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Gene: PKNOX2 (PBX/knotted 1 homeobox 2) Homo sapiens
Symbol: PKNOX2
Name: PBX/knotted 1 homeobox 2
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Localizes to intercellular bridge and nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ13074; homeobox protein PKNOX2; homeobox protein PREP-2; PBX/knotted homeobox 2; PREP2
Mus musculus (house mouse) : Pknox2 (Pbx/knotted 1 homeobox 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pknox2 (PBX/knotted 1 homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pknox2 (PBX/knotted 1 homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PKNOX2 (PBX/knotted 1 homeobox 2)
Canis lupus familiaris (dog) : PKNOX2 (PBX/knotted 1 homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pknox2 (PBX/knotted 1 homeobox 2)
Sus scrofa (pig) : PKNOX2 (PBX/knotted 1 homeobox 2)
Chlorocebus sabaeus (African green monkey) : PKNOX2 (PBX/knotted 1 homeobox 2)
Heterocephalus glaber (naked mole-rat) : Pknox2 (PBX/knotted 1 homeobox 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Annotation category: partial on reference assembly
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl11125,164,687 - 125,433,389 (+)EnsemblGRCh38hg38GRCh38
GRCh3811125,164,751 - 125,433,389 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711125,034,559 - 125,303,285 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,539,769 - 124,808,495 (+)NCBINCBI36hg18NCBI36
Build 3411124,726,419 - 124,808,264NCBI
Celera11122,194,601 - 122,463,611 (+)NCBI
Cytogenetic Map11q24.2NCBI
HuRef11120,976,463 - 121,244,840 (+)NCBIHuRef
CHM1_111124,920,619 - 125,189,521 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PKNOX2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348448
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.