GWAS1580854_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1580854_H (glycerophospholipid measurement QTL GWAS1580854 (human)) Homo sapiens

Symbol: GWAS1580854_H
Name: glycerophospholipid measurement QTL GWAS1580854 (human)
RGD ID: 597484780
Trait: glycerophospholipid measurement
LOD Score: Not Available
P Value: 2.0E-16
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,388,755 - 58,388,756RGD_MAPPER_PIPELINEGRCh38
GRCh371558,680,954 - 58,680,955RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1580854_HHumanglycerophospholipid measurement  IAGPrs2043085405850206 GWAS_CATALOGPMID:35668104

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs2043085)
Human AssemblyChrPosition (strand)Source
GRCh381558,388,755 - 58,388,756RGD_MAPPER_PIPELINE


1 to 10 of 98 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597485471GWAS1581545_Hphosphatidylethanolamine measurement QTL GWAS1581545 (human)2e-25phosphatidylethanolamine measurement155838875558388756Human
597489306GWAS1585380_Hcholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS1585380 (human)2e-266cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155838875558388756Human
597525396GWAS1621470_Hphospholipids in medium HDL measurement QTL GWAS1621470 (human)3e-116blood HDL phospholipid amount (VT:0010504)155838875558388756Human
597485461GWAS1581535_Hphosphatidylethanolamine measurement QTL GWAS1581535 (human)5e-21phosphatidylethanolamine measurement155838875558388756Human
597525399GWAS1621473_Hcholesteryl ester measurement QTL GWAS1621473 (human)2e-42blood lipid amount (VT:0003949)155838875558388756Human
597483671GWAS1579745_Hcholesteryl ester measurement QTL GWAS1579745 (human)2e-13blood lipid amount (VT:0003949)155838875558388756Human
597517201GWAS1613275_Hapolipoprotein A 1 measurement QTL GWAS1613275 (human)5e-142apolipoprotein A 1 measurementblood apolipoprotein AI level (CMO:0000520)155838875558388756Human
597428370GWAS1524444_Hphosphatidylcholine measurement QTL GWAS1524444 (human)9e-39phosphatidylcholine measurement155838875558388756Human
597428627GWAS1524701_Hphosphatidylethanolamine measurement QTL GWAS1524701 (human)1e-14phosphatidylethanolamine measurement155838875558388756Human
597376905GWAS1472979_Hmetabolic syndrome QTL GWAS1472979 (human)1e-08metabolic syndrome155838875558388756Human

1 to 10 of 98 rows


1 to 20 of 115 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1580854_H GCST90024451 Phosphatidylglycerol (36:1) levels 4,492 European ancestry individuals C NR 2E-16 15.699 rs2043085 0.186 glycerophospholipid measurement (EFO:0007630)
 PMID:35668104
GWAS1743702_H GCST90314216 CPM/PCSK9 protein level ratio 43,509 European ancestry individuals ? NR 2E-55 54.699 rs2043085 0.106752 CPM/PCSK9 protein level ratio in blood (OBA:2054595)
 PMID:38412862
GWAS1758981_H GCST90093033 Free cholesterol to total lipids ratio in very small VLDL 115,082 European ancestry individuals T 0.387315 6E-58 57.222 rs2043085 0.0674712 free cholesterol:total lipids ratio (EFO:0020945)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1452019_H GCST002321 Lipid traits 3,451 Han Chinese ancestry individuals T 0.47 2E-8 7.699 rs2043085 0.012 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:24386095
GWAS1472979_H GCST001007 Metabolic syndrome (bivariate traits) 22,161 European ancestry individuals A NR 1E-8 8 rs2043085 0.17 metabolic syndrome (EFO:0000195)
 PMID:21386085
GWAS1487550_H GCST003219 Advanced age-related macular degeneration 16,144 European ancestry cases, 17,832 European ancestry controls ? NR 4E-15 14.398 rs2043085 1.1494253 atrophic macular degeneration (EFO:1001492)
age-related macular degeneration (EFO:0001365)
wet macular degeneration (EFO:0004683)
 PMID:26691988
GWAS1502818_H GCST90302052 Phospholipids to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.4086 5E-48 47.302 rs2043085 0.0579 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
GWAS1504674_H GCST90302100 Phospholipids to total lipids ratio in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.4086 2E-27 26.699 rs2043085 0.0432 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
GWAS1505723_H GCST90264287 Plasma 1-stearoyl-2-docosahexaenoyl-GPE (18:0/22:6)* levels in chronic kidney disease 4,946 European ancestry individuals C 0.63 3E-27 26.523 rs2043085 0.162 1-stearoyl-2-docosahexaenoyl-GPE (18:0/22:6) measurement (EFO:0800411)
 PMID:37277652
GWAS1513051_H GCST90060137 Lysophosphatidylethanolamine_16:0_[M-H]1- levels 13,814 British ancestry individuals T NR 4E-13 12.398 rs2043085 0.0793937 lysophosphatidylethanolamine measurement (EFO:0010225)
 PMID:34503513
GWAS1514349_H GCST90060319 Phosphatidylcholine_35:3_[M+H]1+/Phosphatidylethanolamine_38:3_[M+H]1+/Phosphatidate_40:4_[M+NH4]1+ levels 13,814 British ancestry individuals T NR 1E-10 10 rs2043085 0.0661351 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
GWAS1514667_H GCST90060312 Phosphatidylcholine_35:6_[M+H]1+/Phosphatidylethanolamine_38:6_[M+H]1+/Phosphatidate_40:7_[M+NH4]1+ levels 13,814 British ancestry individuals T NR 2E-93 92.699 rs2043085 0.25323 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
GWAS1514676_H GCST90060316 Phosphatidylcholine_35:4_[M+H]1+/Phosphatidylethanolamine_38:4_[M+H]1+/Phosphatidate_40:5_[M+NH4]1+ levels 13,814 British ancestry individuals T NR 3E-104 103.523 rs2043085 0.253871 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
GWAS1521408_H GCST90060690 Phosphatidylethanolamine(36:4)_[M+H]1+ levels 5,662 Pakistani ancestry individuals T NR 1E-13 13 rs2043085 0.0628 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
GWAS1521415_H GCST90060272 Phosphatidylethanolamine_36:4_[M-H]1- levels 13,814 British ancestry individuals T NR 2E-84 83.699 rs2043085 0.226443 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
GWAS1521483_H GCST90060310 Phosphatidylethanolamine_38:6_[M-H]1- levels 13,814 British ancestry individuals T NR 1E-99 99 rs2043085 0.249702 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
GWAS1521583_H GCST90060247 Phosphatidylethanolamine_34:2_[M-H]1- levels 13,814 British ancestry individuals T NR 2E-45 44.699 rs2043085 0.164985 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
None Available GCST90060738 Phosphatidylcholine(35:4)_[M+H]1+/Phosphatidylethanolamine(38:4)_[M+H]1+/Phosphatidate(40:5)_[M+NH4]1+ levels 5,662 Pakistani ancestry individuals G NR 1E-13 13 rs2043085 0.0682 phosphatidylcholine measurement (EFO:0010226)
 PMID:34503513
None Available GCST90060689 Phosphatidylethanolamine(36:4)_[M-H]1- levels 5,662 Pakistani ancestry individuals T NR 1E-13 13 rs2043085 0.0731 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:34503513
GWAS1522056_H GCST90060199 Diacylglycerol_38:6_[M+H-H2O]1+ levels 13,814 British ancestry individuals T NR 4E-21 20.398 rs2043085 0.095905 diglyceride measurement (EFO:0010223)
 PMID:34503513
1 to 20 of 115 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90024451 GWAS Catalog

Note Type Note Reference