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Gene: TELO2 (telomere maintenance 2) Homo sapiens
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Symbol: TELO2
Name: telomere maintenance 2
Description: Exhibits Hsp90 protein binding activity and protein kinase binding activity. Involved in positive regulation of TOR signaling; positive regulation of protein serine/threonine kinase activity; and protein stabilization. Localizes to several cellular components, including the TORC1 complex; TORC2 complex; and nuclear lumen.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CLK2; DKFZp434A073; FLJ10924; KIAA0683; protein clk-2 homolog; TEL2; TEL2, telomere maintenance 2, homolog; telomere length regulation protein TEL2 homolog; YHFS
Orthologs:
Mus musculus (house mouse) : Telo2 (telomere maintenance 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Telo2 (telomere maintenance 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Telo2 (telomere maintenance 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TELO2 (telomere maintenance 2)
Canis lupus familiaris (dog) : TELO2 (telomere maintenance 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Telo2 (telomere maintenance 2)
Sus scrofa (pig) : TELO2 (telomere maintenance 2)
Chlorocebus sabaeus (green monkey) : TELO2 (telomere maintenance 2)
Heterocephalus glaber (naked mole-rat) : Telo2 (telomere maintenance 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl161,493,344 - 1,510,457 (+)Ensembl
GRCh38161,493,345 - 1,510,459 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37161,543,352 - 1,560,460 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,483,423 - 1,500,456 (+)NCBINCBI36hg18NCBI36
Celera161,755,633 - 1,772,735 (+)NCBI
Cytogenetic Map16p13.3NCBI
HuRef161,469,280 - 1,486,045 (+)NCBIHuRef
CHM1_1161,543,348 - 1,560,420 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TELO2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605097
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.