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Gene: ANK1 (ankyrin 1) Homo sapiens
Symbol: ANK1
Name: ankyrin 1
Description: Exhibits cytoskeletal protein binding activity and enzyme binding activity. Involved in endoplasmic reticulum to Golgi vesicle-mediated transport and protein localization to plasma membrane. Localizes to the cytoplasmic side of plasma membrane and spectrin-associated cytoskeleton. Implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ANK; ANK-1; ankyrin 1, erythrocytic; ankyrin-1; ankyrin-R; erythrocyte ankyrin; SPH1; SPH2
Mus musculus (house mouse) : Ank1 (ankyrin 1, erythroid)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ank1 (ankyrin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ank1 (ankyrin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ANK1 (ankyrin 1)
Canis lupus familiaris (dog) : ANK1 (ankyrin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ank1 (ankyrin 1)
Sus scrofa (pig) : ANK1 (ankyrin 1)
Chlorocebus sabaeus (green monkey) : ANK1 (ankyrin 1)
Heterocephalus glaber (naked mole-rat) : Ank1 (ankyrin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl841,653,220 - 41,896,762 (-)Ensembl
GRCh38841,653,225 - 41,896,741 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37841,510,744 - 41,754,280 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36841,629,901 - 41,774,297 (-)NCBINCBI36hg18NCBI36
Build 34841,632,000 - 41,641,949NCBI
Celera840,459,268 - 40,702,528 (-)NCBI
Cytogenetic Map8p11.21NCBI
HuRef840,038,471 - 40,281,660 (-)NCBIHuRef
CHM1_1841,558,937 - 41,802,421 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

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