Pknox2 (PBX/knotted 1 homeobox 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Pknox2 (PBX/knotted 1 homeobox 2) Chinchilla lanigera
Analyze
Symbol: Pknox2
Name: PBX/knotted 1 homeobox 2
RGD ID: 8737693
Description: ENCODES a protein that exhibits actin filament binding (ortholog); actin monomer binding (ortholog); DNA binding (ortholog); INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog); Familial Prostate Cancer (ortholog); FOUND IN actin cytoskeleton (ortholog); cytoplasm (ortholog); intercellular bridge (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox protein PKNOX2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541226,372,846 - 26,468,926 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541226,214,671 - 26,468,737 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Pknox2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541226,372,846 - 26,468,926 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541226,214,671 - 26,468,737 (+)NCBIChiLan1.0ChiLan1.0
PKNOX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811125,164,751 - 125,433,389 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11125,164,687 - 125,433,389 (+)EnsemblGRCh38hg38GRCh38
GRCh3711125,034,647 - 125,303,285 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,539,769 - 124,808,495 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411124,726,419 - 124,808,264NCBI
Celera11122,194,601 - 122,463,611 (+)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11120,976,463 - 121,244,840 (+)NCBIHuRef
CHM1_111124,920,619 - 125,189,521 (+)NCBICHM1_1
T2T-CHM13v2.011125,193,419 - 125,462,086 (+)NCBIT2T-CHM13v2.0
Pknox2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39936,802,278 - 37,058,637 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl936,802,278 - 37,058,703 (-)EnsemblGRCm39 Ensembl
GRCm38936,890,979 - 37,147,342 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl936,890,982 - 37,147,407 (-)EnsemblGRCm38mm10GRCm38
MGSCv37936,698,567 - 36,954,899 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36936,640,653 - 36,896,985 (-)NCBIMGSCv36mm8
Celera934,095,372 - 34,359,379 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map920.7NCBI
Pknox2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8844,789,464 - 45,051,933 (-)NCBIGRCr8
mRatBN7.2836,600,633 - 36,863,131 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl836,600,636 - 36,790,940 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx840,610,916 - 40,800,359 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0838,893,988 - 39,083,446 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0836,756,879 - 36,946,335 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0839,361,698 - 39,551,700 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,361,218 - 39,551,700 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,364,740 - 39,554,742 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4838,136,835 - 38,325,406 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera837,651,569 - 37,840,535 (+)NCBICelera
Cytogenetic Map8q22NCBI
PKNOX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29125,807,624 - 126,128,241 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111126,912,553 - 127,240,365 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011119,991,916 - 120,259,800 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111123,906,012 - 124,173,865 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11124,072,715 - 124,173,865 (+)Ensemblpanpan1.1panPan2
PKNOX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.159,054,138 - 9,363,750 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl59,056,134 - 9,178,159 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha59,098,622 - 9,408,616 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.058,994,772 - 9,302,925 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl58,994,772 - 9,251,650 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.159,065,978 - 9,375,742 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.059,036,663 - 9,346,271 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.059,072,792 - 9,382,834 (-)NCBIUU_Cfam_GSD_1.0
Pknox2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947107,342,759 - 107,612,737 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367431,661,791 - 1,858,278 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367431,661,783 - 1,860,299 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PKNOX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl952,349,714 - 52,610,680 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1952,303,022 - 52,608,505 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2958,127,081 - 58,195,478 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PKNOX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11116,332,851 - 116,604,758 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1116,523,593 - 116,605,161 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660439,519,677 - 9,788,985 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pknox2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249271,275,956 - 1,460,170 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249271,197,610 - 1,459,777 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000021387   ⟹   ENSCLAP00000021186
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541226,372,846 - 26,468,926 (+)Ensembl
RefSeq Acc Id: XM_005378457   ⟹   XP_005378514
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541226,214,671 - 26,468,737 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005378458   ⟹   XP_005378515
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541226,214,671 - 26,468,737 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013511208   ⟹   XP_013366662
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541226,236,993 - 26,468,737 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013511209   ⟹   XP_013366663
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541226,390,476 - 26,468,737 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005378514 (Get FASTA)   NCBI Sequence Viewer  
  XP_005378515 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366662 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366663 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000021186
  ENSCLAP00000021186.1
RefSeq Acc Id: XP_005378514   ⟸   XM_005378457
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YT17 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005378515   ⟸   XM_005378458
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YT17 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366662   ⟸   XM_013511208
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YT17 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366663   ⟸   XM_013511209
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000021186   ⟸   ENSCLAT00000021387
Protein Domains
Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014511 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000021387 ENTREZGENE
  ENSCLAT00000021387.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_KN_domain UniProtKB/TrEMBL
  PKNOX/Meis_N UniProtKB/TrEMBL
NCBI Gene Pknox2 ENTREZGENE
PANTHER HOMEOBOX PROTEIN PKNOX2 UniProtKB/TrEMBL
  HOMEOBOX PROTEIN TRANSCRIPTION FACTORS UniProtKB/TrEMBL
Pfam Homeobox_KN UniProtKB/TrEMBL
  Meis_PKNOX_N UniProtKB/TrEMBL
PROSITE HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A8C2YT17 ENTREZGENE, UniProtKB/TrEMBL