BUB1B (BUB1 mitotic checkpoint serine/threonine kinase B) - Rat Genome Database

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Gene: BUB1B (BUB1 mitotic checkpoint serine/threonine kinase B) Homo sapiens
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Symbol: BUB1B
Name: BUB1 mitotic checkpoint serine/threonine kinase B
RGD ID: 1316316
HGNC Page HGNC:1149
Description: Predicted to enable protein kinase activity. Involved in mitotic spindle assembly checkpoint signaling and negative regulation of ubiquitin-protein transferase activity. Located in several cellular components, including mitotic checkpoint complex; perinuclear region of cytoplasm; and spindle. Part of outer kinetochore. Colocalizes with kinetochore. Implicated in colorectal cancer and mosaic variegated aneuploidy syndrome 1. Biomarker of gallbladder cancer; pancreatic cancer; and tongue carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: Bub1A; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 homolog beta; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; SSK1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381540,161,069 - 40,221,123 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1540,161,023 - 40,221,123 (+)EnsemblGRCh38hg38GRCh38
GRCh371540,453,270 - 40,513,324 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361538,240,530 - 38,300,629 (+)NCBINCBI36Build 36hg18NCBI36
Build 341538,240,529 - 38,300,627NCBI
Celera1517,219,190 - 17,279,313 (+)NCBICelera
Cytogenetic Map15q15.1NCBI
HuRef1517,296,260 - 17,356,314 (+)NCBIHuRef
CHM1_11540,573,169 - 40,633,290 (+)NCBICHM1_1
T2T-CHM13v2.01537,967,956 - 38,028,008 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model