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Gene: PPARD (peroxisome proliferator activated receptor delta) Homo sapiens
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Symbol: PPARD
Name: peroxisome proliferator activated receptor delta
RGD ID: 736289
Description: Exhibits several functions, including linoleic acid binding activity; nuclear receptor activity; and transcription coactivator binding activity. Involved in apoptotic signaling pathway and positive regulation of transcription, DNA-templated. Predicted to localize to RNA polymerase II transcription regulator complex and nuclear chromatin. Implicated in type 2 diabetes mellitus. Biomarker of biliary tract cancer and pancreatic cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FAAR; MGC3931; NR1C2; NUC1; NUCI; NUCII; nuclear hormone receptor 1; nuclear receptor subfamily 1 group C member 2; peroxisome proliferator-activated nuclear receptor beta/delta variant 2; peroxisome proliferator-activated receptor beta; peroxisome proliferator-activated receptor delta; PPAR-beta; PPAR-delta; PPARB; PPARD/MYO1D fusion
Orthologs:
Mus musculus (house mouse) : Ppard (peroxisome proliferator activator receptor delta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ppard (peroxisome proliferator-activated receptor delta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppard (peroxisome proliferator activated receptor delta)
Pan paniscus (bonobo/pygmy chimpanzee) : PPARD (peroxisome proliferator activated receptor delta)
Canis lupus familiaris (dog) : PPARD (peroxisome proliferator activated receptor delta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppard (peroxisome proliferator activated receptor delta)
Sus scrofa (pig) : PPARD (peroxisome proliferator activated receptor delta)
Chlorocebus sabaeus (African green monkey) : PPARD (peroxisome proliferator activated receptor delta)
Heterocephalus glaber (naked mole-rat) : Ppard (peroxisome proliferator activated receptor delta)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl635,342,558 - 35,428,191 (+)EnsemblGRCh38hg38GRCh38
GRCh38635,342,558 - 35,428,180 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37635,310,335 - 35,395,968 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36635,418,313 - 35,503,933 (+)NCBINCBI36hg18NCBI36
Build 34635,418,363 - 35,501,149NCBI
Celera636,864,336 - 36,949,951 (+)NCBI
Cytogenetic Map6p21.31NCBI
HuRef635,031,309 - 35,116,788 (+)NCBIHuRef
CHM1_1635,312,398 - 35,397,989 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PPARD
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736289
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.