GWAS1357576_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1357576_H (cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS1357576 (human)) Homo sapiens

Symbol: GWAS1357576_H
Name: cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS1357576 (human)
RGD ID: 597261502
Trait: cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 9.0E-17
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381543,434,427 - 43,434,428RGD_MAPPER_PIPELINEGRCh38
GRCh371543,726,625 - 43,726,626RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1357576_HHumanblood high density lipoprotein cholesterol level  IAGPrs150844304405850206 GWAS_CATALOGPMID:35213538

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1357576_HHumancholesteryl esters:total lipids ratio  IAGPrs150844304405850206 GWAS_CATALOGPMID:35213538
GWAS1357576_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs150844304405850206 GWAS_CATALOGPMID:35213538

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1317577TP53BP1tumor protein p53 binding protein 1154340306143510640Human


Peak: (rs150844304)
Human AssemblyChrPosition (strand)Source
GRCh381543,434,427 - 43,434,428RGD_MAPPER_PIPELINE


1 to 10 of 117 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597174425GWAS1270499_Htriglycerides in HDL measurement QTL GWAS1270499 (human)4e-23blood HDL triglyceride amount (VT:0010698)154343442743434428Human
597180569GWAS1276643_Htriglycerides in large VLDL measurement QTL GWAS1276643 (human)3e-18triglycerides in large VLDL measurementblood very low density lipoprotein triglyceride level (CMO:0002688)154343442743434428Human
597024663GWAS1120737_Hhigh density lipoprotein cholesterol measurement QTL GWAS1120737 (human)5e-21blood lipid amount (VT:0003949)blood high density lipoprotein cholesterol level (CMO:0000052)154343442743434428Human
596960406GWAS1079925_Hhematocrit QTL GWAS1079925 (human)1e-24hematocrit154343442743434428Human
597026192GWAS1122266_Hhigh density lipoprotein cholesterol measurement QTL GWAS1122266 (human)1e-11total lipids in medium VLDL154343442743434428Human
597185693GWAS1281767_Htriglycerides in large LDL measurement QTL GWAS1281767 (human)2e-28blood LDL triglyceride amount (VT:0010699)154343442743434428Human
406946378GWAS595354_Hhematocrit QTL GWAS595354 (human)6e-34hematocrithematocrit (CMO:0000037)154343442743434428Human
597186707GWAS1282781_Htriglycerides in very large HDL measurement QTL GWAS1282781 (human)1e-16blood HDL triglyceride amount (VT:0010698)154343442743434428Human
597048474GWAS1144548_HC-reactive protein measurement QTL GWAS1144548 (human)4e-32C-reactive protein measurementblood C-reactive protein level (CMO:0003160)154343442743434428Human
597024664GWAS1120738_Hhigh density lipoprotein cholesterol measurement QTL GWAS1120738 (human)1e-24hematocrithematocrit (CMO:0000037)154343442743434428Human

1 to 10 of 117 rows


1 to 20 of 180 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1357576_H GCST90093007 Cholesteryl esters to total lipids ratio in very large HDL 115,056 European ancestry individuals A 0.974323 9E-17 16.046 rs150844304 0.107959 cholesteryl esters:total lipids ratio (EFO:0020944)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS1120737_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals A 0.97 5E-21 20.302 rs150844304 0.104 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS1120738_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals A NR 1E-24 24 rs150844304 0.108 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS1640438_H GCST90479669 mean corpuscular hemoglobin concentration (MCHC, maximum, inv-norm transformed) 114,857 African American or Afro-Caribbean individuals, 55,793 Hispanic or Latin American individuals, 5,943 East Asian ancestry individuals, 407,343 European ancestry individuals A 0.9775 2E-16 15.699 rs150844304 0.08 mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:39024449
GWAS1641318_H GCST90479672 mean corpuscular hemoglobin (MCH, maximum, inv-norm transformed) 114,852 African American or Afro-Caribbean individuals, 55,783 Hispanic or Latin American individuals, 5,942 East Asian ancestry individuals, 407,288 European ancestry individuals A 0.9775 1E-11 11 rs150844304 0.07879 mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:39024449
GWAS1641537_H GCST90479673 mean corpuscular hemoglobin (MCH, mean, inv-norm transformed) 114,855 African American or Afro-Caribbean individuals, 55,792 Hispanic or Latin American individuals, 5,944 East Asian ancestry individuals, 407,342 European ancestry individuals A 0.9775 4E-12 11.398 rs150844304 0.08125 mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:39024449
GWAS1121738_H GCST008084 HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers C NR 3E-35 34.523 rs150844304 N/A alcohol drinking (EFO:0004329)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS1121743_H GCST008084 HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers C NR 8E-33 32.097 rs150844304 N/A alcohol drinking (EFO:0004329)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS1121902_H GCST008087 Triglyceride levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals C NR 8E-29 28.097 rs150844304 0.09 triglyceride measurement (EFO:0004530)
 PMID:30698716
GWAS1122052_H GCST008087 Triglyceride levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals C NR 3E-27 26.523 rs150844304 0.093 triglyceride measurement (EFO:0004530)
 PMID:30698716
GWAS1122266_H GCST008070 HDL cholesterol levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals C NR 1E-11 11 rs150844304 0.03194 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS1122471_H GCST008085 HDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals C NR 2E-20 19.699 rs150844304 0.033 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS1123306_H GCST008070 HDL cholesterol levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals C NR 4E-11 10.398 rs150844304 0.03565 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS1124844_H GCST008085 HDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals C NR 7E-19 18.155 rs150844304 0.034 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS1134704_H GCST010242 HDL cholesterol levels 403,943 European ancestry individuals A 0.974093 2E-51 50.699 rs150844304 0.0904093 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:32203549
GWAS1135780_H GCST010241 Apolipoprotein A1 levels 393,193 European ancestry individuals A 0.974051 3E-34 33.523 rs150844304 0.075233 apolipoprotein A 1 measurement (EFO:0004614)
 PMID:32203549
GWAS595354_H GCST90002383 Hematocrit 408,112 British individuals C 0.025291 6E-34 33.222 rs150844304 0.08552511 hematocrit (EFO:0004348)
 PMID:32888494
GWAS601251_H GCST003661 Triglycerides 41,142 European ancestry individuals, 705 East Asian ancestry individuals, 6,287 African American individuals, 1,415 Hispanic individuals A 0.96 1E-15 15 rs150844304 0.066 triglyceride measurement (EFO:0004530)
 PMID:27036123
GWAS1143718_H GCST007069 Red blood cell count approximately 445,000 European ancestry individuals ? NR 1E-12 12 rs150844304 N/A erythrocyte count (EFO:0004305)
 PMID:30595370
GWAS1144548_H GCST009777 C-reactive protein levels 418,642 British ancestry individuals A 0.975286 4E-32 31.398 rs150844304 0.0769327 C-reactive protein measurement (EFO:0004458)
 PMID:31900758
1 to 20 of 180 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90093007 GWAS Catalog

Note Type Note Reference