DDIT4L (DNA damage inducible transcript 4 like) - Rat Genome Database

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Gene: DDIT4L (DNA damage inducible transcript 4 like) Homo sapiens
Analyze
Symbol: DDIT4L
Name: DNA damage inducible transcript 4 like
RGD ID: 1342784
HGNC Page HGNC:30555
Description: Predicted to be involved in negative regulation of signal transduction. Predicted to be located in cytoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA damage-inducible transcript 4-like protein; DNA-damage-inducible transcript 4-like; HIF-1 responsive protein RTP801-like; homolog of mouse SMHS1; REDD-2; REDD2; regulated in development and DNA damage response 2; Rtp801L
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384100,185,870 - 100,190,468 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4100,185,870 - 100,190,782 (-)EnsemblGRCh38hg38GRCh38
GRCh374101,107,027 - 101,111,625 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364101,326,050 - 101,330,636 (-)NCBINCBI36Build 36hg18NCBI36
Build 344101,464,206 - 101,468,791NCBI
Celera498,405,052 - 98,409,638 (-)NCBICelera
Cytogenetic Map4q24NCBI
HuRef496,845,264 - 96,850,266 (-)NCBIHuRef
CHM1_14101,083,602 - 101,088,230 (-)NCBICHM1_1
T2T-CHM13v2.04103,501,503 - 103,506,101 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
genetic disease  (IAGP)
melanoma  (EXP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
1H-pyrazole  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-acetamidofluorene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxyphenyl retinamide  (ISO)
7,12-dimethyltetraphene  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
beta-D-glucosamine  (ISO)
bisphenol A  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
cadmium sulfate  (ISO)
carbamazepine  (EXP)
cefaloridine  (ISO)
chloroprene  (ISO)
choline  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
curcumin  (EXP,ISO)
cyclosporin A  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
diethyl maleate  (ISO)
diethylstilbestrol  (ISO)
disodium selenite  (EXP)
dorsomorphin  (EXP)
endosulfan  (ISO)
entinostat  (EXP)
ethanol  (ISO)
flutamide  (ISO)
folic acid  (ISO)
furan  (ISO)
glycidol  (ISO)
hydroxyurea  (ISO)
inulin  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (EXP)
menadione  (ISO)
metformin  (EXP)
methapyrilene  (ISO)
methylmercury chloride  (EXP)
microcystin-LR  (ISO)
mitomycin C  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (EXP)
p-chloromercuribenzoic acid  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (EXP)
pioglitazone  (EXP)
pirinixic acid  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
SB 431542  (EXP)
silicon dioxide  (EXP)
sirolimus  (ISO)
sodium arsenite  (ISO)
Soman  (ISO)
sotorasib  (EXP)
sunitinib  (EXP)
tacrolimus hydrate  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
trametinib  (EXP)
trichloroethene  (ISO)
trichostatin A  (EXP)
triclosan  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
triptonide  (ISO)
valproic acid  (EXP)
zearalenone  (EXP)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:12453409   PMID:14702039   PMID:15308555   PMID:15632201   PMID:16189514   PMID:16344560   PMID:17207965   PMID:19268525   PMID:19491193   PMID:19616115   PMID:25416956   PMID:25814554  
PMID:26030842   PMID:27107012   PMID:27107014   PMID:28246202   PMID:28514442   PMID:31515488   PMID:32296183   PMID:32814053   PMID:33961781   PMID:35914814   PMID:36217029  


Genomics

Comparative Map Data
DDIT4L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384100,185,870 - 100,190,468 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4100,185,870 - 100,190,782 (-)EnsemblGRCh38hg38GRCh38
GRCh374101,107,027 - 101,111,625 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364101,326,050 - 101,330,636 (-)NCBINCBI36Build 36hg18NCBI36
Build 344101,464,206 - 101,468,791NCBI
Celera498,405,052 - 98,409,638 (-)NCBICelera
Cytogenetic Map4q24NCBI
HuRef496,845,264 - 96,850,266 (-)NCBIHuRef
CHM1_14101,083,602 - 101,088,230 (-)NCBICHM1_1
T2T-CHM13v2.04103,501,503 - 103,506,101 (-)NCBIT2T-CHM13v2.0
Ddit4l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393137,329,433 - 137,334,093 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3137,327,373 - 137,334,094 (+)EnsemblGRCm39 Ensembl
GRCm383137,623,672 - 137,628,332 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3137,621,612 - 137,628,333 (+)EnsemblGRCm38mm10GRCm38
MGSCv373137,286,636 - 137,291,296 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363137,561,123 - 137,565,719 (+)NCBIMGSCv36mm8
Celera3144,044,354 - 144,049,027 (+)NCBICelera
Cytogenetic Map3G3NCBI
cM Map363.81NCBI
Ddit4l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82228,800,831 - 228,804,478 (+)NCBIGRCr8
mRatBN7.22226,128,273 - 226,131,044 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2226,128,276 - 226,131,375 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2233,871,078 - 233,873,849 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02231,770,838 - 231,773,609 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02226,635,456 - 226,638,227 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02242,882,219 - 242,885,088 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2242,882,306 - 242,885,131 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02261,430,156 - 261,433,647 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42235,130,697 - 235,133,417 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2218,297,989 - 218,300,862 (+)NCBICelera
Cytogenetic Map2q43NCBI
Ddit4l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554967,618,731 - 7,622,180 (+)NCBIChiLan1.0ChiLan1.0
DDIT4L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2398,264,882 - 98,273,862 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1498,551,071 - 98,560,055 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0492,606,473 - 92,615,421 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14103,268,048 - 103,272,666 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4103,268,048 - 103,272,666 (-)Ensemblpanpan1.1panPan2
DDIT4L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13222,062,630 - 22,067,364 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3222,064,393 - 22,068,562 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3219,827,798 - 19,833,447 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03222,284,651 - 22,290,302 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3222,283,572 - 22,289,375 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13222,261,135 - 22,266,777 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03222,046,970 - 22,052,613 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03217,814,385 - 17,820,036 (+)NCBIUU_Cfam_GSD_1.0
Ddit4l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530119,480,437 - 19,485,057 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365202,823,885 - 2,828,698 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365202,823,896 - 2,828,687 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDIT4L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8120,371,769 - 120,376,441 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18120,371,724 - 120,376,444 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28129,550,404 - 129,555,119 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDIT4L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1748,311,147 - 48,315,706 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl748,311,161 - 48,315,630 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603726,785,094 - 26,790,407 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in DDIT4L
8 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 4q22.2-32.3(chr4:92913386-165299707)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051775]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051775]|See cases [RCV000051775] Chr4:92913386..165299707 [GRCh38]
Chr4:93834537..166220859 [GRCh37]
Chr4:94053560..166440309 [NCBI36]
Chr4:4q22.2-32.3
pathogenic
GRCh38/hg38 4q22.3-28.3(chr4:96092893-136410207)x3 copy number gain See cases [RCV000051776] Chr4:96092893..136410207 [GRCh38]
Chr4:97014044..137331362 [GRCh37]
Chr4:97233067..137550812 [NCBI36]
Chr4:4q22.3-28.3
pathogenic
GRCh38/hg38 4q21.21-24(chr4:80427023-100855441)x1 copy number loss See cases [RCV000137269] Chr4:80427023..100855441 [GRCh38]
Chr4:81348177..101776598 [GRCh37]
Chr4:81567201..101995621 [NCBI36]
Chr4:4q21.21-24
pathogenic
GRCh38/hg38 4q22.1-24(chr4:92610413-101521991)x1 copy number loss See cases [RCV000140412] Chr4:92610413..101521991 [GRCh38]
Chr4:93531564..102443148 [GRCh37]
Chr4:93750587..102662171 [NCBI36]
Chr4:4q22.1-24
pathogenic
GRCh38/hg38 4q23-24(chr4:100021886-100301285)x1 copy number loss See cases [RCV000143561] Chr4:100021886..100301285 [GRCh38]
Chr4:100943043..101222442 [GRCh37]
Chr4:101162066..101441465 [NCBI36]
Chr4:4q23-24
likely benign|uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4q21.23-24(chr4:85805268-103678797)x1 copy number loss See cases [RCV000445741] Chr4:85805268..103678797 [GRCh37]
Chr4:4q21.23-24
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4q22.1-24(chr4:92201567-103043808)x1 copy number loss See cases [RCV000511194] Chr4:92201567..103043808 [GRCh37]
Chr4:4q22.1-24
pathogenic
GRCh37/hg19 4q22.1-35.2(chr4:93071152-190957473)x3 copy number gain See cases [RCV000510970] Chr4:93071152..190957473 [GRCh37]
Chr4:4q22.1-35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4q22.2-24(chr4:94692345-101308220)x1 copy number loss not provided [RCV001259285] Chr4:94692345..101308220 [GRCh37]
Chr4:4q22.2-24
likely pathogenic
GRCh37/hg19 4q22.3-25(chr4:95490755-109977216)x3 copy number gain not provided [RCV001827745] Chr4:95490755..109977216 [GRCh37]
Chr4:4q22.3-25
likely pathogenic
GRCh37/hg19 4q12-31.21(chr4:52866944-143582507)x3 copy number gain not provided [RCV001827738] Chr4:52866944..143582507 [GRCh37]
Chr4:4q12-31.21
pathogenic
NM_145244.4(DDIT4L):c.310C>G (p.Arg104Gly) single nucleotide variant Inborn genetic diseases [RCV003276414] Chr4:100187949 [GRCh38]
Chr4:101109106 [GRCh37]
Chr4:4q24
uncertain significance
NM_145244.4(DDIT4L):c.73C>T (p.Pro25Ser) single nucleotide variant Inborn genetic diseases [RCV002688370] Chr4:100189911 [GRCh38]
Chr4:101111068 [GRCh37]
Chr4:4q24
uncertain significance
NM_145244.4(DDIT4L):c.530T>C (p.Val177Ala) single nucleotide variant Inborn genetic diseases [RCV002783252] Chr4:100187729 [GRCh38]
Chr4:101108886 [GRCh37]
Chr4:4q24
uncertain significance
NM_145244.4(DDIT4L):c.314G>T (p.Gly105Val) single nucleotide variant Inborn genetic diseases [RCV002889006] Chr4:100187945 [GRCh38]
Chr4:101109102 [GRCh37]
Chr4:4q24
uncertain significance
NM_145244.4(DDIT4L):c.209A>T (p.Gln70Leu) single nucleotide variant Inborn genetic diseases [RCV002782139] Chr4:100188050 [GRCh38]
Chr4:101109207 [GRCh37]
Chr4:4q24
uncertain significance
NM_145244.4(DDIT4L):c.371T>C (p.Ile124Thr) single nucleotide variant Inborn genetic diseases [RCV002802757] Chr4:100187888 [GRCh38]
Chr4:101109045 [GRCh37]
Chr4:4q24
uncertain significance
NM_145244.4(DDIT4L):c.137A>G (p.Glu46Gly) single nucleotide variant Inborn genetic diseases [RCV003300927] Chr4:100188122 [GRCh38]
Chr4:101109279 [GRCh37]
Chr4:4q24
uncertain significance
GRCh37/hg19 4q23-24(chr4:100542119-103793167)x1 copy number loss not provided [RCV003485432] Chr4:100542119..103793167 [GRCh37]
Chr4:4q23-24
pathogenic
GRCh37/hg19 4q23-24(chr4:100980656-101197518)x3 copy number gain not provided [RCV003484195] Chr4:100980656..101197518 [GRCh37]
Chr4:4q23-24
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:791
Count of miRNA genes:579
Interacting mature miRNAs:648
Transcripts:ENST00000273990, ENST00000502763, ENST00000513992
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-50253  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374101,108,171 - 101,108,269UniSTSGRCh37
Build 364101,327,194 - 101,327,292RGDNCBI36
Celera498,406,196 - 98,406,294RGD
Cytogenetic Map4q24UniSTS
HuRef496,846,408 - 96,846,506UniSTS
TNG Radiation Hybrid Map462026.0UniSTS
SHGC-8633  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374101,107,765 - 101,107,913UniSTSGRCh37
Build 364101,326,788 - 101,326,936RGDNCBI36
Celera498,405,790 - 98,405,938RGD
Cytogenetic Map4q24UniSTS
HuRef496,846,002 - 96,846,150UniSTS
TNG Radiation Hybrid Map462041.0UniSTS
D4S2493E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374101,108,313 - 101,108,395UniSTSGRCh37
Build 364101,327,336 - 101,327,418RGDNCBI36
Celera498,406,338 - 98,406,420RGD
Cytogenetic Map4q24UniSTS
HuRef496,846,550 - 96,846,632UniSTS
Stanford-G3 RH Map45644.0UniSTS
GeneMap99-G3 RH Map45572.0UniSTS
SHGC-24757  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374101,107,062 - 101,107,190UniSTSGRCh37
Build 364101,326,085 - 101,326,213RGDNCBI36
Celera498,405,087 - 98,405,215RGD
Cytogenetic Map4q24UniSTS
HuRef496,845,299 - 96,845,427UniSTS
TNG Radiation Hybrid Map462071.0UniSTS
GeneMap99-GB4 RH Map4494.64UniSTS
Whitehead-RH Map4527.9UniSTS
GeneMap99-G3 RH Map45572.0UniSTS
Ddit4l  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374101,108,981 - 101,109,057UniSTSGRCh37
Celera498,407,006 - 98,407,082UniSTS
HuRef496,847,217 - 96,847,293UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 2 2 2
Medium 47 56 13 94 16 1 998 824 373 114 128 33 95 48 858
Low 1811 1880 1208 141 565 74 3089 1037 3272 258 1253 1333 74 1 1155 1845 5 2
Below cutoff 490 968 459 349 1046 350 238 319 61 29 48 203 3 1 82 1

Sequence


RefSeq Acc Id: ENST00000273990   ⟹   ENSP00000354830
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4100,185,870 - 100,190,468 (-)Ensembl
RefSeq Acc Id: ENST00000502763   ⟹   ENSP00000427301
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4100,187,728 - 100,190,304 (-)Ensembl
RefSeq Acc Id: ENST00000513992   ⟹   ENSP00000427040
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4100,187,875 - 100,190,782 (-)Ensembl
RefSeq Acc Id: NM_145244   ⟹   NP_660287
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384100,185,870 - 100,190,468 (-)NCBI
GRCh374101,106,267 - 101,111,939 (-)NCBI
Build 364101,326,050 - 101,330,636 (-)NCBI Archive
Celera498,405,052 - 98,409,638 (-)RGD
HuRef496,845,264 - 96,850,266 (-)ENTREZGENE
CHM1_14101,083,602 - 101,088,230 (-)NCBI
T2T-CHM13v2.04103,501,503 - 103,506,101 (-)NCBI
Sequence:
RefSeq Acc Id: NP_660287   ⟸   NM_145244
- UniProtKB: B2R7C3 (UniProtKB/Swiss-Prot),   Q96D03 (UniProtKB/Swiss-Prot),   D6RJ99 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000427301   ⟸   ENST00000502763
RefSeq Acc Id: ENSP00000354830   ⟸   ENST00000273990
RefSeq Acc Id: ENSP00000427040   ⟸   ENST00000513992

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q96D03-F1-model_v2 AlphaFold Q96D03 1-193 view protein structure

Promoters
RGD ID:6868130
Promoter ID:EPDNEW_H7230
Type:initiation region
Name:DDIT4L_1
Description:DNA damage inducible transcript 4 like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh384100,190,468 - 100,190,528EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:30555 AgrOrtholog
COSMIC DDIT4L COSMIC
Ensembl Genes ENSG00000145358 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000273990 ENTREZGENE
  ENST00000273990.6 UniProtKB/Swiss-Prot
  ENST00000502763.1 UniProtKB/TrEMBL
  ENST00000513992.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.470.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000145358 GTEx
HGNC ID HGNC:30555 ENTREZGENE
Human Proteome Map DDIT4L Human Proteome Map
InterPro RTP801-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RTP801-like_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:115265 UniProtKB/Swiss-Prot
NCBI Gene 115265 ENTREZGENE
OMIM 607730 OMIM
PANTHER DNA DAMAGE-INDUCIBLE TRANSCRIPT 4-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12478 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RTP801_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA128394749 PharmGKB
UniProt B2R7C3 ENTREZGENE
  D6RD49_HUMAN UniProtKB/TrEMBL
  D6RJ99 ENTREZGENE, UniProtKB/TrEMBL
  DDT4L_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B2R7C3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 DDIT4L  DNA damage inducible transcript 4 like    DNA-damage-inducible transcript 4-like  Symbol and/or name change 5135510 APPROVED