GWAS574275_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS574275_H (apolipoprotein B measurement QTL GWAS574275 (human)) Homo sapiens

Symbol: GWAS574275_H
Name: apolipoprotein B measurement QTL GWAS574275 (human)
RGD ID: 406925299
Trait: apolipoprotein B measurement
Measurement Type: blood apoliprotein B level   (CMO:0000522)    
LOD Score: Not Available
P Value: 5.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381557,220,086 - 57,220,087RGD_MAPPER_PIPELINEGRCh38
GRCh371557,512,284 - 57,512,285RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS574275_HHumanblood apoliprotein B level  IAGPrs72733928405850206Based on the EFO term IDGWAS_CATALOGPMID:32203549

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS574275_HHumanapolipoprotein B measurement  IAGPrs72733928405850206 GWAS_CATALOGPMID:32203549

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
731955TCF12transcription factor 12155691809057291310Human


Peak: (rs72733928)
Human AssemblyChrPosition (strand)Source
GRCh381557,220,086 - 57,220,087RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
406925299GWAS574275_Hapolipoprotein B measurement QTL GWAS574275 (human)5e-10apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)155722008657220087Human
597312953GWAS1409027_Htotal cholesterol measurement QTL GWAS1409027 (human)4e-08total cholesterol measurementblood total cholesterol level (CMO:0000051)155722008657220087Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
597034495GWAS1130569_Hlow density lipoprotein cholesterol measurement QTL GWAS1130569 (human)2e-09low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155722008657220087Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS574275_H GCST010243 Apolipoprotein B levels 439,214 European ancestry individuals A 0.939816 5E-10 9.302 rs72733928 0.0273302 apolipoprotein B measurement (EFO:0004615)
 PMID:32203549
GWAS1130569_H GCST010245 LDL cholesterol levels 440,546 European ancestry individuals A 0.939813 2E-9 8.699 rs72733928 0.0263176 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32203549
GWAS1409027_H GCST90018974 Total cholesterol levels 344,278 European ancestry individuals, 135,808 East Asian ancestry individuals T NR 4E-8 7.398 rs72733928 0.0246 total cholesterol measurement (EFO:0004574)
 PMID:34594039
Database
Acc Id
Source(s)
GWAS Catalog GCST010243 GWAS Catalog

Note Type Note Reference