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Gene: DUOXA1 (dual oxidase maturation factor 1) Homo sapiens
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Symbol: DUOXA1
Name: dual oxidase maturation factor 1
RGD ID: 1602196
Description: Exhibits enzyme binding activity. Involved in cellular protein localization and positive regulation of hydrogen peroxide biosynthetic process. Localizes to cell leading edge; endoplasmic reticulum; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dual oxidase activator 1; dual oxidase maturation factor 1 alpha; dual oxidase maturation factor 1 beta; dual oxidase maturation factor 1 delta; dual oxidase maturation factor 1 gamma; FLJ32334; homolog of Drosophila Numb-interacting protein; mol; NIP; numb-interacting protein; NUMBIP
Orthologs:
Mus musculus (house mouse) : Duoxa1 (dual oxidase maturation factor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Duoxa1 (dual oxidase maturation factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Duoxa1 (dual oxidase maturation factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DUOXA1 (dual oxidase maturation factor 1)
Canis lupus familiaris (dog) : DUOXA1 (dual oxidase maturation factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Duoxa1 (dual oxidase maturation factor 1)
Sus scrofa (pig) : DUOXA1 (dual oxidase maturation factor 1)
Chlorocebus sabaeus (African green monkey) : DUOXA1 (dual oxidase maturation factor 1)
Heterocephalus glaber (naked mole-rat) : Duoxa1 (dual oxidase maturation factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1545,117,367 - 45,129,938 (-)EnsemblGRCh38hg38GRCh38
GRCh381545,117,366 - 45,129,938 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371545,409,564 - 45,422,075 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361543,196,977 - 43,209,349 (-)NCBINCBI36hg18NCBI36
Celera1522,301,120 - 22,313,493 (-)NCBI
Cytogenetic Map15q21.1NCBI
HuRef1522,233,776 - 22,246,288 (-)NCBIHuRef
CHM1_11545,527,897 - 45,540,408 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on DUOXA1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1602196
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.