Gene: KCNB1 (potassium voltage-gated channel subfamily B member 1) Homo sapiens
Symbol: KCNB1
Name: potassium voltage-gated channel subfamily B member 1
Description: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: delayed rectifier potassium channel 1; delayed rectifier potassium channel Kv2.1; DRK1; EIEE26; h-DRK1; h-DRK1 K(+) channel; KV2.1; OTTHUMP00000031697; potassium channel protein DRK1; potassium channel, voltage gated Shab related subfamily B, member 1; potassium voltage-gated channel, Shab-related subfamily, member 1; voltage-gated potassium channel subunit Kv2.1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382049,363,877 - 49,484,033 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372047,988,505 - 48,099,181 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362047,421,912 - 47,532,588 (-)NCBINCBI36hg18NCBI36
Build 342047,421,911 - 47,532,588NCBI
Celera2044,693,122 - 44,803,814 (-)NCBI
Cytogenetic Map20q13.13NCBI
HuRef2044,737,067 - 44,847,754 (-)NCBIHuRef
CHM1_12047,884,803 - 48,003,606 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

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Comparative Map Data
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miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCNB1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732211
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-02-19
Status: ACTIVE