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Gene: PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3) Homo sapiens
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Symbol: PIK3C3
Name: phosphatidylinositol 3-kinase catalytic subunit type 3
Description: Exhibits 1-phosphatidylinositol-3-kinase activity. Involved in several processes, including early endosome to late endosome transport; protein lipidation; and regulation of cytokinesis. Localizes to autolysosome; late endosome; and midbody; PARTICIPATES IN inositol metabolic pathway; phosphoinositide metabolic pathway; autophagy pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-hydroxypropanoic acid; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hVps34; MGC61518; phosphatidylinositol 3-kinase; phosphatidylinositol 3-kinase p100 subunit; phosphatidylinositol 3-kinase, catalytic subunit type 3; phosphoinositide-3-kinase, class 3; PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; VPS34
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1841,955,234 - 42,087,830 (+)EnsemblGRCh38hg38GRCh38
GRCh381841,955,226 - 42,087,830 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371839,535,165 - 39,662,272 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361837,789,197 - 37,915,446 (+)NCBINCBI36hg18NCBI36
Build 341837,789,196 - 37,915,442NCBI
Celera1836,343,751 - 36,469,999 (+)NCBI
Cytogenetic Map18q12.3NCBI
HuRef1836,394,067 - 36,520,574 (+)NCBIHuRef
CHM1_11839,462,179 - 39,588,448 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PIK3C3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732994
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.