Tenm1 (teneurin transmembrane protein 1) - Rat Genome Database

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Gene: Tenm1 (teneurin transmembrane protein 1) Rattus norvegicus
Analyze
Symbol: Tenm1
Name: teneurin transmembrane protein 1
RGD ID: 1561678
Description: Predicted to enable protein heterodimerization activity and protein homodimerization activity. Predicted to be involved in positive regulation of cellular component biogenesis; positive regulation of protein phosphorylation; and regulation of transcription by RNA polymerase III. Predicted to be located in several cellular components, including extracellular region; nucleus; and perinuclear region of cytoplasm. Orthologous to human TENM1 (teneurin transmembrane protein 1); INTERACTS WITH bisphenol A; (+)-catechin (ortholog); 1,2-dichloroethane (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103690896; LOC298168; Odz1; protein Odd Oz/ten-m homolog 1; RGD1561678; similar to odd Oz/ten-m homolog 1; similar to Ten-m1; teneurin-1; teneurin-1-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X121,400,466 - 122,289,877 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX121,403,649 - 122,290,207 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X128,923,951 - 128,951,520 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0X129,034,755 - 129,336,023 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X129,005,588 - 129,870,335 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X1,895,286 - 2,529,211 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX120,513,461 - 120,912,284 (-)NCBICelera
Cytogenetic MapXq35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10225957   PMID:12000766   PMID:18082275   PMID:22209827   PMID:22698694   PMID:23026563  


Genomics

Comparative Map Data
Tenm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X121,400,466 - 122,289,877 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX121,403,649 - 122,290,207 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X128,923,951 - 128,951,520 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0X129,034,755 - 129,336,023 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X129,005,588 - 129,870,335 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X1,895,286 - 2,529,211 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX120,513,461 - 120,912,284 (-)NCBICelera
Cytogenetic MapXq35NCBI
TENM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X124,375,903 - 125,204,312 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX124,375,903 - 125,204,312 (-)EnsemblGRCh38hg38GRCh38
GRCh37X123,509,753 - 124,338,161 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X123,339,504 - 123,925,347 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X123,239,869 - 123,823,201NCBI
CeleraX123,894,317 - 124,482,247 (-)NCBICelera
Cytogenetic MapXq25NCBI
HuRefX112,890,871 - 113,481,233 (-)NCBIHuRef
CHM1_1X123,420,772 - 124,008,695 (-)NCBICHM1_1
T2T-CHM13v2.0X122,686,274 - 123,514,783 (-)NCBIT2T-CHM13v2.0
Tenm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X41,616,743 - 42,518,045 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX41,616,743 - 42,518,003 (-)EnsemblGRCm39 Ensembl
GRCm38X42,527,866 - 43,429,168 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX42,527,866 - 43,429,126 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X39,885,568 - 40,627,963 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X38,777,018 - 39,519,413 (-)NCBIMGSCv36mm8
CeleraX30,106,289 - 30,816,175 (-)NCBICelera
Cytogenetic MapXA4NCBI
Tenm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554739,770,364 - 10,337,379 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554739,557,822 - 10,342,007 (+)NCBIChiLan1.0ChiLan1.0
TENM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1X123,854,208 - 124,188,652 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X113,568,341 - 114,399,131 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X123,743,454 - 124,106,221 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX123,742,330 - 124,333,000 (-)Ensemblpanpan1.1panPan2
TENM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X95,766,173 - 96,565,995 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX95,769,881 - 96,550,190 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX81,834,945 - 82,631,500 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X97,552,681 - 98,343,304 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX97,554,737 - 98,327,487 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X94,983,680 - 95,773,782 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X96,739,997 - 97,530,092 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X96,529,991 - 97,320,597 (-)NCBIUU_Cfam_GSD_1.0
Tenm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X94,732,645 - 95,513,084 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364795,710,613 - 6,250,232 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049364795,603,944 - 6,254,846 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TENM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX101,856,267 - 102,641,186 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X101,853,340 - 102,641,299 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X116,722,711 - 117,279,311 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TENM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606537,115,445 - 37,496,618 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tenm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247973,151,434 - 3,732,909 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247973,146,824 - 3,732,968 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tenm1
2244 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX112934952138400867Rat
5685004Bss104Bone structure and strength QTL 1043.9tibia area (VT:1000281)tibia area measurement (CMO:0001382)X113805422126975220Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat

Markers in Region
DXGot62  
Rat AssemblyChrPosition (strand)SourceJBrowse
CeleraX121,122,015 - 121,122,193UniSTS
Cytogenetic MapXq11UniSTS
DXMco2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X121,505,375 - 121,505,657 (+)MAPPERmRatBN7.2
Rnor_6.0X129,028,431 - 129,028,712NCBIRnor6.0
Rnor_5.0X129,109,240 - 129,109,521UniSTSRnor5.0
RGSC_v3.4X2,438,798 - 2,439,078RGDRGSC3.4
RGSC_v3.4X2,438,799 - 2,439,078UniSTSRGSC3.4
RGSC_v3.1X2,438,798 - 2,439,078RGD
CeleraX120,619,118 - 120,619,397UniSTS
Cytogenetic MapXq11UniSTS
RH142840  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X121,514,665 - 121,514,849 (+)MAPPERmRatBN7.2
Rnor_6.0X129,037,721 - 129,037,904NCBIRnor6.0
Rnor_5.0X129,118,530 - 129,118,713UniSTSRnor5.0
RGSC_v3.4X2,428,895 - 2,429,078UniSTSRGSC3.4
CeleraX120,628,406 - 120,628,589UniSTS
Cytogenetic MapXq11UniSTS
BE106633  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X121,436,008 - 121,436,158 (+)MAPPERmRatBN7.2
Rnor_6.0X128,959,834 - 128,959,983NCBIRnor6.0
Rnor_5.0X129,040,990 - 129,041,139UniSTSRnor5.0
RGSC_v3.4X2,496,956 - 2,497,105UniSTSRGSC3.4
CeleraX120,548,924 - 120,549,073UniSTS
RH 3.4 Map5716.6UniSTS
Cytogenetic MapXq11UniSTS
AU047413  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X121,719,358 - 121,719,504 (+)MAPPERmRatBN7.2
Rnor_6.0X129,246,693 - 129,246,838NCBIRnor6.0
Rnor_5.0X129,327,512 - 129,327,657UniSTSRnor5.0
RGSC_v3.4X2,220,849 - 2,220,994UniSTSRGSC3.4
CeleraX120,829,307 - 120,829,452UniSTS
Cytogenetic MapXq11UniSTS
ODZ1_364  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X121,404,912 - 121,405,576 (+)MAPPERmRatBN7.2
Rnor_6.0X128,928,398 - 128,929,061NCBIRnor6.0
Rnor_5.0X129,010,035 - 129,010,698UniSTSRnor5.0
RGSC_v3.4X2,528,642 - 2,529,305UniSTSRGSC3.4
CeleraX120,517,908 - 120,518,571UniSTS
Cytogenetic MapXq11UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000100607   ⟹   ENSRNOP00000076979
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX121,403,649 - 122,290,207 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105078   ⟹   ENSRNOP00000096788
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX121,403,649 - 122,290,207 (-)Ensembl
RefSeq Acc Id: XM_039100429   ⟹   XP_038956357
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X121,400,466 - 122,289,877 (-)NCBI
RefSeq Acc Id: XM_039100431   ⟹   XP_038956359
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X121,400,466 - 122,289,877 (-)NCBI
RefSeq Acc Id: XM_039100432   ⟹   XP_038956360
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X121,400,466 - 122,289,877 (-)NCBI
RefSeq Acc Id: XM_039100433   ⟹   XP_038956361
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X121,400,466 - 122,289,877 (-)NCBI
RefSeq Acc Id: XM_039100434   ⟹   XP_038956362
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X121,400,466 - 122,289,877 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_038956360   ⟸   XM_039100432
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y571 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038956361   ⟸   XM_039100433
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038956362   ⟸   XM_039100434
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AQ34 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038956357   ⟸   XM_039100429
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y571 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038956359   ⟸   XM_039100431
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y571 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000076979   ⟸   ENSRNOT00000100607
RefSeq Acc Id: ENSRNOP00000096788   ⟸   ENSRNOT00000105078
Protein Domains
EGF-like   Teneurin N-terminal

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561678 AgrOrtholog
BioCyc Gene G2FUF-1225 BioCyc
Ensembl Genes ENSRNOG00000062454 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000076979 ENTREZGENE
  ENSRNOP00000076979.1 UniProtKB/TrEMBL
  ENSRNOP00000096788 ENTREZGENE
  ENSRNOP00000096788.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000100607 ENTREZGENE
  ENSRNOT00000100607.1 UniProtKB/TrEMBL
  ENSRNOT00000105078 ENTREZGENE
  ENSRNOT00000105078.1 UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.30 UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  RHS repeat-associated core UniProtKB/TrEMBL
InterPro 6-blade_b-propeller_TolB-like UniProtKB/TrEMBL
  CarboxyPept-like_regulatory UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  IPR006530 UniProtKB/TrEMBL
  Ten_N UniProtKB/TrEMBL
  Tox-GHH_dom UniProtKB/TrEMBL
NCBI Gene 298168 ENTREZGENE
PANTHER TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE UniProtKB/TrEMBL
  TENEURIN-1 UniProtKB/TrEMBL
Pfam Ten_N UniProtKB/TrEMBL
  Tox-GHH UniProtKB/TrEMBL
PhenoGen Tenm1 PhenoGen
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  TENEURIN_N UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
Superfamily-SCOP Calcium-dependent phosphotriesterase UniProtKB/TrEMBL
  DPP6 N-terminal domain-like UniProtKB/TrEMBL
  EGF/Laminin UniProtKB/TrEMBL
  NHL repeat UniProtKB/TrEMBL
  SSF49464 UniProtKB/TrEMBL
TIGRFAMs YD_repeat_2x UniProtKB/TrEMBL
UniProt A0A8I5Y571 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQ34 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Tenm1  teneurin transmembrane protein 1  LOC103690896  teneurin-1-like  Data Merged 737654 PROVISIONAL
2014-08-25 LOC103690896  teneurin-1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-05-24 Tenm1  teneurin transmembrane protein 1  LOC683585  similar to odd Oz/ten-m homolog 1  Data Merged 1643240 APPROVED
2012-10-11 Tenm1  teneurin transmembrane protein 1  RGD1561678  similar to Ten-m1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561678  similar to Ten-m1   RGD1561678_predicted  similar to Ten-m1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-19 LOC683585  similar to odd Oz/ten-m homolog 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1561678_predicted  similar to Ten-m1 (predicted)  LOC298168  similar to Ten-m1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC298168  similar to Ten-m1      Symbol and Name status set to provisional 70820 PROVISIONAL