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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2153
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arnt
Name: aryl hydrocarbon receptor nuclear translocator
Acc ID: CHEBI:2682
Term: amphotericin B
Definition: A macrolide antibiotic used to treat potentially life-threatening fungal infections.
Chemical ID: MESH:D000666
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7327396480464CTDAmphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]

PMID:16189267
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.