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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
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 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
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Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
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 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
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 Gene Annotator (Annotation Comparison) unavailable |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Imported Annotations - CTD | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| precursor lymphoblastic lymphoma/leukemia | ISO | RGD:1322721 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:23377183 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Recurrence | ISO | RGD:1322721 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:23377183 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene-Chemical Interaction AnnotationsGene Ontology AnnotationsMolecular Pathway AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations
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References - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | Mackiewicz M, etal., J Neurochem. 2003 Apr;85(2):348-57. |
| 3. | Mirzaee S, etal., Toxicology. 2010 Jan 12;267(1-3):159-64. Epub 2009 Nov 12. |
| 4. | OMIM Disease Annotation Pipeline |
| 5. | Pipeline to import SMPDB annotations from SMPDB into RGD |
| 6. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 7. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedComparative Map Data| Nt5c2 (Rattus norvegicus - Norway rat) |
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| NT5C2 (Homo sapiens - human) |
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| Nt5c2 (Mus musculus - house mouse) |
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| Nt5c2 (Chinchilla lanigera - long-tailed chinchilla) |
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| NT5C2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| NT5C2 (Canis lupus familiaris - dog) |
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| Nt5c2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| NT5C2 (Sus scrofa - pig) |
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Position Markers| D1Got441 |
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| AU046797 |
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| RH138834 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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RNA-SEQ Expression| testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
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| High | ||||||||||||||||
| Medium | 22 | 43 | 23 | 15 | 4 | 3 | 2 | 26 | 25 | 11 | 11 | 41 | 35 | 8 | 8 | |
| Low | 3 | 6 | ||||||||||||||
| Below cutoff |
Nucleotide Sequences| RefSeq Transcripts | XM_002728891 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_003753419 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006223765 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006223766 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006223768 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006231583 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006231584 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006231586 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008760495 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008774855 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017589894 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017590386 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_215270 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AAHX01000589 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01000590 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01000591 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01000592 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AC097752 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AC105488 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473986 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | XM_002728891 ⟹ XP_002728937 | |||||||||||||||||||
| RefSeq Status: | ||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||
| Position: |
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| Sequence: |
CAAGTAGTGCTCTGATCCGAAGCTCATGGTGCCGGGGTCGGGGCCGGGTGCGCGGCTGCGGCGGhide sequence |
| RefSeq Acc Id: | XM_003753419 ⟹ XP_003753467 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CAAGTAGTGCTCTGATCCGAAGCTCATGGTGCCGGGGTCGGGGCCGGGTGCGCGGCTGCGGCGGhide sequence |
| RefSeq Acc Id: | XM_006223765 ⟹ XP_006223827 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
TCTCCCAAAGGATCCCAACACCTACATAGCAGCTCATAACAGTATGCAGCTCCAGTTCTGGGTChide sequence |
| RefSeq Acc Id: | XM_006223766 ⟹ XP_006223828 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GACGCGCTCAGTTCCTTTGGTCTCTCTCGGCAGGCATCCTGGCCTCAGTTCTCGTGAGACGGGAhide sequence |
| RefSeq Acc Id: | XM_006223768 ⟹ XP_006223830 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GGCGGGGGCGGGGAGGGCGCGCGCCGAGGCGGCTGCGGCAGTTGCGCGCTAGGATTGCTGCCGThide sequence |
| RefSeq Acc Id: | XM_006231583 ⟹ XP_006231645 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
TCTCCCAAAGGATCCCAACACCTACATAGCAGCTCATAACAGTATGCAGCTCCAGTTCTGGGTChide sequence |
| RefSeq Acc Id: | XM_006231584 ⟹ XP_006231646 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
GACGCGCTCAGTTCCTTTGGTCTCTCTCGGCAGGCATCCTGGCCTCAGTTCTCGTGAGACGGGAhide sequence |
| RefSeq Acc Id: | XM_006231586 ⟹ XP_006231648 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
GGCGGGGGCGGGGAGGGCGCGCGCCGAGGCGGCTGCGGCAGTTGCGCGCTAGGATTGCTGCCGThide sequence |
| RefSeq Acc Id: | XM_008760495 ⟹ XP_008758717 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CATTCTATAGCTCAGGCAGGTCTCTTGCCTCAACCTAAGTGCTGACATTTGCAGACACGATACThide sequence |
| RefSeq Acc Id: | XM_008774855 ⟹ XP_008773077 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CATTCTATAGCTCAGGCAGGTCTCTTGCCTCAACCTAAGTGCTGACATTTGCAGACACGATACThide sequence |
| RefSeq Acc Id: | XM_017589894 ⟹ XP_017445383 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CTAAAGGTGTCTGCCACCTAACTCCCCTGCCCTTTTTTATTTTCAGATGAGGTTTCACTAAGTThide sequence |
| RefSeq Acc Id: | XM_017590386 ⟹ XP_017445875 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CTAAAGGTGTCTGCCACCTAACTCCCCTGCCCTTTTTTATTTTCAGATGAGGTTTCACTAAGTThide sequence |
Protein Sequences| Protein RefSeqs | XP_002728937 | (Get FASTA) | NCBI Sequence Viewer |
| XP_003753467 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006223827 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006223828 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006223830 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006231645 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006231646 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006231648 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_008758717 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_008773077 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017445383 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017445875 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_215270 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | EDL94365 | (Get FASTA) | NCBI Sequence Viewer |
| RefSeq Acc Id: | XP_002728937 ⟸ XM_002728891 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | D3ZMY7 (UniProtKB/TrEMBL) |
| - Sequence: |
MVPGSGPGARLRRDLARTRRIHPTNKMMTSWSDRLQNAADVPANMDKHALKKYRREAYHRVFVNhide sequence |
| RefSeq Acc Id: | XP_003753467 ⟸ XM_003753419 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | D3ZMY7 (UniProtKB/TrEMBL) |
| - Sequence: |
MVPGSGPGARLRRDLARTRRIHPTNKMMTSWSDRLQNAADVPANMDKHALKKYRREAYHRVFVNhide sequence |
| RefSeq Acc Id: | XP_006223827 ⟸ XM_006223765 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MQLQFWVIRCCLLASKSTRIHPTNKMMTSWSDRLQNAADVPANMDKHALKKYRREAYHRVFVNRhide sequence |
| RefSeq Acc Id: | XP_006223830 ⟸ XM_006223768 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MMTSWSDRLQNAADVPANMDKHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEhide sequence |
| RefSeq Acc Id: | XP_006223828 ⟸ XM_006223766 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MMTSWSDRLQNAADVPANMDKHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEhide sequence |
| RefSeq Acc Id: | XP_006231645 ⟸ XM_006231583 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MQLQFWVIRCCLLASKSTRIHPTNKMMTSWSDRLQNAADVPANMDKHALKKYRREAYHRVFVNRhide sequence |
| RefSeq Acc Id: | XP_006231648 ⟸ XM_006231586 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MMTSWSDRLQNAADVPANMDKHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEhide sequence |
| RefSeq Acc Id: | XP_006231646 ⟸ XM_006231584 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MMTSWSDRLQNAADVPANMDKHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEhide sequence |
| RefSeq Acc Id: | XP_008773077 ⟸ XM_008774855 |
| - Peptide Label: | isoform X5 |
| - Sequence: |
MRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLNFAYDSTFPhide sequence |
| RefSeq Acc Id: | XP_008758717 ⟸ XM_008760495 |
| - Peptide Label: | isoform X5 |
| - Sequence: |
MRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLNFAYDSTFPhide sequence |
| RefSeq Acc Id: | XP_017445383 ⟸ XM_017589894 |
| - Peptide Label: | isoform X4 |
| - Sequence: |
MSKEGVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLNFAYDShide sequence |
| RefSeq Acc Id: | XP_017445875 ⟸ XM_017590386 |
| - Peptide Label: | isoform X4 |
| - Sequence: |
MSKEGVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLNFAYDShide sequence |
TranscriptomeStrain Sequence Variants (Rnor 6.0)
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Damaging Variants| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 1 | 274213439 | 274213440 | C | T | snv | SBN/Ygl (MCW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), SBH/Ygl (MCW) |
| 1 | 274213482 | 274213483 | C | G | snv | FHL/EurMcwi (MCW), SBN/Ygl (MCW) |
| 1 | 274213548 | 274213549 | C | T | snv | SBN/Ygl (MCW), SBH/Ygl (MCW), FHL/EurMcwi (MCW) |
| 1 | 274213612 | 274213613 | C | A | snv | FHL/EurMcwi (MCW), SBN/Ygl (MCW) |
| 1 | 274213634 | 274213635 | G | C | snv | SBH/Ygl (MCW), FHH/EurMcwi (MCW) |
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 1 | 266662869 | 266662870 | A | G | snv | Buf/N (MCW) |
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 1 | 252209438 | 252209439 | A | G | snv | BUF/N (KNAW), BN/NHsdMcwi (KNAW), LE/Stm (KNAW) |
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:2323387 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000020179 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000027351 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000027351 | ENTREZGENE, UniProtKB/TrEMBL |
| Gene3D-CATH | 3.40.50.1000 | UniProtKB/TrEMBL |
| InterPro | HAD-like_dom | UniProtKB/TrEMBL |
| HAD-like_sf | UniProtKB/TrEMBL | |
| HAD-SF_hydro_IG_5-nucl | UniProtKB/TrEMBL | |
| Pur_nucleotidase | UniProtKB/TrEMBL | |
| KEGG Report | rno:100363253 | UniProtKB/TrEMBL |
| NCBI Gene | 100363253 | ENTREZGENE |
| PANTHER | HAD-SF_hydro_IG_5-nucl | UniProtKB/TrEMBL |
| Pfam | 5_nucleotid | UniProtKB/TrEMBL |
| PhenoGen | Nt5c2 | PhenoGen |
| PIRSF | Purine_5'-nucleotidase | UniProtKB/TrEMBL |
| Superfamily-SCOP | HAD-like_dom | UniProtKB/TrEMBL |
| TIGRFAMs | HAD-IG-Ncltidse | UniProtKB/TrEMBL |
| UniGene | Rn.22996 | |
| UniProt | D3ZMY7 | ENTREZGENE, UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2012-09-11 | Nt5c2 | 5'-nucleotidase, cytosolic II | LOC100363253 | 5'-nucleotidase, cytosolic II | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2010-05-06 | LOC100363253 | 5'-nucleotidase, cytosolic II | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
| 2008-04-30 | Nt5c2 | 5'-nucleotidase, cytosolic II | Nt5c2_predicted | 5'-nucleotidase, cytosolic II (predicted) | 'predicted' is removed | 2292626 | APPROVED |
| 2005-01-12 | Nt5c2_predicted | 5'-nucleotidase, cytosolic II (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |
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| More on Nt5c2 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 2323387 |
| Created: | 2010-05-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2019-11-27 |
| Status: | ACTIVE |
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.
