GWAS1490955_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1490955_H (high density lipoprotein cholesterol measurement QTL GWAS1490955 (human)) Homo sapiens

Symbol: GWAS1490955_H
Name: high density lipoprotein cholesterol measurement QTL GWAS1490955 (human)
RGD ID: 597394881
Trait: high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 1.0E-65
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,391,167 - 58,391,168RGD_MAPPER_PIPELINEGRCh38
GRCh371558,683,366 - 58,683,367RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1490955_HHumanblood high density lipoprotein cholesterol level  IAGPrs1532085405850206 GWAS_CATALOGPMID:30926973

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1490955_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs1532085405850206 GWAS_CATALOGPMID:30926973

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs1532085)
Human AssemblyChrPosition (strand)Source
GRCh381558,391,167 - 58,391,168RGD_MAPPER_PIPELINE


1 to 10 of 176 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597377947GWAS1474021_Hhigh density lipoprotein cholesterol measurement QTL GWAS1474021 (human)1e-35high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155839116758391168Human
597393563GWAS1489637_Hserum metabolite measurement QTL GWAS1489637 (human)6e-19serum metabolite measurement155839116758391168Human
597427870GWAS1523944_Hphosphatidylcholine measurement QTL GWAS1523944 (human)5e-75phosphatidylcholine measurement155839116758391168Human
597393560GWAS1489634_Hserum metabolite measurement QTL GWAS1489634 (human)3e-29serum metabolite measurement155839116758391168Human
597485464GWAS1581538_Hphosphatidylethanolamine measurement QTL GWAS1581538 (human)1e-47phosphatidylethanolamine measurement155839116758391168Human
597392287GWAS1488361_Hserum metabolite measurement QTL GWAS1488361 (human)1e-13serum metabolite measurement155839116758391168Human
597391005GWAS1487079_Htriglyceride measurement QTL GWAS1487079 (human)3e-51triglyceride measurementblood triglyceride level (CMO:0000118)155839116758391168Human
597393554GWAS1489628_Hserum metabolite measurement QTL GWAS1489628 (human)1e-36phosphatidylethanolamine measurement155839116758391168Human
597489046GWAS1585120_Hcholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS1585120 (human)3e-244cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155839116758391168Human
597377937GWAS1474011_Htotal cholesterol measurement QTL GWAS1474011 (human)0.0000004total cholesterol measurementblood total cholesterol level (CMO:0000051)155839116758391168Human

1 to 10 of 176 rows


1 to 20 of 217 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1490955_H GCST008685 HDL cholesterol levels up to 23,761 African ancestry individuals, 13,171 Asian ancestry individuals, up to 90,272 European ancestry individuals, 6,620 Hispanic individuals A 0.4113 1E-65 65 rs1532085 0.0185 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30926973
GWAS1113081_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals A 0.378 2E-20 19.699 rs1532085 0.044 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1113082_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals A 0.49 7E-10 9.155 rs1532085 0.097 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1113585_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 2E-42 41.699 rs1532085 0.06431696 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1726183_H GCST009367 HDL cholesterol levels x short total sleep time interaction (2df test) 3,007 African American short sleepers, 369 Chinese ancestry short sleepers, 114 Asian ancestry short sleepers, at least 8,474 European ancestry short sleepers, 1,082 Hispanic/Latino short sleepers, up to 11,901 African American controls, 1,444 Chinese ancestry controls, 452 Asian ancestry controls, at least 31,567 European ancestry controls, 4,047 Hispanic/Latino controls ? NR 2E-83 82.699 rs1532085 0.01819 sleep duration trait (OBA:2040171)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:31719535
GWAS1668993_H GCST90480669 red blood cell count (RBC, mean, inv-norm transformed) 114,768 African American or Afro-Caribbean individuals, 55,750 Hispanic or Latin American individuals, 5,943 East Asian ancestry individuals, 405,366 European ancestry individuals A 0.4065 9E-13 12.046 rs1532085 0.01925 erythrocyte count (EFO:0004305)
 PMID:39024449
GWAS1748630_H GCST90093051 Triglycerides to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals A 0.384918 2E-155 154.699 rs1532085 0.113642 triglycerides:total lipids ratio (EFO:0020947)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1755813_H GCST90302149 Triglycerides to total lipids ratio in very large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals A 0.4111 6E-61 60.222 rs1532085 0.0726 triglycerides:total lipids ratio (EFO:0020947)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1757574_H GCST90093041 Cholesterol to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals A 0.384918 7E-113 112.155 rs1532085 0.0960421 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1757764_H GCST90093043 Cholesteryl esters to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals A 0.384918 8E-81 80.097 rs1532085 0.0814245 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1758984_H GCST90093045 Free cholesterol to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals A 0.384918 2E-144 143.699 rs1532085 0.108126 free cholesterol:total lipids ratio (EFO:0020945)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1760066_H GCST90092869 Cholesterol to total lipids ratio in large VLDL 115,071 European ancestry individuals A 0.386036 2E-168 167.699 rs1532085 0.114602 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1766741_H GCST90239613 Very low density lipoprotein cholesterol levels 75,388 Taiwanese ancestry individuals ? NR 2E-78 77.699 rs1532085 1.37233 blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:36329257
GWAS1451509_H GCST001765 Red blood cell traits 62,553 European ancestry individuals, 9,308 South Asian ancestry individuals G 0.59 7E-11 10.155 rs1532085 0.034 hemoglobin measurement (EFO:0004509)
 PMID:23222517
GWAS1452217_H GCST000533 Lipid metabolism phenotypes Up to 17,296 European ancestry female individuals ? NR 4E-16 15.398 rs1532085 0.112 lipid measurement (EFO:0004529)
 PMID:19936222
GWAS1452478_H GCST000533 Lipid metabolism phenotypes Up to 17,296 European ancestry female individuals ? NR 1E-19 19 rs1532085 0.107 lipid measurement (EFO:0004529)
 PMID:19936222
GWAS1452479_H GCST000533 Lipid metabolism phenotypes Up to 17,296 European ancestry female individuals ? NR 9E-15 14.046 rs1532085 1.421 lipid measurement (EFO:0004529)
 PMID:19936222
GWAS1452734_H GCST001639 Metabolite levels 6,608 European ancestry individuals ? 0.44 9E-104 103.046 rs1532085 N/A coronary artery calcification (EFO:0004723)
 PMID:22916037
GWAS1459212_H GCST004232 HDL cholesterol levels 34,930 East Asian ancestry individuals, 187,167 European ancestry individuals A 0.367 1E-213 213 rs1532085 0.107 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:28334899
GWAS1461014_H GCST008702 Triglyceride levels up to 23,508 African ancestry individuals, 4,649 Asian ancestry individuals, up to 77,047 European ancestry individuals, 6,705 Hispanic individuals A 0.4038 9E-8 7.046 rs1532085 0.013 triglyceride measurement (EFO:0004530)
 PMID:30926973
1 to 20 of 217 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST008685 GWAS Catalog

Note Type Note Reference