GWAS1479634_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1479634_H (triglyceride change measurement, response to simvastatin, response to fenofibrate QTL GWAS1479634 (human)) Homo sapiens

Symbol: GWAS1479634_H
Name: triglyceride change measurement, response to simvastatin, response to fenofibrate QTL GWAS1479634 (human)
RGD ID: 597383560
Trait: triglyceride change measurement, response to simvastatin, response to fenofibrate
Measurement Type: blood triglyceride level   (CMO:0000118)    
LOD Score: Not Available
P Value: 5.0E-7
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381538,887,084 - 38,887,085RGD_MAPPER_PIPELINEGRCh38
GRCh371539,179,285 - 39,179,286RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1479634_HHumanresponse to fenofibrate  IAGPrs11636249405850206 GWAS_CATALOGPMID:28736931
GWAS1479634_HHumanresponse to simvastatin  IAGPrs11636249405850206 GWAS_CATALOGPMID:28736931


Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1479634_HHumanblood triglyceride level  IAGPrs11636249405850206 GWAS_CATALOGPMID:28736931

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1479634_HHumantriglyceride change measurement  IAGPrs11636249405850206 GWAS_CATALOGPMID:28736931

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
38627269LOC105370777uncharacterized LOC105370777153886480639421060Human


Peak: (rs11636249)
Human AssemblyChrPosition (strand)Source
GRCh381538,887,084 - 38,887,085RGD_MAPPER_PIPELINE


1 to 9 of 9 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
597383560GWAS1479634_Htriglyceride change measurement, response to simvastatin, response to fenofibrate QTL GWAS1479634 (human)0.0000005triglyceride change measurement, response to simvastatin, response to fenofibrateblood triglyceride level (CMO:0000118)153888708438887085Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human

1 to 9 of 9 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1479634_H GCST004766 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes 781 European ancestry individuals, 138 African American ancestry individuals, 345 unknown ancestry individuals ? NR 5E-7 6.302 rs11636249 0.153 triglyceride change measurement (EFO:0007681)
response to simvastatin (GO:1903491)
response to fenofibrate (GO:1901557)
 PMID:28736931
Database
Acc Id
Source(s)
GWAS Catalog GCST004766 GWAS Catalog

Note Type Note Reference