Ddx11 (DEAD/H-box helicase 11) - Rat Genome Database

Name: Ddx11
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Ddx11 (DEAD/H-box helicase 11) Rattus norvegicus

Analyze

Symbol:

Ddx11

Name:

DEAD/H-box helicase 11

RGD ID:

1306675

Description:

Predicted to enable several functions, including 5'-3' DNA helicase activity; ATP-dependent activity, acting on RNA; and nucleic acid binding activity. Predicted to be involved in several processes, including cellular response to bleomycin; chromosome organization; and positive regulation of nucleobase-containing compound metabolic process. Predicted to be located in microtubule cytoskeleton; midbody; and nuclear lumen. Predicted to be part of Ctf18 RFC-like complex and chromatin. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Warsaw breakage syndrome. Orthologous to several human genes including DDX11 (DEAD/H-box helicase 11); INTERACTS WITH amphetamine; bisphenol A; C60 fullerene.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ATP-dependent DNA helicase DDX11; DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae); LOC316767; probable ATP-dependent DNA helicase DDX11; probable ATP-dependent RNA helicase DDX11

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DDX11 (DEAD/H-box helicase 11)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Ddx11 (DEAD/H box helicase 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ddx11 (DEAD/H-box helicase 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DDX11 (DEAD/H-box helicase 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DDX11 (DEAD/H-box helicase 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ddx11 (DEAD/H-box helicase 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DDX11 (DEAD/H-box helicase 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DDX11 (DEAD/H-box helicase 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ddx11 (DEAD/H-box helicase 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	DDX12P (DEAD/H-box helicase 12, pseudogene)	HGNC	Panther
Homo sapiens (human):	DDX11L8 (DEAD/H-box helicase 11 like 8 (pseudogene))	HGNC	Panther
Homo sapiens (human):	KHDC1L (KH domain containing 1 like)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	DDX11 (DEAD/H-box helicase 11)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	DDX12P (DEAD/H-box helicase 12, pseudogene)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ddx11 (DEAD/H box helicase 11)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	DDX11L8 (DEAD/H-box helicase 11 like 8 (pseudogene))	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ddx11 (DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG11403	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CHL1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	chl-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ddx11	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	105,833,234 - 105,862,844 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	105,833,504 - 105,862,550 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	114,113,642 - 114,133,908 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	114,111,580 - 114,132,492 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	113,624,011 - 113,649,000 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	105,004,683 - 105,029,456	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	105,109,790 - 105,239,631	NCBI
Cytogenetic Map	9	q37	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chromosome Breakage (ISO)

genetic disease (ISO)

microcephaly (ISO)

Warsaw breakage syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

amphotericin B (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

bortezomib (ISO)

butanal (ISO)

C60 fullerene (EXP)

calcitriol (ISO)

cobalt dichloride (ISO)

coumestrol (ISO)

dexamethasone (ISO)

dioxygen (ISO)

doxorubicin (EXP)

ethyl methanesulfonate (ISO)

fenvalerate (EXP)

indometacin (ISO)

lead(0) (ISO)

leflunomide (ISO)

malathion (ISO)

methapyrilene (ISO)

methyl methanesulfonate (ISO)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

potassium dichromate (ISO)

quercetin (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulindac sulfide (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to bleomycin (ISO)

cellular response to cisplatin (ISO)

cellular response to hydroxyurea (ISO)

DNA damage response (ISO)

DNA duplex unwinding (IBA,ISO)

establishment of sister chromatid cohesion (IBA)

G-quadruplex DNA unwinding (ISO)

nucleolar chromatin organization (ISO)

positive regulation of double-strand break repair (ISO)

positive regulation of sister chromatid cohesion (ISO)

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I (ISO)

replication fork processing (ISO)

sister chromatid cohesion (ISO)

Cellular Component

centrosome (ISO)

chromatin (ISO)

Ctf18 RFC-like complex (ISO)

midbody (ISO)

mitotic cohesin complex (ISO)

nucleolus (ISO)

nucleoplasm (ISO)

nucleus (IBA,ISO)

spindle pole (ISO)

Molecular Function

5'-3' DNA helicase activity (ISO)

ATP binding (IEA)

ATP-dependent activity, acting on DNA (ISO)

ATP-dependent activity, acting on RNA (ISO)

chromatin binding (ISO)

DNA binding (ISO)

DNA helicase activity (IBA,ISO)

DNA replication origin binding (ISO)

double-stranded DNA binding (ISO)

G-quadruplex DNA binding (ISO)

helicase activity (ISO)

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (IEA)

protein binding (ISO)

single-stranded DNA binding (ISO)

single-stranded RNA binding (ISO)

triplex DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9013641	PMID:10648783	PMID:16751776	PMID:17105772	PMID:17189189	PMID:18499658	PMID:18570454	PMID:20124417	PMID:23797032	PMID:26089203	PMID:26503245	PMID:27477908

Genomics

Comparative Map Data

Ddx11
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	105,833,234 - 105,862,844 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	105,833,504 - 105,862,550 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	114,113,642 - 114,133,908 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	114,111,580 - 114,132,492 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	113,624,011 - 113,649,000 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	105,004,683 - 105,029,456	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	105,109,790 - 105,239,631	NCBI
Cytogenetic Map	9	q37	NCBI

DDX11
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	31,073,860 - 31,104,799 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	31,073,860 - 31,104,799 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	31,226,794 - 31,257,733 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	31,118,046 - 31,148,992 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Cytogenetic Map	12	p11.21	NCBI
HuRef	12	30,992,012 - 31,022,870 (+)	NCBI		HuRef
CHM1_1	12	31,191,725 - 31,222,687 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	30,948,354 - 30,979,293 (+)	NCBI		T2T-CHM13v2.0

Ddx11
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	66,430,508 - 66,459,169 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	66,430,515 - 66,459,169 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	66,123,513 - 66,152,174 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	66,123,520 - 66,152,174 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	66,472,860 - 66,501,508 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	66,023,063 - 66,051,715 (+)	NCBI		MGSCv36	mm8
Celera	17	70,431,796 - 70,460,387 (+)	NCBI		Celera
Cytogenetic Map	17	E1.1	NCBI
cM Map	17	35.26	NCBI

Ddx11
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955524	1,932,729 - 1,957,231 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955524	1,932,988 - 1,957,231 (+)	NCBI	ChiLan1.0	ChiLan1.0

DDX11
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	12	65,674,095 - 65,705,031 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	55,176,165 - 55,207,123 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

DDX11
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	42,067,845 - 42,102,699 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	42,067,898 - 42,105,870 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	4,579,582 - 4,616,009 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	42,426,383 - 42,462,807 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	42,426,426 - 42,464,432 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	42,367,678 - 42,404,085 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	42,337,315 - 42,373,743 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	3,939,763 - 3,976,206 (-)	NCBI		UU_Cfam_GSD_1.0

Ddx11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	108,974,809 - 108,998,353 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936606	186,223 - 208,499 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936606	181,457 - 209,286 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DDX11
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	67,364,877 - 67,395,730 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	67,359,399 - 67,395,739 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	69,616,368 - 69,630,616 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DDX11
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	9,260,206 - 9,290,308 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	9,260,239 - 9,291,162 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666089	1,363,928 - 1,395,863 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ddx11
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	269,843 - 302,301 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	269,444 - 301,899 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ddx11
112 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	35
Count of miRNA genes:	33
Interacting mature miRNAs:	35
Transcripts:	ENSRNOT00000016536
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
61385	Edpm9	Estrogen-dependent pituitary mass QTL 9	3.43	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	63869687	108869687	Rat
731171	Glom6	Glomerulus QTL 6	2.8	0.0003	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	9	64573531	109573531	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
7794784	Mcs31	Mammary carcinoma susceptibility QTL 31	2.98		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	9	77813894	111552878	Rat

Markers in Region

RH133102

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	105,861,747 - 105,862,434 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	114,132,780 - 114,133,466	NCBI	Rnor6.0
Rnor_5.0	9	113,649,197 - 113,649,883	UniSTS	Rnor5.0
RGSC_v3.4	9	105,029,744 - 105,030,430	UniSTS	RGSC3.4
Cytogenetic Map	9	q37	UniSTS

RH143331

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	106,141,442 - 106,141,543 (+)	MAPPER	mRatBN7.2
mRatBN7.2	9	105,862,633 - 105,862,734 (-)	MAPPER	mRatBN7.2
mRatBN7.2	9	106,141,442 - 106,141,543 (-)	MAPPER	mRatBN7.2
mRatBN7.2	9	105,862,633 - 105,862,734 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	114,133,666 - 114,133,766	NCBI	Rnor6.0
Rnor_6.0	9	114,343,197 - 114,343,297	NCBI	Rnor6.0
Rnor_5.0	9	113,852,124 - 113,852,224	UniSTS	Rnor5.0
Rnor_5.0	9	113,650,083 - 113,650,183	UniSTS	Rnor5.0
RGSC_v3.4	9	105,030,630 - 105,030,730	UniSTS	RGSC3.4
RGSC_v3.4	9	105,321,046 - 105,321,146	UniSTS	RGSC3.4
Celera	9	103,342,411 - 103,342,511	UniSTS
Cytogenetic Map	9	q37	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1	24	26	16	12	16			45	20	34	1
Low	2	19	31	25	7	25	8	10	29	15	7	10	8
Below cutoff								1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008767410	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084765	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084767	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084769	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084771	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACYVU010000215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000079340 ⟹ ENSRNOP00000074629

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	105,833,504 - 105,862,550 (+)	Ensembl
Rnor_6.0 Ensembl	9	114,111,580 - 114,132,492 (+)	Ensembl

RefSeq Acc Id:

XM_039084764 ⟹ XP_038940692

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	105,833,239 - 105,862,844 (+)	NCBI

RefSeq Acc Id:

XM_039084765 ⟹ XP_038940693

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	105,833,238 - 105,862,844 (+)	NCBI

RefSeq Acc Id:

XM_039084766 ⟹ XP_038940694

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	105,833,234 - 105,860,928 (+)	NCBI

RefSeq Acc Id:

XM_039084767 ⟹ XP_038940695

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	105,838,479 - 105,862,844 (+)	NCBI

RefSeq Acc Id:

XM_039084768 ⟹ XP_038940696

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	105,838,410 - 105,862,844 (+)	NCBI

RefSeq Acc Id:

XM_039084769 ⟹ XP_038940697

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	105,844,447 - 105,862,844 (+)	NCBI

RefSeq Acc Id:

XM_039084770 ⟹ XP_038940698

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	105,844,121 - 105,862,844 (+)	NCBI

RefSeq Acc Id:

XM_039084771 ⟹ XP_038940699

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	105,844,447 - 105,862,844 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_038940692	(Get FASTA)	NCBI Sequence Viewer
	XP_038940693	(Get FASTA)	NCBI Sequence Viewer
	XP_038940694	(Get FASTA)	NCBI Sequence Viewer
	XP_038940695	(Get FASTA)	NCBI Sequence Viewer
	XP_038940696	(Get FASTA)	NCBI Sequence Viewer
	XP_038940697	(Get FASTA)	NCBI Sequence Viewer
	XP_038940698	(Get FASTA)	NCBI Sequence Viewer
	XP_038940699	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000074629
	ENSRNOP00000074629.2

RefSeq Acc Id:

ENSRNOP00000074629 ⟸ ENSRNOT00000079340

RefSeq Acc Id:	XP_038940694 ⟸ XM_039084766
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038940693 ⟸ XM_039084765
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038940692 ⟸ XM_039084764
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K8J3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038940696 ⟸ XM_039084768
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038940695 ⟸ XM_039084767
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038940698 ⟸ XM_039084770
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_038940699 ⟸ XM_039084771
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_038940697 ⟸ XM_039084769
- Peptide Label:	isoform X6

Protein Domains

Helicase ATP-binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K8J3-F1-model_v2	AlphaFold	A0A0G2K8J3	1-696	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306675	AgrOrtholog
BioCyc Gene	G2FUF-26453	BioCyc
Ensembl Genes	ENSRNOG00000051528	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000079340	ENTREZGENE
	ENSRNOT00000079340.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	DEAD_2	UniProtKB/TrEMBL
	DinG/Rad3-like	UniProtKB/TrEMBL
	DNA_helicase_DNA-repair_Rad3	UniProtKB/TrEMBL
	Helic_SF1/SF2_ATP-bd_DinG/Rad3	UniProtKB/TrEMBL
	Helicase-like_DEXD_c2	UniProtKB/TrEMBL
	Helicase_ATP-dep_c2	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
NCBI Gene	316767	ENTREZGENE
PANTHER	PTHR11472	UniProtKB/TrEMBL
	PTHR11472:SF41	UniProtKB/TrEMBL
Pfam	DEAD_2	UniProtKB/TrEMBL
	Helicase_C_2	UniProtKB/TrEMBL
PhenoGen	Ddx11	PhenoGen
PROSITE	HELICASE_ATP_BIND_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000051528	RatGTEx
SMART	DEXDc2	UniProtKB/TrEMBL
	HELICc2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A0G2K8J3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-01-13	Ddx11	DEAD/H-box helicase 11	Ddx11	DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-16	Ddx11	DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11	Ddx11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-08-02	Ddx11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11	Ddx11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Ddx11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)	Ddx11_predicted	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Ddx11_predicted	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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