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Gene: ROBO3 (roundabout guidance receptor 3) Homo sapiens
Symbol: ROBO3
Name: roundabout guidance receptor 3
Description: Predicted to have cell-cell adhesion mediator activity. Predicted to be involved in axon midline choice point recognition; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to localize to axon and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ21044; HGPPS; HGPPS1; HGPS; horizontal gaze palsy with progressive scoliosis; RBIG1; retinoblastoma inhibiting gene 1; RIG1; roundabout homolog 3; roundabout, axon guidance receptor, homolog 3; roundabout-like protein 3
Mus musculus (house mouse) : Robo3 (roundabout guidance receptor 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Robo3 (roundabout guidance receptor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Robo3 (roundabout guidance receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ROBO3 (roundabout guidance receptor 3)
Canis lupus familiaris (dog) : ROBO3 (roundabout guidance receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Robo3 (roundabout guidance receptor 3)
Sus scrofa (pig) : ROBO3 (roundabout guidance receptor 3)
Chlorocebus sabaeus (African green monkey) : ROBO3 (roundabout guidance receptor 3)
Heterocephalus glaber (naked mole-rat) : Robo3 (roundabout guidance receptor 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl11124,865,432 - 124,881,471 (+)EnsemblGRCh38hg38GRCh38
GRCh3811124,865,432 - 124,881,471 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711124,735,305 - 124,751,370 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,240,492 - 124,256,572 (+)NCBINCBI36hg18NCBI36
Celera11121,895,484 - 121,911,549 (+)NCBI
Cytogenetic Map11q24.2NCBI
HuRef11120,677,663 - 120,693,728 (+)NCBIHuRef
CHM1_111124,621,414 - 124,637,480 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ROBO3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1322248
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.