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Gene: DCX (doublecortin) Homo sapiens
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Symbol: DCX
Name: doublecortin
Description: Exhibits microtubule binding activity and protein kinase binding activity. Involved in neuron migration. Localizes to the neuron projection. Implicated in lissencephaly and subcortical band heterotopia. Biomarker of malignant glioma and temporal lobe epilepsy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DBCN; DC; doublecortex; doublin; FLJ51296; lis-X; lissencephalin-X; LISX; neuronal migration protein doublecortin; SCLH; XLIS
Orthologs:
Mus musculus (house mouse) : Dcx (doublecortin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dcx (doublecortin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dcx (doublecortin)
Pan paniscus (bonobo/pygmy chimpanzee) : DCX (doublecortin)
Canis lupus familiaris (dog) : DCX (doublecortin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dcx (doublecortin)
Sus scrofa (pig) : DCX (doublecortin)
Chlorocebus sabaeus (African green monkey) : DCX (doublecortin)
Heterocephalus glaber (naked mole-rat) : Dcx (doublecortin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX111,293,779 - 111,412,429 (-)Ensembl
GRCh38X111,293,779 - 111,412,205 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X110,537,007 - 110,655,460 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X110,423,663 - 110,542,062 (-)NCBINCBI36hg18NCBI36
Build 34X110,343,151 - 110,461,551NCBI
CeleraX111,016,623 - 111,134,992 (-)NCBI
Cytogenetic MapXq23NCBI
HuRefX100,159,414 - 100,278,099 (-)NCBIHuRef
CHM1_1X110,448,522 - 110,566,950 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on DCX
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348637
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.