GWAS617115_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS617115_H (reticulocyte count QTL GWAS617115 (human)) Homo sapiens

Symbol: GWAS617115_H
Name: reticulocyte count QTL GWAS617115 (human)
RGD ID: 406968139
Trait: reticulocyte quantity   (VT:0003135)    
Measurement Type: total reticulocyte count   (CMO:0003020)    
LOD Score: Not Available
P Value: 1.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381540,014,133 - 40,014,134RGD_MAPPER_PIPELINEGRCh38
GRCh371540,306,334 - 40,306,335RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS617115_HHumantotal reticulocyte count  IAGPrs12050884405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS617115_HHumanreticulocyte quantity  IAGPrs12050884405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS617115_HHumanreticulocyte count  IAGPrs12050884405850206 GWAS_CATALOGPMID:27863252

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1322904EIF2AK4eukaryotic translation initiation factor 2 alpha kinase 4153993411540035591Human


Peak: (rs12050884)
Human AssemblyChrPosition (strand)Source
GRCh381540,014,133 - 40,014,134RGD_MAPPER_PIPELINE


1 to 10 of 28 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
406982084GWAS631060_Hreticulocyte count QTL GWAS631060 (human)4e-11reticulocyte quantity (VT:0003135)total reticulocyte count (CMO:0003020)154001413340014134Human
407084612GWAS733588_Hobsolete_red blood cell distribution width QTL GWAS733588 (human)1e-24obsolete_red blood cell distribution width154001413340014134Human
407382848GWAS1031824_Hobsolete_red blood cell distribution width QTL GWAS1031824 (human)6e-47obsolete_red blood cell distribution width154001413340014134Human
406968139GWAS617115_Hreticulocyte count QTL GWAS617115 (human)1e-10reticulocyte quantity (VT:0003135)total reticulocyte count (CMO:0003020)154001413340014134Human
597052184GWAS1148258_Herythrocyte count QTL GWAS1148258 (human)1e-23erythrocyte countred blood cell count (CMO:0000025)154001413340014134Human
596950874GWAS1070393_HRed cell distribution width QTL GWAS1070393 (human)6e-47Red cell distribution width154001413340014134Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
597108291GWAS1204365_Herythrocyte count QTL GWAS1204365 (human)2e-17erythrocyte countred blood cell count (CMO:0000025)154001413340014134Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
596956301GWAS1075820_HRed cell distribution width QTL GWAS1075820 (human)8e-40Red cell distribution width154001413340014134Human

1 to 10 of 28 rows


1 to 11 of 11 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS617115_H GCST004619 Reticulocyte fraction of red cells 170,690 European ancestry individuals A 0.2067 1E-10 10 rs12050884 0.02857949 reticulocyte count (EFO:0007986)
 PMID:27863252
GWAS1069161_H GCST004621 Red cell distribution width 171,529 European ancestry individuals A 0.2067 3E-16 15.523 rs12050884 0.03570059 Red cell distribution width (EFO:0009188)
 PMID:27863252
GWAS1146227_H GCST007074 Red cell distribution width approximately 445,000 European ancestry individuals ? NR 8E-40 39.097 rs12050884 N/A Red cell distribution width (EFO:0009188)
 PMID:30595370
GWAS1148258_H GCST007069 Red blood cell count approximately 445,000 European ancestry individuals ? NR 1E-23 23 rs12050884 N/A erythrocyte count (EFO:0004305)
 PMID:30595370
GWAS622723_H GCST004612 High light scatter reticulocyte percentage of red cells 170,763 European ancestry individuals A 0.2068 1E-9 9 rs12050884 0.02700095 reticulocyte count (EFO:0007986)
 PMID:27863252
GWAS631060_H GCST90002385 High light scatter reticulocyte count 408,112 British individuals A 0.207354 4E-11 10.398 rs12050884 0.018200638 reticulocyte count (EFO:0007986)
 PMID:32888494
GWAS639657_H GCST90002386 High light scatter reticulocyte percentage of red cells 408,112 British individuals A 0.207353 1E-15 15 rs12050884 0.021990504 reticulocyte measurement (EFO:0010700)
 PMID:32888494
GWAS1176171_H GCST90002372 Red cell distribution width 563,352 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals C 0.789263 6E-47 46.222 rs12050884 N/A Red cell distribution width (EFO:0009188)
 PMID:32888493
GWAS1184046_H GCST90002369 Red cell distribution width 531,774 European ancestry individuals C 0.794121 2E-50 49.699 rs12050884 0.034674 Red cell distribution width (EFO:0009188)
 PMID:32888493
GWAS1204365_H GCST90002403 Red blood cell count 408,112 British individuals A 0.207271 2E-17 16.699 rs12050884 0.02315594 erythrocyte count (EFO:0004305)
 PMID:32888494
GWAS1210489_H GCST90002404 Red cell distribution width 408,112 British individuals A 0.207253 1E-24 24 rs12050884 0.029973445 Red cell distribution width (EFO:0009188)
 PMID:32888494
1 to 11 of 11 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST004619 GWAS Catalog

Note Type Note Reference