GWAS843432_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS843432_H (total cholesterol measurement QTL GWAS843432 (human)) Homo sapiens

Symbol: GWAS843432_H
Name: total cholesterol measurement QTL GWAS843432 (human)
RGD ID: 407194456
Trait: total cholesterol measurement
LOD Score: Not Available
P Value: 2.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,435,126 - 58,435,127RGD_MAPPER_PIPELINEGRCh38
GRCh371558,727,325 - 58,727,326RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
736877LIPClipase C, hepatic type155843199158569844Human
11084824LIPC-AS1LIPC antisense RNA 1155843490158498735Human


Peak: (rs261332)
Human AssemblyChrPosition (strand)Source
GRCh381558,435,126 - 58,435,127RGD_MAPPER_PIPELINE


1 to 10 of 54 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
596964244GWAS1083763_Htotal cholesterol measurement QTL GWAS1083763 (human)5e-08total cholesterol measurement155843512658435127Human
407225028GWAS874004_Htriglyceride measurement QTL GWAS874004 (human)4e-16triglyceride measurement155843512658435127Human
596972820GWAS1092339_Hcholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage QTL GWAS1092339 (human)1e-58cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage 155843512658435127Human
406954818GWAS603794_Hlow density lipoprotein triglyceride measurement QTL GWAS603794 (human)7e-12low density lipoprotein triglyceride measurement155843512658435127Human
597361432GWAS1457506_Htotal cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement QTL GWAS1457506 (human)4e-42total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843512658435127Human
596964752GWAS1084271_Hfree cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS1084271 (human)2e-13free cholesterol measurement, low density lipoprotein cholesterol measurement155843512658435127Human
597452440GWAS1548514_Hlow density lipoprotein triglyceride measurement QTL GWAS1548514 (human)7e-12low density lipoprotein triglyceride measurementblood low density lipoprotein triglyceride level (CMO:0002687)155843512658435127Human
596964243GWAS1083762_Hhigh density lipoprotein cholesterol measurement QTL GWAS1083762 (human)9e-21high density lipoprotein cholesterol measurement155843512658435127Human
407167560GWAS816536_Htotal cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement QTL GWAS816536 (human)4e-42total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement155843512658435127Human
596970905GWAS1090424_Htotal cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer QTL GWAS1090424 (human)2e-35total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer155843512658435127Human

1 to 10 of 54 rows


1 to 20 of 27 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1738498_H GCST90091641 Fasting triglycerides levels in very small VLDL null G 0.79840448 5E-8 7.302 rs261332 0.140891 triglyceride measurement (EFO:0004530)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:34610981
GWAS1457506_H GCST004046 Age-related disease endophenotypes 9,618 European ancestry individuals ? NR 4E-42 41.398 rs261332 N/A total cholesterol measurement (EFO:0004574)
diastolic blood pressure (EFO:0006336)
triglyceride measurement (EFO:0004530)
systolic blood pressure (EFO:0006335)
More... 		PMID:27790247
GWAS1457575_H GCST004045 Age-related diseases, mortality and associated endophenotypes 9,618 European ancestry individuals ? NR 2E-35 34.699 rs261332 N/A total cholesterol measurement (EFO:0004574)
hematocrit (EFO:0004348)
stroke (EFO:0000712)
ventricular rate measurement (EFO:0007928)
More... 		PMID:27790247
GWAS1457746_H GCST004615 Hemoglobin concentration 172,925 European ancestry individuals G 0.792 7E-9 8.155 rs261332 0.02541862 hemoglobin measurement (EFO:0004509)
 PMID:27863252
GWAS1778637_H GCST90092916 Cholesterol levels in medium VLDL 115,082 European ancestry individuals A 0.209008 1E-16 16 rs261332 0.042031 total cholesterol measurement (EFO:0004574)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1778810_H GCST90092918 Cholesteryl ester levels in medium VLDL 115,082 European ancestry individuals A 0.209008 2E-16 15.699 rs261332 0.0414943 cholesteryl ester measurement (EFO:0010351)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1509951_H GCST005776 High density lipoprotein cholesterol levels up to 33,431 European ancestry individuals T 0.1955 9E-21 20.046 rs261332 2.5879784 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29615537
GWAS1509954_H GCST005781 Total cholesterol levels up to 33,431 European ancestry individuals T 0.1955 5E-8 7.302 rs261332 0.96994877 total cholesterol measurement (EFO:0004574)
 PMID:29615537
GWAS1521412_H GCST90060690 Phosphatidylethanolamine(36:4)_[M+H]1+ levels 5,662 Pakistani ancestry individuals G NR 7E-13 12.155 rs261332 0.1872 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
None Available GCST90060689 Phosphatidylethanolamine(36:4)_[M-H]1- levels 5,662 Pakistani ancestry individuals T NR 7E-13 12.155 rs261332 0.0493 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
None Available GCST90060696 Phosphatidylcholine(33:2)_[M+H]1+/Phosphatidylethanolamine(36:2)_[M+H]1+/Phosphatidate(38:3)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals A NR 7E-13 12.155 rs261332 0.1867 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
None Available GCST90060790 Phosphatidylcholine(37:6)_[M+H]1+/Phosphatidylethanolamine(40:6)_[M+H]1+/Phosphatidate(42:7)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals G NR 7E-13 12.155 rs261332 0.187 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
None Available GCST90060665 Phosphatidylethanolamine(34:2)_[M+H]1+ levels 5,662 Pakistani ancestry individuals C NR 7E-13 12.155 rs261332 0.0491 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
None Available GCST90060692 Phosphatidylcholine(33:3)_[M+H]1+/Phosphatidylethanolamine(36:3)_[M+H]1+/Phosphatidate(38:4)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals C NR 7E-13 12.155 rs261332 0.1874 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
None Available GCST90060777 Phosphatidylethanolamine(40:7)_[M-H]1- levels 5,662 Pakistani ancestry individuals T NR 7E-13 12.155 rs261332 0.0851 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
None Available GCST90060733 Phosphatidylethanolamine(38:5)_[M-H]1- levels 5,662 Pakistani ancestry individuals G NR 7E-13 12.155 rs261332 0.0802 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
None Available GCST90060738 Phosphatidylcholine(35:4)_[M+H]1+/Phosphatidylethanolamine(38:4)_[M+H]1+/Phosphatidate(40:5)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals G NR 7E-13 12.155 rs261332 0.0574 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
GWAS1545866_H GCST90092860 Free cholesterol levels in large LDL 115,082 European ancestry individuals A 0.209008 2E-13 12.699 rs261332 0.0366397 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS1547827_H GCST90091673 Postprandial triglycerides levels in IDL null G 0.798003912 2E-22 21.699 rs261332 0.260961 triglyceride measurement (EFO:0004530)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:34610981
GWAS1548514_H GCST90091743 Postprandial triglycerides levels in small LDL null G 0.797935358 7E-12 11.155 rs261332 0.184467 low density lipoprotein triglyceride measurement (EFO:0009946)
 PMID:34610981
1 to 20 of 27 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90010363 GWAS Catalog

Note Type Note Reference