GWAS1546546_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1546546_H (BMI-adjusted waist-hip ratio QTL GWAS1546546 (human)) Homo sapiens

Symbol: GWAS1546546_H
Name: BMI-adjusted waist-hip ratio QTL GWAS1546546 (human)
RGD ID: 597450472
Trait: body size trait   (VT:0100005)    
LOD Score: Not Available
P Value: 5.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381551,242,350 - 51,242,351RGD_MAPPER_PIPELINEGRCh38
GRCh371551,534,547 - 51,534,548RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1546546_HHumanbody size trait  IAGPrs727479405850206 GWAS_CATALOGPMID:34021172

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1546546_HHumanBMI-adjusted waist-hip ratio  IAGPrs727479405850206 GWAS_CATALOGPMID:34021172

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
12791128MIR4713HGMIR4713 host gene155103748851293912Human
11084865PIRC66piwi-interacting RNA cluster 66155103758451322397Human
1606587CYP19A1cytochrome P450 family 19 subfamily A member 1155120805751338596Human


Peak: (rs727479)
Human AssemblyChrPosition (strand)Source
GRCh381551,242,350 - 51,242,351RGD_MAPPER_PIPELINE


1 to 10 of 11 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
597450472GWAS1546546_HBMI-adjusted waist-hip ratio QTL GWAS1546546 (human)5e-11body size trait (VT:0100005)155124235051242351Human
597439608GWAS1535682_Hestrone measurement QTL GWAS1535682 (human)2e-22estrone measurement155124235051242351Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
597421454GWAS1517528_Hestradiol measurement, testosterone measurement QTL GWAS1517528 (human)4e-21estradiol measurement, testosterone measurementserum testosterone level (CMO:0000568)155124235051242351Human
597421453GWAS1517527_Hestradiol measurement, testosterone measurement QTL GWAS1517527 (human)2e-09estradiol measurement, testosterone measurementserum testosterone level (CMO:0000568)155124235051242351Human
597422626GWAS1518700_HBMI-adjusted waist-hip ratio QTL GWAS1518700 (human)7e-11body size trait (VT:0100005)155124235051242351Human
597439606GWAS1535680_Hestradiol measurement QTL GWAS1535680 (human)8e-30estradiol measurementblood estradiol level (CMO:0000513)155124235051242351Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human

1 to 10 of 11 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1546546_H GCST012228 Waist-hip index 186,825 British ancestry men C NR 5E-11 10.302 rs727479 0.021577 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:34021172
GWAS1466767_H GCST001553 Estradiol levels 1,583 European ancestry female individuals C 0.34 5E-7 6.302 rs727479 0.107 estradiol measurement (EFO:0004697)
 PMID:22675492
GWAS1517527_H GCST90094683 Testosterone to estradiol ratio 5,696 individuals A NR 2E-9 8.699 rs727479 0.115024 estradiol measurement (EFO:0004697)
testosterone measurement (EFO:0004908)
 PMID:34822396
GWAS1517528_H GCST90094684 Testosterone to estradiol ratio 3,413 men A NR 4E-21 20.398 rs727479 0.141224 estradiol measurement (EFO:0004697)
testosterone measurement (EFO:0004908)
 PMID:34822396
GWAS1518700_H GCST012230 Waist-to-hip ratio adjusted for BMI 186,825 British ancestry men C NR 7E-11 10.155 rs727479 0.0213524 BMI-adjusted waist-hip ratio (EFO:0007788)
 PMID:34021172
GWAS1535680_H GCST005828 Estradiol levels 11,097 European ancestry men A 0.63 8E-30 29.097 rs727479 1.39 estradiol measurement (EFO:0004697)
 PMID:29325096
GWAS1535682_H GCST005827 Estrone levels 7,570 European ancestry men A 0.65 2E-22 21.699 rs727479 2.09 estrone measurement (EFO:0007970)
 PMID:29325096
Database
Acc Id
Source(s)
GWAS Catalog GCST012228 GWAS Catalog

Note Type Note Reference