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Gene: SCUBE1 (signal peptide, CUB domain and EGF like domain containing 1) Homo sapiens
Symbol: SCUBE1
Name: signal peptide, CUB domain and EGF like domain containing 1
Description: This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-like repeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells and may play an important role in vascular biology. [provided by RefSeq, Oct 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: signal peptide, CUB and EGF-like domain-containing protein 1; signal peptide, CUB domain, EGF-like 1; signal peptide-CUB domain-EGF-related 1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382243,203,223 - 43,343,388 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372243,599,229 - 43,739,394 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,929,174 - 42,069,299 (-)NCBINCBI36hg18NCBI36
Build 342241,924,495 - 42,063,785NCBI
Celera2227,509,622 - 27,649,802 (-)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2226,557,501 - 26,697,243 (-)NCBIHuRef
CHM1_12243,558,135 - 43,698,313 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SCUBE1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319121
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.