PRSTS330_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: PRSTS330_H (Prostate tumor susceptibility QTL 330 (human)) Homo sapiens

Symbol: PRSTS330_H
Name: Prostate tumor susceptibility QTL 330 (human)
RGD ID: 2299958
Trait: Prostate tumor susceptibility
LOD Score: 1.02
P Value: 0.0151
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381534,790,230 - 60,790,230RGD_MAPPER_PIPELINEGRCh38
GRCh371531,260,818 - 35,082,431RGD_MAPPER_PIPELINEGRCh37
Build 36153,048,110 - 29,048,110RGDNCBI36
Population Stats: Washington University School of Medicine Study
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PRSTS330_HHumanProstatic Neoplasms susceptibilityIAGP 2298844 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PRSTS330_HHumanProstate cancer susceptibilityIDA 2298844 RGD 

#
Reference Title
Reference Citation
1. Model-free linkage analysis with covariates confirms linkage of prostate cancer to chromosomes 1 and 4. Goddard KA, etal., Am J Hum Genet. 2001 May;68(5):1197-206. Epub 2001 Apr 13.

Related QTL Description Reference
PRSTS296_H maps to same region RGD:2298844
PRSTS306_H maps to same region RGD:2298844
PRSTS285_H maps to same region RGD:2298844



1 to 20 of 1684 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
155791572LOC128092252uncharacterized LOC128092252155064880250686717Human
735508SORDsorbitol dehydrogenase154502319545077185Human
1318367TGM5transglutaminase 5154323259043266928Human
736877LIPClipase C, hepatic type155843199158569844Human
735892B2Mbeta-2-microglobulin154471151744718145Human
734140EHD4EH domain containing 4154189593341972557Human
329955976LOC128966560uncharacterized LOC128966560154822717048230432Human
1346093PYGO1pygopus family PHD finger 1155553888455588971Human
737562GPR176G protein-coupled receptor 176153979900839920266Human
1313112FOXB1forkhead box B1156000431160007444Human
1313258EPB42erythrocyte membrane protein band 4.2154319722743225737Human
1315740FSIP1fibrous sheath interacting protein 1153959744039782841Human
735847ADAM10ADAM metallopeptidase domain 10155858880958749707Human
1314717AQRaquarius intron-binding spliceosomal factor153485178234969742Human
732409PLCB2phospholipase C beta 2154028425640307935Human
731453MYO5Amyosin VA155230728352529050Human
736404TYRO3TYRO3 protein tyrosine kinase154155921241583589Human
1320640MYO5Cmyosin VC155219232252295804Human
1343503SLC30A4solute carrier family 30 member 4154547960645522755Human
1323434ZNF280Dzinc finger protein 280D155663017656733509Human

1 to 20 of 1684 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match

Flank 1: (ACTC1)
Human AssemblyChrPosition (strand)Source
GRCh381534,790,230 - 34,795,549 (-)NCBI
GRCh38.p14 Ensembl1534,790,107 - 34,795,589 (-)Ensembl
GRCh371535,082,431 - 35,087,750 (-)NCBI
Build 361532,867,589 - 32,875,219 (-)NCBI
Build 341532,869,723 - 32,875,153NCBI
Celera1511,839,644 - 11,847,274 (-)NCBI
Cytogenetic Map15q14ENTREZGENE
HuRef1511,925,790 - 11,933,402 (-)NCBI
CHM1_11535,198,283 - 35,205,917 (-)NCBI
T2T-CHM13v2.01532,595,427 - 32,600,746 (-)NCBI
Flank 2: (D15S165)
Human AssemblyChrPosition (strand)Source
GRCh371531,260,619 - 31,260,813UniSTS
GRCh371531,260,623 - 31,260,818UniSTS
Build 361529,047,915 - 29,048,110RGD
Celera158,986,083 - 8,986,277UniSTS
Celera158,986,087 - 8,986,282RGD
Cytogenetic Map15q15UniSTS
Cytogenetic Map15q11.2-q13.1UniSTS
Cytogenetic Map15q13.3UniSTS
Cytogenetic Map15q11-q13UniSTS
HuRef158,437,542 - 8,437,739UniSTS
HuRef158,437,538 - 8,437,734UniSTS
Marshfield Genetic Map1520.24UniSTS
Marshfield Genetic Map1520.24RGD
Genethon Genetic Map1520.2UniSTS
TNG Radiation Hybrid Map154334.0UniSTS
deCODE Assembly Map1522.64UniSTS
Stanford-G3 RH Map15395.0UniSTS
NCBI RH Map1546.8UniSTS
GeneMap99-G3 RH Map15395.0UniSTS


1 to 10 of 9441 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597205912GWAS1301986_Hsmoking status measurement, Cannabis use, schizophrenia QTL GWAS1301986 (human)1e-09smoking status measurement, Cannabis use, schizophrenia154732418347324184Human
597517213GWAS1613287_Hremnant cholesterol measurement QTL GWAS1613287 (human)2e-27remnant cholesterol measurement155843364058433641Human
597517212GWAS1613286_Hremnant cholesterol measurement QTL GWAS1613286 (human)2e-54remnant cholesterol measurement155838652158386522Human
406968384GWAS617360_Hcholesteryl ester measurement, intermediate density lipoprotein measurement QTL GWAS617360 (human)9e-44cholesteryl ester measurement, intermediate density lipoprotein measurement155843454558434546Human
406968386GWAS617362_Hlipid measurement, intermediate density lipoprotein measurement QTL GWAS617362 (human)3e-109lipid measurement, intermediate density lipoprotein measurement155843454558434546Human
597271455GWAS1367529_HX-12063 measurement QTL GWAS1367529 (human)2e-08X-12063 measurement154009519340095194Human
597517211GWAS1613285_Hremnant cholesterol measurement QTL GWAS1613285 (human)3e-10remnant cholesterol measurement155827971158279712Human
597484436GWAS1580510_Htotal cortical area measurement QTL GWAS1580510 (human)3e-22cerebral cortex morphology trait (VT:0000788)153935569339355694Human
597484432GWAS1580506_Htotal cortical area measurement QTL GWAS1580506 (human)5e-89cerebral cortex morphology trait (VT:0000788)153934292339342924Human
597517201GWAS1613275_Hapolipoprotein A 1 measurement QTL GWAS1613275 (human)5e-142apolipoprotein A 1 measurementblood apolipoprotein AI level (CMO:0000520)155838875558388756Human

1 to 10 of 9441 rows


Note Type Note Reference
qtl_general Adding male-to-male transmission as covariate significantly increased LOD score to 2.42, P=0.011 for covariate 2298844
qtl_map 15p, 8 cM 2298844
qtl_population Washington University School of Medicine Study 2298844
qtl_population_details 564 men from 254 families, 326 affected sib-pairs, all families with at least 2 affected brothers, and all subjects with Gleason scores 2298844
qtl_statistics_details Software used: GENIBD program from the S.A.G.E., release 4.0 beta; multipoint model-free Z score, affected sib-pair analysis 2298844