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Gene: Kcnb1 (potassium voltage gated channel, Shab-related subfamily, member 1) Mus musculus
Symbol: Kcnb1
Name: potassium voltage gated channel, Shab-related subfamily, member 1
Description: Exhibits delayed rectifier potassium channel activity. Involved in several processes, including cellular response to glucose stimulus; negative regulation of insulin secretion; and positive regulation of long-term synaptic depression. Localizes to dendrite; neuronal cell body membrane; and voltage-gated potassium channel complex. Is expressed in brain; heart; heart ventricle; and hindlimb muscle. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 26. Orthologous to human KCNB1 (potassium voltage-gated channel subfamily B member 1); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; 3,4-methylenedioxymethamphetamine; amiodarone.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Kcr1-1; Kv2.1; mShab; potassium voltage-gated channel subfamily B member 1; Shab; voltage-gated potassium channel subunit Kv2.1
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl2167,095,969 - 167,190,155 (-)EnsemblGRCm38mm10GRCm38
GRCm382167,095,969 - 167,190,072 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372166,928,878 - 167,014,299 (-)NCBIGRCm37mm9NCBIm37
MGSCv362166,794,583 - 166,880,004 (-)NCBImm8
Celera2173,043,474 - 173,128,977 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map287.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kcnb1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732212
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.