GWAS1668256_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1668256_H (neutrophil count QTL GWAS1668256 (human)) Homo sapiens

Symbol: GWAS1668256_H
Name: neutrophil count QTL GWAS1668256 (human)
RGD ID: 597611396
Trait: neutrophil quantity   (VT:0000222)    
Measurement Type: blood neutrophil count   (CMO:0000030)    
LOD Score: Not Available
P Value: 6.0E-20
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381541,931,985 - 41,931,986RGD_MAPPER_PIPELINEGRCh38
GRCh371542,224,183 - 42,224,184RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1668256_HHumanblood neutrophil count  IAGPrs74587848405850206 GWAS_CATALOGPMID:39024449

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1668256_HHumanneutrophil quantity  IAGPrs74587848405850206 GWAS_CATALOGPMID:39024449

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1668256_HHumanneutrophil count  IAGPrs74587848405850206 GWAS_CATALOGPMID:39024449

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
734140EHD4EH domain containing 4154189593341972557Human


Peak: (rs74587848)
Human AssemblyChrPosition (strand)Source
GRCh381541,931,985 - 41,931,986RGD_MAPPER_PIPELINE


1 to 10 of 15 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
597603382GWAS1660242_Hneutrophil count QTL GWAS1660242 (human)6e-27neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)154193198541931986Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
597603820GWAS1660680_Hneutrophil count QTL GWAS1660680 (human)2e-26neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)154193198541931986Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
597605225GWAS1662085_Hneutrophil count QTL GWAS1662085 (human)6e-37neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)154193198541931986Human

1 to 10 of 15 rows


1 to 9 of 9 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1668256_H GCST90479711 neutrophil (absolute count, mean, inv-norm transformed) 73,258 African American or Afro-Caribbean individuals, 37,000 Hispanic or Latin American individuals, 3,002 East Asian ancestry individuals, 275,053 European ancestry individuals T 0.9007 6E-20 19.222 rs74587848 0.04902 neutrophil count (EFO:0004833)
 PMID:39024449
GWAS1637852_H GCST90479666 lymphocyte (fraction, maximum, inv-norm transformed) 81,257 African American or Afro-Caribbean individuals, 40,768 Hispanic or Latin American individuals, 4,294 East Asian ancestry individuals, 290,958 European ancestry individuals T 0.9011 1E-12 12 rs74587848 0.0345 lymphocyte count (EFO:0004587)
 PMID:39024449
GWAS1638876_H GCST90475505 monocyte (absolute count, minimum, inv-norm transformed) 259,625 European ancestry individuals T 0.8882 3E-44 43.523 rs74587848 0.07449 monocyte count (EFO:0005091)
 PMID:39024449
GWAS1660242_H GCST90475526 neutrophil (absolute count, maximum, inv-norm transformed) 274,370 European ancestry individuals T 0.8881 6E-27 26.222 rs74587848 0.05058 neutrophil count (EFO:0004833)
 PMID:39024449
GWAS1660680_H GCST90475532 neutrophil (absolute count, minimum, inv-norm transformed) 275,068 European ancestry individuals T 0.888 2E-26 25.699 rs74587848 0.05232 neutrophil count (EFO:0004833)
 PMID:39024449
GWAS1662085_H GCST90475529 neutrophil (absolute count, mean, inv-norm transformed) 275,053 European ancestry individuals T 0.888 6E-37 36.222 rs74587848 0.06163 neutrophil count (EFO:0004833)
 PMID:39024449
GWAS1667774_H GCST90479712 neutrophil (absolute count, minimum, inv-norm transformed) 74,049 African American or Afro-Caribbean individuals, 37,043 Hispanic or Latin American individuals, 3,003 East Asian ancestry individuals, 275,068 European ancestry individuals T 0.9008 8E-19 18.097 rs74587848 0.04671 neutrophil count (EFO:0004833)
 PMID:39024449
GWAS1747532_H GCST90480725 white blood cell count (WBC, minimum, inv-norm transformed) 108,942 African American or Afro-Caribbean individuals, 49,991 Hispanic or Latin American individuals, 5,838 East Asian ancestry individuals, 381,267 European ancestry individuals T 0.9014 4E-25 24.398 rs74587848 0.05251 leukocyte quantity (OBA:VT0000217)
 PMID:39024449
GWAS1760235_H GCST90476457 white blood cell count (WBC, minimum, inv-norm transformed) 381,267 European ancestry individuals T 0.888 8E-43 42.097 rs74587848 0.06193 leukocyte quantity (OBA:VT0000217)
 PMID:39024449
1 to 9 of 9 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90479711 GWAS Catalog

Note Type Note Reference