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Gene: SLCO1B3 (solute carrier organic anion transporter family member 1B3) Homo sapiens
Symbol: SLCO1B3
Name: solute carrier organic anion transporter family member 1B3
Description: Predicted to have bile acid transmembrane transporter activity and sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in bile acid and bile salt transport and sodium-independent organic anion transport. Localizes to the plasma membrane. Implicated in bilirubin metabolic disorder.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HBLRR; liver-specific organic anion transporter 2; liver-specific organic anion transporter 3TM13; LST-2; LST-3TM13; LST3; OATP-8; OATP1B3; OATP8; organic anion transporter 8; organic anion transporter LST-3c; organic anion-transporting polypeptide 8; SLC21A8; solute carrier family 21 (organic anion transporter), member 8; solute carrier family 21 member 8; solute carrier organic anion transporter family, member 1B3
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1220,810,702 - 20,916,911 (+)EnsemblGRCh38hg38GRCh38
GRCh381220,810,705 - 20,916,911 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371220,963,638 - 21,070,019 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361220,854,905 - 20,960,925 (+)NCBINCBI36hg18NCBI36
Build 341220,859,894 - 20,960,921NCBI
Celera1226,119,013 - 26,224,987 (+)NCBI
Cytogenetic Map12p12.2NCBI
HuRef1220,736,680 - 20,842,844 (+)NCBIHuRef
CHM1_11220,929,128 - 21,035,317 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SLCO1B3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350750
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.