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 leuprolide multiple interactions EXP 6480464 Leuprolide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Licochalcone B decreases expression EXP 6480464 licochalcone B results in decreased expression of SLC22A2 mRNA CTD PMID:33647349 lidocaine multiple interactions EXP 6480464 Lidocaine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 lisuride multiple interactions EXP 6480464 Lisuride inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 loperamide multiple interactions EXP 6480464 Loperamide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 lysergol multiple interactions EXP 6480464 lysergol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 malathion multiple interactions EXP 6480464 Malathion inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 maneb multiple interactions ISO RGD:62229 6480464 [Maneb co-treated with Paraquat] results in decreased expression of SLC22A2 mRNA, Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SLC22A2 mRNA] CTD PMID:23963992 mangiferin increases expression ISO RGD:62229 6480464 mangiferin results in increased expression of SLC22A2 mRNA CTD PMID:21348301 Maprotiline multiple interactions EXP 6480464 Maprotiline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 mechlorethamine multiple interactions EXP 6480464 Mechlorethamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 medroxyprogesterone multiple interactions EXP 6480464 Medroxyprogesterone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 mefloquine multiple interactions EXP 6480464 Mefloquine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:27504015 megestrol acetate multiple interactions EXP 6480464 Megestrol Acetate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 MeIQ decreases activity EXP 6480464 2-amino-3 more ... CTD PMID:30189235 MeIQ multiple interactions EXP 6480464 2-amino-3 more ... CTD PMID:30189235 MeIQx multiple interactions EXP 6480464 2-amino-3 more ... CTD PMID:30189235 MeIQx decreases activity EXP 6480464 2-amino-3 more ... CTD PMID:30189235 melatonin multiple interactions ISO RGD:62229 6480464 Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SLC22A2 mRNA] CTD PMID:23963992 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Mepenzolate multiple interactions EXP 6480464 mepenzolic acid inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 mepiquat increases uptake ISO RGD:61936 6480464 SLC22A2 protein results in increased uptake of mepiquat CTD PMID:33639197 mepiquat multiple interactions ISO RGD:61936 6480464 Doxepin inhibits the reaction [SLC22A2 protein results in increased uptake of mepiquat], Verapamil inhibits the reaction [SLC22A2 protein results in increased uptake of mepiquat] CTD PMID:33639197 mepyramine multiple interactions EXP 6480464 Pyrilamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 mercury dichloride multiple interactions EXP 6480464 [Mercuric Chloride results in decreased activity of SLC22A2 protein] which results in decreased uptake of Tetraethylammonium CTD PMID:17287197 mercury dichloride decreases expression ISO RGD:61936 6480464 Mercuric Chloride results in decreased expression of SLC22A2 mRNA CTD PMID:28536007 mercury dichloride decreases activity EXP 6480464 Mercuric Chloride results in decreased activity of SLC22A2 protein CTD PMID:17287197 Mestanolone multiple interactions EXP 6480464 mestanolone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 metformin multiple interactions EXP 6480464 Bisoprolol inhibits the reaction [SLC22A2 protein results in increased uptake of Metformin] more ... CTD PMID:16141367 more ... metformin increases transport ISO RGD:61936 6480464 SLC22A2 protein results in increased transport of Metformin CTD PMID:18230276 metformin increases uptake ISO RGD:62229 6480464 SLC22A2 protein results in increased uptake of Metformin CTD PMID:24001450 metformin increases uptake EXP 6480464 SLC22A2 protein results in increased uptake of Metformin CTD PMID:19740083 more ... metformin multiple interactions ISO RGD:62229 6480464 Ondansetron inhibits the reaction [SLC22A2 protein results in increased uptake of Metformin] CTD PMID:24001450 metformin decreases transport EXP 6480464 SLC22A2 protein mutant form results in decreased transport of Metformin CTD PMID:18728938 metformin affects transport EXP 6480464 SLC22A2 protein affects the transport of Metformin CTD PMID:18728938 methoxsalen decreases expression ISO RGD:62229 6480464 Methoxsalen results in decreased expression of SLC22A2 mRNA CTD PMID:22173200 methoxsalen increases expression ISO RGD:62229 6480464 Methoxsalen results in increased expression of SLC22A2 protein CTD PMID:22173200 methyltestosterone multiple interactions EXP 6480464 Methyltestosterone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 metoclopramide multiple interactions EXP 6480464 Metoclopramide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 metoprolol multiple interactions EXP 6480464 Metoprolol inhibits the reaction [SLC22A2 protein results in increased uptake of Metformin] CTD PMID:19740083 mianserin multiple interactions EXP 6480464 Mianserin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 miconazole multiple interactions EXP 6480464 Miconazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 mirtazapine multiple interactions EXP 6480464 mirtazapine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 monobenzone multiple interactions EXP 6480464 monobenzone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 mosapride citrate dihydrate multiple interactions EXP 6480464 mosapride inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Moxonidine multiple interactions EXP 6480464 moxonidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 mycophenolic acid multiple interactions EXP 6480464 Mycophenolic Acid inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 myrtecaine multiple interactions EXP 6480464 myrtecaine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 N,N-diethyl-m-toluamide multiple interactions ISO RGD:61936 6480464 [Permethrin co-treated with DEET] results in increased methylation of SLC22A2 gene CTD PMID:33148267 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 1-Methyl-4-phenylpyridinium inhibits the reaction [SLC22A2 protein results in increased uptake of Cimetidine] more ... CTD PMID:12110607 more ... N-methyl-4-phenylpyridinium decreases uptake EXP 6480464 SLC22A2 gene polymorphism results in decreased uptake of 1-Methyl-4-phenylpyridinium CTD PMID:17220237 N-methyl-4-phenylpyridinium increases uptake EXP 6480464 SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium CTD PMID:12110607 more ... N-methyl-4-phenylpyridinium increases transport EXP 6480464 SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium CTD PMID:16211406 , PMID:16263091 N-methyl-4-phenylpyridinium increases import EXP 6480464 SLC22A2 results in increased import of 1-Methyl-4-phenylpyridinium CTD PMID:9260930 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:61936 6480464 1-Methyl-4-phenylpyridinium affects the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:12440152 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine increases uptake EXP 6480464 SLC22A2 protein results in increased uptake of Ranitidine CTD PMID:16006492 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine increases uptake ISO RGD:61936 6480464 SLC22A2 protein results in increased uptake of Ranitidine CTD PMID:16006492 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium], Ranitidine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:16141367 , PMID:16263091 nalbuphine multiple interactions EXP 6480464 Nalbuphine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 nandrolone multiple interactions EXP 6480464 Nandrolone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 naphthalene decreases expression ISO RGD:61936 6480464 naphthalene analog results in decreased expression of SLC22A2 mRNA CTD PMID:24976557 naproxen decreases activity EXP 6480464 Naproxen results in decreased activity of SLC22A2 protein CTD PMID:12388633 nefazodone multiple interactions EXP 6480464 nefazodone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 nicardipine multiple interactions EXP 6480464 Nicardipine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 nicotine multiple interactions EXP 6480464 Nicotine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 nicotine affects response to substance EXP 6480464 SLC22A2 gene SNP affects the susceptibility to Nicotine CTD PMID:25143296 Nifekalant multiple interactions EXP 6480464 nifekalant inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 nimetazepam multiple interactions EXP 6480464 nimetazepam inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 nitenpyram decreases activity EXP 6480464 nitenpyram results in decreased activity of SLC22A2 protein CTD PMID:31364238 nocodazole multiple interactions EXP 6480464 Nocodazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 norethisterone multiple interactions EXP 6480464 Norethindrone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 norfloxacin multiple interactions EXP 6480464 Norfloxacin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 nortriptyline multiple interactions EXP 6480464 Nortriptyline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 ochratoxin A decreases expression ISO RGD:61936 6480464 ochratoxin A results in decreased expression of SLC22A2 mRNA, ochratoxin A results in decreased expression of SLC22A2 protein CTD PMID:12700408 more ... ochratoxin A multiple interactions ISO RGD:61936 6480464 SLC22A2 protein affects the reaction [ochratoxin A results in increased expression of CASP3 mRNA] more ... CTD PMID:30120945 ochratoxin A increases expression ISO RGD:61936 6480464 ochratoxin A results in increased expression of SLC22A2 mRNA, ochratoxin A results in increased expression of SLC22A2 protein CTD PMID:30120945 olanzapine multiple interactions EXP 6480464 olanzapine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 omeprazole multiple interactions EXP 6480464 Omeprazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Ondansetron multiple interactions ISO RGD:62229 6480464 Ondansetron inhibits the reaction [SLC22A2 protein results in increased uptake of Metformin] CTD PMID:24001450 Ondansetron multiple interactions EXP 6480464 Ondansetron inhibits the reaction [SLC22A2 protein polymorphism results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] more ... CTD PMID:21599003 , PMID:24001450 orlistat multiple interactions EXP 6480464 orlistat inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 orphenadrine multiple interactions EXP 6480464 Orphenadrine inhibits the reaction [SLC22A2 protein polymorphism results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium], Orphenadrine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 oxaliplatin increases response to substance EXP 6480464 SLC22A2 protein results in increased susceptibility to Oxaliplatin CTD PMID:34252480 oxaliplatin increases import EXP 6480464 SLC22A2 protein results in increased import of Oxaliplatin CTD PMID:34252480 oxaliplatin multiple interactions EXP 6480464 tetrahydropalmatine inhibits the reaction [SLC22A2 protein results in increased import of Oxaliplatin] CTD PMID:34252480 oxatomide multiple interactions EXP 6480464 oxatomide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 oxiconazole multiple interactions EXP 6480464 oxiconazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 oxybuprocaine multiple interactions EXP 6480464 benoxinate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 oxybutynin multiple interactions EXP 6480464 oxybutynin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 oxymetazoline multiple interactions EXP 6480464 Oxymetazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 oxymetholone multiple interactions EXP 6480464 Oxymetholone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 ozone multiple interactions ISO RGD:61936 6480464 [Ozone co-treated with Chlorine] results in increased expression of SLC22A2 mRNA CTD PMID:18636392 p-aminohippuric acid multiple interactions EXP 6480464 p-Aminohippuric Acid inhibits the reaction [SLC22A2 protein results in increased uptake of Cimetidine] CTD PMID:15496291 paraquat affects uptake EXP 6480464 SLC22A2 protein affects the uptake of Paraquat CTD PMID:17495125 paraquat multiple interactions ISO RGD:62229 6480464 [Maneb co-treated with Paraquat] results in decreased expression of SLC22A2 mRNA, Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SLC22A2 mRNA] CTD PMID:23963992 paraquat affects uptake ISO RGD:61936 6480464 SLC22A2 protein affects the uptake of Paraquat CTD PMID:17495125 paraquat increases response to substance EXP 6480464 SLC22A2 protein results in increased susceptibility to Paraquat CTD PMID:17495125 paroxetine multiple interactions EXP 6480464 Paroxetine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 parthenolide multiple interactions EXP 6480464 parthenolide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 pecazine multiple interactions EXP 6480464 mepazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 pentamidine multiple interactions EXP 6480464 Pentamidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 perfluorodecalin multiple interactions EXP 6480464 perfluorodecalin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 pergolide multiple interactions EXP 6480464 Pergolide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 perhexiline multiple interactions EXP 6480464 Perhexiline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 permethrin multiple interactions ISO RGD:61936 6480464 [Permethrin co-treated with DEET] results in increased methylation of SLC22A2 gene CTD PMID:33148267 perphenazine multiple interactions EXP 6480464 Perphenazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Phenelzine multiple interactions EXP 6480464 Phenelzine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 phenformin multiple interactions EXP 6480464 Phenformin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Phenoxybenzamine multiple interactions EXP 6480464 Phenoxybenzamine inhibits the reaction [SLC22A2 protein affects the transport of Metformin] more ... CTD PMID:12110607 more ... Phenoxybenzamine decreases activity EXP 6480464 Phenoxybenzamine results in decreased activity of SLC22A2 protein CTD PMID:12110607 phentolamine multiple interactions EXP 6480464 Phentolamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 phenyltoloxamine multiple interactions EXP 6480464 phenyltoloxamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 PhIP multiple interactions EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine inhibits the reaction [SLC22A2 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide] CTD PMID:30189235 PhIP decreases activity EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in decreased activity of SLC22A2 protein CTD PMID:30189235 pioglitazone multiple interactions EXP 6480464 pioglitazone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Piracetam multiple interactions EXP 6480464 Piracetam inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 piroxicam decreases activity EXP 6480464 Piroxicam results in decreased activity of SLC22A2 protein CTD PMID:12388633 Potassium 2,6-dihydroxytriazinecarboxylate multiple interactions ISO RGD:62229 6480464 Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 mRNA] more ... CTD PMID:21909718 more ... Potassium 2,6-dihydroxytriazinecarboxylate decreases expression ISO RGD:62229 6480464 potassium oxonate results in decreased expression of SLC22A2 mRNA, potassium oxonate results in decreased expression of SLC22A2 protein CTD PMID:21909718 more ... pralidoxime multiple interactions EXP 6480464 pralidoxime inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 prazosin multiple interactions EXP 6480464 Prazosin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 prednisone multiple interactions EXP 6480464 Prednisone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 pridinol multiple interactions EXP 6480464 pridinol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 primaquine multiple interactions EXP 6480464 Primaquine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 prinomastat multiple interactions EXP 6480464 prinomastat inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 probenecid multiple interactions ISO RGD:62229 6480464 Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 mRNA], Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 protein] CTD PMID:22865646 , PMID:22967667 procyclidine multiple interactions EXP 6480464 Procyclidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 progesterone multiple interactions ISO RGD:61936 6480464 Progesterone inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:9830022 promazine multiple interactions EXP 6480464 Promazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Propantheline multiple interactions EXP 6480464 Propantheline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Proparacaine multiple interactions EXP 6480464 proxymetacaine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 propranolol multiple interactions EXP 6480464 Propranolol inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium], Propranolol inhibits the reaction [SLC22A2 protein results in increased uptake of Metformin] CTD PMID:19740083 psoralen increases expression ISO RGD:62229 6480464 Ficusin results in increased expression of SLC22A2 mRNA, Ficusin results in increased expression of SLC22A2 protein CTD PMID:22173200 pyrimethamine multiple interactions EXP 6480464 Pyrimethamine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:27504015 quercetin multiple interactions ISO RGD:62229 6480464 Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 mRNA], Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 protein] CTD PMID:21909718 quercetin multiple interactions ISO RGD:61936 6480464 Quercetin inhibits the reaction [Fructose results in decreased expression of SLC22A2 mRNA], Quercetin inhibits the reaction [Fructose results in decreased expression of SLC22A2 protein] CTD PMID:19605544 quinidine multiple interactions EXP 6480464 Quinidine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium], Quinidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:16141367 , PMID:21599003 quinine multiple interactions EXP 6480464 Quinine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium] more ... CTD PMID:16263091 more ... quinine decreases activity EXP 6480464 Quinine results in decreased activity of SLC22A2 protein CTD PMID:31830554 rabeprazole multiple interactions EXP 6480464 Rabeprazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 raloxifene multiple interactions EXP 6480464 Raloxifene Hydrochloride inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 ranitidine increases uptake EXP 6480464 SLC22A2 protein results in increased uptake of Ranitidine CTD PMID:16006492 ranitidine increases uptake ISO RGD:61936 6480464 SLC22A2 protein results in increased uptake of Ranitidine CTD PMID:16006492 ranitidine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium], Ranitidine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:16141367 , PMID:16263091 resveratrol multiple interactions EXP 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of SLC22A2 mRNA CTD PMID:23557933 rutin multiple interactions ISO RGD:61936 6480464 Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A2 mRNA], Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A2 protein] CTD PMID:19605544 semustine multiple interactions EXP 6480464 Semustine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 sildenafil citrate multiple interactions EXP 6480464 Sildenafil Citrate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 sodium dichromate increases expression ISO RGD:61936 6480464 sodium bichromate results in increased expression of SLC22A2 mRNA CTD PMID:12325037 sparteine multiple interactions EXP 6480464 Sparteine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 spiperone multiple interactions EXP 6480464 Spiperone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 spironolactone multiple interactions EXP 6480464 Spironolactone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 streptozocin decreases expression ISO RGD:61936 6480464 Streptozocin results in decreased expression of SLC22A2 protein CTD PMID:19605544 strychnine multiple interactions EXP 6480464 Strychnine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 sulconazole multiple interactions EXP 6480464 sulconazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 sulindac decreases activity EXP 6480464 Sulindac results in decreased activity of SLC22A2 protein CTD PMID:12388633 tacrine multiple interactions EXP 6480464 Tacrine inhibits the reaction [SLC22A2 protein polymorphism results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium], Tacrine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Tegafur multiple interactions EXP 6480464 Tegafur inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 telmisartan multiple interactions EXP 6480464 telmisartan inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 terbutaline multiple interactions EXP 6480464 Terbutaline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 terconazole multiple interactions EXP 6480464 terconazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 testosterone multiple interactions ISO RGD:61936 6480464 Testosterone inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:9830022 tetracaine multiple interactions EXP 6480464 Tetracaine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 tetrachloromethane increases expression ISO RGD:61936 6480464 Carbon Tetrachloride results in increased expression of SLC22A2 mRNA CTD PMID:16644059 tetraethylammonium multiple interactions EXP 6480464 3-amino-1 more ... CTD PMID:15496291 more ... tetraethylammonium increases uptake EXP 6480464 SLC22A2 protein results in increased uptake of Tetraethylammonium CTD PMID:16006492 more ... tetraethylammonium decreases uptake EXP 6480464 SLC22A2 gene polymorphism results in decreased uptake of Tetraethylammonium CTD PMID:17220237 tetraethylammonium increases uptake ISO RGD:61936 6480464 SLC22A2 protein results in increased uptake of Tetraethylammonium CTD PMID:12440152 more ... tetraethylammonium increases import EXP 6480464 SLC22A2 protein results in increased import of Tetraethylammonium, SLC22A2 results in increased import of Tetraethylammonium CTD PMID:28629854 more ... tetraethylammonium affects transport EXP 6480464 SLC22A2 protein affects the transport of Tetraethylammonium CTD PMID:15496291 , PMID:16141367 tetraethylammonium multiple interactions ISO RGD:61936 6480464 1-Methyl-4-phenylpyridinium affects the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] more ... CTD PMID:12440152 , PMID:9830022 tetrahydropalmatine multiple interactions EXP 6480464 tetrahydropalmatine inhibits the reaction [SLC22A2 protein results in increased import of Oxaliplatin] CTD PMID:34252480 tetryzoline multiple interactions EXP 6480464 tetrahydrozoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 thalidomide multiple interactions EXP 6480464 Thalidomide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 thiacloprid decreases activity EXP 6480464 thiacloprid metabolite results in decreased activity of SLC22A2 protein, thiacloprid results in decreased activity of SLC22A2 protein CTD PMID:31364238 thiamethoxam decreases activity EXP 6480464 Thiamethoxam results in decreased activity of SLC22A2 protein CTD PMID:31364238 thioridazine multiple interactions EXP 6480464 Thioridazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 tolazoline multiple interactions EXP 6480464 Tolazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 tolterodine tartrate multiple interactions EXP 6480464 Tolterodine Tartrate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 trazodone multiple interactions EXP 6480464 Trazodone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 triamcinolone acetonide multiple interactions EXP 6480464 Triamcinolone Acetonide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 triazolam multiple interactions EXP 6480464 Triazolam inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 Trihexyphenidyl multiple interactions EXP 6480464 Trihexyphenidyl inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 trimellitic anhydride decreases expression ISO RGD:62229 6480464 trimellitic anhydride results in decreased expression of SLC22A2 mRNA CTD PMID:19042947 trimipramine multiple interactions EXP 6480464 Trimipramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Tripelennamine multiple interactions EXP 6480464 Tripelennamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions EXP 6480464 Atropine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium] more ... CTD PMID:16263091 more ... tropisetron multiple interactions EXP 6480464 tropisetron inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 trospium chloride decreases activity EXP 6480464 trospium chloride results in decreased activity of SLC22A2 protein CTD PMID:25466967 valdecoxib multiple interactions EXP 6480464 valdecoxib inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of SLC22A2 mRNA CTD PMID:25979313 vancomycin multiple interactions ISO RGD:61936 6480464 JBP 485 inhibits the reaction [Vancomycin results in decreased expression of SLC22A2 mRNA], JBP 485 inhibits the reaction [Vancomycin results in decreased expression of SLC22A2 protein] CTD PMID:29964132 vancomycin decreases expression ISO RGD:61936 6480464 Vancomycin results in decreased expression of SLC22A2 mRNA, Vancomycin results in decreased expression of SLC22A2 protein CTD PMID:29964132 varenicline affects response to substance EXP 6480464 SLC22A2 gene SNP affects the susceptibility to Varenicline CTD PMID:25143296 verapamil multiple interactions EXP 6480464 Verapamil inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 verapamil multiple interactions ISO RGD:61936 6480464 Verapamil inhibits the reaction [SLC22A2 protein results in increased uptake of mepiquat] CTD PMID:33639197 VX-745 multiple interactions EXP 6480464 VX-745 inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 Xylometazoline multiple interactions EXP 6480464 xylometazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 zafirlukast multiple interactions EXP 6480464 zafirlukast inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 zolpidem multiple interactions EXP 6480464 zolpidem inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003
