GWAS1261628_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1261628_H (low density lipoprotein cholesterol measurement QTL GWAS1261628 (human)) Homo sapiens

Symbol: GWAS1261628_H
Name: low density lipoprotein cholesterol measurement QTL GWAS1261628 (human)
RGD ID: 597165554
Trait: low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 2.0E-18
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,438,954 - 58,438,955RGD_MAPPER_PIPELINEGRCh38
GRCh371558,731,153 - 58,731,154RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1261628_HHumanblood low density lipoprotein cholesterol level  IAGPrs261342405850206 GWAS_CATALOGPMID:35213538

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1261628_HHumanlow density lipoprotein cholesterol measurement  IAGPrs261342405850206 GWAS_CATALOGPMID:35213538

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
736877LIPClipase C, hepatic type155843199158569844Human
11084824LIPC-AS1LIPC antisense RNA 1155843490158498735Human


Peak: (rs261342)
Human AssemblyChrPosition (strand)Source
GRCh381558,438,954 - 58,438,955RGD_MAPPER_PIPELINE


1 to 10 of 46 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597066324GWAS1162398_Htriglyceride measurement QTL GWAS1162398 (human)7e-22triglyceride measurementblood triglyceride level (CMO:0000118)155843895458438955Human
597066323GWAS1162397_Htriglyceride measurement QTL GWAS1162397 (human)5e-19triglyceride measurementblood triglyceride level (CMO:0000118)155843895458438955Human
596970000GWAS1089519_Hremnant cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS1089519 (human)8e-15remnant cholesterol measurement, high density lipoprotein cholesterol measurement155843895458438955Human
597157010GWAS1253084_Hfatty acid measurement QTL GWAS1253084 (human)2e-45fatty acid measurement155843895458438955Human
597296669GWAS1392743_Hphosphatidylcholine measurement QTL GWAS1392743 (human)8e-11phosphatidylcholine measurement155843895458438955Human
597062494GWAS1158568_Htotal cholesterol measurement QTL GWAS1158568 (human)6e-30total cholesterol measurementblood total cholesterol level (CMO:0000051)155843895458438955Human
597125791GWAS1221865_Hphosphatidylethanolamine measurement QTL GWAS1221865 (human)7e-13phosphatidylethanolamine measurement155843895458438955Human
597262867GWAS1358941_Htriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS1358941 (human)2e-14triglycerides:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843895458438955Human
597153181GWAS1249255_Hlow density lipoprotein cholesterol measurement QTL GWAS1249255 (human)4e-17low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155843895458438955Human
597032537GWAS1128611_Hhigh density lipoprotein cholesterol measurement QTL GWAS1128611 (human)5e-49high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155843895458438955Human

1 to 10 of 46 rows


1 to 20 of 58 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1261628_H GCST90092963 Concentration of small LDL particles 115,082 European ancestry individuals G 0.220022 2E-18 17.699 rs261342 0.0437534 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS1119424_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.223 3E-94 93.523 rs261342 0.096 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS1119425_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.409 7E-10 9.155 rs261342 0.079 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS1119426_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.601 9E-8 7.046 rs261342 0.075 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS1119427_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 5E-105 104.302 rs261342 0.089 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS1128611_H GCST008685 HDL cholesterol levels up to 23,761 African ancestry individuals, 13,171 Asian ancestry individuals, up to 90,272 European ancestry individuals, 6,620 Hispanic individuals C 0.6497 5E-49 48.302 rs261342 0.0179 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30926973
GWAS1158568_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 6E-30 29.222 rs261342 0.057 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1158581_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.223 6E-29 28.222 rs261342 0.064 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1162397_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.223 5E-19 18.302 rs261342 0.046 triglyceride measurement (EFO:0004530)
 PMID:29507422
GWAS1162398_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 7E-22 21.155 rs261342 0.043 triglyceride measurement (EFO:0004530)
 PMID:29507422
GWAS687482_H GCST008702 Triglyceride levels up to 23,508 African ancestry individuals, 4,649 Asian ancestry individuals, up to 77,047 European ancestry individuals, 6,705 Hispanic individuals C 0.775 2E-13 12.699 rs261342 0.0235 triglyceride measurement (EFO:0004530)
 PMID:30926973
GWAS1216885_H GCST90060790 Phosphatidylcholine(37:6)_[M+H]1+/Phosphatidylethanolamine(40:6)_[M+H]1+/Phosphatidate(42:7)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals G NR 8E-13 12.097 rs261342 0.0432 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
GWAS1221865_H GCST90060690 Phosphatidylethanolamine(36:4)_[M+H]1+ levels 5,662 Pakistani ancestry individuals G NR 7E-13 12.155 rs261342 0.0761 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
GWAS747241_H GCST009391 Metabolite levels 2,076 European ancestry individuals ? NR 0.000005 5.302 rs261342 0.19505087 lysophosphatidylethanolamine 18:0 measurement (EFO:0010367)
 PMID:23823483
None Available GCST90060733 Phosphatidylethanolamine(38:5)_[M-H]1- levels 5,662 Pakistani ancestry individuals G NR 8E-13 12.097 rs261342 0.0767 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
None Available GCST90060665 Phosphatidylethanolamine(34:2)_[M+H]1+ levels 5,662 Pakistani ancestry individuals C NR 8E-13 12.097 rs261342 0.0432 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
None Available GCST90060689 Phosphatidylethanolamine(36:4)_[M-H]1- levels 5,662 Pakistani ancestry individuals A NR 7E-13 12.155 rs261342 0.0737 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
None Available GCST90060692 Phosphatidylcholine(33:3)_[M+H]1+/Phosphatidylethanolamine(36:3)_[M+H]1+/Phosphatidate(38:4)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals C NR 8E-13 12.097 rs261342 0.0432 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
None Available GCST90060738 Phosphatidylcholine(35:4)_[M+H]1+/Phosphatidylethanolamine(38:4)_[M+H]1+/Phosphatidate(40:5)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals G NR 7E-13 12.155 rs261342 0.0794 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
None Available GCST90060696 Phosphatidylcholine(33:2)_[M+H]1+/Phosphatidylethanolamine(36:2)_[M+H]1+/Phosphatidate(38:3)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals A NR 8E-13 12.097 rs261342 0.1865 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
1 to 20 of 58 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90092963 GWAS Catalog

Note Type Note Reference