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Gene: SOX8 (SRY-box transcription factor 8) Homo sapiens
Symbol: SOX8
Name: SRY-box transcription factor 8
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II core promoter sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to the nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC24837; SRY (sex determining region Y)-box 8; SRY box 8; SRY-box 8; transcription factor SOX-8
Mus musculus (house mouse) : Sox8 (SRY (sex determining region Y)-box 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sox8 (SRY-box transcription factor 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox8 (SRY-box transcription factor 8)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX8 (SRY-box transcription factor 8)
Canis lupus familiaris (dog) : SOX8 (SRY-box transcription factor 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox8 (SRY-box transcription factor 8)
Sus scrofa (pig) : SOX8 (SRY-box transcription factor 8)
Chlorocebus sabaeus (African green monkey) : SOX8 (SRY-box transcription factor 8)
Heterocephalus glaber (naked mole-rat) : Sox8 (SRY-box transcription factor 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl16981,770 - 986,979 (+)Ensembl
GRCh3816981,770 - 986,979 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37161,031,808 - 1,036,979 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616971,809 - 976,980 (+)NCBINCBI36hg18NCBI36
Build 3416971,808 - 976,979NCBI
Celera161,240,025 - 1,245,196 (+)NCBI
Cytogenetic Map16p13.3NCBI
HuRef16957,907 - 962,880 (+)NCBIHuRef
CHM1_1161,030,757 - 1,035,928 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SOX8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319208
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.