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References
References - curated
Region Genes in Region
RGD ID | Symbol | Name | Chr | Start | Stop | Species | 736877 | LIPC | lipase C, hepatic type | 15 | 58431991 | 58569844 | Human | 11084824 | LIPC-AS1 | LIPC antisense RNA 1 | 15 | 58434901 | 58498735 | Human | |
Position Markers
Peak: (rs261332) |
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QTLs in Region (GRCh38)
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Additional Information
GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog | ![]() |
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The highlighted row represents the current QTL |
QTL | GWAS Catalog Study | Disease Trait | Study Size | Risk Allele | Risk Allele Frequency | P Value | P Value MLOG | Peak Marker | Reported Odds Ratio or Beta-coefficient | Ontology Accession | PubMed |
GWAS1457506_H | GCST004046 | Age-related disease endophenotypes | 9,618 European ancestry individuals | ? | NR | 4E-42 | 41.398 | rs261332 | N/A | total cholesterol measurement (EFO:0004574) diastolic blood pressure (EFO:0006336) triglyceride measurement (EFO:0004530) systolic blood pressure (EFO:0006335) More... |
PMID:27790247 |
GWAS1457575_H | GCST004045 | Age-related diseases, mortality and associated endophenotypes | 9,618 European ancestry individuals | ? | NR | 2E-35 | 34.699 | rs261332 | N/A | total cholesterol measurement (EFO:0004574) hematocrit (EFO:0004348) stroke (EFO:0000712) ventricular rate measurement (EFO:0007928) More... |
PMID:27790247 |
GWAS1457746_H | GCST004615 | Hemoglobin concentration | 172,925 European ancestry individuals | G | 0.792 | 7E-9 | 8.155 | rs261332 | 0.02541862 | hemoglobin measurement (EFO:0004509) |
PMID:27863252 |
GWAS1509951_H | GCST005776 | High density lipoprotein cholesterol levels | up to 33,431 European ancestry individuals | T | 0.1955 | 9E-21 | 20.046 | rs261332 | 2.5879784 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:29615537 |
GWAS1509954_H | GCST005781 | Total cholesterol levels | up to 33,431 European ancestry individuals | T | 0.1955 | 5E-8 | 7.302 | rs261332 | 0.96994877 | total cholesterol measurement (EFO:0004574) |
PMID:29615537 |
GWAS1521412_H | GCST90060690 | Phosphatidylethanolamine(36:4)_[M+H]1+ levels | 5,662 Pakistani ancestry individuals | G | NR | 7E-13 | 12.155 | rs261332 | 0.1872 | phosphatidylethanolamine measurement (EFO:0010228) |
PMID:34503513 |
None Available | GCST90060689 | Phosphatidylethanolamine(36:4)_[M-H]1- levels | 5,662 Pakistani ancestry individuals | T | NR | 7E-13 | 12.155 | rs261332 | 0.0493 | phosphatidylethanolamine measurement (EFO:0010228) |
PMID:34503513 |
None Available | GCST90060696 | Phosphatidylcholine(33:2)_[M+H]1+/Phosphatidylethanolamine(36:2)_[M+H]1+/Phosphatidate(38:3)_[M+NH4]1+ levels | 5,662 Pakistani ancestry individuals | A | NR | 7E-13 | 12.155 | rs261332 | 0.1867 | phosphatidylcholine measurement (EFO:0010226) |
PMID:34503513 |
None Available | GCST90060790 | Phosphatidylcholine(37:6)_[M+H]1+/Phosphatidylethanolamine(40:6)_[M+H]1+/Phosphatidate(42:7)_[M+NH4]1+ levels | 5,662 Pakistani ancestry individuals | G | NR | 7E-13 | 12.155 | rs261332 | 0.187 | phosphatidylcholine measurement (EFO:0010226) |
PMID:34503513 |
None Available | GCST90060665 | Phosphatidylethanolamine(34:2)_[M+H]1+ levels | 5,662 Pakistani ancestry individuals | C | NR | 7E-13 | 12.155 | rs261332 | 0.0491 | phosphatidylethanolamine measurement (EFO:0010228) |
PMID:34503513 |
None Available | GCST90060692 | Phosphatidylcholine(33:3)_[M+H]1+/Phosphatidylethanolamine(36:3)_[M+H]1+/Phosphatidate(38:4)_[M+NH4]1+ levels | 5,662 Pakistani ancestry individuals | C | NR | 7E-13 | 12.155 | rs261332 | 0.1874 | phosphatidylcholine measurement (EFO:0010226) |
PMID:34503513 |
None Available | GCST90060777 | Phosphatidylethanolamine(40:7)_[M-H]1- levels | 5,662 Pakistani ancestry individuals | T | NR | 7E-13 | 12.155 | rs261332 | 0.0851 | phosphatidylethanolamine measurement (EFO:0010228) |
PMID:34503513 |
None Available | GCST90060733 | Phosphatidylethanolamine(38:5)_[M-H]1- levels | 5,662 Pakistani ancestry individuals | G | NR | 7E-13 | 12.155 | rs261332 | 0.0802 | phosphatidylethanolamine measurement (EFO:0010228) |
PMID:34503513 |
None Available | GCST90060738 | Phosphatidylcholine(35:4)_[M+H]1+/Phosphatidylethanolamine(38:4)_[M+H]1+/Phosphatidate(40:5)_[M+NH4]1+ levels | 5,662 Pakistani ancestry individuals | G | NR | 7E-13 | 12.155 | rs261332 | 0.0574 | phosphatidylcholine measurement (EFO:0010226) |
PMID:34503513 |
GWAS1539111_H | GCST90092918 | Cholesteryl ester levels in medium VLDL | 115,082 European ancestry individuals | A | 0.209008 | 2E-16 | 15.699 | rs261332 | 0.0414943 | cholesteryl ester measurement (EFO:0010351) obsolete_vldl cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1542202_H | GCST90092916 | Cholesterol levels in medium VLDL | 115,082 European ancestry individuals | A | 0.209008 | 1E-16 | 16 | rs261332 | 0.042031 | total cholesterol measurement (EFO:0004574) obsolete_vldl cholesterol measurement (EFO:0008317) |
PMID:35213538 |
GWAS1545866_H | GCST90092860 | Free cholesterol levels in large LDL | 115,082 European ancestry individuals | A | 0.209008 | 2E-13 | 12.699 | rs261332 | 0.0366397 | free cholesterol measurement (EFO:0008591) low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:35213538 |
None Available | GCST90091641 | Fasting triglycerides levels in very small VLDL | null | G | 0.79840448 | 5E-8 | 7.302 | rs261332 | 0.140891 | triglyceride measurement (EFO:0004530) obsolete_vldl cholesterol measurement (EFO:0008317) |
PMID:34610981 |
GWAS1547827_H | GCST90091673 | Postprandial triglycerides levels in IDL | null | G | 0.798003912 | 2E-22 | 21.699 | rs261332 | 0.260961 | triglyceride measurement (EFO:0004530) intermediate density lipoprotein measurement (EFO:0008595) |
PMID:34610981 |
GWAS1548514_H | GCST90091743 | Postprandial triglycerides levels in small LDL | null | G | 0.797935358 | 7E-12 | 11.155 | rs261332 | 0.184467 | low density lipoprotein triglyceride measurement (EFO:0009946) |
PMID:34610981 |
GWAS1550459_H | GCST90091603 | Fasting triglycerides levels in small LDL | null | G | 0.798485938 | 1E-13 | 13 | rs261332 | 0.191671 | low density lipoprotein triglyceride measurement (EFO:0009946) |
PMID:34610981 |
GWAS1566805_H | GCST90010361 | High density lipoprotein cholesterol levels | 29,902 European ancestry individuals | A | 0.2 | 3E-25 | 24.523 | rs261332 | 1.58 | high density lipoprotein cholesterol measurement (EFO:0004612) |
PMID:31566214 |
GWAS1567137_H | GCST90010363 | Total cholesterol levels | 29,902 European ancestry individuals | A | 0.2 | 2E-10 | 9.699 | rs261332 | 2.39 | total cholesterol measurement (EFO:0004574) |
PMID:31566214 |
GWAS1583734_H | GCST90010824 | Phosphatidylcholine acyl-alkyl C32:2 levels | 16,839 Caucasian ancestry individuals | A | 0.1986 | 3E-12 | 11.523 | rs261332 | 6.961 | phosphatidylcholine measurement (EFO:0010226) |
PMID:33414548 |
GWAS1586764_H | GCST90179148 | Low-density lipoprotein levels (MTAG) | 361,194 European ancestry individuals | A | NR | 2E-310 | 309.699 | rs261332 | 0.063942 | low density lipoprotein cholesterol measurement (EFO:0004611) |
PMID:36376304 |
GWAS1599535_H | GCST90179149 | Triglyceride levels (MTAG) | 361,194 European ancestry individuals | A | NR | 4E-16 | 15.398 | rs261332 | 0.024689 | triglyceride measurement (EFO:0004530) |
PMID:36376304 |
GWAS1612109_H | GCST90269678 | Cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage (UKB data field 23581) | 85,701 European ancestry individuals | A | 0.208215 | 1E-58 | 58 | rs261332 | 0.0950629 | cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage (EFO:0022246) |
PMID:36764567 |
RGD Curation Notes
Note Type | Note | Reference |
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