GWAS1756177_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1756177_H (phospholipids:total lipids ratio, blood VLDL cholesterol amount QTL GWAS1756177 (human)) Homo sapiens

Symbol: GWAS1756177_H
Name: phospholipids:total lipids ratio, blood VLDL cholesterol amount QTL GWAS1756177 (human)
RGD ID: 598036878
Trait: phospholipids:total lipids ratio, blood VLDL cholesterol amount
LOD Score: Not Available
P Value: 2E-197
Variance: Not Available
Position No map positions available.
Population Stats: Not Available



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1756177_HHumanblood VLDL cholesterol amount  IAGPrs261291405850206 GWAS_CATALOGPMID:38448586
GWAS1756177_HHumanphospholipids:total lipids ratio  IAGPrs261291405850206 GWAS_CATALOGPMID:38448586

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs261291)
Human AssemblyChrPosition (strand)Source
GRCh381558,387,979 - 58,387,980RGD_MAPPER_PIPELINE



1 to 20 of 95 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1756177_H GCST90302066 Phospholipids to total lipids ratio in medium VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6313 2E-197 196.699 rs261291 0.1206 phospholipids:total lipids ratio (EFO:0020946)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1113078_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals T 0.65 6E-21 20.222 rs261291 0.045 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1113079_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals T 0.548 3E-9 8.523 rs261291 0.095 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1113080_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals T NR 1E-28 28 rs261291 0.048 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1635317_H GCST90479633 high density lipoprotein cholesterol (HDLC, minimm, inv-norm transformed) 113,085 African American or Afro-Caribbean individuals, 54,914 Hispanic or Latin American individuals, 6,005 East Asian ancestry individuals, 404,121 European ancestry individuals T 0.6339 3E-312 311.523 rs261291 0.1191 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:39024449
GWAS1725863_H GCST009368 HDL cholesterol levels x long total sleep time interaction (2df test) 2,933 African American long sleepers, 364 Chinese ancestry long sleepers, 112 Asian ancestry long sleepers, up to 7,870 European ancestry long sleepers, 1,038 Hispanic/Latino long sleepers, up to 11,975 African American controls, 1,449 Chinese ancestry controls, 454 Asian ancestry controls, at least 32,171 European ancestry controls, 4,091 Hispanic/Latino controls ? NR 4E-97 96.398 rs261291 0.02067 sleep duration trait (OBA:2040171)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:31719535
GWAS1750210_H GCST90093049 Phospholipids to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals T 0.644918 9E-197 196.046 rs261291 0.129381 phospholipids:total lipids ratio (EFO:0020946)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1754516_H GCST90302155 Free cholesterol to total lipids ratio in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6314 3E-33 32.523 rs261291 0.0481 free cholesterol:total lipids ratio (EFO:0020945)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1754631_H GCST90302058 Total cholesterol to total lipids ratio in medium VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6314 5E-283 282.302 rs261291 0.1442 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1754714_H GCST90302060 Cholesteryl esters to total lipids ratio in medium VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6313 3E-160 159.523 rs261291 0.1087 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1754943_H GCST90302141 Cholesteryl esters to total lipids ratio in very large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals T 0.6298 2E-24 23.699 rs261291 0.0453 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1755144_H GCST90302139 Total cholesterol to total lipids ratio in very large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals T 0.6297 2E-49 48.699 rs261291 0.0658 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1755294_H GCST90302165 Cholesteryl esters to total lipids ratio in chylomicrons and extremely large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals T 0.6291 8E-118 117.097 rs261291 0.0996 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:38448586
GWAS1755683_H GCST90302152 Cholesterol esters in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6313 1E-99 99 rs261291 0.085 esterified cholesterol measurement (EFO:0008589)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1758405_H GCST90302113 Phospholipids to total lipids ratio in small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6312 8E-80 79.097 rs261291 0.0767 phospholipids:total lipids ratio (EFO:0020946)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1759174_H GCST90302105 Total cholesterol to total lipids ratio in small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6312 7E-35 34.155 rs261291 0.0501 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1759942_H GCST90302020 Total cholesterol to total lipids ratio in large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6307 2E-127 126.699 rs261291 0.1014 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1759993_H GCST90302022 Cholesteryl esters to total lipids ratio in large VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6308 2E-47 46.699 rs261291 0.0608 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:38448586
GWAS1460571_H GCST007827 Alzheimer's disease or HDL levels (pleiotropy) 54,162 European ancestry cases, 60,812 European ancestry individuals ? NR 4E-84 83.398 rs261291 N/A high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30805717
GWAS1461777_H GCST90002384 Hemoglobin 408,112 British individuals C 0.356683 2E-17 16.699 rs261291 0.019711692 hemoglobin measurement (EFO:0004509)
 PMID:32888494
1 to 20 of 95 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90302066 GWAS Catalog

Note Type Note Reference