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Gene: SHF (Src homology 2 domain containing F) Homo sapiens
Symbol: SHF
Name: Src homology 2 domain containing F
RGD ID: 1602197
Description: Predicted to have phosphotyrosine residue binding activity. Predicted to be involved in apoptotic process; PARTICIPATES IN platelet-derived growth factor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; antirheumatic drug.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CTD-2651B20.7; MGC126650; MGC126652; SH2 domain-containing adapter protein F
Mus musculus (house mouse) : Shf (Src homology 2 domain containing F)  MGI  Alliance
Rattus norvegicus (Norway rat) : Shf (Src homology 2 domain containing F)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Shf (Src homology 2 domain containing F)
Pan paniscus (bonobo/pygmy chimpanzee) : SHF (Src homology 2 domain containing F)
Canis lupus familiaris (dog) : SHF (Src homology 2 domain containing F)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Shf (Src homology 2 domain containing F)
Sus scrofa (pig) : SHF (Src homology 2 domain containing F)
Chlorocebus sabaeus (African green monkey) : SHF (Src homology 2 domain containing F)
Heterocephalus glaber (naked mole-rat) : Shf (Src homology 2 domain containing F)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1545,167,214 - 45,201,175 (-)EnsemblGRCh38hg38GRCh38
GRCh381545,167,214 - 45,201,116 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371545,459,412 - 45,493,373 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361543,246,704 - 43,280,665 (-)NCBINCBI36hg18NCBI36
Celera1522,350,695 - 22,384,650 (-)NCBI
Cytogenetic Map15q21.1NCBI
HuRef1522,283,482 - 22,317,406 (-)NCBIHuRef
CHM1_11545,578,088 - 45,611,982 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SHF
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1602197
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.