CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: amphotericin B
Accession: CHEBI:2682
browse the term
Definition: A macrolide antibiotic used to treat potentially life-threatening fungal infections.
Synonyms: exact_synonym: (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
related_synonym: AMPH-B; Amphotericine B; Formula=C47H73NO17; InChI=1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1; InChIKey=APKFDSVGJQXUKY-INPOYWNPSA-N; Liposomal Amphotericin B; SMILES=[H][C@]12C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\\C=C\\C=C\\C=C\\C=C\\C=C\\C=C\\C=C\\[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(O)=O)O2; amfotericina B; amphotericinum B
alt_id: CHEBI:106303; CHEBI:566395
xref: Beilstein:4645978; CAS:1397-89-3; DrugBank:DB00681; Drug_Central:197; KEGG:C06573; KEGG:D00203; LIPID_MAPS_instance:LMPK06000002
xref_mesh: MESH:D000666
xref: PMID:11429202; PMID:11930683; PMID:15793154; PMID:16120633; PMID:16793999; PMID:1732516; PMID:17507115; PMID:33846129; Patent:US2908611; Reaxys:4645978; Wikipedia:Amphotericin_B
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Abca1
ATP binding cassette subfamily A member 1
multiple interactions
ISO
[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCA1 mRNA
CTD
PMID:36464106
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Abca12
ATP binding cassette subfamily A member 12
decreases expression
ISO
Amphotericin B analog results in decreased expression of ABCA12 mRNA
CTD
PMID:28534445
NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
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Abcb11
ATP binding cassette subfamily B member 11
multiple interactions
ISO
[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCB11 mRNA
CTD
PMID:36464106
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Abcb1a
ATP binding cassette subfamily B member 1A
multiple interactions
ISO
[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCB1A mRNA
CTD
PMID:36464106
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcc2
ATP binding cassette subfamily C member 2
multiple interactions
ISO
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA
CTD
PMID:36464106
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abcc3
ATP binding cassette subfamily C member 3
multiple interactions
ISO
[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC3 mRNA
CTD
PMID:36464106
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abcg1
ATP binding cassette subfamily G member 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of ABCG1 mRNA
CTD
PMID:28534445
NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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Abcg2
ATP binding cassette subfamily G member 2
multiple interactions
ISO
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA
CTD
PMID:36464106
NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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Abcg5
ATP binding cassette subfamily G member 5
multiple interactions
ISO
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA
CTD
PMID:36464106
NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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Acrv1
acrosomal vesicle protein 1
increases expression
ISO
Amphotericin B analog results in increased expression of ACRV1 mRNA
CTD
PMID:28534445
NCBI chr 8:36,404,394...36,409,971
Ensembl chr 8:36,404,394...36,424,959
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Adamts12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
increases expression
ISO
Amphotericin B analog results in increased expression of ADAMTS12 mRNA
CTD
PMID:28534445
NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629
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Adcy2
adenylate cyclase 2
increases expression
ISO
Amphotericin B analog results in increased expression of ADCY2 mRNA
CTD
PMID:28534445
NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236
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Adora3
adenosine A3 receptor
increases expression
ISO
Amphotericin B analog results in increased expression of ADORA3 mRNA
CTD
PMID:28534445
NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
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Adra2a
adrenoceptor alpha 2A
decreases expression
ISO
Amphotericin B analog results in decreased expression of ADRA2A mRNA
CTD
PMID:28534445
NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
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Aldh8a1
aldehyde dehydrogenase 8 family, member A1
decreases expression
ISO
Amphotericin B analog results in decreased expression of ALDH8A1 mRNA
CTD
PMID:28534445
NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
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Alk
ALK receptor tyrosine kinase
increases expression
ISO
Amphotericin B results in increased expression of ALK mRNA
CTD
PMID:28534445
NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
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Alox5
arachidonate 5-lipoxygenase
decreases expression
ISO
Amphotericin B analog results in decreased expression of ALOX5 mRNA
CTD
PMID:28534445
NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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Amacr
alpha-methylacyl-CoA racemase
decreases expression
ISO
Amphotericin B analog results in decreased expression of AMACR mRNA
CTD
PMID:28534445
NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
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Ank3
ankyrin 3
decreases expression
ISO
Amphotericin B analog results in decreased expression of ANK3 mRNA
CTD
PMID:28534445
NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
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Anxa9
annexin A9
decreases expression
ISO
Amphotericin B analog results in decreased expression of ANXA9 mRNA
CTD
PMID:28534445
NCBI chr 2:182,873,185...182,884,501
Ensembl chr 2:182,872,929...182,883,374
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Ap3b2
adaptor related protein complex 3 subunit beta 2
increases expression
ISO
Amphotericin B analog results in increased expression of AP3B2 mRNA
CTD
PMID:28534445
NCBI chr 1:135,412,580...135,445,191
Ensembl chr 1:135,412,580...135,445,191
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Apbb2
amyloid beta precursor protein binding family B member 2
increases expression
ISO
Amphotericin B analog results in increased expression of APBB2 mRNA
CTD
PMID:28534445
NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495
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Apoc2
apolipoprotein C2
increases expression
ISO
Amphotericin B analog results in increased expression of APOC2 mRNA
CTD
PMID:28534445
NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
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Aqp3
aquaporin 3 (Gill blood group)
decreases expression
ISO
Amphotericin B analog results in decreased expression of AQP3 mRNA
CTD
PMID:28534445
NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
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Aqp5
aquaporin 5
increases expression
ISO
Amphotericin B analog results in increased expression of AQP5 mRNA
CTD
PMID:28534445
NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209
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Arg2
arginase 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of ARG2 mRNA
CTD
PMID:28534445
NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
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Arhgef26
Rho guanine nucleotide exchange factor 26
increases expression
ISO
Amphotericin B results in increased expression of ARHGEF26 mRNA
CTD
PMID:20849824
NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819
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Arnt
aryl hydrocarbon receptor nuclear translocator
multiple interactions
ISO
Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]
CTD
PMID:16189267
NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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Arrb1
arrestin, beta 1
increases expression
ISO
Amphotericin B analog results in increased expression of ARRB1 mRNA
CTD
PMID:28534445
NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
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Atg3
autophagy related 3
decreases expression
ISO
Amphotericin B results in decreased expression of ATG3 mRNA
CTD
PMID:20849824
NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224
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Atp10b
ATPase phospholipid transporting 10B
increases expression
ISO
Amphotericin B analog results in increased expression of ATP10B mRNA
CTD
PMID:28534445
NCBI chr10:27,495,207...27,751,313
Ensembl chr10:27,408,747...27,749,637
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B3gnt4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
increases expression
ISO
Amphotericin B analog results in increased expression of B3GNT4 mRNA
CTD
PMID:28534445
NCBI chr12:33,070,221...33,073,904
Ensembl chr12:33,060,416...33,073,854
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Bag4
BAG cochaperone 4
decreases expression
ISO
Amphotericin B analog results in decreased expression of BAG4 mRNA
CTD
PMID:28534445
NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
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Bcl6
BCL6, transcription repressor
decreases expression
ISO
Amphotericin B analog results in decreased expression of BCL6 mRNA
CTD
PMID:28534445
NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
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Bend5
BEN domain containing 5
decreases expression
ISO
Amphotericin B analog results in decreased expression of BEND5 mRNA
CTD
PMID:28534445
NCBI chr 5:126,290,648...126,336,662
Ensembl chr 5:125,254,956...126,534,367
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Bmp2
bone morphogenetic protein 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of BMP2 mRNA; Amphotericin B results in decreased expression of BMP2 mRNA
CTD
PMID:28534445
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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Bmp7
bone morphogenetic protein 7
increases expression
ISO
Amphotericin B analog results in increased expression of BMP7 mRNA
CTD
PMID:28534445
NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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Bnc1
basonuclin zinc finger protein 1
increases expression
ISO
Amphotericin B analog results in increased expression of BNC1 mRNA
CTD
PMID:28534445
NCBI chr 1:135,917,676...135,943,333
Ensembl chr 1:135,917,687...135,943,333
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Bora
bora, aurora kinase A activator
decreases expression
ISO
Amphotericin B analog results in decreased expression of BORA mRNA
CTD
PMID:28534445
NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322
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Camk2g
calcium/calmodulin-dependent protein kinase II gamma
increases expression
ISO
Amphotericin B analog results in increased expression of CAMK2G mRNA
CTD
PMID:28534445
NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050
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Capn6
calpain 6
decreases expression
ISO
Amphotericin B analog results in decreased expression of CAPN6 mRNA
CTD
PMID:28534445
NCBI chr X:107,380,774...107,405,489
Ensembl chr X:107,380,774...107,405,489
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Car12
carbonic anhydrase 12
decreases expression
ISO
Amphotericin B analog results in decreased expression of CA12 mRNA
CTD
PMID:28534445
NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
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Car14
carbonic anhydrase 14
increases expression
ISO
Amphotericin B analog results in increased expression of CA14 mRNA
CTD
PMID:28534445
NCBI chr 2:183,442,263...183,449,231
Ensembl chr 2:183,441,667...183,449,693
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Car4
carbonic anhydrase 4
decreases expression
ISO
Amphotericin B analog results in decreased expression of CA4 mRNA
CTD
PMID:28534445
NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
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Car9
carbonic anhydrase 9
decreases expression
ISO
Amphotericin B analog results in decreased expression of CA9 mRNA
CTD
PMID:28534445
NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
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Carf
calcium responsive transcription factor
decreases expression
ISO
Amphotericin B analog results in decreased expression of CARF mRNA
CTD
PMID:28534445
NCBI chr 9:61,502,368...61,552,433
Ensembl chr 9:61,506,956...61,550,462
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Casp3
caspase 3
increases expression
ISO
Amphotericin B results in increased expression of CASP3 protein
CTD
PMID:23988732
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casq2
calsequestrin 2
increases expression
ISO
Amphotericin B analog results in increased expression of CASQ2 mRNA
CTD
PMID:28534445
NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267
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Cat
catalase
decreases expression
EXP
Amphotericin B results in decreased expression of CAT mRNA
CTD
PMID:20623750
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccl20
C-C motif chemokine ligand 20
increases expression
ISO
Amphotericin B analog results in increased expression of CCL20 mRNA; Amphotericin B results in increased expression of CCL20 mRNA
CTD
PMID:28534445
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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Ccne2
cyclin E2
decreases expression
ISO
Amphotericin B results in decreased expression of CCNE2 mRNA
CTD
PMID:28534445
NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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Ccr2
C-C motif chemokine receptor 2
decreases expression
EXP
Amphotericin B results in decreased expression of CCR2 mRNA
CTD
PMID:20623750
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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Cd14
CD14 molecule
decreases expression
ISO
Amphotericin B analog results in decreased expression of CD14 mRNA
CTD
PMID:28534445
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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Cd1d1
CD1d1 molecule
decreases expression
ISO
Amphotericin B analog results in decreased expression of CD1D mRNA
CTD
PMID:28534445
NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
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Cd2
Cd2 molecule
increases expression
ISO
Amphotericin B analog results in increased expression of CD2 mRNA
CTD
PMID:28534445
NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:188,710,900...188,724,026
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Cd3e
CD3 epsilon subunit of T-cell receptor complex
increases expression
ISO
Amphotericin B analog results in increased expression of CD3E mRNA
CTD
PMID:28534445
NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022
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Cd84
CD84 molecule
increases expression
ISO
Amphotericin B analog results in increased expression of CD84 mRNA
CTD
PMID:28534445
NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076
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Cdkl5
cyclin-dependent kinase-like 5
increases expression
ISO
Amphotericin B analog results in increased expression of CDKL5 mRNA
CTD
PMID:28534445
NCBI chr X:33,757,605...33,988,075
Ensembl chr X:33,821,257...33,986,582
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Cdsn
corneodesmosin
increases expression
ISO
Amphotericin B analog results in increased expression of CDSN mRNA
CTD
PMID:28534445
NCBI chr20:3,179,432...3,184,252
Ensembl chr20:3,179,438...3,184,250
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Ceacam15
CEA cell adhesion molecule 15
increases expression
ISO
Amphotericin B analog results in increased expression of CEACAM21 mRNA
CTD
PMID:28534445
NCBI chr 1:77,368,376...77,373,343
Ensembl chr 1:77,368,966...77,372,663
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Cep76
centrosomal protein 76
decreases expression
ISO
Amphotericin B analog results in decreased expression of CEP76 mRNA
CTD
PMID:28534445
NCBI chr18:61,174,514...61,208,512
Ensembl chr18:61,178,310...61,208,504
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Cga
glycoprotein hormones, alpha polypeptide
increases expression
ISO
Amphotericin B analog results in increased expression of CGA mRNA
CTD
PMID:28534445
NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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Chac1
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
increases expression
ISO
Amphotericin B analog results in increased expression of CHAC1 mRNA
CTD
PMID:28534445
NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
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Chi3l1
chitinase 3 like 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of CHI3L1 mRNA
CTD
PMID:28534445
NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
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Chl1
cell adhesion molecule L1-like
decreases expression
ISO
Amphotericin B analog results in decreased expression of CHL1 mRNA
CTD
PMID:28534445
NCBI chr 4:136,291,504...136,505,830
Ensembl chr 4:136,291,463...136,503,265
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Chp1
calcineurin-like EF-hand protein 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of CHP1 mRNA
CTD
PMID:28534445
NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
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Chrnb3
cholinergic receptor nicotinic beta 3 subunit
increases expression
ISO
Amphotericin B analog results in increased expression of CHRNB3 mRNA
CTD
PMID:28534445
NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360
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Clu
clusterin
affects expression decreases expression
EXP ISO
Amphotericin B affects the expression of CLU mRNA Amphotericin B analog results in decreased expression of CLU mRNA
CTD
PMID:20623750 PMID:28534445
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
decreases expression
ISO
Amphotericin B analog results in decreased expression of CMAHP mRNA
CTD
PMID:28534445
NCBI chr17:40,557,161...40,642,350
Ensembl chr17:40,583,667...40,642,275
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Cnr2
cannabinoid receptor 2
increases expression
ISO
Amphotericin B analog results in increased expression of CNR2 mRNA
CTD
PMID:28534445
NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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Cntn5
contactin 5
increases expression
ISO
Amphotericin B analog results in increased expression of CNTN5 mRNA
CTD
PMID:28534445
NCBI chr 8:6,735,715...7,967,727
Ensembl chr 8:6,738,239...7,967,957
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Col5a1
collagen type V alpha 1 chain
increases expression
ISO
Amphotericin B analog results in increased expression of COL5A1 mRNA
CTD
PMID:28534445
NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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Comt
catechol-O-methyltransferase
increases expression
ISO
Amphotericin B analog results in increased expression of COMT mRNA
CTD
PMID:28534445
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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Cpd
carboxypeptidase D
decreases expression
ISO
Amphotericin B analog results in decreased expression of CPD mRNA
CTD
PMID:28534445
NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491
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Cpt1b
carnitine palmitoyltransferase 1B
decreases expression
ISO
Amphotericin B analog results in decreased expression of CPT1B mRNA
CTD
PMID:28534445
NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
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Crispld2
cysteine-rich secretory protein LCCL domain containing 2
increases expression
ISO
Amphotericin B analog results in increased expression of CRISPLD2 mRNA
CTD
PMID:28534445
NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465
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Crybb1
crystallin, beta B1
increases expression
ISO
Amphotericin B analog results in increased expression of CRYBB1 mRNA
CTD
PMID:28534445
NCBI chr12:44,369,734...44,383,344
Ensembl chr12:44,369,735...44,383,344
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Csf2
colony stimulating factor 2
increases expression
ISO
Amphotericin B analog results in increased expression of CSF2 mRNA; Amphotericin B results in increased expression of CSF2 mRNA
CTD
PMID:28534445
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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Csgalnact2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
increases expression
ISO
Amphotericin B analog results in increased expression of CSGALNACT2 mRNA
CTD
PMID:28534445
NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839
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Cspg5
chondroitin sulfate proteoglycan 5
decreases expression
ISO
Amphotericin B analog results in decreased expression of CSPG5 mRNA
CTD
PMID:28534445
NCBI chr 8:110,220,506...110,234,766
Ensembl chr 8:110,220,653...110,234,758
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Cxcl1
C-X-C motif chemokine ligand 1
increases expression
ISO
Amphotericin B analog results in increased expression of CXCL1 mRNA
CTD
PMID:28534445
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
Amphotericin B analog results in increased expression of CXCL2 mRNA; Amphotericin B results in increased expression of CXCL2 mRNA
CTD
PMID:28534445
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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Cxcl3
C-X-C motif chemokine ligand 3
increases expression
ISO
Amphotericin B analog results in increased expression of CXCL1 mRNA
CTD
PMID:28534445
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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Cxcr4
C-X-C motif chemokine receptor 4
decreases expression
ISO
Amphotericin B analog results in decreased expression of CXCR4 mRNA
CTD
PMID:28534445
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
multiple interactions
ISO
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA
CTD
PMID:36464106
NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
increases expression
ISO
Amphotericin B analog results in increased expression of CYP2C19 mRNA
CTD
PMID:28534445
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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Cyp4b1
cytochrome P450, family 4, subfamily b, polypeptide 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of CYP4B1 mRNA
CTD
PMID:28534445
NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
multiple interactions
ISO
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA
CTD
PMID:36464106
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
G
Cyp7b1
cytochrome P450 family 7 subfamily B member 1
multiple interactions
ISO
[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7B1 mRNA
CTD
PMID:36464106
NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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Cyp8b1
cytochrome P450 family 8 subfamily B member 1
multiple interactions
ISO
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA
CTD
PMID:36464106
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
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Cyth4
cytohesin 4
increases expression
ISO
Amphotericin B analog results in increased expression of CYTH4 mRNA
CTD
PMID:28534445
NCBI chr 7:110,152,232...110,176,726
Ensembl chr 7:110,152,272...110,176,741
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Dclk1
doublecortin-like kinase 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of DCLK1 mRNA
CTD
PMID:28534445
NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956
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Dcstamp
dendrocyte expressed seven transmembrane protein
increases expression
ISO
Amphotericin B analog results in increased expression of DCSTAMP mRNA
CTD
PMID:28534445
NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
Amphotericin B results in increased expression of DDIT3 mRNA
CTD
PMID:28534445
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddx11
DEAD/H-box helicase 11
increases expression
ISO
Amphotericin B results in increased expression of DDX11 mRNA
CTD
PMID:28534445
NCBI chr 9:105,833,234...105,862,844
Ensembl chr 9:105,833,504...105,862,550
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Deptor
DEP domain containing MTOR-interacting protein
decreases expression
ISO
Amphotericin B analog results in decreased expression of DEPTOR mRNA
CTD
PMID:28534445
NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
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Dhrs7
dehydrogenase/reductase 7
decreases expression
ISO
Amphotericin B analog results in decreased expression of DHRS7 mRNA
CTD
PMID:28534445
NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892
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Dicer1
dicer 1 ribonuclease III
decreases expression
ISO
Amphotericin B analog results in decreased expression of DICER1 mRNA
CTD
PMID:28534445
NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
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Dkk4
dickkopf WNT signaling pathway inhibitor 4
increases expression
ISO
Amphotericin B analog results in increased expression of DKK4 mRNA
CTD
PMID:28534445
NCBI chr16:69,403,215...69,406,580
Ensembl chr16:69,402,989...69,406,580
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Dlgap1
DLG associated protein 1
decreases expression increases expression
ISO
Amphotericin B analog results in decreased expression of DLGAP1 mRNA Amphotericin B analog results in increased expression of DLGAP1 mRNA
CTD
PMID:28534445
NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817
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Dnah3
dynein, axonemal, heavy chain 3
increases expression
ISO
Amphotericin B analog results in increased expression of DNAH3 mRNA
CTD
PMID:28534445
NCBI chr 1:174,305,929...174,479,490
Ensembl chr 1:174,306,644...174,479,474
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Dnaja4
DnaJ heat shock protein family (Hsp40) member A4
increases expression
ISO
Amphotericin B analog results in increased expression of DNAJA4 mRNA
CTD
PMID:28534445
NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
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Dtx4
deltex E3 ubiquitin ligase 4
decreases expression
ISO
Amphotericin B analog results in decreased expression of DTX4 mRNA
CTD
PMID:28534445
NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818
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Duox2
dual oxidase 2
increases expression
ISO
Amphotericin B analog results in increased expression of DUOX2 mRNA
CTD
PMID:28534445
NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
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Dzip3
DAZ interacting zinc finger protein 3
decreases expression
ISO
Amphotericin B analog results in decreased expression of DZIP3 mRNA
CTD
PMID:28534445
NCBI chr11:51,823,235...51,893,353
Ensembl chr11:51,823,231...51,893,353
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E2f2
E2F transcription factor 2
increases expression
ISO
Amphotericin B analog results in increased expression of E2F2 mRNA
CTD
PMID:28534445
NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
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Ednrb
endothelin receptor type B
increases expression
ISO
Amphotericin B results in increased expression of EDNRB mRNA
CTD
PMID:20849824
NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
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Efr3b
EFR3 homolog B
increases expression
ISO
Amphotericin B analog results in increased expression of EFR3B mRNA
CTD
PMID:28534445
NCBI chr 6:26,947,436...27,021,113
Ensembl chr 6:26,948,540...27,020,933
G
Egln3
egl-9 family hypoxia-inducible factor 3
decreases expression
ISO
Amphotericin B analog results in decreased expression of EGLN3 mRNA
CTD
PMID:28534445
NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
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Emx2
empty spiracles homeobox 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of EMX2 mRNA
CTD
PMID:28534445
NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594
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Eno1
enolase 1
multiple interactions
ISO
Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of ENO1 mRNA]; Amphotericin B results in increased expression of and results in increased secretion of ENO1 protein
CTD
PMID:16189267 PMID:26259607
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
G
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of ENPP2 mRNA
CTD
PMID:28534445
NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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Ep300
E1A binding protein p300
multiple interactions
ISO
Amphotericin B inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]
CTD
PMID:16189267
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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Epo
erythropoietin
multiple interactions decreases expression
ISO EXP
Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]; Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA] Amphotericin B results in decreased expression of EPO protein
CTD
PMID:697352 PMID:2299214 PMID:16189267
NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
G
Epor
erythropoietin receptor
increases expression
ISO
Amphotericin B analog results in increased expression of EPOR mRNA; Amphotericin B results in increased expression of EPOR mRNA
CTD
PMID:28534445
NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
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Ereg
epiregulin
increases expression
ISO
Amphotericin B analog results in increased expression of EREG mRNA
CTD
PMID:28534445
NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
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Fam13a
family with sequence similarity 13, member A
decreases expression
ISO
Amphotericin B analog results in decreased expression of FAM13A mRNA
CTD
PMID:28534445
NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860
G
Fasn
fatty acid synthase
multiple interactions
ISO
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA
CTD
PMID:36464106
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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Fbln1
fibulin 1
increases expression
ISO
Amphotericin B analog results in increased expression of FBLN1 mRNA
CTD
PMID:28534445
NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
G
Fcgr1a
Fc gamma receptor 1A
increases expression
ISO
Amphotericin B analog results in increased expression of FCGR1A mRNA
CTD
PMID:28534445
NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
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Fgb
fibrinogen beta chain
decreases expression
ISO
Amphotericin B analog results in decreased expression of FGB mRNA
CTD
PMID:28534445
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
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Fgf4
fibroblast growth factor 4
increases expression
ISO
Amphotericin B analog results in increased expression of FGF4 mRNA
CTD
PMID:28534445
NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466
G
Fkbp5
FKBP prolyl isomerase 5
decreases expression
ISO
Amphotericin B analog results in decreased expression of FKBP5 mRNA
CTD
PMID:28534445
NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
G
Flrt3
fibronectin leucine rich transmembrane protein 3
decreases expression
ISO
Amphotericin B analog results in decreased expression of FLRT3 mRNA; Amphotericin B results in decreased expression of FLRT3 mRNA
CTD
PMID:28534445
NCBI chr 3:127,994,491...128,008,137
Ensembl chr 3:127,994,226...128,007,841
G
Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Amphotericin B analog results in increased expression of FOSB mRNA
CTD
PMID:28534445
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
G
Frmd4b
FERM domain containing 4B
decreases expression
ISO
Amphotericin B analog results in decreased expression of FRMD4B mRNA
CTD
PMID:28534445
NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197
G
Fsbp
fibrinogen silencer binding protein
decreases expression
ISO
Amphotericin B analog results in decreased expression of FSBP mRNA
CTD
PMID:28534445
NCBI chr 5:25,058,003...25,064,276
Ensembl chr 5:25,032,066...25,104,616
G
Fubp1
far upstream element binding protein 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of FUBP1 mRNA
CTD
PMID:28534445
NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
G
Fxr1
FMR1 autosomal homolog 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of FXR1 mRNA
CTD
PMID:28534445
NCBI chr 2:116,884,167...116,937,590
Ensembl chr 2:116,884,248...116,937,590
G
Fxyd3
FXYD domain-containing ion transport regulator 3
increases expression
ISO
Amphotericin B analog results in increased expression of FXYD3 mRNA
CTD
PMID:28534445
NCBI chr 1:86,305,531...86,312,455
G
Gal3st1
galactose-3-O-sulfotransferase 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of GAL3ST1 mRNA
CTD
PMID:28534445
NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388
G
Galr3
galanin receptor 3
increases expression
ISO
Amphotericin B analog results in increased expression of GALR3 mRNA
CTD
PMID:28534445
NCBI chr 7:110,603,525...110,608,429
Ensembl chr 7:110,605,226...110,607,685
G
Gdf15
growth differentiation factor 15
increases expression
ISO
Amphotericin B analog results in increased expression of GDF15 mRNA; Amphotericin B results in increased expression of GDF15 mRNA
CTD
PMID:28534445
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
G
Gfra3
GDNF family receptor alpha 3
increases expression
ISO
Amphotericin B analog results in increased expression of GFRA3 mRNA
CTD
PMID:28534445
NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105
G
Gfra4
GDNF family receptor alpha 4
increases expression
ISO
Amphotericin B analog results in increased expression of GFRA4 mRNA
CTD
PMID:28534445
NCBI chr 3:118,254,937...118,262,252
Ensembl chr 3:118,255,402...118,258,329
G
Glce
glucuronic acid epimerase
decreases expression
ISO
Amphotericin B analog results in decreased expression of GLCE mRNA
CTD
PMID:28534445
NCBI chr 8:62,546,104...62,612,144
Ensembl chr 8:62,546,107...62,612,040
G
Glod4
glyoxalase domain containing 4
decreases expression
ISO
Amphotericin B results in decreased expression of GLOD4 mRNA
CTD
PMID:20849824
NCBI chr10:61,077,535...61,095,876
Ensembl chr10:61,066,421...61,095,898
G
Gls
glutaminase
increases expression
ISO
Amphotericin B analog results in increased expression of GLS mRNA
CTD
PMID:28534445
NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
G
Glul
glutamate-ammonia ligase
decreases expression
ISO
Amphotericin B analog results in decreased expression of GLUL mRNA
CTD
PMID:28534445
NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
G
Gp1ba
glycoprotein Ib platelet subunit alpha
increases expression
ISO
Amphotericin B analog results in increased expression of GP1BA mRNA
CTD
PMID:28534445
NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
G
Gpr20
G protein-coupled receptor 20
increases expression
ISO
Amphotericin B results in increased expression of GPR20 mRNA
CTD
PMID:20849824
NCBI chr 7:105,601,761...105,611,959
Ensembl chr 7:105,602,368...105,603,430
G
Gpt
glutamic--pyruvic transaminase
multiple interactions
ISO
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein
CTD
PMID:36464106
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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Grid2
glutamate ionotropic receptor delta type subunit 2
increases expression
ISO
Amphotericin B analog results in increased expression of GRID2 mRNA
CTD
PMID:28534445
NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355
G
Grm6
glutamate metabotropic receptor 6
increases expression
ISO
Amphotericin B analog results in increased expression of GRM6 mRNA
CTD
PMID:28534445
NCBI chr10:35,167,985...35,182,717
Ensembl chr10:35,167,985...35,182,717
G
Gstp1
glutathione S-transferase pi 1
decreases expression multiple interactions
EXP ISO
Amphotericin B results in decreased expression of GSTP1 mRNA Amphotericin B inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]
CTD
PMID:20623750 PMID:23769903
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
Gstt1
glutathione S-transferase theta 1
decreases expression
EXP
Amphotericin B results in decreased expression of GSTT1 mRNA
CTD
PMID:20623750
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
G
H2ac4
H2A clustered histone 4
decreases expression
ISO
Amphotericin B analog results in decreased expression of HIST1H2AC mRNA
CTD
PMID:28534445
NCBI chr17:42,799,884...42,800,387
Ensembl chr17:42,799,652...42,800,381
G
Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions decreases activity
ISO
Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]; Amphotericin B inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]; Amphotericin B promotes the reaction [HIF1AN protein binds to and results in increased hydroxylation of and results in decreased activity of HIF1A protein] Amphotericin B results in decreased activity of HIF1A protein
CTD
PMID:16189267
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
G
Hif1an
hypoxia inducible factor 1 subunit alpha inhibitor
multiple interactions
ISO
Amphotericin B promotes the reaction [HIF1AN protein binds to and results in increased hydroxylation of and results in decreased activity of HIF1A protein]
CTD
PMID:16189267
NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327
G
Hilpda
hypoxia inducible lipid droplet-associated
decreases expression
ISO
Amphotericin B analog results in decreased expression of HILPDA mRNA
CTD
PMID:28534445
NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
G
Hipk1
homeodomain interacting protein kinase 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of HIPK1 mRNA
CTD
PMID:28534445
NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
multiple interactions
ISO
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA
CTD
PMID:36464106
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
G
Hmox1
heme oxygenase 1
increases expression
ISO
Amphotericin B analog results in increased expression of HMOX1 mRNA; Amphotericin B results in increased expression of HMOX1 mRNA
CTD
PMID:28534445
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hook1
hook microtubule-tethering protein 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of HOOK1 mRNA
CTD
PMID:28534445
NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:110,824,501...110,887,787
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Hoxd3
homeo box D3
decreases expression
ISO
Amphotericin B analog results in decreased expression of HOXD3 mRNA
CTD
PMID:28534445
NCBI chr 3:59,638,708...59,650,282
Ensembl chr 3:59,638,708...59,650,282
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Hoxd4
homeo box D4
decreases expression
ISO
Amphotericin B analog results in decreased expression of HOXD4 mRNA
CTD
PMID:28534445
NCBI chr 3:59,614,464...59,634,042
Ensembl chr 3:59,614,464...59,631,528
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Hpx
hemopexin
increases expression
ISO
Amphotericin B analog results in increased expression of HPX mRNA
CTD
PMID:28534445
NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
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Hspa1a
heat shock protein family A (Hsp70) member 1A
decreases expression
ISO
Amphotericin B analog results in decreased expression of HSPA1A mRNA
CTD
PMID:28534445
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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Hspa1b
heat shock protein family A (Hsp70) member 1B
decreases expression
ISO
Amphotericin B analog results in decreased expression of HSPA1B mRNA
CTD
PMID:28534445
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
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Hspa2
heat shock protein family A (Hsp70) member 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of HSPA2 mRNA
CTD
PMID:28534445
NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
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Hspa8
heat shock protein family A (Hsp70) member 8
multiple interactions
ISO
Amphotericin B results in increased expression of and results in increased secretion of HSPA8 protein
CTD
PMID:26259607
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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Hspb3
heat shock protein family B (small) member 3
increases expression
ISO
Amphotericin B analog results in increased expression of HSPB3 mRNA
CTD
PMID:28534445
NCBI chr 2:45,295,285...45,295,999
Ensembl chr 2:45,295,053...45,296,145
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Htr3a
5-hydroxytryptamine receptor 3A
increases expression
ISO
Amphotericin B analog results in increased expression of HTR3A mRNA
CTD
PMID:28534445
NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
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Icam1
intercellular adhesion molecule 1
increases expression
ISO
Amphotericin B analog results in increased expression of ICAM1 mRNA; Amphotericin B results in increased expression of ICAM1 mRNA
CTD
PMID:28534445
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Id2
inhibitor of DNA binding 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of ID2 mRNA
CTD
PMID:28534445
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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Id4
inhibitor of DNA binding 4
decreases expression
ISO
Amphotericin B analog results in decreased expression of ID4 mRNA; Amphotericin B results in decreased expression of ID4 mRNA
CTD
PMID:28534445
NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470
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Ifng
interferon gamma
multiple interactions increases expression
ISO
[Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Antimony Sodium Gluconate co-treated with Amphotericin B] results in increased expression of IFNG protein Amphotericin B analog results in increased expression of IFNG mRNA
CTD
PMID:17911647 PMID:28534445 PMID:29594315
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Ifngr1
interferon gamma receptor 1
increases expression
ISO
Amphotericin B results in increased expression of IFNGR1
CTD
PMID:12803856
NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
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Igfbp5
insulin-like growth factor binding protein 5
decreases expression
ISO
Amphotericin B results in decreased expression of IGFBP5 mRNA
CTD
PMID:20849824
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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Il10
interleukin 10
multiple interactions
ISO
[Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of IL10 protein
CTD
PMID:17911647
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il13ra2
interleukin 13 receptor subunit alpha 2
increases expression
ISO
Amphotericin B analog results in increased expression of IL13RA2 mRNA
CTD
PMID:28534445
NCBI chr X:111,002,590...111,074,053
Ensembl chr X:111,002,592...111,072,381
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Il1b
interleukin 1 beta
increases expression
ISO
Amphotericin B results in increased expression of IL1B mRNA
CTD
PMID:29594315
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il1r2
interleukin 1 receptor type 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of IL1R2 mRNA
CTD
PMID:28534445
NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
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Il1rapl2
interleukin 1 receptor accessory protein-like 2
increases expression
ISO
Amphotericin B analog results in increased expression of IL1RAPL2 mRNA
CTD
PMID:28534445
NCBI chr X:100,961,509...102,271,753
Ensembl chr X:100,961,812...102,271,753
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Il2
interleukin 2
multiple interactions
ISO
[Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA
CTD
PMID:29594315
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Il6
interleukin 6
increases expression
ISO
Amphotericin B analog results in increased expression of IL6 mRNA
CTD
PMID:28534445
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Inhba
inhibin subunit beta A
increases expression
ISO
Amphotericin B analog results in increased expression of INHBA mRNA
CTD
PMID:28534445
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
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Ino80b
INO80 complex subunit B
decreases expression
ISO
Amphotericin B analog results in decreased expression of INO80B mRNA
CTD
PMID:28534445
NCBI chr 4:115,627,907...115,631,069
Ensembl chr 4:115,627,908...115,631,456
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Insig1
insulin induced gene 1
increases expression
ISO
Amphotericin B analog results in increased expression of INSIG1 mRNA; Amphotericin B results in increased expression of INSIG1 mRNA
CTD
PMID:28534445
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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Irf5
interferon regulatory factor 5
increases expression
ISO
Amphotericin B analog results in increased expression of IRF5 mRNA
CTD
PMID:28534445
NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
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Jag1
jagged canonical Notch ligand 1
decreases expression
ISO
Amphotericin B results in decreased expression of JAG1 mRNA
CTD
PMID:28534445
NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
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Kazn
kazrin, periplakin interacting protein
increases expression
ISO
Amphotericin B analog results in increased expression of KAZN mRNA
CTD
PMID:28534445
NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074
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Kcnb1
potassium voltage-gated channel subfamily B member 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of KCNB1 mRNA
CTD
PMID:28534445
NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
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Kcnq4
potassium voltage-gated channel subfamily Q member 4
decreases expression
ISO
Amphotericin B results in decreased expression of KCNQ4 mRNA
CTD
PMID:20849824
NCBI chr 5:134,275,145...134,326,992
Ensembl chr 5:134,275,934...134,326,932
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Klf12
KLF transcription factor 12
increases expression
ISO
Amphotericin B analog results in increased expression of KLF12 mRNA
CTD
PMID:28534445
NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
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Klf9
KLF transcription factor 9
decreases expression
ISO
Amphotericin B analog results in decreased expression of KLF9 mRNA
CTD
PMID:28534445
NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037
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Klhl24
kelch-like family member 24
decreases expression
ISO
Amphotericin B analog results in decreased expression of KLHL24 mRNA
CTD
PMID:28534445
NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636
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Klrb1a
killer cell lectin like receptor B1A
increases expression
ISO
Amphotericin B analog results in increased expression of KLRB1 mRNA
CTD
PMID:28534445
NCBI chr 4:161,890,577...161,904,050
Ensembl chr 4:161,890,577...161,961,675
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Kmo
kynurenine 3-monooxygenase
decreases expression
ISO
Amphotericin B analog results in decreased expression of KMO mRNA
CTD
PMID:28534445
NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
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Lalba
lactalbumin, alpha
increases expression
ISO
Amphotericin B analog results in increased expression of LALBA mRNA
CTD
PMID:28534445
NCBI chr 7:129,625,531...129,628,034
Ensembl chr 7:129,625,535...129,628,061
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Lcn2
lipocalin 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of LCN2 mRNA
CTD
PMID:28534445
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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Ldlr
low density lipoprotein receptor
multiple interactions
ISO
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA
CTD
PMID:36464106
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Ldlrad4
low density lipoprotein receptor class A domain containing 4
increases expression
ISO
Amphotericin B analog results in increased expression of LDLRAD4 mRNA
CTD
PMID:28534445
NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
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Lgals4
galectin 4
increases expression
ISO
Amphotericin B analog results in increased expression of LGALS4 mRNA
CTD
PMID:28534445
NCBI chr 1:84,124,766...84,132,481
Ensembl chr 1:84,124,764...84,132,481
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Limk1
LIM domain kinase 1
increases expression
ISO
Amphotericin B analog results in increased expression of LIMK1 mRNA
CTD
PMID:28534445
NCBI chr12:22,026,697...22,060,605
Ensembl chr12:22,026,672...22,060,606
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Lpin1
lipin 1
multiple interactions
ISO
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA
CTD
PMID:36464106
NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
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Lsg1
large 60S subunit nuclear export GTPase 1
decreases expression
ISO
Amphotericin B results in decreased expression of LSG1 mRNA
CTD
PMID:20849824
NCBI chr11:70,132,919...70,168,526
Ensembl chr11:70,143,847...70,168,518
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Lyst
lysosomal trafficking regulator
increases expression
ISO
Amphotericin B analog results in increased expression of LYST mRNA
CTD
PMID:28534445
NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480
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Madcam1
mucosal vascular addressin cell adhesion molecule 1
increases expression
ISO
Amphotericin B analog results in increased expression of MADCAM1 mRNA
CTD
PMID:28534445
NCBI chr 7:10,036,301...10,039,703
Ensembl chr 7:10,036,301...10,039,703
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Maf
MAF bZIP transcription factor
decreases expression
ISO
Amphotericin B analog results in decreased expression of MAF mRNA
CTD
PMID:28534445
NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
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Maoa
monoamine oxidase A
decreases expression
ISO
Amphotericin B analog results in decreased expression of MAOA mRNA
CTD
PMID:28534445
NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases expression
ISO
Amphotericin B results in increased expression of MAP1LC3B protein
CTD
PMID:23988732
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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Map3k19
mitogen-activated protein kinase kinase kinase 19
increases expression
ISO
Amphotericin B analog results in increased expression of MAP3K19 mRNA
CTD
PMID:28534445
NCBI chr13:39,300,150...39,343,502
Ensembl chr13:39,300,163...39,343,767
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Mcm3ap
minichromosome maintenance complex component 3 associated protein
increases expression
ISO
Amphotericin B analog results in increased expression of MCM3AP mRNA
CTD
PMID:28534445
NCBI chr20:12,127,570...12,165,165
Ensembl chr20:12,127,570...12,165,165
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Meak7
MTOR associated protein, eak-7 homolog
increases expression
ISO
Amphotericin B analog results in increased expression of TLDC1 mRNA
CTD
PMID:28534445
NCBI chr19:47,813,899...47,836,830
Ensembl chr19:47,811,416...47,841,278
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Mef2c
myocyte enhancer factor 2C
decreases expression
ISO
Amphotericin B analog results in decreased expression of MEF2C mRNA
CTD
PMID:28534445
NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
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Mir106b
microRNA 106b
increases expression
ISO
Amphotericin B analog results in increased expression of MIR106B
CTD
PMID:28534445
NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425
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Mir138-1
microRNA 138-1
increases expression
ISO
Amphotericin B results in increased expression of MIR138
CTD
PMID:28534445
NCBI chr 8:122,300,966...122,301,064
Ensembl chr 8:122,300,966...122,301,064
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Mir17
microRNA 17
increases expression
ISO
Amphotericin B analog results in increased expression of MIR17
CTD
PMID:28534445
NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
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Mir181c
microRNA 181c
increases expression
ISO
Amphotericin B analog results in increased expression of MIR181C
CTD
PMID:28534445
NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
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Mir181d
microRNA 181d
decreases expression
ISO
Amphotericin B analog results in decreased expression of MIR181D
CTD
PMID:28534445
NCBI chr19:23,983,706...23,983,788
Ensembl chr19:23,983,706...23,983,788
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Mir423
microRNA 423
increases expression
ISO
Amphotericin B analog results in increased expression of MIR423; Amphotericin B results in increased expression of MIR423
CTD
PMID:28534445
NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
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Mir494
microRNA 494
decreases expression
ISO
Amphotericin B analog results in decreased expression of MIR494; Amphotericin B results in decreased expression of MIR494
CTD
PMID:28534445
NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
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Mir99b
microRNA 99b
increases expression
ISO
Amphotericin B analog results in increased expression of MIR99B
CTD
PMID:28534445
NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:58,677,011...58,677,090
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Mirlet7g
microRNA let-7g
decreases expression
ISO
Amphotericin B analog results in decreased expression of MIRLET7G
CTD
PMID:28534445
NCBI chr 8:106,822,293...106,822,380
Ensembl chr 8:106,822,280...106,822,388
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Mmp28
matrix metallopeptidase 28
decreases expression
ISO
Amphotericin B analog results in decreased expression of MMP28 mRNA
CTD
PMID:28534445
NCBI chr10:68,241,138...68,264,866
Ensembl chr10:68,241,138...68,264,866
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Mphosph8
M-phase phosphoprotein 8
decreases expression
ISO
Amphotericin B analog results in decreased expression of MPHOSPH8 mRNA
CTD
PMID:28534445
NCBI chr15:30,800,546...30,828,415
Ensembl chr15:30,686,613...30,828,810
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Mtf2
metal response element binding transcription factor 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of MTF2 mRNA
CTD
PMID:28534445
NCBI chr14:1,639,256...1,683,513
Ensembl chr14:1,640,746...1,683,524
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Muc2
mucin 2, oligomeric mucus/gel-forming
increases expression
ISO
Amphotericin B analog results in increased expression of MUC2 mRNA
CTD
PMID:28534445
NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756
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Mx2
MX dynamin like GTPase 2
increases expression
ISO
Amphotericin B analog results in increased expression of MX2 mRNA
CTD
PMID:28534445
NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
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Myo15b
myosin XVB
increases expression
ISO
Amphotericin B analog results in increased expression of MYO15B mRNA
CTD
PMID:28534445
NCBI chr10:101,088,734...101,126,159
Ensembl chr10:101,104,209...101,125,693
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Myo7a
myosin VIIA
increases expression
ISO
Amphotericin B analog results in increased expression of MYO7A mRNA
CTD
PMID:28534445
NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157
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Nat8
N-acetyltransferase 8
decreases expression
ISO
Amphotericin B analog results in decreased expression of NAT8 mRNA
CTD
PMID:28534445
NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763
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Nedd9
neural precursor cell expressed, developmentally down-regulated 9
decreases expression
ISO
Amphotericin B analog results in decreased expression of NEDD9 mRNA
CTD
PMID:28534445
NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
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Nefl
neurofilament light chain
decreases expression
ISO
Amphotericin B analog results in decreased expression of NEFL mRNA
CTD
PMID:28534445
NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
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Nefm
neurofilament medium chain
decreases expression
ISO
Amphotericin B analog results in decreased expression of NEFM mRNA
CTD
PMID:28534445
NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
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Nf2
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor
decreases expression
ISO
Amphotericin B analog results in decreased expression of NF2 mRNA
CTD
PMID:28534445
NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667
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Nol3
nucleolar protein 3
decreases expression
ISO
Amphotericin B analog results in decreased expression of NOL3 mRNA
CTD
PMID:28534445
NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
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Nprl2
NPR2-like, GATOR1 complex subunit
decreases expression
ISO
Amphotericin B results in decreased expression of NPRL2 mRNA
CTD
PMID:20849824
NCBI chr 8:108,215,823...108,218,996
Ensembl chr 8:108,215,814...108,218,996
G
Nr2e1
nuclear receptor subfamily 2, group E, member 1
increases expression
ISO
Amphotericin B analog results in increased expression of NR2E1 mRNA
CTD
PMID:28534445
NCBI chr20:46,050,134...46,071,257
Ensembl chr20:46,050,414...46,073,949
G
Nr2f1
nuclear receptor subfamily 2, group F, member 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of NR2F1 mRNA
CTD
PMID:28534445
NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
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Nt5c2
5'-nucleotidase, cytosolic II
increases expression
ISO
Amphotericin B results in increased expression of NT5C2 mRNA
CTD
PMID:20849824
NCBI chr 1:245,770,993...245,896,925
Ensembl chr 1:245,772,277...245,897,913
G
Ntrk2
neurotrophic receptor tyrosine kinase 2
decreases expression increases expression
ISO
Amphotericin B analog results in decreased expression of NTRK2 mRNA Amphotericin B analog results in increased expression of NTRK2 mRNA
CTD
PMID:28534445
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
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Or10j2
olfactory receptor family 10 subfamily J member 2
increases expression
ISO
Amphotericin B analog results in increased expression of OR10J1 mRNA
CTD
PMID:28534445
NCBI chr13:85,723,300...85,724,290
Ensembl chr13:85,719,234...85,724,767
G
Or2h2c
olfactory receptor family 2 subfamily H member 2C
increases expression
ISO
Amphotericin B analog results in increased expression of OR2H2 mRNA
CTD
PMID:28534445
NCBI chr20:1,398,964...1,399,902
Ensembl chr20:1,395,108...1,400,441
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Ovol2
ovo-like zinc finger 2
increases expression
ISO
Amphotericin B analog results in increased expression of OVOL2 mRNA
CTD
PMID:28534445
NCBI chr 3:131,677,391...131,707,123
Ensembl chr 3:131,677,391...131,708,359
G
Paip1
poly(A) binding protein interacting protein 1
decreases expression
ISO
Amphotericin B results in decreased expression of PAIP1 mRNA
CTD
PMID:20849824
NCBI chr 2:51,523,190...51,550,241
Ensembl chr 2:51,522,921...51,550,241
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Pard3
par-3 family cell polarity regulator
decreases expression
ISO
Amphotericin B results in decreased expression of PARD3 mRNA
CTD
PMID:20849824
NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778
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Pard6b
par-6 family cell polarity regulator beta
increases expression
ISO
Amphotericin B analog results in increased expression of PARD6B mRNA
CTD
PMID:28534445
NCBI chr 3:156,790,540...156,811,620
Ensembl chr 3:156,790,540...156,811,622
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Pde1a
phosphodiesterase 1A
decreases expression
ISO
Amphotericin B analog results in decreased expression of PDE1A mRNA
CTD
PMID:28534445
NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874
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Pde4d
phosphodiesterase 4D
decreases expression
ISO
Amphotericin B analog results in decreased expression of PDE4D mRNA
CTD
PMID:28534445
NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
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Pde4dip
phosphodiesterase 4D interacting protein
decreases expression
ISO
Amphotericin B analog results in decreased expression of PDE4DIP mRNA
CTD
PMID:28534445
NCBI chr 2:185,293,236...185,490,100
Ensembl chr 2:185,293,214...185,468,379
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Pdlim7
PDZ and LIM domain 7
decreases expression
ISO
Amphotericin B analog results in decreased expression of PDLIM7 mRNA
CTD
PMID:28534445
NCBI chr17:9,124,565...9,139,814
Ensembl chr17:9,124,649...9,139,811
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Pecam1
platelet and endothelial cell adhesion molecule 1
increases expression
ISO
Amphotericin B analog results in increased expression of PECAM1 mRNA
CTD
PMID:28534445
NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
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Pgk1
phosphoglycerate kinase 1
multiple interactions
ISO
Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of PGK1 mRNA]
CTD
PMID:16189267
NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418
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Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of PIK3R1 mRNA
CTD
PMID:28534445
NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
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Pitx2
paired-like homeodomain 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of PITX2 mRNA; Amphotericin B results in decreased expression of PITX2 mRNA
CTD
PMID:28534445
NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293
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Pklr
pyruvate kinase L/R
increases expression
ISO
Amphotericin B analog results in increased expression of PKLR mRNA
CTD
PMID:28534445
NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
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Pkp1
plakophilin 1
increases expression
ISO
Amphotericin B analog results in increased expression of PKP1 mRNA
CTD
PMID:28534445
NCBI chr13:47,309,607...47,357,432
Ensembl chr13:47,309,614...47,357,465
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Pla2g2a
phospholipase A2 group IIA
increases expression
ISO
Amphotericin B analog results in increased expression of PLA2G2A mRNA
CTD
PMID:28534445
NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
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Plcb1
phospholipase C beta 1
increases expression
ISO
Amphotericin B analog results in increased expression of PLCB1 mRNA
CTD
PMID:28534445
NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869
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Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
increases expression
ISO
Amphotericin B analog results in increased expression of PMAIP1 mRNA
CTD
PMID:28534445
NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
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Polg
DNA polymerase gamma, catalytic subunit
increases expression
ISO
Amphotericin B analog results in increased expression of POLG mRNA; Amphotericin B results in increased expression of POLG mRNA
CTD
PMID:28534445
NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567
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Polm
DNA polymerase mu
increases expression
ISO
Amphotericin B results in increased expression of POLM mRNA
CTD
PMID:20849824
NCBI chr14:80,707,075...80,716,677
Ensembl chr14:80,706,345...80,717,086
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Ppl
periplakin
decreases expression
ISO
Amphotericin B analog results in decreased expression of PPL mRNA
CTD
PMID:28534445
NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575
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Ppp1r3c
protein phosphatase 1, regulatory subunit 3C
decreases expression
ISO
Amphotericin B analog results in decreased expression of PPP1R3C mRNA
CTD
PMID:28534445
NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
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Psat1
phosphoserine aminotransferase 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of PSAT1 mRNA
CTD
PMID:28534445
NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
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Ptpn22
protein tyrosine phosphatase, non-receptor type 22
decreases expression
ISO
Amphotericin B analog results in decreased expression of PTPN22 mRNA
CTD
PMID:28534445
NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
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Ptprt
protein tyrosine phosphatase, receptor type, T
increases expression
ISO
Amphotericin B analog results in increased expression of PTPRT mRNA
CTD
PMID:28534445
NCBI chr 3:150,189,343...151,288,145
Ensembl chr 3:150,194,859...151,288,124
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Rad54b
RAD54 homolog B
increases expression
ISO
Amphotericin B analog results in increased expression of RAD54B mRNA
CTD
PMID:28534445
NCBI chr 5:25,032,112...25,104,630
Ensembl chr 5:25,032,066...25,104,616
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Ramp3
receptor activity modifying protein 3
increases expression
ISO
Amphotericin B analog results in increased expression of RAMP3 mRNA
CTD
PMID:28534445
NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902
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Rarres1
retinoic acid receptor responder 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of RARRES1 mRNA
CTD
PMID:28534445
NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
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Rasgrp1
RAS guanyl releasing protein 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of RASGRP1 mRNA
CTD
PMID:28534445
NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
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Rbbp5
RB binding protein 5, histone lysine methyltransferase complex subunit
decreases expression
ISO
Amphotericin B analog results in decreased expression of RBBP5 mRNA; Amphotericin B results in decreased expression of RBBP5 mRNA
CTD
PMID:28534445
NCBI chr13:43,912,254...43,939,107
Ensembl chr13:43,912,254...43,939,107
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Rbm47
RNA binding motif protein 47
decreases expression
ISO
Amphotericin B analog results in decreased expression of RBM47 mRNA
CTD
PMID:28534445
NCBI chr14:42,053,290...42,191,572
Ensembl chr14:42,154,142...42,189,431
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Rcan2
regulator of calcineurin 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of RCAN2 mRNA
CTD
PMID:28534445
NCBI chr 9:16,959,478...17,174,823
Ensembl chr 9:16,959,480...17,174,856
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Rel
REL proto-oncogene, NF-kB subunit
decreases expression
ISO
Amphotericin B analog results in decreased expression of REL mRNA
CTD
PMID:28534445
NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
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Reps2
RALBP1 associated Eps domain containing 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of REPS2 mRNA
CTD
PMID:28534445
NCBI chr X:32,049,455...32,322,317
Ensembl chr X:32,049,399...32,317,414
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Rgs2
regulator of G-protein signaling 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of RGS2 mRNA; Amphotericin B results in decreased expression of RGS2 mRNA
CTD
PMID:28534445
NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
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Rhd
Rh blood group, D antigen
increases expression
ISO
Amphotericin B analog results in increased expression of RHD mRNA
CTD
PMID:28534445
NCBI chr 5:147,087,479...147,121,716
Ensembl chr 5:147,087,518...147,121,715
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Ripor2
RHO family interacting cell polarization regulator 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of FAM65B mRNA; Amphotericin B results in decreased expression of FAM65B mRNA
CTD
PMID:28534445
NCBI chr17:40,323,748...40,547,482
Ensembl chr17:40,323,867...40,548,092
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Rmnd5a
required for meiotic nuclear division 5 homolog A
decreases expression
ISO
Amphotericin B analog results in decreased expression of RMND5A mRNA
CTD
PMID:28534445
NCBI chr 4:103,375,846...103,432,890
Ensembl chr 4:103,379,908...103,433,051
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Rnase4
ribonuclease A family member 4
decreases expression
ISO
Amphotericin B analog results in decreased expression of RNASE4 mRNA
CTD
PMID:28534445
NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
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Rnd3
Rho family GTPase 3
increases expression
ISO
Amphotericin B results in increased expression of RND3 mRNA
CTD
PMID:28534445
NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
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Rora
RAR-related orphan receptor A
decreases expression
ISO
Amphotericin B analog results in decreased expression of RORA mRNA
CTD
PMID:28534445
NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
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Rps8
ribosomal protein S8
increases expression
ISO
Amphotericin B analog results in increased expression of RPS8 mRNA
CTD
PMID:28534445
NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
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Rrad
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
decreases expression
ISO
Amphotericin B analog results in decreased expression of RRAD mRNA
CTD
PMID:28534445
NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
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Rsl1d1
ribosomal L1 domain containing 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of RSL1D1 mRNA
CTD
PMID:28534445
NCBI chr10:4,424,868...4,436,753
Ensembl chr10:4,397,821...4,439,593
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RT1-CE5
RT1 class I, locus CE5
increases expression
ISO
Amphotericin B results in increased expression of HLA-F mRNA
CTD
PMID:20849824
NCBI chr20:3,403,418...3,479,476
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Rtn1
reticulon 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of RTN1 mRNA
CTD
PMID:28534445
NCBI chr 6:90,763,212...90,983,436
Ensembl chr 6:90,763,216...90,983,436
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Runx3
RUNX family transcription factor 3
decreases expression
ISO
Amphotericin B results in decreased expression of RUNX3 mRNA
CTD
PMID:20849824
NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156
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Sap30
Sin3A associated protein 30
increases expression
ISO
Amphotericin B analog results in increased expression of SAP30 mRNA
CTD
PMID:28534445
NCBI chr16:32,747,777...32,753,114
Ensembl chr16:32,747,734...32,753,112
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Scnn1a
sodium channel epithelial 1 subunit alpha
decreases expression
ISO
Amphotericin B analog results in decreased expression of SCNN1A mRNA
CTD
PMID:28534445
NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181
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Serpina5
serpin family A member 5
decreases expression
ISO
Amphotericin B analog results in decreased expression of SERPINA5 mRNA
CTD
PMID:28534445
NCBI chr 6:123,009,224...123,028,412
Ensembl chr 6:123,023,306...123,028,407
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Serpinb3a
serpin family B member 3A
decreases expression
ISO
Amphotericin B analog results in decreased expression of SERPINB4 mRNA
CTD
PMID:28534445
NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985
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Sgk3
serum/glucocorticoid regulated kinase family, member 3
decreases expression
ISO
Amphotericin B results in decreased expression of SGK3 mRNA
CTD
PMID:28534445
NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476
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Siglec1
sialic acid binding Ig like lectin 1
increases expression
ISO
Amphotericin B analog results in increased expression of SIGLEC1 mRNA
CTD
PMID:28534445
NCBI chr 3:118,287,988...118,307,125
Ensembl chr 3:118,287,988...118,306,850
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Sik1
salt-inducible kinase 1
increases expression
ISO
Amphotericin B analog results in increased expression of SIK1 mRNA; Amphotericin B results in increased expression of SIK1 mRNA
CTD
PMID:28534445
NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
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Slc16a6
solute carrier family 16, member 6
increases expression
ISO
Amphotericin B analog results in increased expression of SLC16A6 mRNA
CTD
PMID:28534445
NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779
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Slc22a14
solute carrier family 22, member 14
increases expression
ISO
Amphotericin B analog results in increased expression of SLC22A14 mRNA
CTD
PMID:28534445
NCBI chr 8:118,894,537...118,916,416
Ensembl chr 8:118,895,259...118,908,255
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Slc22a7
solute carrier family 22 member 7
multiple interactions
ISO
[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SLC22A7 mRNA
CTD
PMID:36464106
NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
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Slc27a2
solute carrier family 27 member 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of SLC27A2 mRNA
CTD
PMID:28534445
NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
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Slc2a5
solute carrier family 2 member 5
decreases expression
ISO
Amphotericin B analog results in decreased expression of SLC2A5 mRNA
CTD
PMID:28534445
NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
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Slc39a7
solute carrier family 39 member 7
decreases expression
ISO
Amphotericin B analog results in decreased expression of SLC39A7 mRNA
CTD
PMID:28534445
NCBI chr20:4,823,166...4,826,538
Ensembl chr20:4,822,012...4,826,537
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Slc5a1
solute carrier family 5 member 1
increases expression
ISO
Amphotericin B analog results in increased expression of SLC5A1 mRNA
CTD
PMID:28534445
NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547
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Slc6a6
solute carrier family 6 member 6
decreases expression
ISO
Amphotericin B analog results in decreased expression of SLC6A6 mRNA
CTD
PMID:28534445
NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
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Slit1
slit guidance ligand 1
decreases expression
ISO
Amphotericin B results in decreased expression of SLIT1 mRNA
CTD
PMID:20849824
NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127
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Sorbs1
sorbin and SH3 domain containing 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of SORBS1 mRNA
CTD
PMID:28534445
NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169
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Sorl1
sortilin related receptor 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of SORL1 mRNA
CTD
PMID:28534445
NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
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Spag8
sperm associated antigen 8
decreases expression
ISO
Amphotericin B analog results in decreased expression of SPAG8 mRNA
CTD
PMID:28534445
NCBI chr 5:57,901,681...57,903,894
Ensembl chr 5:57,901,682...57,903,894
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Spp1
secreted phosphoprotein 1
affects expression
EXP
Amphotericin B affects the expression of SPP1 mRNA
CTD
PMID:20623750
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Spry1
sprouty RTK signaling antagonist 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of SPRY1 mRNA
CTD
PMID:28534445
NCBI chr 2:120,557,256...120,561,917
Ensembl chr 2:120,556,706...120,566,189
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Sptbn5
spectrin, beta, non-erythrocytic 5
increases expression
ISO
Amphotericin B analog results in increased expression of SPTBN5 mRNA
CTD
PMID:28534445
NCBI chr 3:107,013,783...107,054,878
Ensembl chr 3:107,013,265...107,054,324
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Sqle
squalene epoxidase
multiple interactions
ISO
[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SQLE mRNA
CTD
PMID:36464106
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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Srebf1
sterol regulatory element binding transcription factor 1
multiple interactions
ISO
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA
CTD
PMID:36464106
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Srebf2
sterol regulatory element binding transcription factor 2
multiple interactions
ISO
[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF2 mRNA
CTD
PMID:36464106
NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
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Stc1
stanniocalcin 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of STC1 mRNA
CTD
PMID:28534445
NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
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Stmn4
stathmin 4
increases expression
ISO
Amphotericin B analog results in increased expression of STMN4 mRNA
CTD
PMID:28534445
NCBI chr15:40,541,305...40,559,253
Ensembl chr15:40,541,357...40,559,253
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Tac3
tachykinin precursor 3
increases expression
ISO
Amphotericin B analog results in increased expression of TAC3 mRNA
CTD
PMID:28534445
NCBI chr 7:63,562,552...63,569,170
Ensembl chr 7:63,562,552...63,569,170
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Tacstd2
tumor-associated calcium signal transducer 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of TACSTD2 mRNA
CTD
PMID:28534445
NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650
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Taf13
TATA-box binding protein associated factor 13
decreases expression
ISO
Amphotericin B analog results in decreased expression of TAF13 mRNA
CTD
PMID:28534445
NCBI chr 2:196,205,219...196,215,882
Ensembl chr 2:196,205,243...196,215,878
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Tal1
TAL bHLH transcription factor 1, erythroid differentiation factor
increases expression
ISO
Amphotericin B analog results in increased expression of TAL1 mRNA
CTD
PMID:28534445
NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976
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Tcf20
transcription factor 20
increases expression
ISO
Amphotericin B analog results in increased expression of TCF20 mRNA
CTD
PMID:28534445
NCBI chr 7:113,953,449...114,104,166
Ensembl chr 7:113,954,089...114,051,839
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Tenm1
teneurin transmembrane protein 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of TENM1 mRNA
CTD
PMID:28534445
NCBI chr X:121,400,466...122,289,877
Ensembl chr X:121,403,649...122,290,207
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Tent5a
terminal nucleotidyltransferase 5A
decreases expression
ISO
Amphotericin B analog results in decreased expression of FAM46A mRNA
CTD
PMID:28534445
NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045
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Tfdp2
transcription factor Dp-2
decreases expression
ISO
Amphotericin B analog results in decreased expression of TFDP2 mRNA; Amphotericin B results in decreased expression of TFDP2 mRNA
CTD
PMID:28534445
NCBI chr 8:96,760,459...96,901,466
Ensembl chr 8:96,760,504...96,896,682
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Tfec
transcription factor EC
decreases expression
ISO
Amphotericin B analog results in decreased expression of TFEC mRNA
CTD
PMID:28534445
NCBI chr 4:45,106,129...45,180,236
Ensembl chr 4:45,107,641...45,180,236
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Tff1
trefoil factor 1
increases expression
ISO
Amphotericin B analog results in increased expression of TFF1 mRNA
CTD
PMID:28534445
NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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Tgfb1
transforming growth factor, beta 1
multiple interactions
ISO
[Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of TGFB1 protein
CTD
PMID:17911647
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Themis2
thymocyte selection associated family member 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of THEMIS2 mRNA
CTD
PMID:28534445
NCBI chr 5:144,991,110...145,006,362
Ensembl chr 5:144,991,112...145,006,400
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Tmcc1
transmembrane and coiled-coil domain family 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of TMCC1 mRNA
CTD
PMID:28534445
NCBI chr 4:149,069,252...149,239,585
Ensembl chr 4:149,069,260...149,239,620
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Tmem140
transmembrane protein 140
decreases expression
ISO
Amphotericin B analog results in decreased expression of TMEM140 mRNA
CTD
PMID:28534445
NCBI chr 4:63,536,477...63,547,478
Ensembl chr 4:63,536,168...63,548,455
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Tmem151b
transmembrane protein 151B
increases expression
ISO
Amphotericin B results in increased expression of TMEM151B mRNA
CTD
PMID:28534445
NCBI chr 9:15,456,446...15,464,289
Ensembl chr 9:15,455,801...15,464,302
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Tmem176b
transmembrane protein 176B
decreases expression
ISO
Amphotericin B analog results in decreased expression of TMEM176B mRNA
CTD
PMID:28534445
NCBI chr 4:77,766,928...77,774,740
Ensembl chr 4:77,766,928...77,774,384
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Tmem255a
transmembrane protein 255A
decreases expression
ISO
Amphotericin B analog results in decreased expression of TMEM255A mRNA
CTD
PMID:28534445
NCBI chr X:116,970,793...117,035,008
Ensembl chr X:116,970,695...117,035,008
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Tmem45a
transmembrane protein 45A
decreases expression
ISO
Amphotericin B analog results in decreased expression of TMEM45A mRNA
CTD
PMID:28534445
NCBI chr11:43,713,309...43,799,526
Ensembl chr11:43,713,782...43,799,526
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Tnf
tumor necrosis factor
increases expression
EXP
Amphotericin B results in increased expression of TNF mRNA
CTD
PMID:20623750
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfaip3
TNF alpha induced protein 3
increases expression
ISO
Amphotericin B analog results in increased expression of TNFAIP3 mRNA
CTD
PMID:28534445
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
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Tnfsf4
TNF superfamily member 4
decreases expression
ISO
Amphotericin B analog results in decreased expression of TNFSF4 mRNA
CTD
PMID:28534445
NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
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Tox3
TOX high mobility group box family member 3
decreases expression
ISO
Amphotericin B analog results in decreased expression of TOX3 mRNA
CTD
PMID:28534445
NCBI chr19:16,648,338...16,757,151
Ensembl chr19:16,648,342...16,757,148
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Tp63
tumor protein p63
increases expression
ISO
Amphotericin B analog results in increased expression of TP63 mRNA
CTD
PMID:28534445
NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
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Trem1
triggering receptor expressed on myeloid cells 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of TREM1 mRNA
CTD
PMID:28534445
NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
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Trpm3
transient receptor potential cation channel, subfamily M, member 3
decreases expression
ISO
Amphotericin B analog results in decreased expression of TRPM3 mRNA
CTD
PMID:28534445
NCBI chr 1:219,673,200...220,557,610
Ensembl chr 1:219,672,892...220,560,717
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Trpm6
transient receptor potential cation channel, subfamily M, member 6
increases expression
ISO
Amphotericin B analog results in increased expression of TRPM6 mRNA
CTD
PMID:28534445
NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
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Trps1
transcriptional repressor GATA binding 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of TRPS1 mRNA
CTD
PMID:28534445
NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905
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Tssk2
testis-specific serine kinase 2
increases expression
ISO
Amphotericin B analog results in increased expression of TSSK2 mRNA
CTD
PMID:28534445
NCBI chr11:83,086,578...83,087,933
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Txnip
thioredoxin interacting protein
decreases expression
ISO
Amphotericin B analog results in decreased expression of TXNIP mRNA
CTD
PMID:28534445
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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Ube2d2b
ubiquitin-conjugating enzyme E2D 2B
increases expression
ISO
Amphotericin B analog results in increased expression of UBE2D4 mRNA
CTD
PMID:28534445
NCBI chr14:1,915,999...1,917,473
Ensembl chr14:1,916,845...1,917,416
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Ugt1a9
UDP glucuronosyltransferase family 1 member A9
affects expression
EXP
Amphotericin B affects the expression of UGT1A9 mRNA
CTD
PMID:20623750
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Usp2
ubiquitin specific peptidase 2
increases expression
ISO
Amphotericin B analog results in increased expression of USP2 mRNA
CTD
PMID:28534445
NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
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Usp36
ubiquitin specific peptidase 36
increases expression
ISO
Amphotericin B results in increased expression of USP36 mRNA
CTD
PMID:20849824
NCBI chr10:103,497,349...103,528,877
Ensembl chr10:103,497,349...103,528,877
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Vav3
vav guanine nucleotide exchange factor 3
decreases expression
ISO
Amphotericin B analog results in decreased expression of VAV3 mRNA; Amphotericin B results in decreased expression of VAV3 mRNA
CTD
PMID:28534445
NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321
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Vgll1
vestigial-like family member 1
increases expression
ISO
Amphotericin B analog results in increased expression of VGLL1 mRNA
CTD
PMID:28534445
NCBI chr X:134,979,657...134,996,007
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Vnn1
vanin 1
decreases expression
ISO
Amphotericin B analog results in decreased expression of VNN1 mRNA
CTD
PMID:28534445
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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Xpnpep2
X-prolyl aminopeptidase 2
increases expression
ISO
Amphotericin B analog results in increased expression of XPNPEP2 mRNA
CTD
PMID:28534445
NCBI chr X:127,287,765...127,317,036
Ensembl chr X:127,287,979...127,317,223
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Zbtb16
zinc finger and BTB domain containing 16
decreases expression
ISO
Amphotericin B analog results in decreased expression of ZBTB16 mRNA
CTD
PMID:28534445
NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
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Zfp236
zinc finger protein 236
increases expression
ISO
Amphotericin B analog results in increased expression of ZNF236 mRNA
CTD
PMID:28534445
NCBI chr18:75,976,478...76,072,428
Ensembl chr18:75,978,231...76,073,737
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Zfp36l2
zinc finger protein 36, C3H type-like 2
decreases expression
ISO
Amphotericin B analog results in decreased expression of ZFP36L2 mRNA
CTD
PMID:28534445
NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064
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Zfp652
zinc finger protein 652
decreases expression
ISO
Amphotericin B results in decreased expression of ZNF652 mRNA
CTD
PMID:28534445
NCBI chr10:80,626,555...80,706,397
Ensembl chr10:80,649,400...80,698,674
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Zfx
zinc finger protein X-linked
decreases expression
ISO
Amphotericin B results in decreased expression of ZFX mRNA
CTD
PMID:28534445
NCBI chr X:58,804,690...58,853,155
Ensembl chr X:58,804,691...58,853,265
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Zmat4
zinc finger, matrin type 4
increases expression
ISO
Amphotericin B analog results in increased expression of ZMAT4 mRNA
CTD
PMID:28534445
NCBI chr16:67,969,410...68,361,377
Ensembl chr16:67,969,416...68,361,202
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Havcr1
hepatitis A virus cellular receptor 1
increases expression
ISO
methylamphotericin B results in increased expression of HAVCR1 mRNA
CTD
PMID:22863853
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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Lcn2
lipocalin 2
increases expression
ISO
methylamphotericin B results in increased expression of LCN2 mRNA
CTD
PMID:22863853
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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Spp1
secreted phosphoprotein 1
increases expression
ISO
methylamphotericin B results in increased expression of SPP1 mRNA
CTD
PMID:22863853
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Timp1
TIMP metallopeptidase inhibitor 1
increases expression
ISO
methylamphotericin B results in increased expression of TIMP1 mRNA
CTD
PMID:22863853
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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