GWAS574275_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS574275_H (apolipoprotein B measurement QTL GWAS574275 (human)) Homo sapiens

Symbol: GWAS574275_H
Name: apolipoprotein B measurement QTL GWAS574275 (human)
RGD ID: 406925299
Trait: apolipoprotein B measurement
Measurement Type: blood apoliprotein B level   (CMO:0000522)    
LOD Score: Not Available
P Value: 5.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381557,220,086 - 57,220,087RGD_MAPPER_PIPELINEGRCh38
GRCh371557,512,284 - 57,512,285RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS574275_HHumanblood apoliprotein B level  IAGPrs72733928405850206Based on the EFO term IDGWAS_CATALOGPMID:32203549

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS574275_HHumanapolipoprotein B measurement  IAGPrs72733928405850206 GWAS_CATALOGPMID:32203549
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
731955TCF12transcription factor 12155691809057291310Human

Position Markers

Peak: (rs72733928)
Human AssemblyChrPosition (strand)Source
GRCh381557,220,086 - 57,220,087RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406925299GWAS574275_Hapolipoprotein B measurement QTL GWAS574275 (human)5e-10apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)155722008657220087Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407336399GWAS985375_Htotal cholesterol measurement QTL GWAS985375 (human)4e-08total cholesterol measurementblood total cholesterol level (CMO:0000051)155722008657220087Human
406919853GWAS568829_Hlow density lipoprotein cholesterol measurement QTL GWAS568829 (human)2e-09low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155722008657220087Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS568829_H GCST010245 LDL cholesterol levels 440,546 European ancestry individuals A 0.939813 2E-9 8.699 rs72733928 0.0263176 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32203549
GWAS574275_H GCST010243 Apolipoprotein B levels 439,214 European ancestry individuals A 0.939816 5E-10 9.302 rs72733928 0.0273302 apolipoprotein B measurement (EFO:0004615)
 PMID:32203549
GWAS985375_H GCST90018974 Total cholesterol levels 344,278 European ancestry individuals, 135,808 East Asian ancestry individuals T NR 4E-8 7.398 rs72733928 0.0246 total cholesterol measurement (EFO:0004574)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST010243 GWAS Catalog

RGD Curation Notes
Note Type Note Reference