GWAS1499635_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1499635_H (high density lipoprotein cholesterol measurement QTL GWAS1499635 (human)) Homo sapiens

Symbol: GWAS1499635_H
Name: high density lipoprotein cholesterol measurement QTL GWAS1499635 (human)
RGD ID: 597403561
Trait: high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 6E-87
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,387,979 - 58,387,980RGD_MAPPER_PIPELINEGRCh38
GRCh371558,680,178 - 58,680,179RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1499635_HHumanblood high density lipoprotein cholesterol level  IAGPrs261291405850206 GWAS_CATALOGPMID:25961943

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1499635_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs261291405850206 GWAS_CATALOGPMID:25961943

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs261291)
Human AssemblyChrPosition (strand)Source
GRCh381558,387,979 - 58,387,980RGD_MAPPER_PIPELINE


1 to 10 of 78 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597413529GWAS1509603_Hvitamin D measurement QTL GWAS1509603 (human)3e-28vitamin D measurement155838797958387980Human
597457048GWAS1553122_Htotal cholesterol in IDL QTL GWAS1553122 (human)2e-75total cholesterol in IDL155838797958387980Human
597458587GWAS1554661_Hfree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS1554661 (human)2e-88free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155838797958387980Human
597456150GWAS1552224_Hcholesterol esters in large HDL measurement QTL GWAS1552224 (human)1e-319cholesterol esters in large HDL measurement155838797958387980Human
597364497GWAS1460571_HAlzheimer disease, high density lipoprotein cholesterol measurement QTL GWAS1460571 (human)4e-84Alzheimer disease, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155838797958387980Human
597442833GWAS1538907_Hhigh density lipoprotein cholesterol measurement QTL GWAS1538907 (human)1e-40high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155838797958387980Human
597463187GWAS1559261_Htriglyceride measurement QTL GWAS1559261 (human)3e-26triglyceride measurementblood triglyceride level (CMO:0000118)155838797958387980Human
597457678GWAS1553752_Hphospholipids in medium HDL measurement QTL GWAS1553752 (human)1e-77blood HDL phospholipid amount (VT:0010504)155838797958387980Human
597529870GWAS1625944_H1-palmitoyl-GPE (16:0) measurement QTL GWAS1625944 (human)1e-551-palmitoyl-GPE (16:0) measurement155838797958387980Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human

1 to 10 of 78 rows


1 to 20 of 95 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1499635_H GCST002899 HDL cholesterol up to 62,166 European ancestry individuals C 0.37 6E-87 86.222 rs261291 0.122 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:25961943
GWAS1113078_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals T 0.65 6E-21 20.222 rs261291 0.045 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1113079_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals T 0.548 3E-9 8.523 rs261291 0.095 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1113080_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals T NR 1E-28 28 rs261291 0.048 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1635317_H GCST90479633 high density lipoprotein cholesterol (HDLC, minimm, inv-norm transformed) 113,085 African American or Afro-Caribbean individuals, 54,914 Hispanic or Latin American individuals, 6,005 East Asian ancestry individuals, 404,121 European ancestry individuals T 0.6339 3E-312 311.523 rs261291 0.1191 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:39024449
GWAS1725863_H GCST009368 HDL cholesterol levels x long total sleep time interaction (2df test) 2,933 African American long sleepers, 364 Chinese ancestry long sleepers, 112 Asian ancestry long sleepers, up to 7,870 European ancestry long sleepers, 1,038 Hispanic/Latino long sleepers, up to 11,975 African American controls, 1,449 Chinese ancestry controls, 454 Asian ancestry controls, at least 32,171 European ancestry controls, 4,091 Hispanic/Latino controls ? NR 4E-97 96.398 rs261291 0.02067 sleep duration trait (OBA:2040171)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:31719535
GWAS1750210_H GCST90093049 Phospholipids to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals T 0.644918 9E-197 196.046 rs261291 0.129381 phospholipids:total lipids ratio (EFO:0020946)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1754516_H GCST90302155 Free cholesterol to total lipids ratio in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6314 3E-33 32.523 rs261291 0.0481 free cholesterol:total lipids ratio (EFO:0020945)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1754631_H GCST90302058 Total cholesterol to total lipids ratio in medium VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6314 5E-283 282.302 rs261291 0.1442 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1754714_H GCST90302060 Cholesteryl esters to total lipids ratio in medium VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6313 3E-160 159.523 rs261291 0.1087 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1754943_H GCST90302141 Cholesteryl esters to total lipids ratio in very large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals T 0.6298 2E-24 23.699 rs261291 0.0453 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1755144_H GCST90302139 Total cholesterol to total lipids ratio in very large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals T 0.6297 2E-49 48.699 rs261291 0.0658 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1755294_H GCST90302165 Cholesteryl esters to total lipids ratio in chylomicrons and extremely large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals T 0.6291 8E-118 117.097 rs261291 0.0996 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:38448586
GWAS1755683_H GCST90302152 Cholesterol esters in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6313 1E-99 99 rs261291 0.085 esterified cholesterol measurement (EFO:0008589)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1756177_H GCST90302066 Phospholipids to total lipids ratio in medium VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6313 2E-197 196.699 rs261291 0.1206 phospholipids:total lipids ratio (EFO:0020946)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1758405_H GCST90302113 Phospholipids to total lipids ratio in small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6312 8E-80 79.097 rs261291 0.0767 phospholipids:total lipids ratio (EFO:0020946)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1759174_H GCST90302105 Total cholesterol to total lipids ratio in small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6312 7E-35 34.155 rs261291 0.0501 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1759942_H GCST90302020 Total cholesterol to total lipids ratio in large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6307 2E-127 126.699 rs261291 0.1014 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1759993_H GCST90302022 Cholesteryl esters to total lipids ratio in large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6308 2E-47 46.699 rs261291 0.0608 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1460571_H GCST007827 Alzheimer's disease or HDL levels (pleiotropy) 54,162 European ancestry cases, 60,812 European ancestry individuals ? NR 4E-84 83.398 rs261291 N/A high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30805717
1 to 20 of 95 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST002899 GWAS Catalog

Note Type Note Reference