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Gene: CXCL5 (C-X-C motif chemokine ligand 5) Homo sapiens
Symbol: CXCL5
Name: C-X-C motif chemokine ligand 5
Description: Exhibits identical protein binding activity. Predicted to be involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; cellular response to lipopolysaccharide; and neutrophil chemotaxis. Predicted to localize to the extracellular space. Implicated in idiopathic pulmonary fibrosis. Biomarker of several diseases, including common cold; diffuse scleroderma; hyperhomocysteinemia; lung disease (multiple); and sinusitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C-X-C motif chemokine 5; chemokine (C-X-C motif) ligand 5; ENA-78; ENA-78(1-78); epithelial-derived neutrophil activating protein 78; epithelial-derived neutrophil-activating peptide 78; epithelial-derived neutrophil-activating protein 78; neutrophil-activating peptide ENA-78; neutrophil-activating protein 78; SCYB5; small inducible cytokine B5; small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78); small-inducible cytokine B5
Pan paniscus (bonobo/pygmy chimpanzee) : CXCL5 (C-X-C motif chemokine ligand 5)
Canis lupus familiaris (dog) : LOC106557449 (alveolar macrophage chemotactic factor-like)
Chlorocebus sabaeus (African green monkey) : CXCL5 (C-X-C motif chemokine ligand 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl473,995,642 - 73,998,677 (-)EnsemblGRCh38hg38GRCh38
GRCh38473,995,642 - 73,998,677 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37474,861,359 - 74,864,446 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36475,080,223 - 75,083,280 (-)NCBINCBI36hg18NCBI36
Build 34475,226,394 - 75,229,451NCBI
Celera472,221,508 - 72,224,565 (-)NCBI
Cytogenetic Map4q13.3NCBI
HuRef470,672,284 - 70,675,371 (-)NCBIHuRef
CHM1_1474,897,244 - 74,900,331 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CXCL5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348297
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.